IL134079A - Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient - Google Patents

Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient

Info

Publication number
IL134079A
IL134079A IL13407900A IL13407900A IL134079A IL 134079 A IL134079 A IL 134079A IL 13407900 A IL13407900 A IL 13407900A IL 13407900 A IL13407900 A IL 13407900A IL 134079 A IL134079 A IL 134079A
Authority
IL
Israel
Prior art keywords
pellets
water
process according
coating
active ingredient
Prior art date
Application number
IL13407900A
Other languages
English (en)
Other versions
IL134079A0 (en
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of IL134079A0 publication Critical patent/IL134079A0/xx
Publication of IL134079A publication Critical patent/IL134079A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13407900A 1999-01-18 2000-01-17 Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient IL134079A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19901692A DE19901692C2 (de) 1999-01-18 1999-01-18 Verfahren zur Herstellung von Pellets mit einem Gehalt von bis zu 90 Gew.% eines pharmazeutischen Wirkstoffes

Publications (2)

Publication Number Publication Date
IL134079A0 IL134079A0 (en) 2001-04-30
IL134079A true IL134079A (en) 2004-12-15

Family

ID=7894569

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13407900A IL134079A (en) 1999-01-18 2000-01-17 Process for the preparation of pellets with a content of up to 90 wt.% of a pharmaceutical active ingredient

Country Status (18)

Country Link
US (1) US6558704B1 (ja)
EP (1) EP1020181A1 (ja)
JP (1) JP2000212068A (ja)
KR (1) KR20000076475A (ja)
CN (1) CN1161108C (ja)
AU (1) AU764280C (ja)
CA (1) CA2295470A1 (ja)
CO (1) CO4910118A1 (ja)
CZ (1) CZ291936B6 (ja)
DE (1) DE19901692C2 (ja)
HU (1) HUP0000141A3 (ja)
IL (1) IL134079A (ja)
NZ (1) NZ502264A (ja)
PE (1) PE20001414A1 (ja)
PL (1) PL337864A1 (ja)
RU (1) RU2221553C2 (ja)
SK (1) SK285423B6 (ja)
ZA (1) ZA200000169B (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203623A2 (hu) * 1999-08-31 2003-02-28 Grünenthal GmbH Tramadol-szacharinátot tartalmazó, késleltetett hatású adagolási forma és alkalmazása
FR2827771B1 (fr) * 2001-07-25 2003-10-24 Apis Spheromont Formulation et procede de preparation de spheroides pouvant etre fortement titres et a dispersion rapide
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
EP1519704A2 (en) * 2002-06-27 2005-04-06 Cilag AG Spherical pellet containing a water-soluble active ingredient
TW200404004A (en) * 2002-09-09 2004-03-16 Ss Pharmaceutical Co Molded medicament for promotion of sleeping
KR100510270B1 (ko) * 2002-11-29 2005-08-26 센츄론(주) 펠렛타이저를 이용한 서방성 제제의 제조방법
US9107804B2 (en) 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
CA2529984C (en) 2003-06-26 2012-09-25 Isa Odidi Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
EP1629834A1 (en) † 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
WO2007008752A2 (en) * 2005-07-07 2007-01-18 Farnam Companies, Inc. Sustained release pharmaceutical compositions for highly water soluble drugs
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
CA2648278C (en) * 2006-04-03 2019-05-28 Isa Odidi Drug delivery composition
JP5457830B2 (ja) 2006-04-03 2014-04-02 オディディ，イサ オルガノゾル被膜を含む制御放出送達デバイス
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US7979151B2 (en) * 2007-12-06 2011-07-12 International Business Machines Corporation Run-time dispatch system for enhanced product characterization capability
TWI400089B (zh) * 2009-11-24 2013-07-01 Nippon Soda Co 羥烷基纖維素微粒子
DE102012007671A1 (de) 2012-04-16 2013-10-17 Acino Pharma Ag Pellets mit hohem Wirkstoffgehalt
US10966928B2 (en) 2016-03-25 2021-04-06 Universiteit Gent Oral dosage form
WO2017162852A1 (en) 2016-03-25 2017-09-28 Universiteit Gent Oral dosage form
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2018087109A1 (de) 2016-11-08 2018-05-17 Grünenthal GmbH Multipartikuläre arzneiform mit kontrollierter freisetzung von metamizol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234697A (en) * 1992-06-22 1993-08-10 Digestive Care Inc. Compositions of gastric acid-resistant microspheres containing salts of bile acids
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
DE19710008A1 (de) * 1997-03-12 1998-09-17 Basf Ag Feste, mindestens zweiphasige Zubereitungsformen eines Opioid-Analgeticums mit verzögerter Freisetzung

Also Published As

Publication number Publication date
SK682000A3 (en) 2000-08-14
AU1244200A (en) 2000-07-20
ZA200000169B (en) 2000-08-07
CZ2000167A3 (cs) 2000-09-13
HUP0000141A2 (hu) 2000-12-28
IL134079A0 (en) 2001-04-30
CA2295470A1 (en) 2000-07-18
KR20000076475A (ko) 2000-12-26
SK285423B6 (sk) 2007-01-04
HU0000141D0 (en) 2000-03-28
CN1270025A (zh) 2000-10-18
US6558704B1 (en) 2003-05-06
PL337864A1 (en) 2000-07-31
EP1020181A1 (de) 2000-07-19
RU2221553C2 (ru) 2004-01-20
AU764280B2 (en) 2003-08-14
DE19901692C2 (de) 2002-06-20
DE19901692A1 (de) 2000-07-20
AU764280C (en) 2004-06-24
CN1161108C (zh) 2004-08-11
PE20001414A1 (es) 2000-12-23
NZ502264A (en) 2001-11-30
CZ291936B6 (cs) 2003-06-18
JP2000212068A (ja) 2000-08-02
CO4910118A1 (es) 2000-04-24
HUP0000141A3 (en) 2001-01-29

Similar Documents

Publication Publication Date Title
AU764280B2 (en) Process for the preparation of pellets with a content of up to 90 wt. per cent of a pharmaceutical active ingredient
AU2002314968B2 (en) Controlled release dosage forms using acrylic polymer, and process for making the same
EP1976489B1 (en) Multiple unit type sustained release oral formulation comprising zaltoprofen and process for the preparation thereof
KR100563342B1 (ko) 맛이 차단된 약학 조성물
NO853249L (no) Pellet-preparat.
AU2002314968A1 (en) Controlled release dosage forms using acrylic polymer, and process for making the same
JPH0122245B2 (ja)
EP1293208A1 (en) Pharmaceutical formulation
CZ155094A3 (en) Preparation with maintained release and process for preparing pharmaceutical preparations
JP2003514019A (ja) カルベジロールメタンスルホン酸塩
EP2153834A2 (en) Extended release pharmaceutical compositions comprising quetiapine salts
CN101601663A (zh) 左乙拉西坦的多单元缓释制剂及其制备方法
HU204694B (en) Process for producing granulated pharmacetuical compositions comprising captopril
KR100214792B1 (ko) 저작 가능한 약제학적 정제를 제조하기위한 회전제립물 및 맛 차단 제피
CN104997748A (zh) 一种治疗高血压急症的硝苯地平缓释片剂及其制备工艺
JPH03500288A (ja) 徐放性ニフェジピン製剤
SK50442006A3 (sk) Pelety obsahujúce hydrochlorid venlafaxínu
MXPA00000602A (en) Process for producing pellets with a pharmaceutical agent content of up to 90
WO2008062426A2 (en) Formulation of benzazepine derivatives
WO2013124832A2 (en) Stabilized controlled-release pharmaceutical composition comprising gliclazide
CA3111908A1 (en) Methods and compositions for delivering mycophenolic acid active agents to non-human mammals
SK50282011A3 (sk) Controlled acetylsalicylic acid release combined peroral preparation and method for the production thereof
SK6002Y1 (sk) Combined peroral controlled-release formulation of acetylsalicylic acid
MXPA06009167A (en) Particulates
MXPA00004573A (en) Novel oral dosage form for carvedilol

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees