IL53407A0 - Enzymatic cleavage of alpha-amino-alpha(rho-acetoxyphenylacetamido)desacetoxycephalosporanic acid - Google Patents

Enzymatic cleavage of alpha-amino-alpha(rho-acetoxyphenylacetamido)desacetoxycephalosporanic acid

Info

Publication number: IL53407A0
Authority: IL; Israel
Prior art keywords: alpha; acetoxyphenylacetamido; rho; amino; enzymatic cleavage
Prior art date: 1974-06-05

Application number

IL53407A

Other languages

English (en)

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-05

Filing date

1977-11-16

Publication date

1978-01-31

1977-11-16 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1978-01-31 Publication of IL53407A0 publication Critical patent/IL53407A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Cephalosporin Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

IL53407A 1974-06-05 1977-11-16 Enzymatic cleavage of alpha-amino-alpha(rho-acetoxyphenylacetamido)desacetoxycephalosporanic acid IL53407A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2484874A GB1476981A (en)	1974-06-05	1974-06-05	Substituted penicillanic acids

Publications (1)

Publication Number	Publication Date
IL53407A0 true IL53407A0 (en)	1978-01-31

Family

ID=10218206

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL47360A IL47360A (en)	1974-06-05	1975-05-26	-amino- and -formyl- -(p-acycloxyphenyl) acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IL53407A IL53407A0 (en)	1974-06-05	1977-11-16	Enzymatic cleavage of alpha-amino-alpha(rho-acetoxyphenylacetamido)desacetoxycephalosporanic acid

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IL47360A IL47360A (en)	1974-06-05	1975-05-26	-amino- and -formyl- -(p-acycloxyphenyl) acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (25)

Country	Link
US (1)	US4012382A (xx)
JP (4)	JPS6150955B2 (xx)
AR (2)	AR210855A1 (xx)
AT (1)	AT339480B (xx)
AU (1)	AU496892B2 (xx)
BE (2)	BE828686A (xx)
CA (1)	CA1051799A (xx)
CH (1)	CH617202A5 (xx)
CS (1)	CS189709B2 (xx)
DD (3)	DD122094A5 (xx)
DE (1)	DE2524320C2 (xx)
DK (2)	DK155943C (xx)
ES (2)	ES438179A1 (xx)
FI (1)	FI60867C (xx)
FR (2)	FR2273546A1 (xx)
GB (1)	GB1476981A (xx)
HU (3)	HU174102B (xx)
IE (1)	IE43052B1 (xx)
IL (2)	IL47360A (xx)
IN (1)	IN142267B (xx)
LU (1)	LU72618A1 (xx)
SE (2)	SE426171B (xx)
SU (3)	SU828968A3 (xx)
YU (3)	YU40121B (xx)
ZA (2)	ZA752504B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4286089A (en) *	1974-12-27	1981-08-25	Smithkline Corporation	7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US3989694A (en) *	1974-12-27	1976-11-02	Smithkline Corporation	7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
NO760358L (xx) *	1975-02-04	1976-08-05	Fujisawa Pharmaceutical Co
US4093723A (en) *	1976-05-19	1978-06-06	Smithkline Corporation	7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4111981A (en) *	1975-12-15	1978-09-05	Smithkline Corporation	Intermediates for preparing substituted phenylglycylcephalosporins
IL51651A0 (en) *	1976-03-19	1977-05-31	Merck Patent Gmbh	Cephem derivatives and processes for their preparation
GB1532682A (en) *	1976-04-27	1978-11-22	Bristol Myers Co	Process for the preparation of cephadroxil
US4034092A (en) *	1976-05-03	1977-07-05	Smithkline Corporation	7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins
AU2550077A (en) *	1976-06-14	1978-11-30	Merck Patent Gmbh	Penicillins and cephalosporins
JPS5346995A (en) *	1976-10-12	1978-04-27	Sangyo Kagaku Kenkyu Kyokai	Antibacterial agents
US4160863A (en)	1977-04-07	1979-07-10	Bristol-Myers Company	Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US4236002A (en) *	1977-12-23	1980-11-25	Yeda Research & Development Co., Ltd.	Cephalosporin derivatives
DE2852067A1 (de) *	1978-11-29	1980-06-12	Schering Ag	Verfahren zur herstellung von 5-mercapto-1,2,3-triazolen
DE2920939A1 (de) *	1979-05-21	1980-11-27	Schering Ag	Verfahren zur herstellung von 5-mercapto-1,2,3-triazolen
JPS58122471U (ja) *	1982-02-15	1983-08-20	株式会社ほくさん	クライオスタツトのスペ−サ−
JPS59152757U (ja) *	1983-03-31	1984-10-13	株式会社ほくさん	クライオスタツトのスペ−サ
JPS6019776A (ja) *	1983-07-12	1985-01-31	Ube Ind Ltd	安定化された５―メルカプト―１，２，３―チアジアゾール類組成物
JPS6041271A (ja) *	1984-07-09	1985-03-04	Hitachi Ltd	超電導装置
GB9216759D0 (en) *	1992-08-07	1992-09-23	Finpael Spa	Process for the production of 7-amino thiazolyl cephalosporins
US6550343B2 (en) *	2001-07-13	2003-04-22	Westinghouse Air Brake Technologies Corporation	Method and apparatus for testing shear strength of rubber bonded to metal insert

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1461320A (fr)	1961-04-10	1966-02-25	Nat Res Dev	Procédé de production de dérivés de désacétylation de la céphalosporine c
GB1082943A (en) *	1963-03-27	1967-09-13	Glaxo Lab Ltd	Derivatives of 7-aminocephalosporanic acid
GB1082962A (en) *	1963-05-28	1967-09-13	Glaxo Lab Ltd	Derivatives of 7-aminocephalosporanic acid
DE1445639B2 (de)	1963-11-19	1976-09-09	Ciba-Geigy Ag, Basel (Schweiz)	Verfahren zur herstellung von desacetyl-7-aminocephalosporansaeure
FR1460131A (fr) *	1964-10-30	1966-06-17	Glaxo Lab Ltd	Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés
US3453263A (en) *	1965-03-01	1969-07-01	American Home Prod	Method of preparing penicillins
GB1241656A (en) *	1967-08-21	1971-08-04	Glaxo Lab Ltd	Improvements in or relating to cephalosporin compounds
US3489750A (en) *	1967-09-05	1970-01-13	Bristol Myers Co	7-amino-cephalosporanic and decephalosporanic acid derivatives
GB1277415A (en) *	1968-06-14	1972-06-14	Glaxo Lab Ltd	Improvements in or relating to cephalosporin derivatives
US3579514A (en) *	1969-01-24	1971-05-18	Bristol Myers Co	7 - (alpha-(3 - guanyl-1-ureido)aryl-acetamido) cephalosporanic acids and derivatives thereof
US3641021A (en) *	1969-04-18	1972-02-08	Lilly Co Eli	3 7-(ring-substituted) cephalosporin compounds
GB1326531A (en) *	1969-08-26	1973-08-15	Glaxo Lab Ltd	Cephalosporin compounds
US3753977A (en) *	1969-11-27	1973-08-21	Ciba Geigy Corp	Process for the cleavage of esters of 7-amino-cephem-4-carboxylic acid compounds
GB1342241A (en) *	1970-01-23	1974-01-03	Glaxo Lab Ltd	Cephalosporin compounds
GB1334382A (en) *	1970-03-26	1973-10-17	Glaxo Lab Ltd	Antibiotics
US3701775A (en) *	1970-11-25	1972-10-31	Smith Kline French Lab	Esters of mandeloylaminocephalosporanic acids
US3867380A (en) *	1971-02-18	1975-02-18	Smithkline Corp	3-Heterocyclic thiomethylcephalosporins
US3855213A (en) *	1971-02-18	1974-12-17	Smith Kline French Lab	3-heterocyclic thiomethyl-cephalosporins
IL38099A (en) *	1970-12-17	1976-01-30	Smith Kline French Lab	3-heterocyclyl thiomethylcephalosporins
GB1319173A (en) *	1971-06-17	1973-06-06	Fujisawa Pharmaceutical Co	7-acylated-3-substituted cephalosporin compounds
JPS5442997B2 (xx) *	1971-10-18	1979-12-17
JPS4868588A (xx) *	1971-12-22	1973-09-18
US3813388A (en) *	1972-01-31	1974-05-28	L Crast	7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(2-methyl-1,2,3-triazole-4-yl)thiomethyl)-3-cephem-4-carboxylic acids
CA1076560A (en) *	1972-06-14	1980-04-29	Smith Kline And French Canada Ltd.	3-heterocyclic thiomethylcephalosporins
US3943129A (en) *	1972-11-14	1976-03-09	Smithkline Corporation	7-Amino-3-(1,3,4-thiadiazolinylthio-methyl) cephalosporins
US3868369A (en) *	1972-11-14	1975-02-25	Smithkline Corp	3-heterocyclicthiomethylcephalosporins
US3953439A (en) *	1973-08-01	1976-04-27	Smithkline Corporation	Substituted phenylglycylcephalosporins
US3931160A (en) *	1974-05-15	1976-01-06	Smithkline Corporation	α-Amino-α-(acylamidophenyl)acetamidocephalosporins

1974
- 1974-06-05 GB GB2484874A patent/GB1476981A/en not_active Expired
1975
- 1975-04-18 ZA ZA00752504A patent/ZA752504B/xx unknown
- 1975-05-02 BE BE156029A patent/BE828686A/xx not_active IP Right Cessation
- 1975-05-14 HU HU75BI515A patent/HU174102B/hu unknown
- 1975-05-24 IN IN1053/CAL/75A patent/IN142267B/en unknown
- 1975-05-26 ZA ZA00753387A patent/ZA753387B/xx unknown
- 1975-05-26 AU AU81529/75A patent/AU496892B2/en not_active Expired
- 1975-05-26 IL IL47360A patent/IL47360A/xx unknown
- 1975-05-27 US US05/581,054 patent/US4012382A/en not_active Expired - Lifetime
- 1975-05-28 DK DK236275A patent/DK155943C/da not_active IP Right Cessation
- 1975-05-30 LU LU72618A patent/LU72618A1/xx unknown
- 1975-05-30 FI FI751595A patent/FI60867C/fi not_active IP Right Cessation
- 1975-05-30 BE BE156933A patent/BE829758A/xx not_active IP Right Cessation
- 1975-06-02 DE DE2524320A patent/DE2524320C2/de not_active Expired
- 1975-06-02 CA CA228,229A patent/CA1051799A/en not_active Expired
- 1975-06-02 HU HU75BI536A patent/HU173040B/hu unknown
- 1975-06-02 HU HU75BI00000516A patent/HU172448B/hu unknown
- 1975-06-02 SE SE7506294A patent/SE426171B/xx not_active IP Right Cessation
- 1975-06-03 ES ES438179A patent/ES438179A1/es not_active Expired
- 1975-06-03 DD DD186424A patent/DD122094A5/xx unknown
- 1975-06-03 DD DD7500195744A patent/DD127730A5/xx unknown
- 1975-06-03 DD DD7500195747A patent/DD127731A5/xx unknown
- 1975-06-04 IE IE1245/75A patent/IE43052B1/en unknown
- 1975-06-04 FR FR7517489A patent/FR2273546A1/fr not_active Withdrawn
- 1975-06-04 YU YU1437/75A patent/YU40121B/xx unknown
- 1975-06-04 CS CS753917A patent/CS189709B2/cs unknown
- 1975-06-04 SU SU752143253A patent/SU828968A3/ru active
- 1975-06-05 CH CH727975A patent/CH617202A5/de not_active IP Right Cessation
- 1975-06-05 AT AT429375A patent/AT339480B/de active
- 1975-06-05 JP JP50067119A patent/JPS6150955B2/ja not_active Expired
- 1975-06-08 AR AR259056A patent/AR210855A1/es active
- 1975-11-18 SU SU752189951A patent/SU654171A3/ru active
- 1975-11-18 SU SU752189817A patent/SU629880A3/ru active
1976
- 1976-01-01 AR AR262382A patent/AR208111A1/es active
- 1976-01-20 FR FR7601467A patent/FR2296639A1/fr active Granted
1977
- 1977-01-12 ES ES454964A patent/ES454964A1/es not_active Expired
- 1977-11-16 IL IL53407A patent/IL53407A0/xx not_active IP Right Cessation
1978
- 1978-04-05 SE SE7803860A patent/SE434840B/sv not_active IP Right Cessation
1981
- 1981-08-18 YU YU1997/81A patent/YU45103B/xx unknown
- 1981-08-18 YU YU1998/81A patent/YU43130B/xx unknown
1984
- 1984-12-21 JP JP59268756A patent/JPS60166688A/ja active Granted
1985
- 1985-04-19 JP JP60082717A patent/JPS60259198A/ja active Granted
- 1985-04-19 JP JP60082716A patent/JPS60260585A/ja active Pending
1988
- 1988-10-06 DK DK559588A patent/DK156272C/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA1051799A (en)	1979-04-03
DK156272C (da)	1989-12-18
SU654171A3 (ru)	1979-03-25
SE7803860L (sv)	1978-04-05
DD127730A5 (de)	1977-10-12
GB1476981A (en)	1977-06-16
DK156272B (da)	1989-07-24
SE426171B (sv)	1982-12-13
FI60867C (fi)	1982-04-13
DK155943C (da)	1989-10-16
YU199781A (en)	1983-12-31
ATA429375A (de)	1977-02-15
IE43052B1 (en)	1980-12-17
ES438179A1 (es)	1977-05-16
JPS6150955B2 (xx)	1986-11-06
AU8152975A (en)	1976-12-02
YU43130B (en)	1989-04-30
AT339480B (de)	1977-10-25
DK236275A (da)	1975-12-06
LU72618A1 (xx)	1976-03-17
FI751595A (xx)	1975-12-06
FR2273546A1 (fr)	1976-01-02
SU629880A3 (ru)	1978-10-25
IL47360A0 (en)	1975-11-25
FR2296639B1 (xx)	1978-10-06
AU496892B2 (en)	1978-11-09
IL47360A (en)	1978-12-17
HU173040B (hu)	1979-02-28
YU143775A (en)	1982-02-28
SU828968A3 (ru)	1981-05-07
DE2524320C2 (de)	1985-01-24
DK155943B (da)	1989-06-05
SE434840B (sv)	1984-08-20
JPS60166688A (ja)	1985-08-29
ZA753387B (en)	1976-04-28
YU40121B (en)	1985-08-31
HU172448B (hu)	1978-09-28
DE2524320A1 (de)	1975-12-18
JPS6260079B2 (xx)	1987-12-14
YU199881A (en)	1983-12-31
SE7506294L (sv)	1975-12-08
JPS60260585A (ja)	1985-12-23
JPS60259198A (ja)	1985-12-21
DK559588D0 (da)	1988-10-06
YU45103B (en)	1992-03-10
BE828686A (fr)	1975-09-01
BE829758A (fr)	1975-12-01
AR208111A1 (es)	1976-11-30
AR210855A1 (es)	1977-09-30
CS189709B2 (en)	1979-04-30
DD122094A5 (xx)	1976-09-12
IN142267B (xx)	1977-06-18
US4012382A (en)	1977-03-15
ES454964A1 (es)	1978-01-16
CH617202A5 (xx)	1980-05-14
DK559588A (da)	1988-10-06
HU174102B (hu)	1979-11-28
JPS6219160B2 (xx)	1987-04-27
ZA752504B (en)	1976-03-31
FI60867B (fi)	1981-12-31
DD127731A5 (de)	1977-10-12
IE43052L (en)	1975-12-05
FR2296639A1 (fr)	1976-07-30
JPS5111785A (xx)	1976-01-30

Legal Events

Date	Code	Title	Description
1996-09-12	RH	Patent void

Publication	Publication Date	Title
IL53407A0 (en)	1978-01-31	Enzymatic cleavage of alpha-amino-alpha(rho-acetoxyphenylacetamido)desacetoxycephalosporanic acid
JPS5459276A (en)	1979-05-12	Production of diacetonee llketoglonic acid
AU497074B2 (en)	1978-11-23	Production of polyhydric alcohols
AU7912275A (en)	1976-09-16	Enzymatic processes for hydrolyzing proteins
AU8226775A (en)	1976-12-23	Production of acetic acid
AU506969B2 (en)	1980-01-31	Electroregeneration of pickling solutions
AU501389B2 (en)	1979-06-21	Prostaglandin analogues
IL53406A0 (en)	1978-01-31	Enzymatic cleavage of alpha-amino-alpha-(rho-acetoxyphenylacetamido)penicillanic acid
IL47550A (en)	1978-01-31	Production of phosphoric acid
ZA75661B (en)	1976-01-28	Esters of dihydroapovincaminic acid
IL46178A (en)	1978-10-31	Method for the performance of enzymatic reactions
CS183850B2 (en)	1978-07-31	Method of producing 5-fluor-2-methyl-1-/p-methyl-sulphinylbenzyliden/-3-indenylacetic acid
YU40886B (en)	1986-08-31	Process for obtaining new derivativo of 13-thiaprostanoic acid
GB1521763A (en)	1978-08-16	Oxygen analogues of cephalosporins
ZA75194B (en)	1976-01-28	New derivatives of phnylacetic acid
IL46740A0 (en)	1975-05-22	Purification of phosphoric acid
ZA757976B (en)	1976-12-29	Production of chlorocyanuric acid
CA1033768A (en)	1978-06-27	Production of acetone
EG11808A (en)	1978-09-30	Purification of phosphoric acid
ZA751660B (en)	1976-02-25	Purification of hydrochloric acid
IL53406A (en)	1978-07-31	Enzymatic cleavage of -amino- (p-acetoxyphenylacetamido)-penicillanic acid
AU502124B2 (en)	1979-07-12	Analogues of prostanoic acids
JPS57197281A (en)	1982-12-03	Cleavage of cephalosporins
GB1531885A (en)	1978-11-08	Manufacture of sulphamic acid halides
AU498033B2 (en)	1979-02-01	Manufacture of steel