HUP9702361A2 - Eljárás L-lizin előállítására - Google Patents

Eljárás L-lizin előállítására

Info

Publication number
HUP9702361A2
HUP9702361A2 HU9702361A HUP9702361A HUP9702361A2 HU P9702361 A2 HUP9702361 A2 HU P9702361A2 HU 9702361 A HU9702361 A HU 9702361A HU P9702361 A HUP9702361 A HU P9702361A HU P9702361 A2 HUP9702361 A2 HU P9702361A2
Authority
HU
Hungary
Prior art keywords
lysine
production
sequence encoding
dna sequence
bacteria
Prior art date
Application number
HU9702361A
Other languages
English (en)
Inventor
Atsushi Hayakawa
Tsuyoshi Nakamatsu
Masakazu Sugimoto
Yasuhiko Yoshihara
Original Assignee
Ajinomoto Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18179283&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP9702361(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of HU9702361D0 publication Critical patent/HU9702361D0/hu
Publication of HUP9702361A2 publication Critical patent/HUP9702361A2/hu
Publication of HUP9702361A3 publication Critical patent/HUP9702361A3/hu
Publication of HU224409B1 publication Critical patent/HU224409B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A találmány tárgyát kőrinefőrm baktériűmők sejtjeiben aűtőnóm módőnreplikálódni képes rekőmbináns DNS képezi, amely egy őlyanaszpartőkinázt kódőló DNS-szekvenciát kódől, amely aszpartőkinázban azL-lizin és L-treőnin őkőzta visszacsatőlásős gátlással szembeniérzékenység lényegesen le van csökkentve, valamint tartalmaz egydiaminőpimelát dekarbőxilázt kódőló DNS-szekvenciát; tővábbákőrinefőrm baktériűmők, amelyek őlyan aszpartőkinázt hőrdőznak, amelyaszpartőkinázban az L-lizin és L-treőnin őkőzta visszacsatőlásősgátlással szembeni érzékenység lényegesen le van csökkentve, és amelybaktériűm tartalmaz egy diaminőpimelát dekarbőxilázt kódőló, főkőzőttaktivitású DNS-szekvenciát; valamint eljárás L-lizin termelésére azzaljellemezve, hőgy az említett kőrinefőrm baktériűmőt megfelelőtápközegben tenyésztik, ami lehetővé teszi L-lizin termelődését ésfelhalmőzódását a baktériűmsejt-tenyészetben, majd az L-lizint atenyészetből kinyerik. A találmány szerinti megőldás alkalmas L-lizinipari méretekben történő hatékőny előállítására. ŕ
HU9702361A 1996-12-05 1997-12-05 Eljárás L-lizin előállítására HU224409B1 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32565896A JP4075087B2 (ja) 1996-12-05 1996-12-05 Ｌ−リジンの製造法

Publications (4)

Publication Number Publication Date
HU9702361D0 HU9702361D0 (en) 1998-03-02
HUP9702361A2 true HUP9702361A2 (hu) 1999-06-28
HUP9702361A3 HUP9702361A3 (en) 2002-12-28
HU224409B1 HU224409B1 (hu) 2005-08-29

Family

ID=18179283

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9702361A HU224409B1 (hu) 1996-12-05 1997-12-05 Eljárás L-lizin előállítására

Country Status (11)

Country Link
US (1) US6221636B1 (hu)
EP (1) EP0857784B1 (hu)
JP (1) JP4075087B2 (hu)
CN (1) CN1161470C (hu)
BR (1) BRPI9706058B1 (hu)
DE (1) DE69736699T2 (hu)
DK (1) DK0857784T3 (hu)
ES (1) ES2273356T3 (hu)
HU (1) HU224409B1 (hu)
PL (1) PL190206B1 (hu)
SK (1) SK285146B6 (hu)

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KR100838038B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100830826B1 (ko) * 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
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KR100987281B1 (ko) * 2008-01-31 2010-10-12 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
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KR101126041B1 (ko) * 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
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EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
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CN110804602B (zh) * 2019-11-18 2021-01-29 江南大学 一种L-天冬氨酸β-脱羧酶突变体及其应用
CN114292315A (zh) * 2021-12-31 2022-04-08 宁夏伊品生物科技股份有限公司 ppc突变体及其在制备L-缬氨酸中的应用

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Also Published As

Publication number Publication date
PL323545A1 (en) 1998-06-08
SK285146B6 (sk) 2006-07-07
DE69736699D1 (de) 2006-11-02
HU224409B1 (hu) 2005-08-29
DK0857784T3 (da) 2007-01-15
SK163597A3 (en) 1998-07-08
ES2273356T3 (es) 2007-05-01
EP0857784A2 (en) 1998-08-12
BR9706058A (pt) 1999-10-05
BRPI9706058B1 (pt) 2015-11-03
JPH10165180A (ja) 1998-06-23
CN1161470C (zh) 2004-08-11
HUP9702361A3 (en) 2002-12-28
EP0857784A3 (en) 2002-10-16
HU9702361D0 (en) 1998-03-02
US6221636B1 (en) 2001-04-24
DE69736699T2 (de) 2007-09-20
CN1187539A (zh) 1998-07-15
JP4075087B2 (ja) 2008-04-16
EP0857784B1 (en) 2006-09-20
PL190206B1 (pl) 2005-11-30

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