IT8321461A0 - Ammidine ad attivita' farmaceutica e relativo procedimento di fabbricazione. - Google Patents

Ammidine ad attivita' farmaceutica e relativo procedimento di fabbricazione.

Info

Publication number: IT8321461A0
Authority: IT; Italy
Prior art keywords: amidines; manufacturing procedure; pharmaceutical activity; related manufacturing; pharmaceutical
Prior art date: 1982-06-04

Application number

IT8321461A

Other languages

English (en)

Other versions

IT1206452B (it

Inventor

Dolatrai Mohanlal Vyas

Takushi Kaneko

Terrence William Doyle

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-04

Filing date

1983-06-03

Publication date

1983-06-03

1983-06-03 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1983-06-03 Publication of IT8321461A0 publication Critical patent/IT8321461A0/it

1989-04-27 Application granted granted Critical

1989-04-27 Publication of IT1206452B publication Critical patent/IT1206452B/it

Links

150000001409 amidines Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT8321461A 1982-06-04 1983-06-03 Ammidine ad attivita' farmaceutica e relativo procedimento di fabbricazione. IT1206452B (it)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US38514982A	1982-06-04	1982-06-04
US06/492,903 US4487769A (en)	1982-06-04	1983-05-09	Amidines

Publications (2)

Publication Number	Publication Date
IT8321461A0 true IT8321461A0 (it)	1983-06-03
IT1206452B IT1206452B (it)	1989-04-27

Family

ID=27010906

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT8321461A IT1206452B (it)	1982-06-04	1983-06-03	Ammidine ad attivita' farmaceutica e relativo procedimento di fabbricazione.

Country Status (27)

Country	Link
US (1)	US4487769A (it)
KR (1)	KR870000932B1 (it)
AR (1)	AR241438A1 (it)
AT (1)	AT394853B (it)
AU (1)	AU571179B2 (it)
CA (1)	CA1230333A (it)
CH (1)	CH657856A5 (it)
DD (1)	DD210275A5 (it)
DE (1)	DE3319992A1 (it)
DK (2)	DK161023C (it)
ES (3)	ES8407493A1 (it)
FI (1)	FI78700C (it)
FR (1)	FR2528048B1 (it)
GB (1)	GB2121796B (it)
GR (1)	GR78277B (it)
HU (1)	HU198936B (it)
IE (1)	IE56107B1 (it)
IL (1)	IL68852A0 (it)
IT (1)	IT1206452B (it)
LU (1)	LU84843A1 (it)
NL (1)	NL8301949A (it)
NO (1)	NO161676C (it)
NZ (1)	NZ204352A (it)
OA (1)	OA07452A (it)
PT (1)	PT76810B (it)
SE (1)	SE455504B (it)
YU (2)	YU42866B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ206932A (en) *	1983-02-07	1987-08-31	University Patents Inc	Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) *	1983-04-11	1989-02-07	Bristol-Myers Company	Amino disulfides
US4579737A (en) *	1983-05-09	1986-04-01	Bristol-Myers Company	Bis-amidines
US4642352A (en) *	1983-12-23	1987-02-10	Bristol-Myers Company	Acylamino mitosanes
AU581673B2 (en) *	1984-09-04	1989-03-02	Bristol-Myers Company	Substituted 7-oxomitosanes
US4814445A (en) *	1984-09-04	1989-03-21	Bristol-Myers Company	Process for preparing mitomycin analogs
JPS61176590A (ja) *	1985-01-31	1986-08-08	Kyowa Hakko Kogyo Co Ltd	７−ｎ−アミノメチレンマイトマイシン誘導体、製造法及び抗腫瘍剤
AT396688B (de) *	1985-02-21	1993-11-25	Bristol Myers Squibb Co	Verfahren zur herstellung von kristallinem
US4639528A (en) *	1985-02-21	1987-01-27	Bristol-Myers Company	Crystalline form of 7-(dimethylaminomethylene-amino-9a-methoxymitosane
ZA86308B (en) *	1985-02-25	1986-11-26	Bristol Myers Co	In-vial deposition of 7-(dimethylaminomethylene)amino-9a-methoxy-mitosane
US4652644A (en) *	1985-04-29	1987-03-24	Bristol-Myers Company	Process for preparation of N7 -amidino substituted mitomycin C derivatives
JPH066592B2 (ja) *	1986-04-18	1994-01-26	協和醗酵工業株式会社	マイトマイシン誘導体
US4791113A (en) *	1986-05-14	1988-12-13	Kyowa Hakko Kogyo Kabushiki Kaisha	Mitomycin derivatives as antileukemia agents
JPS6354380A (ja) *	1986-08-26	1988-03-08	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
JPS63150282A (ja) *	1986-12-13	1988-06-22	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
IL86665A0 (en) *	1987-06-12	1988-11-30	Bristol Myers Co	Mitomycin analogs
IL89203A0 (en) *	1988-02-11	1989-09-10	Univ Houston	7-substituted hydrazine mitomycin analogs and pharmaceutical compositions containing them

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3660578A (en) *	1957-04-06	1972-05-02	Kyowa Hakko Kogyo Kk	Mitomycin c
US3121084A (en) *	1962-09-17	1964-02-11	Du Pont	Selected n, n, n'-trisubstituted amidines and their preparation by reaction of compounds with-nh2 groups with amide acetals
NL129868C (it) *	1963-06-07
DE1570029A1 (de) *	1964-07-09	1970-04-09	Kyowa Hakko Kogyo Kk	Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) *	1964-08-25	1969-01-07	Kyowa Hakko Kogyo Kk	7-substituted mitomycin a
US3332944A (en) *	1964-11-02	1967-07-25	American Cyanamid Co	Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) *	1977-08-31	1979-03-24	Kyowa Hakko Kogyo Co Ltd	Mitomycin c derivatives
US4268676A (en) *	1979-12-05	1981-05-19	University Patents, Inc.	Mitomycin analogs
NZ206932A (en) *	1983-02-07	1987-08-31	University Patents Inc	Certain 6-(heterocyclyl or amino) mitosanes and pharmaceutical compositions
US4803212A (en) *	1983-04-11	1989-02-07	Bristol-Myers Company	Amino disulfides
JPS6073085A (ja) *	1983-09-28	1985-04-25	Matsushita Refrig Co	ロ−タリ−コンプレツサ
US4642352A (en) *	1983-12-23	1987-02-10	Bristol-Myers Company	Acylamino mitosanes

1983
- 1983-05-09 US US06/492,903 patent/US4487769A/en not_active Expired - Fee Related
- 1983-05-25 NZ NZ204352A patent/NZ204352A/en unknown
- 1983-05-26 AU AU15014/83A patent/AU571179B2/en not_active Ceased
- 1983-05-27 FR FR8308807A patent/FR2528048B1/fr not_active Expired
- 1983-06-01 FI FI831972A patent/FI78700C/fi not_active IP Right Cessation
- 1983-06-01 IL IL68852A patent/IL68852A0/xx not_active IP Right Cessation
- 1983-06-01 DE DE19833319992 patent/DE3319992A1/de active Granted
- 1983-06-01 NL NL8301949A patent/NL8301949A/nl not_active Application Discontinuation
- 1983-06-02 GB GB08315205A patent/GB2121796B/en not_active Expired
- 1983-06-03 DK DK253083A patent/DK161023C/da not_active IP Right Cessation
- 1983-06-03 IE IE1320/83A patent/IE56107B1/en not_active IP Right Cessation
- 1983-06-03 ES ES522948A patent/ES8407493A1/es not_active Expired
- 1983-06-03 HU HU834817A patent/HU198936B/hu unknown
- 1983-06-03 DD DD83251741A patent/DD210275A5/de not_active IP Right Cessation
- 1983-06-03 PT PT76810A patent/PT76810B/pt not_active IP Right Cessation
- 1983-06-03 LU LU84843A patent/LU84843A1/fr unknown
- 1983-06-03 NO NO832022A patent/NO161676C/no unknown
- 1983-06-03 OA OA58018A patent/OA07452A/xx unknown
- 1983-06-03 GR GR71552A patent/GR78277B/el unknown
- 1983-06-03 YU YU1241/83A patent/YU42866B/xx unknown
- 1983-06-03 IT IT8321461A patent/IT1206452B/it active
- 1983-06-03 CA CA000429642A patent/CA1230333A/en not_active Expired
- 1983-06-03 SE SE8303160A patent/SE455504B/sv not_active IP Right Cessation
- 1983-06-04 KR KR1019830002499A patent/KR870000932B1/ko not_active IP Right Cessation
- 1983-06-06 AT AT0206483A patent/AT394853B/de not_active IP Right Cessation
- 1983-06-10 CH CH3099/83A patent/CH657856A5/de not_active IP Right Cessation
1984
- 1984-02-09 ES ES529585A patent/ES8504199A1/es not_active Expired
- 1984-02-09 ES ES529584A patent/ES529584A0/es active Granted
1985
- 1985-08-16 AR AR85301300A patent/AR241438A1/es active
1986
- 1986-02-05 YU YU164/86A patent/YU43427B/xx unknown
1990
- 1990-11-27 DK DK281490A patent/DK162167C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO832022L (no)	1983-12-05
NO161676B (no)	1989-06-05
AU1501483A (en)	1983-12-08
IL68852A0 (en)	1983-10-31
DK253083A (da)	1983-12-05
AU571179B2 (en)	1988-04-14
YU42866B (en)	1988-12-31
DK162167B (da)	1991-09-23
GB2121796B (en)	1986-03-12
SE8303160D0 (sv)	1983-06-03
SE8303160L (sv)	1984-01-27
FI831972A0 (fi)	1983-06-01
HU198936B (en)	1989-12-28
AR241438A1 (es)	1992-07-31
IE56107B1 (en)	1991-04-24
GB2121796A (en)	1984-01-04
YU124183A (en)	1986-06-30
DE3319992A1 (de)	1983-12-08
DK253083D0 (da)	1983-06-03
ES529585A0 (es)	1985-04-16
ATA206483A (de)	1991-12-15
DK162167C (da)	1992-02-24
NO161676C (no)	1989-09-13
IE831320L (en)	1983-12-04
OA07452A (fr)	1984-03-31
SE455504B (sv)	1988-07-18
FI78700C (fi)	1989-09-11
FI831972L (fi)	1983-12-05
DK281490A (da)	1990-11-27
CA1230333A (en)	1987-12-15
GR78277B (it)	1984-09-26
YU43427B (en)	1989-06-30
PT76810B (en)	1986-04-09
ES522948A0 (es)	1984-10-01
FI78700B (fi)	1989-05-31
FR2528048B1 (fr)	1986-12-12
DK281490D0 (da)	1990-11-27
FR2528048A1 (fr)	1983-12-09
NZ204352A (en)	1987-07-31
ES8504198A1 (es)	1985-04-16
DK161023B (da)	1991-05-21
GB8315205D0 (en)	1983-07-06
ES8504199A1 (es)	1985-04-16
NL8301949A (nl)	1984-01-02
IT1206452B (it)	1989-04-27
PT76810A (en)	1983-07-01
ES8407493A1 (es)	1984-10-01
AT394853B (de)	1992-07-10
YU16486A (en)	1986-12-31
US4487769A (en)	1984-12-11
DK161023C (da)	1991-10-28
CH657856A5 (de)	1986-09-30
LU84843A1 (fr)	1984-03-07
KR840005143A (ko)	1984-11-03
DE3319992C2 (it)	1991-11-21
DD210275A5 (de)	1984-06-06
KR870000932B1 (ko)	1987-05-11
ES529584A0 (es)	1985-04-16

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19950630

Publication	Publication Date	Title
NL188642C (nl)	1992-08-17	3-aminoalkyl-1h-indool-5-methaansulfonamideverbinding en farmaceutisch preparaat met halsslagader-vernauwende werking.
DE3580304D1 (de)	1990-12-06	Arzneimittel.
NO861776L (no)	1986-11-07	Bor-karbid-baserte kermeter, samt fremstilling derav.
IT8422142A0 (it)	1984-07-31	Procedimento di preparazione. cefem composti ad azione farmaceutica e relativo
IT8321461A0 (it)	1983-06-03	Ammidine ad attivita' farmaceutica e relativo procedimento di fabbricazione.
IT8423086A0 (it)	1984-10-10	Composizione farmaceutica o dietetica ad elevata attivita'antitrombotica e antiarteriosclerotica.
IT8521225A0 (it)	1985-06-20	N-benzidrildiazacicloalchil-alcanilidi ad attivita' antianafilattica ed antibroncospastica.
IT8520973A0 (it)	1985-05-30	Benzoil-uree ad attivita'insetticida.
IT8324035A0 (it)	1983-12-05	Cefem composti ad attivita'farmaceutica e procedimenti per laloro preparazione.
IT8522744A0 (it)	1985-11-07	Eteri sostituiti con bicicloeptano ad attivita' farmaceutica.
IT8220259A0 (it)	1982-03-18	Ammido-ammino acidi ad attivita'farmacologica e relativo procedimento di preparazione.
IT1187756B (it)	1987-12-23	Isoindolinil-alchil-piperazine ad attivita' farmaceutica
IT8621393A0 (it)	1986-08-01	Composizioni farmaceutiche ad azione vasodilatatrice e dantianossica.
NO881386D0 (no)	1988-03-29	Forstoff, samt fremstilling derav.
IT1208512B (it)	1989-07-10	Benzoil-uree ad attivita'insetticida.
IT8320744A0 (it)	1983-04-22	Benzoil-uree ad attivita'insetticida.
IT8621557A0 (it)	1986-08-29	Antibiotici peptidici ad attivita'antimicrobica ed antitumorale.
IT8424227A0 (it)	1984-12-21	Acilammino mitosani ad attivita'antitumorale e relativo procedimento di preparazione.
FI852658A0 (fi)	1985-07-04	Farmaceutiska aemnen.
IT8819791A0 (it)	1988-03-16	Peptidi ad attivita' farmaceutica.
IT8320745A0 (it)	1983-04-22	Benzoil-uree ad attivita'insetticida.
IT8619723A0 (it)	1986-03-12	Condensatore di disaccoppiamento erelativo procedimento di fabbricazione.
ATE8460T1 (de)	1984-08-15	Pharmazeutische praeparate und deren herstellung.
IT8420082A0 (it)	1984-03-16	Agenti ad attivita'antibroncospastica e composizioni farmaceutiche che li contengono.
IT1150194B (it)	1986-12-10	Formulazioni farmaceutiche ad attivita'antiinfiammatoria, analgesica,antipiretica e gastroprotettiva