IL98316A - 2-Tauril-5-Transformed-1,2, 4-Triazolo] A-1,5 [] 1,3,5 [Triazine-7 Amines and 7-Troaril-2-Transformed Pirazolo] A-1,5 [] 1, 3,5 [triazine-4 amines process to prepare - Google Patents
2-Tauril-5-Transformed-1,2, 4-Triazolo] A-1,5 [] 1,3,5 [Triazine-7 Amines and 7-Troaril-2-Transformed Pirazolo] A-1,5 [] 1, 3,5 [triazine-4 amines process to prepareInfo
- Publication number
- IL98316A IL98316A IL9831691A IL9831691A IL98316A IL 98316 A IL98316 A IL 98316A IL 9831691 A IL9831691 A IL 9831691A IL 9831691 A IL9831691 A IL 9831691A IL 98316 A IL98316 A IL 98316A
- Authority
- IL
- Israel
- Prior art keywords
- furyl
- amino
- alkyl
- formula
- triazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909011914A GB9011914D0 (en) | 1990-05-29 | 1990-05-29 | Heterocyclic compounds |
GB909011913A GB9011913D0 (en) | 1990-05-29 | 1990-05-29 | Azole derivatives |
GB919101379A GB9101379D0 (en) | 1991-01-22 | 1991-01-22 | Heterocyclic compounds |
GB919101380A GB9101380D0 (en) | 1991-01-22 | 1991-01-22 | Azole derivatives |
GB919104125A GB9104125D0 (en) | 1991-02-27 | 1991-02-27 | Azole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL98316A0 IL98316A0 (en) | 1992-06-21 |
IL98316A true IL98316A (en) | 1995-05-26 |
Family
ID=27516979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9831691A IL98316A (en) | 1990-05-29 | 1991-05-30 | 2-Tauril-5-Transformed-1,2, 4-Triazolo] A-1,5 [] 1,3,5 [Triazine-7 Amines and 7-Troaril-2-Transformed Pirazolo] A-1,5 [] 1, 3,5 [triazine-4 amines process to prepare |
Country Status (20)
Country | Link |
---|---|
US (1) | US5270311A (zh) |
EP (1) | EP0459702A1 (zh) |
JP (1) | JP2504879B2 (zh) |
KR (1) | KR910020012A (zh) |
CN (1) | CN1056879A (zh) |
AP (1) | AP248A (zh) |
AU (1) | AU642494B2 (zh) |
CA (1) | CA2043424A1 (zh) |
CS (1) | CS159591A3 (zh) |
FI (1) | FI912563A (zh) |
GB (1) | GB2244487B (zh) |
HU (1) | HUT61311A (zh) |
IE (1) | IE911818A1 (zh) |
IL (1) | IL98316A (zh) |
NO (1) | NO178401C (zh) |
NZ (1) | NZ238288A (zh) |
OA (1) | OA09358A (zh) |
PT (1) | PT97776A (zh) |
RO (1) | RO109542B1 (zh) |
YU (1) | YU47812B (zh) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5356894A (en) * | 1990-05-29 | 1994-10-18 | Rodney Peter W | Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist |
GB9226735D0 (en) * | 1992-12-22 | 1993-02-17 | Ici Plc | Azole derivatives |
EP0459702A1 (en) * | 1990-05-29 | 1991-12-04 | Zeneca Limited | Azole Derivatives |
GB9111130D0 (en) * | 1991-05-23 | 1991-07-17 | Ici Plc | Azole derivatives |
GB9111131D0 (en) * | 1991-05-23 | 1991-07-17 | Ici Plc | Heterocyclic compounds |
GB9125001D0 (en) * | 1991-11-25 | 1992-01-22 | Ici Plc | Heterocyclic compounds |
GB9125002D0 (en) * | 1991-11-25 | 1992-01-22 | Ici Plc | Azole derivatives |
GB9124968D0 (en) * | 1991-11-25 | 1992-01-22 | Ici Plc | Chemical process |
WO1995003806A1 (fr) * | 1993-07-27 | 1995-02-09 | Kyowa Hakko Kogyo Co., Ltd. | Remede contre la maladie de parkinson |
DE69426620T2 (de) * | 1993-09-06 | 2001-06-21 | Kyowa Hakko Kogyo Kk | Antidepressiva |
AU743910B2 (en) | 1997-03-24 | 2002-02-07 | Kyowa Hakko Kirin Co., Ltd. | {1,2,4}triazolo{1,5-c}pyrimidine derivatives |
US6060481A (en) * | 1998-05-28 | 2000-05-09 | The Penn State Research Foundation | Method for improving insulin sensitivity using an adenosine receptor antagonist |
CN1328560A (zh) * | 1998-09-22 | 2001-12-26 | 协和发酵工业株式会社 | [1,2,4]***并[1,5-c]嘧啶衍生物 |
JPWO2004029056A1 (ja) * | 2002-09-24 | 2006-01-26 | 協和醗酵工業株式会社 | [1,2,4]トリアゾロ[1,5−c]ピリミジン誘導体 |
US7329658B2 (en) * | 2003-02-06 | 2008-02-12 | Pfizer Inc | Cannabinoid receptor ligands and uses thereof |
WO2004092172A2 (en) * | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosin e receptor antagonists |
WO2004092170A2 (en) * | 2003-04-09 | 2004-10-28 | Biogen Idec Ma Inc. | Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists |
EP1615931A1 (en) | 2003-04-09 | 2006-01-18 | Biogen Idec MA Inc. | Triazolopyrazines and methods of making and using the same |
US7834014B2 (en) | 2003-04-09 | 2010-11-16 | Biogen Idec Ma Inc. | A2a adenosine receptor antagonists |
WO2004110454A1 (ja) * | 2003-06-13 | 2004-12-23 | Ishihara Sangyo Kaisha, Ltd. | アデノシンA2a受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物 |
US7652041B2 (en) | 2005-01-14 | 2010-01-26 | Millennium Pharmaceuticals, Inc. | Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity |
RU2015126797A (ru) | 2012-12-06 | 2017-01-12 | Сименс Акциенгезелльшафт | Система и способ введения тепла в геологическую формацию при помощи электромагнитной индукции |
CN106916073A (zh) * | 2017-01-20 | 2017-07-04 | 上海巧坤化工科技有限公司 | 一种大麦芽碱盐酸盐的合成方法 |
US20210032253A1 (en) * | 2018-02-06 | 2021-02-04 | Jiangsu Hengrui Medicine Co., Ltd. | Pyrazolo[1,5-a][1,3,5]triazine-2-amine derivative, preparation method therefor and medical use thereof |
CA3103068A1 (en) * | 2018-06-26 | 2020-01-02 | Zhejiang Vimgreen Pharmaceuticals, Ltd | Triazolotriazine derivatives as a2a receptor antagonists |
CN111051309B (zh) * | 2018-06-26 | 2023-05-26 | 浙江春禾医药科技有限公司 | 可用作a2a受体拮抗剂的***并三嗪衍生物 |
BE1026602B1 (fr) | 2018-09-27 | 2020-06-18 | Iteos Therapeutics S A | Inhibiteurs d’a2a ne penetrant pas dans le cerveau et methodes d’utilisation dans le traitement de cancers |
WO2020103939A1 (zh) * | 2018-11-22 | 2020-05-28 | 上海科技大学 | ***并环类化合物、其制备方法、中间体和应用 |
CN112608316B (zh) * | 2019-07-30 | 2022-10-21 | 厦门宝太生物科技股份有限公司 | 一种吡唑并三嗪类腺苷受体拮抗剂 |
CN114901665A (zh) * | 2019-12-26 | 2022-08-12 | 浙江春禾医药科技有限公司 | ***并三嗪衍生物在治疗疾病中的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3846423A (en) * | 1972-06-08 | 1974-11-05 | Icn Pharmaceuticals | Pyrazolo (1,5a) 1,3,5-triazines |
BE815405A (en) * | 1973-05-22 | 1974-11-22 | Pyrazolo(1,5-a)-s-triazines - and their salts, with bronchospasmolytic activity | |
US3995039A (en) * | 1975-05-27 | 1976-11-30 | Merck & Co., Inc. | Pyrazolo [1,5-a] [1,3,5] triazines |
GB1579932A (en) * | 1976-05-12 | 1980-11-26 | Ici Ltd | Herbicidal triazolotriazines |
GB2016002B (en) * | 1978-01-09 | 1982-05-06 | Aron Sa | Amino derivatives of pyrazolo(1,5-a)s triazine |
AU2192683A (en) * | 1982-12-30 | 1984-07-05 | Biomeasure Incorporated | Pyrazolo(1,5-alpha)-1,3,5-triazines |
CA1267143A (en) * | 1985-06-06 | 1990-03-27 | Sun H. Kim | Anti-arthritic 7-phenylpyrazole[1,5-a]-1,3,5- triazine derivatives |
US4824834A (en) * | 1986-10-31 | 1989-04-25 | Otsuka Pharmaceutical Company, Limited | Pyrazolotriazine compounds |
US4734413A (en) * | 1987-03-02 | 1988-03-29 | Riker Laboratories, Inc. | Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators |
EP0297651B1 (en) * | 1987-06-29 | 1993-11-03 | Duphar International Research B.V | Anellated indole derivatives |
US4970142A (en) * | 1989-02-16 | 1990-11-13 | Konica Corporation | Silver halide photographic light-sensitive material containing cyan coupler |
EP0459702A1 (en) * | 1990-05-29 | 1991-12-04 | Zeneca Limited | Azole Derivatives |
-
1991
- 1991-05-23 EP EP91304665A patent/EP0459702A1/en not_active Withdrawn
- 1991-05-23 GB GB9111132A patent/GB2244487B/en not_active Expired - Fee Related
- 1991-05-28 CS CS911595A patent/CS159591A3/cs unknown
- 1991-05-28 FI FI912563A patent/FI912563A/fi not_active Application Discontinuation
- 1991-05-28 AP APAP/P/1991/000266A patent/AP248A/en active
- 1991-05-28 AU AU77348/91A patent/AU642494B2/en not_active Ceased
- 1991-05-28 IE IE181891A patent/IE911818A1/en unknown
- 1991-05-28 NO NO912051A patent/NO178401C/no unknown
- 1991-05-28 YU YU94791A patent/YU47812B/sh unknown
- 1991-05-28 CA CA002043424A patent/CA2043424A1/en not_active Abandoned
- 1991-05-28 RO RO147639A patent/RO109542B1/ro unknown
- 1991-05-28 US US07/708,265 patent/US5270311A/en not_active Expired - Lifetime
- 1991-05-28 NZ NZ238288A patent/NZ238288A/xx unknown
- 1991-05-28 PT PT97776A patent/PT97776A/pt not_active Application Discontinuation
- 1991-05-28 KR KR1019910008926A patent/KR910020012A/ko not_active Application Discontinuation
- 1991-05-29 CN CN91103744A patent/CN1056879A/zh active Pending
- 1991-05-29 OA OA60010A patent/OA09358A/xx unknown
- 1991-05-29 JP JP3235332A patent/JP2504879B2/ja not_active Expired - Fee Related
- 1991-05-29 HU HU911789A patent/HUT61311A/hu unknown
- 1991-05-30 IL IL9831691A patent/IL98316A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO178401C (no) | 1996-03-20 |
KR910020012A (ko) | 1991-12-19 |
NO178401B (no) | 1995-12-11 |
GB2244487A (en) | 1991-12-04 |
FI912563A (fi) | 1991-11-30 |
YU47812B (sr) | 1996-01-09 |
NZ238288A (en) | 1993-07-27 |
HUT61311A (en) | 1992-12-28 |
JPH0597855A (ja) | 1993-04-20 |
GB2244487B (en) | 1994-02-02 |
FI912563A0 (fi) | 1991-05-28 |
AP9100266A0 (en) | 1991-07-31 |
RO109542B1 (ro) | 1995-03-30 |
AU7734891A (en) | 1991-12-05 |
IE911818A1 (en) | 1991-12-04 |
AU642494B2 (en) | 1993-10-21 |
HU911789D0 (en) | 1991-12-30 |
US5270311A (en) | 1993-12-14 |
GB9111132D0 (en) | 1991-07-17 |
AP248A (en) | 1993-03-16 |
YU94791A (sh) | 1994-06-24 |
IL98316A0 (en) | 1992-06-21 |
EP0459702A1 (en) | 1991-12-04 |
NO912051D0 (no) | 1991-05-28 |
OA09358A (fr) | 1992-09-15 |
CA2043424A1 (en) | 1991-11-30 |
CS159591A3 (en) | 1992-01-15 |
JP2504879B2 (ja) | 1996-06-05 |
CN1056879A (zh) | 1991-12-11 |
NO912051L (no) | 1991-12-02 |
PT97776A (pt) | 1992-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |