IL157386A0 - A stereoselective process for the preparation of (s)-1-arylethanol derivatives - Google Patents
A stereoselective process for the preparation of (s)-1-arylethanol derivativesInfo
- Publication number
- IL157386A0 IL157386A0 IL15738602A IL15738602A IL157386A0 IL 157386 A0 IL157386 A0 IL 157386A0 IL 15738602 A IL15738602 A IL 15738602A IL 15738602 A IL15738602 A IL 15738602A IL 157386 A0 IL157386 A0 IL 157386A0
- Authority
- IL
- Israel
- Prior art keywords
- arylethanol
- derivatives
- preparation
- stereoselective process
- stereoselective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/938—Pichia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27802501P | 2001-03-22 | 2001-03-22 | |
PCT/US2002/006783 WO2002077258A1 (en) | 2001-03-22 | 2002-03-06 | Stereoselective reduction of substituted acetophenone |
Publications (1)
Publication Number | Publication Date |
---|---|
IL157386A0 true IL157386A0 (en) | 2004-02-19 |
Family
ID=23063377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15738602A IL157386A0 (en) | 2001-03-22 | 2002-03-06 | A stereoselective process for the preparation of (s)-1-arylethanol derivatives |
Country Status (13)
Country | Link |
---|---|
US (1) | US6800477B2 (zh) |
EP (1) | EP1370677A1 (zh) |
JP (1) | JP2004532017A (zh) |
KR (1) | KR20030085012A (zh) |
CN (1) | CN1498273A (zh) |
BR (1) | BR0208265A (zh) |
CA (1) | CA2441267A1 (zh) |
CZ (1) | CZ20032496A3 (zh) |
HU (1) | HUP0400261A3 (zh) |
IL (1) | IL157386A0 (zh) |
MX (1) | MXPA03008437A (zh) |
PL (1) | PL364577A1 (zh) |
WO (1) | WO2002077258A1 (zh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1453516A2 (de) * | 2001-10-17 | 2004-09-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren |
EP1791965A1 (en) * | 2004-08-26 | 2007-06-06 | Pfizer, Inc. | Enantioselective biotransformation for preparation of protein tyrosine kinase inhibitor intermediates |
WO2007084625A2 (en) * | 2006-01-19 | 2007-07-26 | Mount Sinai School Of Medicine | Novel compounds and methods for inhibiting p53 activity |
CN101528917B (zh) * | 2006-10-02 | 2015-07-29 | 科德克希思公司 | 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法 |
JP2010517574A (ja) * | 2007-02-08 | 2010-05-27 | コデクシス, インコーポレイテッド | ケトレダクターゼおよびその使用 |
JP2010536385A (ja) | 2007-08-24 | 2010-12-02 | コデクシス, インコーポレイテッド | (r)−3−ヒドロキシチオランの立体選択的生成のための改善されたケトレダクターゼポリペプチド |
JP5973131B2 (ja) | 2007-09-13 | 2016-08-23 | コデクシス, インコーポレイテッド | アセトフェノンの還元のためのケトレダクターゼポリペプチド |
KR20100061571A (ko) | 2007-09-28 | 2010-06-07 | 코덱시스, 인코포레이티드 | 케토리덕타제 폴리펩티드 및 이의 용도 |
WO2009046153A1 (en) | 2007-10-01 | 2009-04-09 | Codexis, Inc. | Ketoreductase polypeptides for the production of azetidinone |
US8288141B2 (en) | 2008-08-27 | 2012-10-16 | Codexis, Inc. | Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine |
WO2010027710A2 (en) | 2008-08-27 | 2010-03-11 | Codexis, Inc. | Ketoreductase polypeptides and uses thereof |
SI2329013T1 (sl) | 2008-08-27 | 2016-03-31 | Codexis, Inc. | Polipeptidi ketoreduktaze za proizvodnjo 3-aril-3-hidroksipropanamina iz 3-aril-3-ketopropanamina |
US8273554B2 (en) | 2008-08-29 | 2012-09-25 | Codexis, Inc. | Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one |
CN102482648B (zh) | 2009-06-22 | 2014-12-10 | 科德克希思公司 | 酮还原酶介导的产生α氯代醇的立体选择性途径 |
CN102803233B (zh) * | 2009-06-22 | 2017-03-01 | 爱思开生物制药株式会社 | 制备氨基甲酸(r)‑1‑芳基‑2‑四唑基‑乙酯的方法 |
EP2467473B1 (en) | 2009-08-19 | 2016-03-23 | Codexis, Inc. | Ketoreductase polypeptides for the preparation of phenylephrine |
US8404461B2 (en) | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
WO2011100265A2 (en) | 2010-02-10 | 2011-08-18 | Codexis, Inc. | Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system |
EP2566497B1 (en) | 2010-05-04 | 2015-07-29 | Codexis, Inc. | Biocatalysts for ezetimibe synthesis |
WO2012046254A2 (en) * | 2010-10-08 | 2012-04-12 | Cadila Healthcare Limited | Process for preparing an intermediate of sitagliptin via enzymatic conversion |
US9139819B2 (en) | 2011-11-18 | 2015-09-22 | Codexis, Inc. | Biocatalysts for the preparation of hydroxy substituted carbamates |
DE102012017026A1 (de) | 2012-08-28 | 2014-03-06 | Forschungszentrum Jülich GmbH | Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen |
ES2830725T3 (es) | 2015-02-10 | 2021-06-04 | Codexis Inc | Polipéptidos cetoreductasa para la síntesis de compuestos quirales |
CN110831618B (zh) | 2017-04-27 | 2023-08-25 | 科德克希思公司 | 酮还原酶多肽及多核苷酸 |
CN107686447A (zh) * | 2017-08-25 | 2018-02-13 | 许昌恒生制药有限公司 | 一种替格瑞洛中间体的制备方法 |
EP3587393B1 (en) | 2018-06-21 | 2024-01-17 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Enzymatic process for the preparation of droxidopa |
TW202304921A (zh) | 2021-04-02 | 2023-02-01 | 美商建南德克公司 | 製造雙環酮化合物之方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0538693A3 (en) | 1991-10-23 | 1994-08-17 | Squibb & Sons Inc | Stereoselective preparation of halophenyl alcohols |
US5523223A (en) | 1992-03-13 | 1996-06-04 | Forschungszentrum Julich Gmbh | Ketoester reductase for conversion of keto acid esters to optically active hydroxy acid esters |
CA2103932A1 (en) | 1992-11-05 | 1994-05-06 | Ramesh N. Patel | Stereoselective reduction of ketones |
AU1302999A (en) | 1997-11-04 | 1999-05-24 | Eli Lilly And Company | Ketoreductase gene and protein from yeast |
-
2002
- 2002-03-06 BR BR0208265-9A patent/BR0208265A/pt not_active IP Right Cessation
- 2002-03-06 CN CNA028068858A patent/CN1498273A/zh active Pending
- 2002-03-06 CZ CZ20032496A patent/CZ20032496A3/cs unknown
- 2002-03-06 HU HU0400261A patent/HUP0400261A3/hu unknown
- 2002-03-06 EP EP02728418A patent/EP1370677A1/en not_active Withdrawn
- 2002-03-06 IL IL15738602A patent/IL157386A0/xx unknown
- 2002-03-06 MX MXPA03008437A patent/MXPA03008437A/es unknown
- 2002-03-06 PL PL02364577A patent/PL364577A1/xx not_active Application Discontinuation
- 2002-03-06 CA CA002441267A patent/CA2441267A1/en not_active Abandoned
- 2002-03-06 JP JP2002576699A patent/JP2004532017A/ja active Pending
- 2002-03-06 WO PCT/US2002/006783 patent/WO2002077258A1/en not_active Application Discontinuation
- 2002-03-06 US US10/092,263 patent/US6800477B2/en not_active Expired - Lifetime
- 2002-03-06 KR KR10-2003-7012198A patent/KR20030085012A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002077258A1 (en) | 2002-10-03 |
CA2441267A1 (en) | 2002-10-03 |
CN1498273A (zh) | 2004-05-19 |
KR20030085012A (ko) | 2003-11-01 |
HUP0400261A2 (hu) | 2004-09-28 |
HUP0400261A3 (en) | 2005-11-28 |
US20030068811A1 (en) | 2003-04-10 |
PL364577A1 (en) | 2004-12-13 |
US6800477B2 (en) | 2004-10-05 |
CZ20032496A3 (cs) | 2003-12-17 |
EP1370677A1 (en) | 2003-12-17 |
JP2004532017A (ja) | 2004-10-21 |
MXPA03008437A (es) | 2004-01-29 |
BR0208265A (pt) | 2004-03-02 |
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