IS4352A - Sordaridín afleiður gegn sveppum - Google Patents

Sordaridín afleiður gegn sveppum

Info

Publication number
IS4352A
IS4352A IS4352A IS4352A IS4352A IS 4352 A IS4352 A IS 4352A IS 4352 A IS4352 A IS 4352A IS 4352 A IS4352 A IS 4352A IS 4352 A IS4352 A IS 4352A
Authority
IS
Iceland
Prior art keywords
sordaridine
against fungi
derivatives against
derivatives
fungi
Prior art date
Application number
IS4352A
Other languages
English (en)
Inventor
Ramon Ruiz Gomez Jose
Maria Bueno Calderon Jose
Garcia-Ochoa Dorado Silvestre
Teresa Fraile Gabaldon Maria
Castro Pichel Julia
Fiandor Roman Jose
Gargallo Viola Domingo
Carlos Cuevas Zurita Juan
Luis Lavandera Diaz Jose
Huss Sophie
Original Assignee
Glaxo Wellcome S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP94500173A external-priority patent/EP0712859A1/en
Priority claimed from EP94500175A external-priority patent/EP0711784A1/en
Application filed by Glaxo Wellcome S.A. filed Critical Glaxo Wellcome S.A.
Publication of IS4352A publication Critical patent/IS4352A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS4352A 1994-11-08 1996-06-10 Sordaridín afleiður gegn sveppum IS4352A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94500173A EP0712859A1 (en) 1994-11-08 1994-11-08 Antifungal Sordarin derivatives
EP94500175A EP0711784A1 (en) 1994-11-08 1994-11-08 Antifungal Sordarin derivatives
PCT/EP1995/004331 WO1996014326A1 (en) 1994-11-08 1995-11-06 Antifungal sordaridin derivatives

Publications (1)

Publication Number Publication Date
IS4352A true IS4352A (is) 1996-06-10

Family

ID=26137608

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4352A IS4352A (is) 1994-11-08 1996-06-10 Sordaridín afleiður gegn sveppum

Country Status (35)

Country Link
US (2) US5854280A (is)
EP (1) EP0753001B1 (is)
JP (1) JPH09508144A (is)
KR (1) KR100391401B1 (is)
CN (1) CN1056849C (is)
AP (1) AP614A (is)
AR (1) AR013815A1 (is)
AT (1) ATE184284T1 (is)
AU (1) AU704405B2 (is)
BG (1) BG62620B1 (is)
BR (1) BR9506473A (is)
CA (1) CA2179403A1 (is)
CO (1) CO4520226A1 (is)
CZ (1) CZ202796A3 (is)
DE (1) DE69512041T2 (is)
DK (1) DK0753001T3 (is)
EE (1) EE9600117A (is)
ES (1) ES2137549T3 (is)
FI (1) FI962773A (is)
GR (1) GR3031677T3 (is)
HK (1) HK1004222A1 (is)
HU (1) HU218611B (is)
IL (1) IL115905A0 (is)
IS (1) IS4352A (is)
MX (1) MX9602563A (is)
NO (1) NO307092B1 (is)
NZ (1) NZ296091A (is)
OA (1) OA10303A (is)
PE (1) PE49696A1 (is)
RU (1) RU2152398C1 (is)
SI (1) SI0753001T1 (is)
SK (1) SK88496A3 (is)
TW (1) TW321644B (is)
WO (1) WO1996014326A1 (is)
ZA (1) ZA959362B (is)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0901493A1 (en) * 1996-05-08 1999-03-17 Glaxo Wellcome S.A. Process for the preparation of an indacene compound
US6436395B1 (en) 1996-09-18 2002-08-20 Merck & Co., Inc. Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control
US6040463A (en) * 1996-10-07 2000-03-21 Merck & Co., Inc. Sordarin derivatives
US6096511A (en) * 1997-06-10 2000-08-01 Merck & Co., Inc. Protein elongation factor 2 as a target for antifungal and antiparasitic agents
NZ502763A (en) * 1997-08-22 2002-03-28 Merck & Co Inc 4-cyano-4-deformylsordarin derivatives
US5972996A (en) * 1997-08-22 1999-10-26 Merck & Co., Inc. 4-cyano-4-deformylsordarin derivatives
US5965612A (en) * 1997-08-22 1999-10-12 Merck & Co., Inc. 4-cyano-4-deformylsordaricin derivatives
US6136853A (en) * 1997-10-03 2000-10-24 Merck & Co., Inc. Sordarin derivatives
FI974385A0 (fi) * 1997-12-01 1997-12-01 Xyrofin Oy Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
US7070965B1 (en) * 1998-04-14 2006-07-04 Zhenhua Yang Small molecule anticancer compounds and related production process
MA26628A1 (fr) * 1998-05-11 2004-12-20 Glaxo Wellcome Sa Morpholino ethers
ATE255572T1 (de) 1998-10-26 2003-12-15 Merck & Co Inc Mikrobielle transformationsprodukte
EP1191948A2 (en) 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
EP1228049A1 (en) 1999-11-11 2002-08-07 Glaxo Wellcome S.A. Antifungal sordaricin derivatives
AU2001289063A1 (en) * 2000-09-15 2002-03-26 Bristol-Myers Squibb Company Novel thio derivatives of sordarin as antifungal agents
AU2002249935A1 (en) 2001-01-08 2002-08-19 Neorx Corporation Radioactively labelled conjugates of phosphonates
WO2003007878A2 (en) 2001-07-18 2003-01-30 Merck & Co., Inc. Antifungal agents of sordarin derivatives
WO2003051403A1 (en) 2001-12-13 2003-06-26 Dow Global Technologies Inc. Treatment of osteomyelitis with radiopharmaceuticals
AU2002351340A1 (en) * 2001-12-14 2003-06-30 Merck & Co., Inc. A novel sordarin derivative isolated from culture fermentations and functions as an antifungal agent
CA2511555A1 (en) * 2002-12-31 2004-07-22 Nektar Therapeutics Aerosolizable pharmaceutical formulation for fungal infection therapy
US9314524B2 (en) 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
US8419948B2 (en) * 2009-11-22 2013-04-16 United Laboratories International, Llc Wastewater treatment
WO2012033427A1 (ru) * 2010-09-08 2012-03-15 Dalin Mikhail Viktorovich Способ лечения микотических инфекций и препарат для его осуществления
RU2630403C2 (ru) * 2016-02-25 2017-09-07 Жанна Владимировна Вараткова Абразивная масса для изготовления инструмента с высокими номерами структуры

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH465771A (de) * 1965-12-06 1968-11-30 Sandoz Ag Verfahren zur Herstellung eines neuen Antibioticums
JPH0615555B2 (ja) * 1985-08-14 1994-03-02 三共株式会社 抗生物質ゾフイマリン
JP3189443B2 (ja) * 1992-11-20 2001-07-16 萬有製薬株式会社 抗真菌性物質be−31405
CA2265824C (en) * 1996-09-12 2004-11-09 Merck & Co., Inc. Antifungal combination therapy

Also Published As

Publication number Publication date
AU3980995A (en) 1996-05-31
HU9601865D0 (en) 1996-11-28
KR100391401B1 (ko) 2003-12-31
DE69512041T2 (de) 2000-02-03
SK88496A3 (en) 1997-04-09
AR013815A1 (es) 2001-01-31
RU2152398C1 (ru) 2000-07-10
IL115905A0 (en) 1996-01-31
FI962773A0 (fi) 1996-07-05
NO962856D0 (no) 1996-07-05
DK0753001T3 (da) 2000-05-08
EE9600117A (et) 1997-04-15
CN1143965A (zh) 1997-02-26
EP0753001A1 (en) 1997-01-15
JPH09508144A (ja) 1997-08-19
SI0753001T1 (en) 1999-12-31
CO4520226A1 (es) 1997-10-15
US5854280A (en) 1998-12-29
NZ296091A (en) 1998-06-26
NO962856L (no) 1996-09-05
FI962773A (fi) 1996-08-26
AU704405B2 (en) 1999-04-22
ZA959362B (en) 1996-05-08
ES2137549T3 (es) 1999-12-16
NO307092B1 (no) 2000-02-07
PE49696A1 (es) 1996-12-05
OA10303A (en) 1997-10-07
CN1056849C (zh) 2000-09-27
BR9506473A (pt) 1997-10-07
EP0753001B1 (en) 1999-09-08
TW321644B (is) 1997-12-01
AP614A (en) 1997-09-05
AP9600824A0 (en) 1996-07-31
CA2179403A1 (en) 1996-05-17
DE69512041D1 (de) 1999-10-14
HUT76292A (en) 1997-07-28
ATE184284T1 (de) 1999-09-15
US5952334A (en) 1999-09-14
MX9602563A (es) 1997-05-31
HK1004222A1 (en) 1998-11-20
BG100699A (bg) 1997-02-28
HU218611B (hu) 2000-10-28
GR3031677T3 (en) 2000-02-29
BG62620B1 (en) 2000-03-31
CZ202796A3 (en) 1997-02-12
WO1996014326A1 (en) 1996-05-17

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