IS5582A - Meta-asahringamínóbensósýrusambönd og afleiður þeirra reynast mótlyf við integríni. - Google Patents

Meta-asahringamínóbensósýrusambönd og afleiður þeirra reynast mótlyf við integríni.

Info

Publication number
IS5582A
IS5582A IS5582A IS5582A IS5582A IS 5582 A IS5582 A IS 5582A IS 5582 A IS5582 A IS 5582A IS 5582 A IS5582 A IS 5582A IS 5582 A IS5582 A IS 5582A
Authority
IS
Iceland
Prior art keywords
azahringaminobenzoic
integrin
antagonists
meta
acid compounds
Prior art date
Application number
IS5582A
Other languages
English (en)
Inventor
E. Rogers Thomas
G. Ruminski Peter
Original Assignee
G.D. Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by G.D. Searle & Co filed Critical G.D. Searle & Co
Publication of IS5582A publication Critical patent/IS5582A/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
    • C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS5582A 1998-03-04 2000-08-04 Meta-asahringamínóbensósýrusambönd og afleiður þeirra reynast mótlyf við integríni. IS5582A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3427098A 1998-03-04 1998-03-04
PCT/US1999/003281 WO1999044994A1 (en) 1998-03-04 1999-02-22 Meta-azacyclic amino benzoic acid compounds and derivatives thereof being integrin antagonists

Publications (1)

Publication Number Publication Date
IS5582A true IS5582A (is) 2000-08-04

Family

ID=21875345

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5582A IS5582A (is) 1998-03-04 2000-08-04 Meta-asahringamínóbensósýrusambönd og afleiður þeirra reynast mótlyf við integríni.

Country Status (29)

Country Link
EP (1) EP1060164A1 (is)
JP (1) JP2002505323A (is)
KR (1) KR20010041584A (is)
CN (1) CN1214011C (is)
AP (1) AP1244A (is)
AR (1) AR018139A1 (is)
AU (1) AU753230B2 (is)
BG (1) BG104740A (is)
BR (1) BR9908470A (is)
CA (1) CA2322207A1 (is)
EA (1) EA200000804A1 (is)
EE (1) EE200000506A (is)
GE (1) GEP20033118B (is)
HR (1) HRP20000574A2 (is)
HU (1) HUP0100865A3 (is)
ID (1) ID25591A (is)
IL (1) IL137653A0 (is)
IS (1) IS5582A (is)
MY (1) MY123908A (is)
NO (1) NO315703B1 (is)
NZ (1) NZ506598A (is)
OA (1) OA11530A (is)
PL (1) PL342726A1 (is)
SK (1) SK13002000A3 (is)
TR (1) TR200002542T2 (is)
UA (1) UA71906C2 (is)
WO (1) WO1999044994A1 (is)
YU (1) YU52000A (is)
ZA (1) ZA994406B (is)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9826174D0 (en) 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
WO2001079173A2 (en) 2000-04-17 2001-10-25 Celltech R & D Limited Enamine derivatives as cell adhesion molecules
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
US6921767B2 (en) * 2000-06-15 2005-07-26 Pharmacia Corporation Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
EP1305291A1 (en) 2000-08-02 2003-05-02 Celltech R&D Limited 3-substituted isoquinolin-1-yl derivatives
AU2003299600A1 (en) * 2002-12-20 2004-07-29 Pharmacia Corpration The r-isomer of beta amino acid compounds as integrin receptor antagonists derivatives
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
CA2612979A1 (en) * 2005-06-10 2006-12-21 Bipar Sciences, Inc. Parp modulators and treatment of cancer
JP2010520238A (ja) 2007-03-01 2010-06-10 マリンクロット インコーポレイテッド 統合された光活性低分子および統合された光活性低分子使用
JP4792124B1 (ja) * 2010-11-15 2011-10-12 エフイートレード株式会社 車両用保護フィルムの型取り方法、及び、車両用保護フィルムの製造方法
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
CA2878469A1 (en) 2012-07-18 2014-01-23 Saint Louis University Beta amino acid derivatives as integrin antagonists
US10328082B2 (en) 2014-05-30 2019-06-25 Pfizer Inc. Methods of use and combinations
EP3151670B1 (en) * 2014-06-04 2019-10-02 Monsanto Technology LLC 3,6-dichlorosalicylic acid compounds and related synthetic processes
ES2806276T3 (es) 2015-12-30 2021-02-17 Univ Saint Louis Derivados de ácido aminobenzoico meta-azaciclicos como antagonistas pan-integrina
JPWO2021230325A1 (is) 2020-05-14 2021-11-18
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2230209A1 (en) * 1995-08-30 1997-03-06 G.D. Searle & Co. Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists

Also Published As

Publication number Publication date
NO315703B1 (no) 2003-10-13
NO20004316L (no) 2000-11-06
JP2002505323A (ja) 2002-02-19
TR200002542T2 (tr) 2001-05-21
EE200000506A (et) 2002-04-15
KR20010041584A (ko) 2001-05-25
MY123908A (en) 2006-06-30
HUP0100865A2 (hu) 2001-08-28
NZ506598A (en) 2003-07-25
CN1214011C (zh) 2005-08-10
SK13002000A3 (sk) 2001-07-10
AR018139A1 (es) 2001-10-31
ID25591A (id) 2000-10-19
BG104740A (en) 2001-02-28
IL137653A0 (en) 2001-10-31
WO1999044994A1 (en) 1999-09-10
AU3294799A (en) 1999-09-20
HRP20000574A2 (en) 2001-08-31
AU753230B2 (en) 2002-10-10
GEP20033118B (en) 2003-11-25
EA200000804A1 (ru) 2001-04-23
NO20004316D0 (no) 2000-08-30
ZA994406B (en) 2000-02-11
CA2322207A1 (en) 1999-09-10
EP1060164A1 (en) 2000-12-20
BR9908470A (pt) 2000-12-05
AP1244A (en) 2004-02-04
HUP0100865A3 (en) 2001-11-28
AP2000001893A0 (en) 2000-09-30
PL342726A1 (en) 2001-07-02
CN1291978A (zh) 2001-04-18
UA71906C2 (en) 2005-01-17
OA11530A (en) 2004-05-17
YU52000A (sh) 2003-02-28

Similar Documents

Publication Publication Date Title
IS5582A (is) Meta-asahringamínóbensósýrusambönd og afleiður þeirra reynast mótlyf við integríni.
ATE299503T1 (de) Pyridin-3-carbonsäurederivate und ihre verwendung als zwischenprodukte
DE60123210D1 (de) Picolinsäure-derivate und ihre verwendung als fungizide
EE200200251A (et) Uued N-asabitsükloamiidi derivaadid ja nende kasutamine
SI1165516T1 (en) Heterocyclic urea and related compounds useful as anti-inflammatory agents
IS5744A (is) Nýjar 3-arýl-própíónsýruafleiður og -hliðstæður
DE60133897D1 (de) Substituierte chinazolin-derivate und deren verwendung als aurora-2-kinase inhibitoren
PT1140191E (pt) Combinacoes de inibidores de transporte do acido biliar e de derivados do acido nicotinico utilizados no quadro de perturbacoes cardiovasculares
EE200100403A (et) Indooli derivaadid ja nende kasutamine MCP-1 antagonistidena
EE200100373A (et) Bensoheterotsüklid ja nende kasutamine MEK inhibiitoritena
PT1119557E (pt) Derivados de indeno- nafto- e benzociclohepta-di-hidrotiazole sua preparacao e sua utilizacao como medicamentos anorecticos
DE69904073T2 (de) Oximderivate und ihre verwendung als latente saüre
NO20013665L (no) Kaliumsalt av (S)-omeprazol
DE69906754D1 (de) Einbringung von rauchmodifizierenden mitteln in rauchartikeln
EE200100131A (et) Süstelahuste parem stabiilsus
IS5562A (is) Nýjar díhýdroxýhexanósýru afleiður
DE60008807D1 (de) Binaphtol-monophosphorsäurederivate und deren Verwendung
DE69510228D1 (de) Piperidinessigsäurederivate und ihre verwendung als fibrinogenantagonistmittel
DE50008549D1 (de) Triazolotriazinone und ihre verwendung
DE69908614D1 (de) Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten
IS6752A (is) Afleiður tryptamíns og hliðstæð efnasambönd ásamtlyfjaforskriftum þeirra
DE60009265D1 (de) Herstellung wässeriger lösungen von formyltetrahydrofuran und hydraten davon
DK1228026T3 (da) 15-Hydroxyicosatetraensyrerelaterede forbindelser og fremgangsmåde til anvendelse
MA25653A1 (fr) Derives d'amides heterocycliques.
FI19992142A (fi) Vesineulattu kuitukangas, menetelmä sen valmistamiseksi ja sen käyttö