IT7949678A0 - Procedimento per produrre acidi tio metil-3-cefem-4-carbossilici sostituiti come intermedi per cefalosporine - Google Patents

Procedimento per produrre acidi tio metil-3-cefem-4-carbossilici sostituiti come intermedi per cefalosporine

Info

Publication number: IT7949678A0
Authority: IT; Italy
Prior art keywords: cefem; cephalosporins; intermediates; procedure; carboxylic acids
Prior art date: 1978-07-06

Application number

IT7949678A

Other languages

English (en)

Other versions

IT1118889B (it

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-07-06

Filing date

1979-07-06

Publication date

1979-07-06

1979-07-06 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

1979-07-06 Publication of IT7949678A0 publication Critical patent/IT7949678A0/it

1986-03-03 Application granted granted Critical

1986-03-03 Publication of IT1118889B publication Critical patent/IT1118889B/it

Links

SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical class C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 title 1
229930186147 Cephalosporin Natural products 0.000 title 1
229940124587 cephalosporin Drugs 0.000 title 1
HOKIDJSKDBPKTQ-GLXFQSAKSA-N cephalosporin C Chemical compound S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(O)=O)[C@@H]12 HOKIDJSKDBPKTQ-GLXFQSAKSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IT7949678A 1978-07-06 1979-07-06 Procedimento per rpodurre acidi tiometil-3-cefem-4-carbossilici sostituiti come intermedi per cefalosporine IT1118889B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP53082377A JPS6027677B2 (ja)	1978-07-06	1978-07-06	７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法

Publications (2)

Publication Number	Publication Date
IT7949678A0 true IT7949678A0 (it)	1979-07-06
IT1118889B IT1118889B (it)	1986-03-03

Family

ID=13772884

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT7949678A IT1118889B (it)	1978-07-06	1979-07-06	Procedimento per rpodurre acidi tiometil-3-cefem-4-carbossilici sostituiti come intermedi per cefalosporine

Country Status (33)

Country	Link
US (1)	US4312986A (it)
JP (1)	JPS6027677B2 (it)
AR (1)	AR225289A1 (it)
AT (1)	AT370107B (it)
AU (1)	AU515683B2 (it)
BE (1)	BE877504A (it)
BG (1)	BG49615A3 (it)
CA (1)	CA1139744A (it)
CH (1)	CH641809A5 (it)
CS (1)	CS208116B2 (it)
DD (1)	DD144778A5 (it)
DE (1)	DE2926664C2 (it)
DK (1)	DK160942C (it)
EG (1)	EG14330A (it)
ES (1)	ES482252A1 (it)
FI (1)	FI74967C (it)
FR (1)	FR2430423A1 (it)
GB (1)	GB2027429B (it)
GR (1)	GR72517B (it)
HK (1)	HK8385A (it)
HU (1)	HU179804B (it)
IN (1)	IN151439B (it)
IT (1)	IT1118889B (it)
KE (1)	KE3424A (it)
MX (1)	MX5545E (it)
NL (1)	NL182146C (it)
NO (1)	NO152653C (it)
NZ (1)	NZ190938A (it)
PL (1)	PL123459B1 (it)
RO (1)	RO78358A (it)
SE (1)	SE444935B (it)
SU (1)	SU1105116A3 (it)
YU (1)	YU42948B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5543043A (en) *	1978-09-22	1980-03-26	Sankyo Co Ltd	Preparation of 3-substituted thiomethylcephalosporin derivative
JPS55139387A (en) *	1979-04-19	1980-10-31	Yamanouchi Pharmaceut Co Ltd	Novel synthetic method of 7-amino-3-heterocyclic thiomethyl-delta3-carboxylic acids
NZ198350A (en)	1980-09-25	1985-02-28	Toyama Chemical Co Ltd	Cephalosporins and intermediates;pharmaceutical compositions
EP0051824B1 (en) *	1980-11-11	1986-01-15	Takeda Chemical Industries, Ltd.	Improvement in the method for producing 7-aminocephem compounds
JPS6052754B2 (ja) *	1981-01-29	1985-11-21	山之内製薬株式会社	７−アミノ−３−ハロゲノメチル−△↑３−セフェム−４−カルボン酸類およびその製法
JPS57128705A (en) *	1981-02-04	1982-08-10	Mitsui Petrochem Ind Ltd	Vapor-phase polymerizing method of olefin
JPS58986A (ja) *	1981-05-07	1983-01-06	Fujisawa Pharmaceut Co Ltd	セフェム化合物
ES505092A0 (es) *	1981-09-01	1982-11-01	Gema Sa	Procedimiento para la preparacion de un acido 7-aminocefa- losporanido-3-substituido
EP0135683B1 (en) *	1981-09-10	1987-07-22	Takeda Chemical Industries, Ltd.	Method for production of cephalosporin compounds
KR100477763B1 (ko) *	2000-08-16	2005-03-21	주식회사 엔지켐	세파트리진 프로필렌글리콜 중간체의 신규한 제조방법
KR100432425B1 (ko) *	2000-11-16	2004-05-22	씨제이 주식회사	세펨 유도체 또는 그 염의 신규한 제조방법
US7335767B2 (en) *	2002-10-29	2008-02-26	Lupin Limited	Method for preparation of ceftiofur and salts thereof
AU2010279452B2 (en)	2009-08-07	2015-04-30	Swagelok Company	Low temperature carburization under soft vacuum
DK2804965T3 (da)	2012-01-20	2020-12-14	Swagelok Co	Samtidigt flow af aktiveringsgas ved lavtemperatur-karburering
CN106967091A (zh) *	2017-05-13	2017-07-21	山西千岫制药有限公司	一种头孢替安母核的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1795484U (de)	1959-04-21	1959-09-10	Richard Langer	Quertraeger fuer laengsdraehte zum abstuetzen von pflanzen, insbesondere weinreben.
NL130098C (it) *	1963-07-15
CH527215A (de) *	1967-04-15	1972-08-31	Fujisawa Pharmaceutical Co	Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
GB1381272A (en) *	1971-01-26	1975-01-22	Glaxo Lab Ltd	Cephalosporin compounds
JPS5116436B1 (it) *	1971-05-31	1976-05-24
ZA728331B (en)	1971-12-23	1974-06-26	Lilly Co Eli	Preparation of 3-alkylthiomethyl cephalosporins
US3840531A (en) *	1972-03-21	1974-10-08	Lilly Co Eli	Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
CA1015745A (en)	1972-06-27	1977-08-16	Fujisawa Pharmaceutical Co.	3-substituted-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
DK635474A (it) *	1974-02-05	1975-10-13	Ciba Geigy Ag
JPS5111782A (en)	1974-07-16	1976-01-30	Takeda Chemical Industries Ltd	77 aminosefuemujudotaino seizoho
US4150156A (en) *	1975-11-21	1979-04-17	Merck & Co., Inc.	7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
JPS6022719B2 (ja) *	1977-11-24	1985-06-03	富山化学工業株式会社	７−置換または非置換アミノ−３−置換チオメチルセフェムカルボン酸類の新規製造法
US4144391A (en) *	1977-03-07	1979-03-13	Eli Lilly And Company	Cephalosporin displacement reaction

1978
- 1978-07-06 JP JP53082377A patent/JPS6027677B2/ja not_active Expired
1979
- 1979-06-26 CA CA000330604A patent/CA1139744A/en not_active Expired
- 1979-06-26 AU AU48394/79A patent/AU515683B2/en not_active Expired
- 1979-06-28 GB GB7922450A patent/GB2027429B/en not_active Expired
- 1979-07-02 DE DE2926664A patent/DE2926664C2/de not_active Expired
- 1979-07-03 YU YU1618/79A patent/YU42948B/xx unknown
- 1979-07-04 FI FI792117A patent/FI74967C/fi not_active IP Right Cessation
- 1979-07-04 CS CS794713A patent/CS208116B2/cs unknown
- 1979-07-04 SU SU792786305A patent/SU1105116A3/ru active
- 1979-07-04 CH CH623579A patent/CH641809A5/de not_active IP Right Cessation
- 1979-07-04 IN IN689/CAL/79A patent/IN151439B/en unknown
- 1979-07-04 FR FR7917364A patent/FR2430423A1/fr active Granted
- 1979-07-04 EG EG408/79A patent/EG14330A/xx active
- 1979-07-05 DD DD79214150A patent/DD144778A5/de unknown
- 1979-07-05 ES ES482252A patent/ES482252A1/es not_active Expired
- 1979-07-05 DK DK284779A patent/DK160942C/da not_active IP Right Cessation
- 1979-07-05 US US06/054,917 patent/US4312986A/en not_active Expired - Lifetime
- 1979-07-05 BE BE196143A patent/BE877504A/fr unknown
- 1979-07-05 SE SE7905899A patent/SE444935B/sv unknown
- 1979-07-05 GR GR59516A patent/GR72517B/el unknown
- 1979-07-05 NL NLAANVRAGE7905246,A patent/NL182146C/xx not_active IP Right Cessation
- 1979-07-05 BG BG44219A patent/BG49615A3/xx unknown
- 1979-07-05 HU HU79TO1110A patent/HU179804B/hu unknown
- 1979-07-05 NO NO792237A patent/NO152653C/no unknown
- 1979-07-06 PL PL1979216906A patent/PL123459B1/pl unknown
- 1979-07-06 IT IT7949678A patent/IT1118889B/it active
- 1979-07-06 NZ NZ190938A patent/NZ190938A/xx unknown
- 1979-07-06 MX MX798161U patent/MX5545E/es unknown
- 1979-07-06 AR AR277229A patent/AR225289A1/es active
- 1979-07-06 AT AT0472779A patent/AT370107B/de not_active IP Right Cessation
- 1979-07-06 RO RO7998073A patent/RO78358A/ro unknown
1984
- 1984-07-20 KE KE3424A patent/KE3424A/xx unknown
1985
- 1985-01-31 HK HK83/85A patent/HK8385A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AT370107B (de)	1983-03-10
FI792117A (fi)	1980-01-07
YU161879A (en)	1982-10-31
JPS559048A (en)	1980-01-22
CS208116B2 (en)	1981-08-31
NO152653C (no)	1985-10-30
DK160942C (da)	1991-10-21
SE7905899L (sv)	1980-01-07
BE877504A (fr)	1980-01-07
ES482252A1 (es)	1980-04-01
JPS6027677B2 (ja)	1985-06-29
FR2430423B1 (it)	1983-05-13
EG14330A (en)	1983-09-30
FI74967C (fi)	1988-04-11
NL7905246A (nl)	1980-01-08
NZ190938A (en)	1981-10-19
PL216906A1 (it)	1980-04-21
SU1105116A3 (ru)	1984-07-23
NL182146C (nl)	1988-01-18
KE3424A (en)	1984-08-10
GB2027429A (en)	1980-02-20
GB2027429B (en)	1982-12-08
HK8385A (en)	1985-02-08
MX5545E (es)	1983-10-03
DE2926664C2 (de)	1983-10-20
NL182146B (nl)	1987-08-17
HU179804B (en)	1982-12-28
FI74967B (fi)	1987-12-31
FR2430423A1 (fr)	1980-02-01
DD144778A5 (de)	1980-11-05
DE2926664A1 (de)	1980-01-24
GR72517B (it)	1983-11-16
AU4839479A (en)	1980-01-10
CA1139744A (en)	1983-01-18
ATA472779A (de)	1981-10-15
DK284779A (da)	1980-02-11
SE444935B (sv)	1986-05-20
AU515683B2 (en)	1981-04-16
NO792237L (no)	1980-01-08
IT1118889B (it)	1986-03-03
BG49615A3 (en)	1991-12-16
YU42948B (en)	1989-02-28
PL123459B1 (en)	1982-10-30
IN151439B (it)	1983-04-23
RO78358A (ro)	1982-02-26
AR225289A1 (es)	1982-03-15
DK160942B (da)	1991-05-06
CH641809A5 (de)	1984-03-15
US4312986A (en)	1982-01-26
NO152653B (no)	1985-07-22

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19970521

Publication	Publication Date	Title
IT7927487A0 (it)	1979-11-22	Procedimento per la produzione di acidi treo-3-ammino-2-idrossibutanoilammi noacetici nonche' di loro nuovi intermedi.
BR7905337A (pt)	1980-05-20	Derivado acido carboxilico
IT7946846A0 (it)	1979-05-25	Procedimento per la produzione dimateriali composti
IT7825205A0 (it)	1978-06-30	Processo per l'ossidazione di composti aromatici sostituiti ad acidi carbossilici aromatici
IT7949678A0 (it)	1979-07-06	Procedimento per produrre acidi tio metil-3-cefem-4-carbossilici sostituiti come intermedi per cefalosporine
IT1120442B (it)	1986-03-26	Procedimento per produrre acidi arilpiruvici
IT1111686B (it)	1986-01-13	Procedimento per la produzione di cefalosporine
ES490132A0 (es)	1981-04-01	Procedimiento de produccion de derivados de acido acetico.
KR840004685A (ko)	1984-10-22	티아졸 유도체의 제조방법
IT7951128A0 (it)	1979-12-18	Procedimento per la produzione di metacroleina
IT1129244B (it)	1986-06-04	Procedimento per la produzione di acidi policarbossilici aromatici
IT1110479B (it)	1985-12-23	Processo per la preparazione dell acido 2-(6-metossi-2-naftil)-propionico
AT367748B (de)	1982-07-26	Verfahren zur kontinuierlichen herstellung von percarbonsaeuren
IT7948848A0 (it)	1979-04-26	Procedimento per produrre cefalosporine
IT7950547A0 (it)	1979-10-12	Procedimento per la produzione di acido di-n-protilacetico
IT1143581B (it)	1986-10-22	Procedimento per la produzione di acidi alfa-chetocarbossilici
IT7830163A0 (it)	1978-11-24	Sostituiti. procedimento per la fabbricazione di esteri basici di acidi idrossicicicloesancarbossilici
IT7949050A0 (it)	1979-05-15	Procedimento per la produzione di ferriti
IT7950548A0 (it)	1979-10-12	Procedimento per la produzione di acido di-n-protilacetico
IT1123732B (it)	1986-04-30	Procedimento migliorato per la produzione di acido ascorbico
IT1123749B (it)	1986-04-30	Procedimento per la produzione di acido tereftalico
IT7948358A0 (it)	1979-03-15	Procedimento per la produzione di acidi cianocarbossilici
IT1141139B (it)	1986-10-01	Procedimento per la produzione di acido isoftalico
NO792089L (no)	1979-12-28	Fremgangsmaate for kontinuerlig fremstilling av dinitroglykoluril
IT1129663B (it)	1986-06-11	Procedimento per la produzione di acidi arilalcanoici e nuovi intermedi relativi