IL122242A - Combination of an angiotensin II receptor antigen and an epoxy-steroidal aldosterone receptor antigen - Google Patents

Combination of an angiotensin II receptor antigen and an epoxy-steroidal aldosterone receptor antigen

Info

Publication number
IL122242A
IL122242A IL12224296A IL12224296A IL122242A IL 122242 A IL122242 A IL 122242A IL 12224296 A IL12224296 A IL 12224296A IL 12224296 A IL12224296 A IL 12224296A IL 122242 A IL122242 A IL 122242A
Authority
IL
Israel
Prior art keywords
angiotensin
epoxy
receptor antagonist
compound
oxo
Prior art date
Application number
IL12224296A
Other languages
English (en)
Hebrew (he)
Other versions
IL122242A0 (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL122242A0 publication Critical patent/IL122242A0/xx
Publication of IL122242A publication Critical patent/IL122242A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
IL12224296A 1995-06-07 1996-06-05 Combination of an angiotensin II receptor antigen and an epoxy-steroidal aldosterone receptor antigen IL122242A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48645695A 1995-06-07 1995-06-07
PCT/US1996/009335 WO1996040257A1 (en) 1995-06-07 1996-06-05 Epoxy-steroidal aldosterone antagonist and angiotensin ii antagonist combination therapy for treatment of congestive heart failure

Publications (2)

Publication Number Publication Date
IL122242A0 IL122242A0 (en) 1998-04-05
IL122242A true IL122242A (en) 2001-07-24

Family

ID=23931955

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12224296A IL122242A (en) 1995-06-07 1996-06-05 Combination of an angiotensin II receptor antigen and an epoxy-steroidal aldosterone receptor antigen

Country Status (21)

Country Link
US (1) US6653306B1 (da)
EP (1) EP0831910B1 (da)
JP (1) JPH11507627A (da)
KR (1) KR100618466B1 (da)
CN (2) CN1522701A (da)
AT (1) ATE209047T1 (da)
AU (1) AU725689B2 (da)
BR (1) BR9609066A (da)
CA (1) CA2224079A1 (da)
CZ (1) CZ297975B6 (da)
DE (1) DE69617235T2 (da)
DK (1) DK0831910T3 (da)
ES (1) ES2167571T3 (da)
IL (1) IL122242A (da)
NO (1) NO318184B1 (da)
NZ (1) NZ310730A (da)
PL (1) PL185150B1 (da)
PT (1) PT831910E (da)
RO (1) RO118046B1 (da)
RU (1) RU2166330C2 (da)
WO (1) WO1996040257A1 (da)

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US6201002B1 (en) 1997-01-10 2001-03-13 Merck & Co., Inc. Method for reducing mortality with an angiotensin II antagonist
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US6306826B1 (en) 1997-06-04 2001-10-23 The Regents Of The University Of California Treatment of heart failure with growth hormone
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US6211217B1 (en) 1999-03-16 2001-04-03 Novartis Ag Method for reducing pericardial fibrosis and adhesion formation
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WO2002009761A2 (en) * 2000-07-27 2002-02-07 Pharmacia Corporation Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of congestive heart failure
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JP5547099B2 (ja) 2008-03-14 2014-07-09 インテリカイン， エルエルシー キナーゼ阻害剤および使用方法
US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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US8476431B2 (en) 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
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Also Published As

Publication number Publication date
KR100618466B1 (ko) 2006-12-13
CN1522701A (zh) 2004-08-25
BR9609066A (pt) 1999-01-26
NO975741D0 (no) 1997-12-05
CZ297975B6 (cs) 2007-05-09
JPH11507627A (ja) 1999-07-06
NO318184B1 (no) 2005-02-14
US6653306B1 (en) 2003-11-25
IL122242A0 (en) 1998-04-05
CN1142793C (zh) 2004-03-24
PT831910E (pt) 2002-05-31
DK0831910T3 (da) 2002-05-21
KR19990022548A (ko) 1999-03-25
ATE209047T1 (de) 2001-12-15
EP0831910B1 (en) 2001-11-21
AU6157796A (en) 1996-12-30
CZ385097A3 (cs) 1998-06-17
CA2224079A1 (en) 1996-12-19
ES2167571T3 (es) 2002-05-16
PL324001A1 (en) 1998-04-27
NZ310730A (en) 2001-01-26
EP0831910A1 (en) 1998-04-01
CN1192697A (zh) 1998-09-09
WO1996040257A1 (en) 1996-12-19
NO975741L (no) 1998-01-29
PL185150B1 (pl) 2003-03-31
RU2166330C2 (ru) 2001-05-10
AU725689B2 (en) 2000-10-19
DE69617235T2 (de) 2002-07-25
DE69617235D1 (de) 2002-01-03
RO118046B1 (ro) 2003-01-30

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