IL137388A - Absorbable microparticles - Google Patents

Absorbable microparticles

Info

Publication number
IL137388A
IL137388A IL13738899A IL13738899A IL137388A IL 137388 A IL137388 A IL 137388A IL 13738899 A IL13738899 A IL 13738899A IL 13738899 A IL13738899 A IL 13738899A IL 137388 A IL137388 A IL 137388A
Authority
IL
Israel
Prior art keywords
absorbable
microparticles
absorbable microparticles
Prior art date
Application number
IL13738899A
Other languages
English (en)
Inventor
Shalaby Wahba Shalaby
Original Assignee
Poly Med Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poly Med Inc filed Critical Poly Med Inc
Publication of IL137388A publication Critical patent/IL137388A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6927Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL13738899A 1998-01-29 1999-01-20 Absorbable microparticles IL137388A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1539498A 1998-01-29 1998-01-29

Publications (1)

Publication Number Publication Date
IL137388A true IL137388A (en) 2005-05-17

Family

ID=21771154

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13738899A IL137388A (en) 1998-01-29 1999-01-20 Absorbable microparticles
IL13738800A IL137388A0 (en) 1998-01-29 2000-01-20 Absorbable microparticles

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13738800A IL137388A0 (en) 1998-01-29 2000-01-20 Absorbable microparticles

Country Status (19)

Country Link
US (1) US20060210641A1 (xx)
EP (1) EP1053020B1 (xx)
JP (2) JP3842042B2 (xx)
CN (1) CN1289256A (xx)
AR (1) AR014510A1 (xx)
AT (1) ATE262926T1 (xx)
AU (1) AU2329199A (xx)
CA (1) CA2318152A1 (xx)
DE (1) DE69916031T2 (xx)
DK (1) DK1053020T3 (xx)
ES (1) ES2217738T3 (xx)
HU (1) HUP0101250A3 (xx)
IL (2) IL137388A (xx)
NO (1) NO20003810L (xx)
PL (1) PL193111B1 (xx)
PT (1) PT1053020E (xx)
RU (1) RU2237471C2 (xx)
TW (1) TWI255721B (xx)
WO (1) WO1999038536A1 (xx)

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US6413539B1 (en) * 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
AU2002214942A1 (en) * 2000-11-16 2002-05-27 Novo-Nordisk A/S Analogues and derivatives of gastrin releasing peptide (grp)
FR2825273B1 (fr) * 2001-05-29 2006-11-24 Oreal Composition pour le traitement des signes cutanes du vieillissement
CA2551039C (en) 2003-12-16 2013-01-29 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Analogues of glp-1
JP2007517913A (ja) * 2004-01-13 2007-07-05 バソジェニックス ファーマシューティカルズ, インコーポレイテッド カルシトニン遺伝子関連ペプチドを投与することによって急性心筋梗塞を処置するための方法およびカルシトニン遺伝子関連ペプチドを含有する組成物
JP2007517912A (ja) * 2004-01-13 2007-07-05 バソジェニックス ファーマシューティカルズ, インコーポレイテッド 心脈管および腎臓の適応症のための制御放出cgrp送達組成物
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
ES2430067T3 (es) 2007-03-28 2013-11-18 President And Fellows Of Harvard College Polipéptidos cosidos
WO2009035540A2 (en) 2007-09-07 2009-03-19 Ipsen Pharma S.A.S. Analogues of exendin-4 and exendin-3
MX2011000147A (es) 2008-07-04 2011-05-24 Traslational Cancer Drugs Pharma S L Metodos para el tratamiento y diagnostico del cancer.
CN102170896A (zh) 2008-08-07 2011-08-31 益普生制药股份有限公司 糖依赖性胰岛素释放肽的截短类似物
AU2009280017B2 (en) 2008-08-07 2013-01-10 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide
AU2009280021B2 (en) 2008-08-07 2012-10-04 Ipsen Pharma S.A.S. Analogues of glucose-dependent insulinotropic polypeptide (GIP) modified at N-terminal
WO2010092218A2 (es) 2009-02-12 2010-08-19 Proyecto De Biomedicina Cima, S.L. Uso de la cardiotrofina-1 para el tratamiento de enfermedades metabólicas
MX2012000757A (es) 2009-07-22 2012-08-03 Ipsen Pharma Sas Analogos de factor de crecimiento insulinoide tipo 1 (igf-1) que tienen sustitucion de aminoacidos en la posicion 59.
US9517257B2 (en) 2010-08-10 2016-12-13 Ecole Polytechnique Federale De Lausanne (Epfl) Erythrocyte-binding therapeutics
CA2807942C (en) * 2010-08-10 2021-07-27 Ecole Polytechnique Federale De Lausanne Erythrocyte-binding therapeutics
WO2012021874A1 (en) 2010-08-13 2012-02-16 Aileron Therapeutics, Inc. Peptidomimetic macrocycles with thioether linkers
EA018472B1 (ru) * 2010-09-15 2013-08-30 Открытое Акционерное Общество "Протек" Частицы, содержащие эритропоэтин, для лечения и профилактики неврологических и гематологических заболеваний и нарушений
WO2012172433A2 (en) * 2011-06-14 2012-12-20 Ipsen Pharma S.A.S. A sustained-release composition containing peptides as active ingredient
BR112014009418A2 (pt) 2011-10-18 2017-04-18 Aileron Therapeutics Inc macrociclos peptidomiméticos
CN103957898B (zh) 2011-11-18 2016-02-24 瑞泽恩制药公司 聚合物蛋白微粒
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
AU2013221432B2 (en) 2012-02-15 2018-01-18 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
JP6526563B2 (ja) 2012-11-01 2019-06-05 エイルロン セラピューティクス,インコーポレイテッド 二置換アミノ酸ならびにその調製および使用の方法
EP3107563B1 (en) 2014-02-21 2021-04-07 Ecole Polytechnique Fédérale de Lausanne (EPFL) EPFL-TTO Glycotargeting therapeutics
US10953101B2 (en) 2014-02-21 2021-03-23 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
US10946079B2 (en) 2014-02-21 2021-03-16 Ecole Polytechnique Federale De Lausanne Glycotargeting therapeutics
US10046056B2 (en) 2014-02-21 2018-08-14 École Polytechnique Fédérale De Lausanne (Epfl) Glycotargeting therapeutics
CA2961258A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN107614003A (zh) 2015-03-20 2018-01-19 艾瑞朗医疗公司 拟肽大环化合物及其用途
WO2017077066A1 (en) 2015-11-06 2017-05-11 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Composition comprising a biocompatible and biodegradable polymer, nanocarries and a drug and methods of making and using the same
US11253579B2 (en) 2017-06-16 2022-02-22 The University Of Chicago Compositions and methods for inducing immune tolerance
CN113281317B (zh) * 2021-05-14 2022-04-29 北京指真生物科技有限公司 一种含有花菁类化合物的编码微球及其制备方法和应用

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* Cited by examiner, † Cited by third party
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IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US5385738A (en) * 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
JPH0778017B2 (ja) * 1985-12-28 1995-08-23 住友製薬株式会社 パルス的かつ持続放出性製剤
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5077049A (en) * 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
CA2099376A1 (en) * 1991-01-03 1992-07-04 Henry E. Auer Stabilization of proteins by cationic biopolymers
CA2114122A1 (en) * 1991-07-24 1993-02-04 Thomas Sai Ying Ko Therapeutic compositions and methods
US5366756A (en) * 1992-06-15 1994-11-22 United States Surgical Corporation Method for treating bioabsorbable implant material
US5672659A (en) * 1993-01-06 1997-09-30 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
EP0626170A3 (en) * 1993-05-10 1996-03-27 Sandoz Ltd Stabilization of pharmacoligically active compounds in controlled release compositions.
EP0712421A1 (en) * 1993-07-23 1996-05-22 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
US5612052A (en) * 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US5665702A (en) * 1995-06-06 1997-09-09 Biomeasure Incorporated Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
KR100210509B1 (ko) * 1996-01-10 1999-07-15 성재갑 지속성 동물 성장 호르몬 제형 및 이의 제조 방법

Also Published As

Publication number Publication date
ES2217738T3 (es) 2004-11-01
JP2005047928A (ja) 2005-02-24
TWI255721B (en) 2006-06-01
JP3842042B2 (ja) 2006-11-08
US20060210641A1 (en) 2006-09-21
HUP0101250A3 (en) 2006-06-28
IL137388A0 (en) 2001-07-24
AR014510A1 (es) 2001-02-28
CN1289256A (zh) 2001-03-28
HUP0101250A2 (hu) 2001-08-28
DE69916031T2 (de) 2005-02-17
RU2237471C2 (ru) 2004-10-10
ATE262926T1 (de) 2004-04-15
DK1053020T3 (da) 2004-07-26
PL193111B1 (pl) 2007-01-31
AU2329199A (en) 1999-08-16
PT1053020E (pt) 2004-06-30
NO20003810L (no) 2000-09-13
JP2002501908A (ja) 2002-01-22
EP1053020B1 (en) 2004-03-31
DE69916031D1 (de) 2004-05-06
PL342662A1 (en) 2001-07-02
NO20003810D0 (no) 2000-07-25
EP1053020A1 (en) 2000-11-22
CA2318152A1 (en) 1999-08-05
WO1999038536A1 (en) 1999-08-05

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