IL144156A0 - Use of imidazo [1,5-a]-pyrido [3,2-e] -pyrazinones as medicaments - Google Patents

Use of imidazo [1,5-a]-pyrido [3,2-e] -pyrazinones as medicaments

Info

Publication number
IL144156A0
IL144156A0 IL14415600A IL14415600A IL144156A0 IL 144156 A0 IL144156 A0 IL 144156A0 IL 14415600 A IL14415600 A IL 14415600A IL 14415600 A IL14415600 A IL 14415600A IL 144156 A0 IL144156 A0 IL 144156A0
Authority
IL
Israel
Prior art keywords
pyrazinones
pyrido
imidazo
medicaments
Prior art date
Application number
IL14415600A
Other languages
English (en)
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1999102082 external-priority patent/DE19902082A1/de
Priority claimed from DE1999161302 external-priority patent/DE19961302A1/de
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of IL144156A0 publication Critical patent/IL144156A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
IL14415600A 1999-01-20 2000-01-14 Use of imidazo [1,5-a]-pyrido [3,2-e] -pyrazinones as medicaments IL144156A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1999102082 DE19902082A1 (de) 1999-01-20 1999-01-20 Verwendung von Imidazo[1,5-a]-pyrido[3,2-e]-pyrazinonen als Inhibitoren der Phosphodiesterase 5 zur Therapie von erectiler Dysfunktion und Verfahren zu deren Herstellung
DE1999161302 DE19961302A1 (de) 1999-12-18 1999-12-18 Verwendung von Imidazo(1,5-a)-pyrido(3,2-e)-pyrazinonen als duale Inhibitoren der Phosphodiesterase 5 und der Phosphodiesterase 3 zur Therapie der Herzinsuffizienz, von pulmonaler Hypertonie und Gefäßerkrankungen, die mit einer Minderdurchblutung einhergehen
PCT/EP2000/000260 WO2000043392A2 (de) 1999-01-20 2000-01-14 Verwendung von imidazo[1,5-a]-pyrido[3,2-e]-pyrazinonen als arzneimittel

Publications (1)

Publication Number Publication Date
IL144156A0 true IL144156A0 (en) 2002-05-23

Family

ID=26051406

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14415600A IL144156A0 (en) 1999-01-20 2000-01-14 Use of imidazo [1,5-a]-pyrido [3,2-e] -pyrazinones as medicaments

Country Status (23)

Country Link
EP (1) EP1144410A2 (id)
JP (1) JP2002535330A (id)
KR (1) KR20010101603A (id)
CN (1) CN1344268A (id)
AR (1) AR022318A1 (id)
AU (1) AU2291200A (id)
BG (1) BG105714A (id)
BR (1) BR0007613A (id)
CA (1) CA2296224A1 (id)
CO (1) CO5190700A1 (id)
CZ (1) CZ20012627A3 (id)
EA (1) EA200100792A1 (id)
EE (1) EE200100377A (id)
HU (1) HUP0105132A3 (id)
ID (1) ID29790A (id)
IL (1) IL144156A0 (id)
IS (1) IS5987A (id)
LT (1) LT2001078A (id)
LV (1) LV12793B (id)
NO (1) NO20013334L (id)
SK (1) SK10322001A3 (id)
TR (1) TR200102121T2 (id)
WO (1) WO2000043392A2 (id)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548490B1 (en) * 1997-10-28 2003-04-15 Vivus, Inc. Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
US6403597B1 (en) 1997-10-28 2002-06-11 Vivus, Inc. Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
EP1461022A2 (en) * 2001-12-17 2004-09-29 ALTANA Pharma AG Use of selective pde5 inhibitors for treating partial and global respiratory failure
US6916345B2 (en) 2002-02-12 2005-07-12 L'oreal S.A. 6-alkoxy-2,3-diaminopyridine couplers for dyeing keratin fibres
FR2835741B1 (fr) * 2002-02-12 2006-05-05 Oreal Nouveaux coupleurs 6-alcoxy-2,3-diaminopyridine utiles pour la teinture des fibres keratiniques
DE10325813B4 (de) 2003-06-06 2007-12-20 Universitätsklinikum Freiburg Prophylaxe und/oder Therapie bei der portalen Hypertonie
CA2577442A1 (en) * 2004-08-17 2006-03-02 The Johns Hopkins University Pde5 inhibitor compositions and methods for treating cardiac indications
ES2536906T3 (es) * 2006-12-13 2015-05-29 Aska Pharmaceutical Co., Ltd. Derivado de quinoxalina
WO2009070583A1 (en) * 2007-11-30 2009-06-04 Wyeth Pyrido[3,2-e]pyrazines, process for preparing the same, and their use as inhibitors of phosphodiesterase 10
CA2706866A1 (en) 2007-11-30 2009-06-04 Biotie Therapies Gmbh Aryl and heteroaryl fused imidazo[1,5-a]pyrazines as inhibitors of phosphodiesterase 10
JP2015531401A (ja) 2011-10-10 2015-11-02 ハー・ルンドベック・アクチエゼルスカベット イミダゾピラジノン骨格を有するｐｄｅ９ｉ
US9434733B2 (en) 2012-01-26 2016-09-06 H. Lundbeck A/S PDE9 inhibitors with imidazo triazinone backbone
JP5842640B2 (ja) * 2012-01-31 2016-01-13 株式会社東洋新薬 ホスホジエステラーゼ３阻害剤
WO2016022825A1 (en) * 2014-08-07 2016-02-11 Intra-Cellular Therapies, Inc. Organic compounds
US10005789B2 (en) 2014-08-07 2018-06-26 Intra-Cellular Therapies, Inc. Organic compounds
TN2017000507A1 (en) 2015-07-07 2019-04-12 H Lundbeck As Pde9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055465A (en) * 1989-05-31 1991-10-08 Berlex Laboratories, Inc. Imidazoquinoxalinones, their aza analogs and process for their preparation
DE19510965A1 (de) * 1995-03-24 1996-09-26 Asta Medica Ag Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
AR022318A1 (es) 2002-09-04
IS5987A (is) 2001-06-29
WO2000043392A2 (de) 2000-07-27
LT2001078A (en) 2002-08-26
EA200100792A1 (ru) 2002-10-31
AU2291200A (en) 2000-08-07
JP2002535330A (ja) 2002-10-22
CZ20012627A3 (cs) 2002-01-16
CA2296224A1 (en) 2000-07-20
BG105714A (en) 2002-02-28
NO20013334D0 (no) 2001-07-05
ID29790A (id) 2001-10-11
HUP0105132A3 (en) 2002-12-28
NO20013334L (no) 2001-07-05
EP1144410A2 (de) 2001-10-17
WO2000043392A3 (de) 2000-09-28
KR20010101603A (ko) 2001-11-14
LV12793B (lv) 2002-05-20
CN1344268A (zh) 2002-04-10
LV12793A (lv) 2002-02-20
HUP0105132A2 (hu) 2002-05-29
TR200102121T2 (tr) 2002-01-21
EE200100377A (et) 2002-10-15
CO5190700A1 (es) 2002-08-29
BR0007613A (pt) 2001-10-30
SK10322001A3 (sk) 2002-07-02

Similar Documents

Publication Publication Date Title
HUP0202494A2 (en) Imidazo[1,2-a]pyridine and pyrazolo[2,3-a]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0203503A3 (en) Pyrrolo[2,3-d]pirimidine compounds, pharmaceutical compositions containing them and their use
HUP0500332A3 (en) Substituted 2-pyrimidinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyrimidinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)-one derivatives, their use and pharmaceutical compositions containing them
IL133959A0 (en) Triazolo [4,5-d] pyrimidine compounds, their use anovel compounds s medicaments, compositions containing them and processes for their preparation
HUP0105081A3 (en) Triazolo[4,5-d]pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HK1024914A1 (en) 1,2,4-triazolo 4,3-b]pyrido 3,2-d]pyridazine derivatives and pharmaceutical compositions containing them
IL191960A (en) History of imidazo [5,1– a] pyridine and pharmaceutical preparations containing them
HUP0303350A3 (en) Use of substituted imidazo[1,2-a]pyridine-, imidazo[1,2-a]pyrimidine and imidazo[1,2-a]pyrazine-3-yl-amine derivatives for producing nos-inhibiting pharmaceutical compositions
HUP0204246A3 (en) Novel thiazolo[4,5-d]pyrimidine compounds, process for their preparation, pharmaceutical compositions containing them and their use
IL144156A0 (en) Use of imidazo [1,5-a]-pyrido [3,2-e] -pyrazinones as medicaments
NZ330988A (en) 5h-thiazolo[3,2-a]pyrimidine derivatives used as neurological medicaments
HUP0402018A3 (en) 5-amino-7h-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives, their use and pharmaceutical compositions containing them
HUP0500328A3 (en) Substituted 2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a]pyrimidin-5(1h)-one derivatives, their use and pharmaceutical compositions containing them
AU2002361407A1 (en) Triazolo(4,3-a)pyrido(2,3-d)pyrimidin-5-one derivatives, compositions containing same, preparation method and use thereof
PL349364A1 (en) Use of pyridazino[4,5-b
IL156536A0 (en) Pyrazolo [3,4-d] pyrimidin-4-one derivatives and pharmaceutical compositions containing the same
PL366858A1 (en) Use of substituted imidazo[1,2-a]-pyridine compounds as medicaments
HUP0202624A3 (en) Pyrazolo[4,3-d]pyrimidine-derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0102981A3 (en) Pyrrolo[1,2-a]pyrazine derivatives and pharmaceutical compositions thereof
HUP0105054A3 (en) Imidazo[4,5-c]-pyridine-4-on-derivatives, pharmaceutical compositions containing them and process for their preparation
HUP0003118A3 (en) Use of 2,7-substituted octahydro-1h-pyrido [1,2-a]pyrazine derivatives for production of pharmaceutical compositions
HUP0103075A3 (en) Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one derivatives and intermediates thereof
MXPA03008894A (es) Uso de compuestos de imidazo[1,2-a]-piridin-3-il-amidas e imidazo [1,2-a]-piridin-3-il-aminas sustituidas como medicamentos.
HU0003979D0 (en) Process for the preparation of 3-pyridylsulphonil-pyrazolo[4,3-d] pyrimidin-7-one derivatives and intermediates thereof
HUP0203579A3 (en) Pyrazolo[1,5-d][1,2,4]triazines for enhancing cognition and pharmaceutical compositions containing them and their use