IL97446A - Medicinal product for the improvement of down-regulation of autoimmune diseases - Google Patents

Medicinal product for the improvement of down-regulation of autoimmune diseases

Info

Publication number
IL97446A
IL97446A IL9744691A IL9744691A IL97446A IL 97446 A IL97446 A IL 97446A IL 9744691 A IL9744691 A IL 9744691A IL 9744691 A IL9744691 A IL 9744691A IL 97446 A IL97446 A IL 97446A
Authority
IL
Israel
Prior art keywords
suppressive
autoantigens
disease
agent
pharmaceutical composition
Prior art date
Application number
IL9744691A
Other languages
English (en)
Hebrew (he)
Other versions
IL97446A0 (en
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Publication of IL97446A0 publication Critical patent/IL97446A0/xx
Publication of IL97446A publication Critical patent/IL97446A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL9744691A 1990-03-02 1991-03-05 Medicinal product for the improvement of down-regulation of autoimmune diseases IL97446A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48773290A 1990-03-02 1990-03-02

Publications (2)

Publication Number Publication Date
IL97446A0 IL97446A0 (en) 1992-06-21
IL97446A true IL97446A (en) 1996-03-31

Family

ID=23936898

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9744691A IL97446A (en) 1990-03-02 1991-03-05 Medicinal product for the improvement of down-regulation of autoimmune diseases

Country Status (13)

Country Link
EP (2) EP0782859A1 (hu)
JP (1) JPH05508621A (hu)
AT (1) ATE157257T1 (hu)
AU (1) AU651097B2 (hu)
BR (1) BR9106114A (hu)
CA (1) CA2077340A1 (hu)
DE (1) DE69127470T2 (hu)
DK (1) DK0594607T3 (hu)
ES (1) ES2107459T3 (hu)
HU (2) HUT61896A (hu)
IL (1) IL97446A (hu)
NO (1) NO923395L (hu)
WO (1) WO1991012816A1 (hu)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6645504B1 (en) 1987-06-24 2003-11-11 Autoimmune Inc. Bystander suppression of type I diabetes by oral administration of glucagon
US5268454A (en) 1991-02-08 1993-12-07 La Jolla Pharmaceutical Company Composition for inducing humoral anergy to an immunogen comprising a t cell epitope-deficient analog of the immunogen conjugated to a nonimmunogenic carrier
IL99699A (en) 1990-10-10 2002-04-21 Autoimmune Inc Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes
JP2635444B2 (ja) * 1990-10-15 1997-07-30 オートイミューン インク 自己抗体の経口投与による自己免疫性疾患の治療
DK0627933T3 (da) * 1992-02-28 2003-03-24 Autoimmune Inc Bystander-suppression af autoimmune sygdomme
US5891435A (en) * 1993-04-16 1999-04-06 Research Corporation Technologies, Inc. Methods and compositions for delaying or preventing the onset of autoimmune disease
CA2164326A1 (en) * 1993-06-02 1994-12-08 Wayne Robert Thomas Cryptic peptides for use in inducing immunologic tolerance
GB9319429D0 (en) 1993-09-21 1993-11-03 London Health Ass Methods and products for controlling immune responses in mammals
WO1996012737A2 (en) * 1994-10-25 1996-05-02 Immulogic Pharmaceutical Corporation Compositions and treatment for multiple sclerosis
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
EP1172376A1 (en) 1994-11-18 2002-01-16 Neurocrine Biosciences, Inc. Peptide analogues at position 91 of human myelin basic protein for treatment of multiple sclerosis
US6329499B1 (en) 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
EP0831877B1 (en) * 1995-06-07 2004-10-27 Telik, Inc. Metabolic effects of certain glutathione analogs
US6488933B2 (en) 1995-07-05 2002-12-03 Yeda Research And Development Co. Ltd. Preparations for the treatment of T cell mediated diseases
ES2320939T3 (es) * 1996-01-05 2009-05-29 Autoimmune, Inc. Metodo para la preparacion de colageno de tipo ii.
US5849886A (en) * 1996-07-10 1998-12-15 Oy Aboatech Ab Extraction of myelin basic protein
US6211160B1 (en) * 1996-09-06 2001-04-03 The Trustees Of The University Of Pennsylvania Method for tolerizing a mammalian patient to administration of gene therapy virus vectors
JP4086928B2 (ja) * 1997-02-13 2008-05-14 大日本住友製薬株式会社 タイプ2ヘルパーt細胞型サイトカイン産生選択的抑制剤
US7097845B2 (en) 1997-04-23 2006-08-29 Jacob Sten Petersen Combinations of antigen and mucosal binding component for inducing specific immunological tolerance
US6750324B1 (en) 1997-12-02 2004-06-15 Neuralab Limited Humanized and chimeric N-terminal amyloid beta-antibodies
US6710226B1 (en) 1997-12-02 2004-03-23 Neuralab Limited Transgenic mouse assay to determine the effect of Aβ antibodies and Aβ Fragments on alzheimer's disease characteristics
TWI239847B (en) 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
US6743427B1 (en) 1997-12-02 2004-06-01 Neuralab Limited Prevention and treatment of amyloidogenic disease
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US6923964B1 (en) 1997-12-02 2005-08-02 Neuralab Limited Active immunization of AScr for prion disorders
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US6913745B1 (en) 1997-12-02 2005-07-05 Neuralab Limited Passive immunization of Alzheimer's disease
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
US6787637B1 (en) 1999-05-28 2004-09-07 Neuralab Limited N-Terminal amyloid-β antibodies
UA81216C2 (en) 1999-06-01 2007-12-25 Prevention and treatment of amyloid disease
US7897575B2 (en) 2000-05-24 2011-03-01 The United States Of America As Represented By The Department Of Health And Human Services Treatment and prevention of vascular dementia
JP4986361B2 (ja) 2000-05-24 2012-07-25 ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ E−セレクチンに対する寛容誘導による脳卒中防止法
US7700751B2 (en) 2000-12-06 2010-04-20 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize β-amyloid peptide
MY139983A (en) 2002-03-12 2009-11-30 Janssen Alzheimer Immunotherap Humanized antibodies that recognize beta amyloid peptide
PE20050627A1 (es) 2003-05-30 2005-08-10 Wyeth Corp Anticuerpos humanizados que reconocen el peptido beta amiloideo
JP2008523815A (ja) 2004-12-15 2008-07-10 エラン ファーマ インターナショナル リミテッド 認知の改善における使用のためのヒト化アミロイドβ抗体
US8784810B2 (en) 2006-04-18 2014-07-22 Janssen Alzheimer Immunotherapy Treatment of amyloidogenic diseases
US8003097B2 (en) 2007-04-18 2011-08-23 Janssen Alzheimer Immunotherapy Treatment of cerebral amyloid angiopathy
DK2182983T3 (da) 2007-07-27 2014-07-14 Janssen Alzheimer Immunotherap Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
US9067981B1 (en) 2008-10-30 2015-06-30 Janssen Sciences Ireland Uc Hybrid amyloid-beta antibodies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309406A (en) 1979-07-10 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4309404A (en) 1979-08-09 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4556552A (en) 1983-09-19 1985-12-03 Colorcon, Inc. Enteric film-coating compositions
US4704295A (en) 1983-09-19 1987-11-03 Colorcon, Inc. Enteric film-coating compositions
JPS60149386A (ja) * 1984-01-17 1985-08-06 Dainippon Pharmaceut Co Ltd インタ−ロイキン1をコ−ドする伝令リボ核酸及びその調製法
US4695459A (en) * 1984-12-26 1987-09-22 The Board Of Trustees Of Leland Stanford Junior University Method of treating autoimmune diseases that are mediated by Leu3/CD4 phenotype T cells
DE19848246A1 (de) 1998-10-20 2000-04-27 Krauss Maffei Kunststofftech Thermoplastteil mit eingespritzter Elastomerdichtung
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient

Also Published As

Publication number Publication date
NO923395D0 (no) 1992-08-31
EP0594607A4 (en) 1993-04-20
AU651097B2 (en) 1994-07-14
DK0594607T3 (da) 1998-04-14
HU210813A9 (en) 1995-08-28
IL97446A0 (en) 1992-06-21
EP0594607A1 (en) 1994-05-04
EP0594607B1 (en) 1997-08-27
DE69127470T2 (de) 1998-02-19
NO923395L (no) 1992-08-31
BR9106114A (pt) 1993-03-09
JPH05508621A (ja) 1993-12-02
ES2107459T3 (es) 1997-12-01
WO1991012816A1 (en) 1991-09-05
EP0782859A1 (en) 1997-07-09
HUT61896A (en) 1993-03-29
DE69127470D1 (de) 1997-10-02
AU7578991A (en) 1991-09-18
HU9202808D0 (en) 1992-12-28
CA2077340A1 (en) 1991-09-03
ATE157257T1 (de) 1997-09-15

Similar Documents

Publication Publication Date Title
EP0594607B1 (en) Enhancement of the down-regulation of autoimmune diseases by oral or enteral administration of autoantigens
EP0359783B2 (en) Treatment of autoimmune diseases by oral administration of autoantigens
KR0185747B1 (ko) 자기항원의 에어로졸 투여에 의한 자기면역질환의 개선된 치료방법
JP3712260B2 (ja) 自己免疫疾患のバイスタンダー抑制
US5571500A (en) Treatment of autoimmune diseases through administration by inhalation of autoantigens
US5641474A (en) Prevention of autoimmune diseases by aerosol administration of autoantigens
EP0553291B1 (en) Treatment of autoimmune diseases by oral administration of autoantigens
US5571499A (en) Treatment of autoimmune diseases by aerosol administration of autoantigens
US5645820A (en) Treatment of autoimmune diseases by aerosol administration of autoantigens
US5720955A (en) Method of treating rheumatoid arthritis with soluble collagen
WO1994007520A9 (en) Method of treating rheumatoid arthritis with type ii collagen
US5961977A (en) Method of treating or preventing autoimmune uveoretinitis in mammals
JPH09511990A (ja) 経口寛容および/またはTh2増強サイトカインを用いた自己免疫疾患の治療
EP0977586B1 (en) Combinations of antigen and mucosal binding component for inducing specific immunological tolerance
JPH09511745A (ja) 経口寛容および/またはタイプiインターフェロンを用いた自己免疫疾患の治療

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees