IL68909A - 5-aroyl-6-alkylthio-1,2-dihydro-3h-pyrrolo(1,2 a)pyrrole-1-carboxylic acids and derivatives thereof;their production and pharmaceutical compositions containing them - Google Patents

5-aroyl-6-alkylthio-1,2-dihydro-3h-pyrrolo(1,2 a)pyrrole-1-carboxylic acids and derivatives thereof;their production and pharmaceutical compositions containing them

Info

Publication number: IL68909A
Authority: IL; Israel
Prior art keywords: sub; alkylthio; aroyl; pyrrolo; pyrrole
Prior art date: 1982-06-08

Application number

IL68909A

Other languages

English (en)

Other versions

IL68909A0 (en

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-08

Filing date

1983-06-07

Publication date

1987-02-27

1983-06-07 Application filed by Syntex Inc filed Critical Syntex Inc

1983-10-31 Publication of IL68909A0 publication Critical patent/IL68909A0/xx

1986-03-14 Priority to IL78159A priority Critical patent/IL78159A0/xx

1987-02-27 Publication of IL68909A publication Critical patent/IL68909A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)

IL68909A 1982-06-08 1983-06-07 5-aroyl-6-alkylthio-1,2-dihydro-3h-pyrrolo(1,2 a)pyrrole-1-carboxylic acids and derivatives thereof;their production and pharmaceutical compositions containing them IL68909A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL78159A IL78159A0 (en)	1982-06-08	1986-03-14	5-aroyl-6-alkylthio-,-alkylsulfinyl-and-alkylsulfonyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carbonitriles

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/386,174 US4612325A (en)	1982-06-08	1982-06-08	5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories

Publications (2)

Publication Number	Publication Date
IL68909A0 IL68909A0 (en)	1983-10-31
IL68909A true IL68909A (en)	1987-02-27

Family

ID=23524483

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL68909A IL68909A (en)	1982-06-08	1983-06-07	5-aroyl-6-alkylthio-1,2-dihydro-3h-pyrrolo(1,2 a)pyrrole-1-carboxylic acids and derivatives thereof;their production and pharmaceutical compositions containing them

Country Status (16)

Country	Link
US (1)	US4612325A (ko)
EP (1)	EP0096583B1 (ko)
JP (1)	JPS595190A (ko)
KR (1)	KR880000393B1 (ko)
AT (1)	ATE29497T1 (ko)
AU (1)	AU556295B2 (ko)
CA (1)	CA1200244A (ko)
DE (1)	DE3373474D1 (ko)
DK (1)	DK260483A (ko)
ES (4)	ES523063A0 (ko)
FI (1)	FI77245C (ko)
HU (1)	HU190106B (ko)
IL (1)	IL68909A (ko)
NO (1)	NO162386B (ko)
NZ (1)	NZ204487A (ko)
ZA (1)	ZA834137B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4560699A (en) *	1983-01-17	1985-12-24	Syntex (U.S.A.) Inc.	5-(4-Vinylbenzoyl)-1,2-dihydro-3H-pyrrolo-[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof and use as analgesics and anti-inflammatories
JPH0739418B2 (ja) *	1987-09-10	1995-05-01	久光製薬株式会社	新規な３−アロイル−６，７−ジヒドロ−５Ｈ−ピロロ〔１，２−ｃ〕イミダゾール−７−カルボン酸誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4097579A (en) *	1977-03-31	1978-06-27	Syntex (U.S.A.) Inc.	5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4232038A (en) *	1979-08-31	1980-11-04	Syntex (U.S.A.) Inc.	5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids
US4344943A (en) *	1980-06-09	1982-08-17	Syntex (U.S.A.) Inc.	6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents

1982
- 1982-06-08 US US06/386,174 patent/US4612325A/en not_active Expired - Fee Related
1983
- 1983-06-07 JP JP58102535A patent/JPS595190A/ja active Pending
- 1983-06-07 KR KR1019830002524A patent/KR880000393B1/ko not_active IP Right Cessation
- 1983-06-07 ZA ZA834137A patent/ZA834137B/xx unknown
- 1983-06-07 NZ NZ204487A patent/NZ204487A/xx unknown
- 1983-06-07 DE DE8383303285T patent/DE3373474D1/de not_active Expired
- 1983-06-07 ES ES523063A patent/ES523063A0/es active Granted
- 1983-06-07 CA CA000429837A patent/CA1200244A/en not_active Expired
- 1983-06-07 EP EP83303285A patent/EP0096583B1/en not_active Expired
- 1983-06-07 DK DK260483A patent/DK260483A/da not_active Application Discontinuation
- 1983-06-07 AU AU15464/83A patent/AU556295B2/en not_active Ceased
- 1983-06-07 FI FI832045A patent/FI77245C/fi not_active IP Right Cessation
- 1983-06-07 AT AT83303285T patent/ATE29497T1/de not_active IP Right Cessation
- 1983-06-07 IL IL68909A patent/IL68909A/xx unknown
- 1983-06-07 HU HU832030A patent/HU190106B/hu not_active IP Right Cessation
- 1983-06-07 NO NO832053A patent/NO162386B/no unknown
1984
- 1984-11-16 ES ES537694A patent/ES8600294A1/es not_active Expired
- 1984-11-16 ES ES537696A patent/ES8600296A1/es not_active Expired
- 1984-11-16 ES ES537695A patent/ES8600295A1/es not_active Expired

Also Published As

Publication number	Publication date
NZ204487A (en)	1986-06-11
FI77245C (fi)	1989-02-10
NO832053L (no)	1983-12-09
CA1200244A (en)	1986-02-04
ES537694A0 (es)	1985-10-16
AU1546483A (en)	1983-12-15
IL68909A0 (en)	1983-10-31
FI832045L (fi)	1983-12-09
EP0096583A2 (en)	1983-12-21
ES8600294A1 (es)	1985-10-16
US4612325A (en)	1986-09-16
NO162386B (no)	1989-09-11
DK260483D0 (da)	1983-06-07
FI832045A0 (fi)	1983-06-07
KR880000393B1 (ko)	1988-03-21
HU190106B (en)	1986-08-28
ES537696A0 (es)	1985-10-16
ATE29497T1 (de)	1987-09-15
JPS595190A (ja)	1984-01-12
ES537695A0 (es)	1985-10-16
ES8600296A1 (es)	1985-10-16
ZA834137B (en)	1985-01-30
ES8502999A1 (es)	1985-02-16
ES8600295A1 (es)	1985-10-16
FI77245B (fi)	1988-10-31
DK260483A (da)	1983-12-09
DE3373474D1 (en)	1987-10-15
AU556295B2 (en)	1986-10-30
ES523063A0 (es)	1985-02-16
EP0096583A3 (en)	1985-05-02
KR840005144A (ko)	1984-11-03
EP0096583B1 (en)	1987-09-09

Publication	Publication Date	Title
CA1260471C (ko)	1989-09-26
JPS56142259A (en)	1981-11-06	Beta-lactam compound and its preparation
AU671305B2 (en)	1996-08-22	Pyrazolo(4,3-c)pyridines, a process for their preparation and their use as serotonin reuptake inhibitors
TW254935B (ko)	1995-08-21
HU9203977D0 (en)	1993-04-28	Method for producing heteroaryl-8-aza-bicyclo-/3.2.1/octanes and pharmaceutical preparatives containing them
IL68909A (en)	1987-02-27	5-aroyl-6-alkylthio-1,2-dihydro-3h-pyrrolo(1,2 a)pyrrole-1-carboxylic acids and derivatives thereof;their production and pharmaceutical compositions containing them
DE3666588D1 (en)	1989-11-30	Spiroûbenzofuran-2(3h), 1'cycloheptane¨s, a process and intermediates for their preparation and their use as medicaments
FI894125A (fi)	1990-03-03	Analogiamenetelmä terapeuttisesti käyttökelpoisen 3-piperidinyyli-indatsolin valmistamiseksi
ES514783A0 (es)	1984-02-01	Un procedimiento para preparar acido 1,4-dimetil-i-(1-metil-5-metil-tiopirrol-2-oil) pirrol-2-acetico y sus analogos,dotados de propiedades antiinflamatorias.
EP0167922A3 (en)	1987-01-21	Pyrrolo û1,2-b¨ û1,2,5¨ triazepines, a process and intermediates for their preparation and their use as medicaments
HU893309D0 (en)	1991-05-28	Process for producing antagonists of alpha-adrenergic receptor and pharmaceutical preparatives containing these compounds
JPS6470488A (en)	1989-03-15	Novel 3-aroyl-6,7-dihydro-5h-pyrrolo(1,2-c)imidazole-7-carboxylic acid derivative
ES8600760A1 (es)	1985-11-01	Procedimiento para preparar 2-((3, 4-metilendioxi)-fenetil)-5-((3-carboxamido-4-hidroxi)- -hidroxibencil)-pirrolidina
PT84005A (en)	1987-01-01	6h-isoxazol]3,4-d"pyrazolo]3,4-b"pyridines a process and intermediates for their preparation and their use as medicaments