HUP0103883A2 - Új, késleltetett felszabadulású, orális készítmények - Google Patents
Új, késleltetett felszabadulású, orális készítményekInfo
- Publication number
- HUP0103883A2 HUP0103883A2 HU0103883A HUP0103883A HUP0103883A2 HU P0103883 A2 HUP0103883 A2 HU P0103883A2 HU 0103883 A HU0103883 A HU 0103883A HU P0103883 A HUP0103883 A HU P0103883A HU P0103883 A2 HUP0103883 A2 HU P0103883A2
- Authority
- HU
- Hungary
- Prior art keywords
- water
- component
- active substance
- sustained release
- oral formulations
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 abstract 1
- 239000002357 osmotic agent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
A találmány tárgya egy orális gyógyszerkészítmény, amely a hatóanyagotaz időben szabályozott módon adja le. A készítményben van egy elsőkomponens, amely tartalmaz egy első hatóanyagdózist, amelynek 70-95 %-át vízzel érintkezve 3-4 órán belül leadja és egy második komponens,amely tartalmaz egy második hatóanyagdózist, egy vízoldhatóozmotizálószert és egy vízben duzzadó kötőanyagot, ennek a másodikkomponensnek van egy vízáteresztő bevonata, amely az alkalmazás sorána vízzel érintkezve bizonyos késleltetési idő után felhasad, és ahatóanyagot kibocsátja. A találmány szerinti gyógyszerkészítményenyhén-közepesen súlyos Alzheimer-féle dementiában szenvedő betegekkezelésére alkalmazható. Ó
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9821299.6A GB9821299D0 (en) | 1998-10-01 | 1998-10-01 | Organic compounds |
GBGB9821298.8A GB9821298D0 (en) | 1998-10-01 | 1998-10-01 | Organic compoundsq |
GBGB9826654.7A GB9826654D0 (en) | 1998-12-03 | 1998-12-03 | Organic compounds |
GBGB9827624.9A GB9827624D0 (en) | 1998-12-16 | 1998-12-16 | Organic compounds |
GBGB9907822.2A GB9907822D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
GBGB9907823.0A GB9907823D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0103883A2 true HUP0103883A2 (hu) | 2002-05-29 |
HUP0103883A3 HUP0103883A3 (en) | 2002-11-28 |
Family
ID=27547321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103883A HUP0103883A3 (en) | 1998-10-01 | 1999-10-01 | New sustained release oral formulations |
Country Status (23)
Country | Link |
---|---|
US (5) | US20010033866A1 (hu) |
EP (1) | EP1121104B1 (hu) |
JP (1) | JP4012689B2 (hu) |
KR (1) | KR100603900B1 (hu) |
CN (1) | CN1406126A (hu) |
AT (1) | ATE286725T1 (hu) |
AU (1) | AU764866B2 (hu) |
BR (1) | BR9914251A (hu) |
CA (1) | CA2342340C (hu) |
CZ (1) | CZ302888B6 (hu) |
DE (1) | DE69923200T2 (hu) |
ES (1) | ES2237163T3 (hu) |
HK (1) | HK1052473A1 (hu) |
HU (1) | HUP0103883A3 (hu) |
ID (1) | ID27504A (hu) |
IL (2) | IL141762A0 (hu) |
NO (1) | NO331689B1 (hu) |
NZ (1) | NZ510683A (hu) |
PL (1) | PL196945B1 (hu) |
PT (1) | PT1121104E (hu) |
SK (1) | SK285250B6 (hu) |
TR (1) | TR200100931T2 (hu) |
WO (1) | WO2000019985A2 (hu) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9914251A (pt) * | 1998-10-01 | 2001-06-19 | Novartis Ag | Formulações orais de liberação sustentada |
EP1133230A4 (en) * | 1998-11-23 | 2004-05-26 | Bonnie M Davis | DOSAGE FORMULAS FOR ACETYLCHOLINESTERASE INHIBITORS |
CA2380333A1 (en) * | 1999-08-26 | 2001-03-01 | Christian Andina | Pharmaceutical formulations |
GB9923045D0 (en) * | 1999-09-29 | 1999-12-01 | Novartis Ag | New oral formulations |
AU2357202A (en) * | 2000-09-29 | 2002-04-08 | Solvay Pharm Bv | Ion-strength independent sustained release pharmaceutical formulation |
JP5023412B2 (ja) * | 2001-05-09 | 2012-09-12 | 吉澤石灰工業株式会社 | ホルムアルデヒド廃液の処理剤 |
DE60223695T2 (de) * | 2001-09-14 | 2008-10-30 | Scolr, Inc., Redmond | Aminosäure-modulierte dosierform mit verlängerter freisetzung |
JP2005525299A (ja) * | 2001-09-14 | 2005-08-25 | スコラー インコーポレイテッド | アミノ酸調節性の長期放出投薬形態 |
KR100453288B1 (ko) * | 2002-03-12 | 2004-10-21 | 한국화학연구원 | 약물의 제어 방출을 위한 스퀴즈-유형의 삼투성 약물 전달장치 |
PT1529116E (pt) * | 2002-08-07 | 2009-09-10 | Novartis Ag | Métodos para o tratamento da demência com base no genótipo da apo e |
ZA200508653B (en) * | 2003-04-07 | 2007-03-28 | Jurox Pty Ltd | Stable carprofen composition |
US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
US20060105036A1 (en) * | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
MEP3608A (en) * | 2003-08-08 | 2011-05-10 | Biovail Lab Int Srl | Modified-release tablet of bupropion hydrochloride |
US20100129310A1 (en) * | 2004-08-09 | 2010-05-27 | Pavak Rajnikanth Mehta | Stabilized desloratadine composition |
ES2403069T3 (es) * | 2005-02-22 | 2013-05-13 | Sun Pharma Advanced Research Company Ltd | Composición oral de liberación controlada que contiene levetiracetam |
CA2606740A1 (en) * | 2005-05-03 | 2006-11-09 | Mutual Pharmaceutical Company, Inc. | Quinine-containing controlled-release formulations |
CA2620594C (en) * | 2005-09-01 | 2012-08-21 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition having improved disintegratability |
GB0525461D0 (en) | 2005-12-15 | 2006-01-25 | Archimedes Dev Ltd | Pharmaceutical compositions |
GB0606562D0 (en) * | 2006-03-31 | 2006-05-10 | Novartis Ag | Organic compounds |
US7803778B2 (en) | 2006-05-23 | 2010-09-28 | Theracos, Inc. | Glucose transport inhibitors and methods of use |
US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
US8748419B2 (en) | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
BRPI0809607A2 (pt) | 2007-04-02 | 2014-09-30 | Theracos Inc | Composto, composição farmacêutica, combinação farmacêutica, e, método para tratar uma doença |
ITMI20071502A1 (it) * | 2007-07-25 | 2009-01-26 | Archimica Srl | Procedimento per la preparazione di formulazioni solide a rilascio controllato contenenti oxcarbazepina e formulazioni ottenibili con tale procedimento |
WO2009022345A1 (en) * | 2007-08-14 | 2009-02-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Phenyl carbamates for the treatment of multiple sclerosis |
BRPI0815708B8 (pt) | 2007-08-23 | 2021-05-25 | Theracos Sub Llc | composto, éster de pró-droga, composição farmacêutica, e, método para tratar uma doença ou condição |
US20100204303A1 (en) * | 2007-09-25 | 2010-08-12 | Idexx Laboratories, Inc. | Pharmaceutical Compositions for Administering Oligonucleotides |
US20110201597A1 (en) | 2008-03-27 | 2011-08-18 | Chase Thomas N | Method and composition for treating alzheimer-type dementia |
FR2931677B1 (fr) * | 2008-06-02 | 2010-08-20 | Sanofi Aventis | Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs |
US9061060B2 (en) | 2008-07-15 | 2015-06-23 | Theracos Inc. | Deuterated benzylbenzene derivatives and methods of use |
KR101654231B1 (ko) | 2008-08-22 | 2016-09-05 | 테라코스 서브, 엘엘씨 | Sglt2 억제제의 제조방법 |
CN102264743B (zh) | 2008-11-25 | 2015-02-11 | 罗彻斯特大学 | Mlk抑制剂及其使用方法 |
AU2010296044B2 (en) * | 2009-09-18 | 2015-05-14 | Chase Pharmaceuticals Corporation | Method and composition for treating Alzheimer-type dementia |
US20110150986A1 (en) * | 2009-12-18 | 2011-06-23 | Kristin Arnold | Quinine formulations, method of making, and metho of use thereof |
CN101797236B (zh) * | 2010-03-23 | 2012-05-23 | 西南大学 | 重酒石酸卡巴拉汀口腔崩解片及其制备方法 |
JP6086326B2 (ja) | 2010-05-24 | 2017-03-01 | ユニヴァーシティー オブ ロチェスター | 二環式ヘテロアリールキナーゼ阻害剤および使用方法 |
WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
WO2011153712A1 (en) | 2010-06-12 | 2011-12-15 | Theracos, Inc. | Crystalline form of benzylbenzene sglt2 inhibitor |
EP3502236B1 (en) | 2011-02-18 | 2023-08-23 | The Scripps Research Institute | Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate |
WO2012144463A1 (ja) | 2011-04-18 | 2012-10-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 腫瘍治療剤 |
TW201306881A (zh) * | 2011-05-06 | 2013-02-16 | Glaxosmithkline Llc | 緩釋對乙醯胺基酚調配物 |
BR112013029199B1 (pt) * | 2011-05-13 | 2022-02-08 | Eb Ip Hybritabs B.V. | Dispositivo de distribuição de dois fármacos |
US8524664B2 (en) | 2011-06-02 | 2013-09-03 | Colorado Seminary, Which owns and Operates The Univeristy of Denver | Methods of treating overproduction of cortisol using ACTH antagonist peptides |
US9945862B2 (en) | 2011-06-03 | 2018-04-17 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
JP6285865B2 (ja) | 2011-11-14 | 2018-02-28 | アルファシグマ ソシエタ ペル アチオニ | うつ病を有する対象のための処置レジメンを選択するためのアッセイ及び方法 |
KR20150048888A (ko) | 2012-09-05 | 2015-05-07 | 체이스 파마슈티칼스 코포레이션 | 항콜린 신경보호 조성물 및 그 방법 |
WO2014085795A1 (en) | 2012-11-30 | 2014-06-05 | University Of Rochester | Mixed lineage kinase inhibitors for hiv/aids therapies |
CN104755463A (zh) | 2012-12-21 | 2015-07-01 | 卫材R&D管理有限公司 | 非晶态形式的喹啉衍生物及其生产方法 |
US10517861B2 (en) | 2013-05-14 | 2019-12-31 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds |
ES2888074T3 (es) | 2013-08-16 | 2021-12-30 | Univ Maastricht | Tratamiento del deterioro cognitivo con inhibidor de PDE4 |
WO2015136446A1 (en) | 2014-03-11 | 2015-09-17 | Nestec S.A. | Methods for selecting antidepressant drug therapy to treat depression |
CN103877063A (zh) * | 2014-03-24 | 2014-06-25 | 张绪伟 | 一种重酒石酸卡巴拉汀胶囊及其制备方法 |
ES2926687T3 (es) | 2014-08-28 | 2022-10-27 | Eisai R&D Man Co Ltd | Derivado de quinolina muy puro y método para su producción |
PL3263106T3 (pl) | 2015-02-25 | 2024-04-02 | Eisai R&D Management Co., Ltd. | Sposób tłumienia goryczy pochodnej chinoliny |
WO2016140717A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharp & Dohme Corp. | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
KR101990951B1 (ko) * | 2015-04-27 | 2019-06-20 | 주식회사 네비팜 | 리바스티그민 함유 서방출 의약조성물 |
ES2886107T3 (es) | 2015-06-16 | 2021-12-16 | Prism Biolab Co Ltd | Antineoplásico |
IL243707A0 (en) | 2016-01-20 | 2016-05-01 | Galmed Res And Dev Ltd | Treatment to regulate the microbiota in the intestine |
KR20190021180A (ko) * | 2017-08-22 | 2019-03-05 | 아주대학교산학협력단 | 퇴행성 신경질환 치료용 복합 제형 조성물 |
KR20190036370A (ko) | 2017-09-27 | 2019-04-04 | 서원대학교산학협력단 | 약물의 서방성 제형을 위한 약물전달체 |
HRP20240162T1 (hr) | 2018-07-30 | 2024-04-12 | Biothea Pharma, Inc. | Kristalna sol epinefrin malonata |
CN112546037A (zh) * | 2020-12-08 | 2021-03-26 | 苏州大学 | 卡巴拉汀在制备抗辐射药中的应用 |
CN113398273B (zh) * | 2021-05-14 | 2022-07-19 | 广西壮族自治区中国科学院广西植物研究所 | 木聚糖衍生物作为亲水性缓释材料在制备药物缓释片中的应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014335A (en) * | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
USRE34990E (en) * | 1986-08-07 | 1995-07-04 | Ciba-Geigy Corporation | Oral therapeutic system having systemic action |
DE3805744C2 (de) * | 1987-03-04 | 1999-09-23 | Novartis Ag | Phenylcarbamate zur Hemmung der Acetylcholinesterase |
HU201906B (en) | 1987-03-04 | 1991-01-28 | Sandoz Ag | Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them |
DE3922167A1 (de) * | 1988-04-16 | 1991-01-17 | Sanol Arznei Schwarz Gmbh | Oral zu verabreichende diltiazemhydrochlorid enthaltende pharmazeutische zubereitung zur einmal taeglichen applikation und verfahren zu deren herstellung |
US5472710A (en) * | 1988-04-16 | 1995-12-05 | Schwarz Pharma Ag | Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture |
US5262173A (en) * | 1992-03-02 | 1993-11-16 | American Cyanamid Company | Pulsatile once-a-day delivery systems for minocycline |
US5260068A (en) * | 1992-05-04 | 1993-11-09 | Anda Sr Pharmaceuticals Inc. | Multiparticulate pulsatile drug delivery system |
EP0621032B1 (en) * | 1993-04-23 | 2000-08-09 | Novartis AG | Controlled release drug delivery device |
US5698224A (en) * | 1994-06-27 | 1997-12-16 | Alza Corporation | Tacrine therapy |
US5962535A (en) * | 1997-01-17 | 1999-10-05 | Takeda Chemical Industries, Ltd. | Composition for alzheimer's disease |
GB9701695D0 (en) | 1997-01-28 | 1997-03-19 | De Beers Ind Diamond | Insert for an abrasive tool |
DE19707655A1 (de) * | 1997-02-26 | 1998-08-27 | Hoechst Ag | Kombinationspräparat zur Anwendung bei Demenz |
ATE250929T1 (de) * | 1997-05-30 | 2003-10-15 | Osmotica Corp | Mehrlagige osmosevorrichtung |
GB9800526D0 (en) * | 1998-01-12 | 1998-03-11 | Ciba Geigy Ag | Organic compounds |
BR9914251A (pt) * | 1998-10-01 | 2001-06-19 | Novartis Ag | Formulações orais de liberação sustentada |
US6534541B1 (en) | 1999-10-19 | 2003-03-18 | Novartis Ag | Treatment of ocular disorders |
-
1999
- 1999-10-01 BR BR9914251-1A patent/BR9914251A/pt not_active Application Discontinuation
- 1999-10-01 PL PL348734A patent/PL196945B1/pl not_active IP Right Cessation
- 1999-10-01 SK SK439-2001A patent/SK285250B6/sk not_active IP Right Cessation
- 1999-10-01 CA CA002342340A patent/CA2342340C/en not_active Expired - Fee Related
- 1999-10-01 ID IDW20010671A patent/ID27504A/id unknown
- 1999-10-01 DE DE69923200T patent/DE69923200T2/de not_active Expired - Lifetime
- 1999-10-01 PT PT99950595T patent/PT1121104E/pt unknown
- 1999-10-01 WO PCT/EP1999/007298 patent/WO2000019985A2/en not_active Application Discontinuation
- 1999-10-01 NZ NZ510683A patent/NZ510683A/en not_active IP Right Cessation
- 1999-10-01 AU AU63321/99A patent/AU764866B2/en not_active Ceased
- 1999-10-01 KR KR1020017003384A patent/KR100603900B1/ko not_active IP Right Cessation
- 1999-10-01 ES ES99950595T patent/ES2237163T3/es not_active Expired - Lifetime
- 1999-10-01 CN CN99811633A patent/CN1406126A/zh active Pending
- 1999-10-01 EP EP99950595A patent/EP1121104B1/en not_active Expired - Lifetime
- 1999-10-01 IL IL14176299A patent/IL141762A0/xx unknown
- 1999-10-01 CZ CZ20011155A patent/CZ302888B6/cs not_active IP Right Cessation
- 1999-10-01 HU HU0103883A patent/HUP0103883A3/hu unknown
- 1999-10-01 TR TR2001/00931T patent/TR200100931T2/xx unknown
- 1999-10-01 AT AT99950595T patent/ATE286725T1/de active
- 1999-10-01 JP JP2000573347A patent/JP4012689B2/ja not_active Expired - Fee Related
-
2001
- 2001-03-01 IL IL141762A patent/IL141762A/en unknown
- 2001-03-22 NO NO20011471A patent/NO331689B1/no not_active IP Right Cessation
- 2001-03-27 US US09/818,690 patent/US20010033866A1/en not_active Abandoned
-
2002
- 2002-04-08 US US10/118,183 patent/US6565883B2/en not_active Expired - Fee Related
-
2003
- 2003-03-31 US US10/403,146 patent/US20030203025A1/en not_active Abandoned
- 2003-07-09 HK HK03104925.9A patent/HK1052473A1/zh unknown
-
2005
- 2005-04-14 US US11/105,967 patent/US20050175706A1/en not_active Abandoned
-
2006
- 2006-11-03 US US11/592,853 patent/US20070053982A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0103883A2 (hu) | Új, késleltetett felszabadulású, orális készítmények | |
DK1115384T3 (da) | Fentanyl-præparat til behandling af akutte smerter | |
ATE211385T1 (de) | Anwendungsformen zur behandlung der männlichen erektilen dysfunktion | |
HUP0301400A2 (hu) | Gyógyszerösszetétel és adagolási forma az alendronát és/vagy más biszfoszfonátoknak a gyomorban történż késleltetett felszabadulására | |
HK1046244A1 (en) | Controlled release and taste masking oral pharmaceutical compositions. | |
HUP0401714A2 (hu) | Propiverin vagy gyógyászatilag elfogadható sóinak nyújtott hatóanyag-eladású, orális adagolási formái | |
AP1748A (en) | Chronotherapeutic dosage forms. | |
IS2156B (is) | Settar bensensúlfonamíðafleiður sem forlyf fyrir COX-2 tálma, aðferð til þess að búa þær til, lyfjasamsetningar sem innihalda þær og notkun þeirra við framleiðslu lyfja | |
RS56252B1 (sr) | Jednodnevne formulacije oksikodona | |
HUP0301591A2 (hu) | Szabályozott hatóanyag-leadású hidrokodon-készítmények | |
DK0949925T3 (da) | Flad lægemiddelform til anbringelse i mundhulen med frigivelse der af buprenorphin eller et farmakologisk sammenligneligt stof, samt fremgangsmåde til fremstilling deraf | |
TR199903280T2 (xx) | Sertralin tuzlar� ve sertralinin tutmal�-bo�altma dozaj bi�imleri. | |
ATE345782T1 (de) | Dosierungsformen enthaltend geschmacksmaskierten wirkstoffen | |
ATE302588T1 (de) | Dentales produkt gegen zahnstein und betreffende methode | |
HUP0102206A2 (hu) | Delavirdint tartalmazó tabletta formájú készítmény | |
HUP9901794A2 (hu) | Protonpumpa inhibitorok új beadási formája | |
SE0300831D0 (sv) | New formulations and use therof | |
HUP9801227A2 (hu) | Monoamin-oxidáz B inhibitorokból álló gyógyászati készítmények és alkalmazásuk | |
HUP0103454A2 (hu) | Entacapont vagy nitecapont és keresztkötésű cellulózszármazékot tartalmazó gyógyászati készítmény | |
HUP0401308A2 (hu) | Folyékony polimer kompozíció szájüregi betegségek megelőzésére és kezelésére | |
DK1345595T3 (da) | Ionstyrke-uafhængig farmaceutisk formulering med depotfrigivelse | |
RS49599B (sr) | Upotreba inhibitora h+, k+-atp-aze i glukokortikoida i farmaceutska formulacija | |
HUP0001104A2 (hu) | Ibuprofent és domperidont tartalmazó készítmények migrén kezelésére | |
HUP0204417A2 (en) | Oral ciprofloxacin-composition of controlled release | |
WO2002096870A3 (en) | Sponge-derived terpenoids and methods of use |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |