HUP9800260A1 - Eljárás rekombináns adenovírus előállítására és génterápiai alkalmazása - Google Patents

Eljárás rekombináns adenovírus előállítására és génterápiai alkalmazása

Info

Publication number
HUP9800260A1
HUP9800260A1 HU9800260A HUP9800260A HUP9800260A1 HU P9800260 A1 HUP9800260 A1 HU P9800260A1 HU 9800260 A HU9800260 A HU 9800260A HU P9800260 A HUP9800260 A HU P9800260A HU P9800260 A1 HUP9800260 A1 HU P9800260A1
Authority
HU
Hungary
Prior art keywords
preparing
recombinant adenovirus
adenovirus genome
adenoviruses
production
Prior art date
Application number
HU9800260A
Other languages
English (en)
Inventor
Joël Crouzet
Laurent Naudin
Cécile Orsini
Emmanuelle Vigne
Patrice Yeh
Original Assignee
Rhone-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9476085&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9800260(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone-Poulenc Rorer S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of HUP9800260A1 publication Critical patent/HUP9800260A1/hu
Publication of HUP9800260A3 publication Critical patent/HUP9800260A3/hu
Publication of HU222808B1 publication Critical patent/HU222808B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány tárgya egy új eljárás rekőmbináns adenővírűselőállítására, és az adenővírűsők alkalmazása a génterápiában. Atalálmány az adenővírűsők előállítására fehasznált plazmidőkra isvőnatkőzik.ŕ
HU9800260A 1995-02-13 1996-02-09 Eljárás rekombináns adenovírusok előállítására, erre szolgáló prokariota plazmidok és az adenovírusokat tartalmazó gyógyszerkészítmények HU222808B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9501632A FR2730504B1 (fr) 1995-02-13 1995-02-13 Procede de preparation de genomes d'adenovirus recombinants
PCT/FR1996/000215 WO1996025506A1 (fr) 1995-02-13 1996-02-09 Procede de preparation de genome d'adenovirus recombinants

Publications (3)

Publication Number Publication Date
HUP9800260A1 true HUP9800260A1 (hu) 1998-05-28
HUP9800260A3 HUP9800260A3 (en) 2000-12-28
HU222808B1 HU222808B1 (hu) 2003-10-28

Family

ID=9476085

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800260A HU222808B1 (hu) 1995-02-13 1996-02-09 Eljárás rekombináns adenovírusok előállítására, erre szolgáló prokariota plazmidok és az adenovírusokat tartalmazó gyógyszerkészítmények

Country Status (19)

Country Link
US (1) US6261807B1 (hu)
EP (1) EP0809704B1 (hu)
JP (1) JP3842818B2 (hu)
KR (1) KR100575521B1 (hu)
AT (1) ATE405662T1 (hu)
AU (1) AU716777B2 (hu)
BR (1) BRPI9607583B8 (hu)
CA (1) CA2210956C (hu)
CZ (1) CZ294338B6 (hu)
DE (1) DE69637648D1 (hu)
FI (1) FI120046B (hu)
FR (1) FR2730504B1 (hu)
HU (1) HU222808B1 (hu)
IL (1) IL117115A (hu)
MX (1) MX9705937A (hu)
NO (1) NO327980B1 (hu)
SK (1) SK286965B6 (hu)
WO (1) WO1996025506A1 (hu)
ZA (1) ZA961153B (hu)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020136708A1 (en) * 1993-06-24 2002-09-26 Graham Frank L. System for production of helper dependent adenovirus vectors based on use of endonucleases
DE19620687A1 (de) * 1996-05-22 1997-11-27 Centeon Pharma Gmbh Neuer adenoviraler Vektor für den Transfer humaner Gene in vivo
ATE256196T1 (de) 1997-06-09 2003-12-15 Genvec Inc Chimäre vektoren, die die verpackungsregion eines phagengenoms und einen teil des genoms eines eukaryontischen virus enthalten
WO1999015686A1 (en) * 1997-09-23 1999-04-01 Genvec, Inc. Plasmids for construction of eukaryotic viral vectors
CN1342206A (zh) * 1998-08-28 2002-03-27 杜克大学 在IVa2,100K和/或preterminal protein序列上有缺失的腺病毒
JP2004501602A (ja) * 1999-02-18 2004-01-22 メルク　アンド　カンパニー　インコーポレイテッド エンドヌクレアーゼの使用に基づくヘルパー依存アデノウイルスベクターの生産のためのシステム
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
FR2799472B1 (fr) 1999-10-07 2004-07-16 Aventis Pharma Sa Preparation d'adenovirus recombinants et de banques adenovirales
US6998263B2 (en) 2000-02-09 2006-02-14 Genvec, Inc. Methods of preparing and using a viral vector library
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6573092B1 (en) 2000-10-10 2003-06-03 Genvec, Inc. Method of preparing a eukaryotic viral vector
AUPR518501A0 (en) 2001-05-22 2001-06-14 Unisearch Limited Yin yang-1
EP1453536A4 (en) 2001-12-12 2009-08-26 Mayne Pharma Int Pty Ltd COMPOSITION FOR PRESERVING VIRUSES
EP1697534B1 (en) 2003-12-01 2010-06-02 Life Technologies Corporation Nucleic acid molecules containing recombination sites and methods of using the same
DK2002003T3 (en) 2005-05-27 2016-03-21 Ospedale San Raffaele Srl Gene vector comprising miRNA
EP2147105B1 (en) 2007-05-02 2013-04-24 Merial Limited Dna plasmids having improved expression and stability
US20110269119A1 (en) * 2009-10-30 2011-11-03 Synthetic Genomics, Inc. Encoding text into nucleic acid sequences
AU2014338864C1 (en) * 2013-10-25 2020-07-16 Akamis Bio Limited Oncolytic adenoviruses armed with heterologous genes
US10076562B2 (en) 2016-04-19 2018-09-18 The Board Of Regents Of The University Of Texas System Methods for treating plague
WO2018054822A1 (en) 2016-09-20 2018-03-29 Boehringer Ingelheim Vetmedica Gmbh New swine influenza vaccine
NZ751966A (en) 2016-09-20 2023-03-31 Boehringer Ingelheim Vetmedica Gmbh New promoters
TWI817933B (zh) 2016-09-20 2023-10-11 德商百靈佳殷格翰維美迪加股份有限公司 新穎ehv***位點orf70
TW201823467A (zh) 2016-09-20 2018-07-01 德商百靈佳殷格翰維美迪加股份有限公司 犬腺病毒載體

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3532566B2 (ja) * 1993-06-24 2004-05-31 エル． グラハム，フランク 遺伝子治療のためのアデノウイルスベクター
SK282843B6 (sk) * 1993-07-13 2002-12-03 Rhone-Poulenc Rorer S. A. Defektný rekombinantný adenovírus a farmaceutický prostriedok s jeho obsahom
WO1995003400A1 (en) * 1993-07-23 1995-02-02 Johns Hopkins University School Of Medicine Recombinationally targeted cloning in yeast artificial chromosomes
FR2726285B1 (fr) * 1994-10-28 1996-11-29 Centre Nat Rech Scient Adenovirus depourvus de particules contaminantes viables, preparation et utilisation
DK0787200T3 (da) * 1994-10-28 2005-08-15 Univ Pennsylvania Forbedret adenovirus og fremgangsmåder til anvendelse heraf
FR2727689A1 (fr) * 1994-12-01 1996-06-07 Transgene Sa Nouveau procede de preparation d'un vecteur viral

Also Published As

Publication number Publication date
SK110097A3 (en) 1998-06-03
CA2210956C (fr) 2010-06-08
IL117115A0 (en) 1996-06-18
FI120046B (fi) 2009-06-15
JP3842818B2 (ja) 2006-11-08
MX9705937A (es) 1997-10-31
JPH11500007A (ja) 1999-01-06
CA2210956A1 (fr) 1996-08-22
AU716777B2 (en) 2000-03-09
NO327980B1 (no) 2009-11-02
NO973663L (no) 1997-08-08
BRPI9607583B8 (pt) 2016-11-08
BR9607583B1 (pt) 2009-12-01
HUP9800260A3 (en) 2000-12-28
HU222808B1 (hu) 2003-10-28
US6261807B1 (en) 2001-07-17
SK286965B6 (sk) 2009-08-06
AU4723596A (en) 1996-09-04
FI973309A (fi) 1997-08-12
CZ294338B6 (cs) 2004-12-15
KR19980702139A (ko) 1998-07-15
FR2730504A1 (fr) 1996-08-14
WO1996025506A1 (fr) 1996-08-22
NO973663D0 (no) 1997-08-08
BR9607583A (pt) 1998-07-07
IL117115A (en) 2005-06-19
ATE405662T1 (de) 2008-09-15
EP0809704B1 (fr) 2008-08-20
KR100575521B1 (ko) 2006-10-24
CZ255497A3 (en) 1997-11-12
ZA961153B (en) 1996-08-23
DE69637648D1 (de) 2008-10-02
FR2730504B1 (fr) 1997-03-28
EP0809704A1 (fr) 1997-12-03
FI973309A0 (fi) 1997-08-12

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Legal Events

Date Code Title Description
HFG4 Patent granted, date of granting

Effective date: 20030918

GB9A Succession in title

Owner name: AVENTIS PHARMA S.A., FR

Free format text: FORMER OWNER(S): RHONE-POULENC RORER S.A., FR; CENTELION, FR; GENCELL S.A., FR