IL147327A0 - Respiratory syncytial virus replication inhibitors - Google Patents

Respiratory syncytial virus replication inhibitors

Info

Publication number
IL147327A0
IL147327A0 IL14732700A IL14732700A IL147327A0 IL 147327 A0 IL147327 A0 IL 147327A0 IL 14732700 A IL14732700 A IL 14732700A IL 14732700 A IL14732700 A IL 14732700A IL 147327 A0 IL147327 A0 IL 147327A0
Authority
IL
Israel
Prior art keywords
respiratory syncytial
syncytial virus
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
IL14732700A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL147327A0 publication Critical patent/IL147327A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL14732700A 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors IL147327A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202088 1999-06-28
PCT/EP2000/005675 WO2001000612A2 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (1)

Publication Number Publication Date
IL147327A0 true IL147327A0 (en) 2002-08-14

Family

ID=8240373

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14732700A IL147327A0 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors
IL147327A IL147327A (en) 1999-06-28 2001-12-26 Benzoimidiazoles and imidazopyridines, process and intermediates for their preparation, pharmaceutical preparations containing them and their use in the preparation of drugs for the treatment or prevention of sensory viral infection

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL147327A IL147327A (en) 1999-06-28 2001-12-26 Benzoimidiazoles and imidazopyridines, process and intermediates for their preparation, pharmaceutical preparations containing them and their use in the preparation of drugs for the treatment or prevention of sensory viral infection

Country Status (33)

Country Link
US (3) US6747028B1 (es)
EP (1) EP1196409B1 (es)
JP (1) JP2003503402A (es)
KR (1) KR100731271B1 (es)
CN (1) CN1210275C (es)
AR (1) AR035991A1 (es)
AT (1) ATE258928T1 (es)
AU (1) AU778218B2 (es)
BG (1) BG65328B1 (es)
BR (1) BR0012047A (es)
CA (1) CA2376676C (es)
DE (1) DE60008112T2 (es)
DK (1) DK1196409T3 (es)
EA (1) EA005027B1 (es)
EE (1) EE04591B1 (es)
ES (1) ES2215683T3 (es)
HK (1) HK1045997A1 (es)
HR (1) HRP20010935A2 (es)
HU (1) HUP0201869A3 (es)
IL (2) IL147327A0 (es)
MX (1) MXPA02000120A (es)
MY (1) MY127687A (es)
NO (1) NO322458B1 (es)
NZ (1) NZ515664A (es)
PL (1) PL200674B1 (es)
PT (1) PT1196409E (es)
SI (1) SI1196409T1 (es)
SK (1) SK19122001A3 (es)
TR (1) TR200103806T2 (es)
TW (1) TWI278454B (es)
UA (1) UA74787C2 (es)
WO (1) WO2001000612A2 (es)
ZA (1) ZA200110479B (es)

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KR100731271B1 (ko) 1999-06-28 2007-06-21 얀센 파마슈티카 엔.브이. 호흡기 신시티움 바이러스 복제 억제제
SI1196408T1 (en) * 1999-06-28 2005-02-28 Janssen Pharmaceutica N.V. Respiratory syncytial virus replication inhibitors
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
US6774134B2 (en) 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
US7030150B2 (en) 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
US6919331B2 (en) 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
US8202896B2 (en) 2002-08-09 2012-06-19 Microdose Therapeutx, Inc. Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
CA2495245A1 (en) 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
AU2003301436A1 (en) * 2002-10-17 2004-05-04 Amgen Inc. Benzimidazole derivatives and their use as vanilloid receptor ligands
EP1682547B1 (en) 2003-10-30 2012-10-24 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors
CN1894239A (zh) 2003-12-18 2007-01-10 泰博特克药品有限公司 作为呼吸道合胞病毒复制的抑制剂的哌啶－氨基－苯并咪唑类衍生物
AR046971A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Aminobenzoimidazoles y benzoimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
AR046972A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Derivados de los amino-bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
DK1697347T3 (da) * 2003-12-18 2011-06-06 Tibotec Pharm Ltd 5- eller 6-substituerede benzimidazolderivater som inhibitorer af replikation af respiratorisk syncytial-virus
MXPA06007110A (es) * 2003-12-18 2006-08-23 Tibotec Pharm Ltd Derivados de los amino-bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio.
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MX2007011292A (es) 2005-03-17 2007-11-07 Tibotec Pharm Ltd 1,3-dihidro-bencimidazol-2-ilidenaminas como inhibidores de replicacion de virus respiratorios sinciciales.
BRPI0612628B8 (pt) 2005-06-20 2021-05-25 Janssen R & D Ireland 1-(2-amina-3-(alquil substituído)-3h-benzimidazolil)metil]-3-substituído-1,3-diidro-benzoimidazol-2-onas com atividade sobre vírus sincicial respiratório, seu processo de preparação e composição farmacêutica que os compreende
RU2441866C2 (ru) * 2005-06-20 2012-02-10 Тиботек Фармасьютикалз Лтд 2-замещенные бензимидазолы
CA2612264C (en) 2005-06-20 2014-09-23 Tibotec Pharmaceuticals Ltd. Heterocyclylaminoalkyl substituted benzimidazoles
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TWI541241B (zh) * 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
TWI501967B (zh) 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
US9012450B2 (en) 2011-12-28 2015-04-21 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
FI3738434T3 (fi) 2011-12-28 2023-11-20 Global Blood Therapeutics Inc Välituotteita substituoitujen bentsaldehydiyhdisteiden saamiseksi ja menetelmiä niiden käyttöön kudosten hapetuksen lisäämiseksi
TWI643850B (zh) 2012-06-15 2018-12-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒之抗病毒劑的新穎經雜環取代之１，３－二氫－２ｈ－苯并咪唑－２－酮衍生物
SG11201507349TA (en) 2013-03-15 2015-10-29 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MX2015011445A (es) 2013-03-15 2016-04-20 Global Blood Therapeutics Inc Compuestos y usos de estos para la modulacion de la hemoglobina.
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
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US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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EA202092627A1 (ru) 2013-11-18 2021-09-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
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Also Published As

Publication number Publication date
CN1210275C (zh) 2005-07-13
ES2215683T3 (es) 2004-10-16
CN1358181A (zh) 2002-07-10
US7528149B2 (en) 2009-05-05
ZA200110479B (en) 2003-03-20
SK19122001A3 (sk) 2003-01-09
WO2001000612A2 (en) 2001-01-04
DE60008112D1 (en) 2004-03-11
ATE258928T1 (de) 2004-02-15
BR0012047A (pt) 2002-03-12
US6747028B1 (en) 2004-06-08
BG65328B1 (bg) 2008-02-29
IL147327A (en) 2007-06-03
PL200674B1 (pl) 2009-01-30
WO2001000612A3 (en) 2001-03-29
US20070015747A1 (en) 2007-01-18
PL352378A1 (en) 2003-08-25
EP1196409B1 (en) 2004-02-04
EA005027B1 (ru) 2004-10-28
KR100731271B1 (ko) 2007-06-21
AU5816600A (en) 2001-01-31
HK1045997A1 (zh) 2002-12-20
EA200200088A1 (ru) 2002-06-27
BG106286A (en) 2002-10-31
NO322458B1 (no) 2006-10-09
AU778218B2 (en) 2004-11-25
HUP0201869A3 (en) 2003-12-29
US20070135404A1 (en) 2007-06-14
US7179811B2 (en) 2007-02-20
EE04591B1 (et) 2006-02-15
DK1196409T3 (da) 2004-06-07
KR20020003884A (ko) 2002-01-15
NO20016369D0 (no) 2001-12-27
SI1196409T1 (en) 2004-06-30
HUP0201869A2 (hu) 2002-11-28
AR035991A1 (es) 2004-08-04
UA74787C2 (en) 2006-02-15
JP2003503402A (ja) 2003-01-28
MXPA02000120A (es) 2002-07-02
TWI278454B (en) 2007-04-11
HRP20010935A2 (en) 2003-06-30
MY127687A (en) 2006-12-29
CA2376676C (en) 2009-01-20
EE200100688A (et) 2003-04-15
EP1196409A2 (en) 2002-04-17
PT1196409E (pt) 2004-06-30
TR200103806T2 (tr) 2002-06-21
DE60008112T2 (de) 2004-09-16
CA2376676A1 (en) 2001-01-04
NZ515664A (en) 2004-01-30
NO20016369L (no) 2002-02-20

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