IE57182B1 - 1,4-dihydropyridine derivatives - Google Patents

1,4-dihydropyridine derivatives

Info

Publication number
IE57182B1
IE57182B1 IE831/84A IE83184A IE57182B1 IE 57182 B1 IE57182 B1 IE 57182B1 IE 831/84 A IE831/84 A IE 831/84A IE 83184 A IE83184 A IE 83184A IE 57182 B1 IE57182 B1 IE 57182B1
Authority
IE
Ireland
Prior art keywords
compound
furoyl
dimethyl
general formula
compounds
Prior art date
Application number
IE831/84A
Other languages
English (en)
Other versions
IE840831L (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IE840831L publication Critical patent/IE840831L/xx
Publication of IE57182B1 publication Critical patent/IE57182B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
IE831/84A 1983-04-06 1984-04-04 1,4-dihydropyridine derivatives IE57182B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8309284 1983-04-06

Publications (2)

Publication Number Publication Date
IE840831L IE840831L (en) 1984-10-06
IE57182B1 true IE57182B1 (en) 1992-05-20

Family

ID=10540692

Family Applications (1)

Application Number Title Priority Date Filing Date
IE831/84A IE57182B1 (en) 1983-04-06 1984-04-04 1,4-dihydropyridine derivatives

Country Status (19)

Country Link
US (1) US4529733A (el)
EP (1) EP0124777B1 (el)
JP (1) JPS59193884A (el)
KR (1) KR880002510B1 (el)
AR (1) AR245941A1 (el)
AT (1) ATE23151T1 (el)
AU (1) AU557521B2 (el)
CA (1) CA1262906A (el)
DE (2) DE3461086D1 (el)
DK (1) DK162442C (el)
ES (1) ES531254A0 (el)
GR (1) GR81903B (el)
IE (1) IE57182B1 (el)
IL (1) IL71432A (el)
NO (1) NO157575C (el)
NZ (1) NZ207716A (el)
PH (1) PH19451A (el)
PT (1) PT78370B (el)
ZA (1) ZA842456B (el)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO883326L (no) * 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.
US7150616B2 (en) * 2003-12-22 2006-12-19 Kimberly-Clark Worldwide, Inc Die for producing meltblown multicomponent fibers and meltblown nonwoven fabrics
CN114149360B (zh) * 2021-11-25 2024-03-01 天津太平洋化学制药有限公司 一种高纯度尼群地平原料药的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
ZA7152B (en) * 1970-01-24 1971-10-27 Bayer Ag New pharmaceutically active 1,4-dihydropyridines
DE2117573C3 (de) * 1971-04-10 1978-07-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AU557521B2 (en) 1986-12-24
JPS59193884A (ja) 1984-11-02
DK162442C (da) 1992-03-23
ES8505363A1 (es) 1985-05-16
PH19451A (en) 1986-04-18
IE840831L (en) 1984-10-06
JPH0465073B2 (el) 1992-10-16
PT78370B (en) 1986-05-28
NO841341L (no) 1984-10-08
DE124777T1 (de) 1985-06-05
AU2637584A (en) 1984-10-11
KR880002510B1 (ko) 1988-11-26
IL71432A (en) 1988-03-31
GR81903B (el) 1984-12-12
EP0124777B1 (en) 1986-10-29
PT78370A (en) 1984-05-01
ES531254A0 (es) 1985-05-16
DE3461086D1 (en) 1986-12-04
NO157575C (no) 1988-04-13
NO157575B (no) 1988-01-04
CA1262906C (en) 1989-11-14
AR245941A1 (es) 1994-03-30
DK179984A (da) 1984-10-07
EP0124777A1 (en) 1984-11-14
DK162442B (da) 1991-10-28
IL71432A0 (en) 1984-07-31
KR840009105A (ko) 1984-12-24
ATE23151T1 (de) 1986-11-15
US4529733A (en) 1985-07-16
CA1262906A (en) 1989-11-14
DK179984D0 (da) 1984-04-05
ZA842456B (en) 1984-11-28
NZ207716A (en) 1986-09-10

Similar Documents

Publication Publication Date Title
US4220649A (en) 1,4-Dihydropyridine-3,5-dicarboxylic acid ester derivatives
RU2036922C1 (ru) Производные 1,4-дигидропиридина или их гидрохлориды, обладающие антагонистическими свойствами по отношению к ионам кальция
CZ127396A3 (en) Short time acting dihydropyridines
Sunkel et al. Synthesis, platelet aggregation inhibitory activity, and in vivo antithrombotic activity of new 1, 4-dihydropyridines
FR2562892A1 (fr) Nouveaux dihydropyridinyldicarboxylates amides et esters, utilisation de ces composes comme medicament, compositions pharmaceutiques comprenant de tels composes et procede pour la preparation de tels composes
EP0124777B1 (en) 1,4-dihydropyridine derivatives
CA2433193C (en) Amide derivative of amlodipine
CA2433190C (en) Amlodipine hemimaleate
EP0160451B1 (en) Dihydropyridine-3,5-dicarboxylic acid ester derivative isomers, their preparation, and pharmaceutical compositions containing them
GB2137622A (en) 1,4-dihydropyridine derivatives
EP0154511A2 (en) Benzopyran racemates useful for treating cardiovascular diseases
JPS6352031B2 (el)
JP3049284B2 (ja) ヒダントイン誘導体並びにそれを有効成分とする糖尿病合併症及び循環器系疾患の予防及び治療剤
JP2002511451A (ja) アザシクロアルカン誘導体、その製造及び治療上の使用
EP0176053B1 (en) 1,4-dihydropyridine derivatives and pharmaceutical compositions containing them
AU2001100436A4 (en) Amlodipine hemimaleate
JPH04308575A (ja) ジヒドロピリジンアミド化合物
JPH05279255A (ja) 尿酸***促進剤
JPS6089420A (ja) 血管拡張剤
HU193784B (en) Process for producing dihydro-pyridine derivatives
JPH068296B2 (ja) アミノクロマノール誘導体
JPS6163689A (ja) ピリジン誘導体
JPS6092266A (ja) １，４−ジヒドロピリジン−３，５−ジカルボン酸ジエステル誘導体，その製造法及びそれを有効成分とする薬剤
SI21064A2 (sl) Amidni derivat amlodipina
JPH0251526B2 (el)

Legal Events

Date Code Title Description
MM4A Patent lapsed