HUE051074T2 - 3,5-diszubsztituált benzol alkinil vegyület kristálya - Google Patents
3,5-diszubsztituált benzol alkinil vegyület kristályaInfo
- Publication number
- HUE051074T2 HUE051074T2 HUE16773207A HUE16773207A HUE051074T2 HU E051074 T2 HUE051074 T2 HU E051074T2 HU E16773207 A HUE16773207 A HU E16773207A HU E16773207 A HUE16773207 A HU E16773207A HU E051074 T2 HUE051074 T2 HU E051074T2
- Authority
- HU
- Hungary
- Prior art keywords
- crystal
- disubstituted benzene
- alkynyl compound
- benzene alkynyl
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
- C30B29/54—Organic compounds
- C30B29/58—Macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015070927 | 2015-03-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE051074T2 true HUE051074T2 (hu) | 2021-03-01 |
Family
ID=57006122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16773207A HUE051074T2 (hu) | 2015-03-31 | 2016-03-31 | 3,5-diszubsztituált benzol alkinil vegyület kristálya |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US10434103B2 (hu) |
| EP (1) | EP3279202B1 (hu) |
| JP (2) | JP6190079B2 (hu) |
| KR (1) | KR101917557B1 (hu) |
| CN (2) | CN111393446B (hu) |
| AU (1) | AU2016240841C1 (hu) |
| BR (1) | BR112017019809A2 (hu) |
| CA (1) | CA2980888C (hu) |
| DK (1) | DK3279202T3 (hu) |
| ES (1) | ES2812785T3 (hu) |
| HK (1) | HK1246297A1 (hu) |
| HU (1) | HUE051074T2 (hu) |
| MX (1) | MX2017012568A (hu) |
| MY (1) | MY196077A (hu) |
| PH (1) | PH12017501690A1 (hu) |
| PL (1) | PL3279202T3 (hu) |
| PT (1) | PT3279202T (hu) |
| RU (1) | RU2672563C1 (hu) |
| SG (1) | SG11201707384YA (hu) |
| WO (1) | WO2016159327A1 (hu) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3023100T3 (pl) | 2013-07-18 | 2019-07-31 | Taiho Pharmaceutical Co., Ltd. | Lek przeciwnowotworowy do okresowego podawania inhibitora FGFR |
| US10124003B2 (en) | 2013-07-18 | 2018-11-13 | Taiho Pharmaceutical Co., Ltd. | Therapeutic agent for FGFR inhibitor-resistant cancer |
| CN111393446B (zh) | 2015-03-31 | 2022-12-20 | 大鹏药品工业株式会社 | 3,5-二取代的苯炔基化合物晶体 |
| US11883404B2 (en) | 2016-03-04 | 2024-01-30 | Taiho Pharmaceuticals Co., Ltd. | Preparation and composition for treatment of malignant tumors |
| CA3094431C (en) | 2018-03-19 | 2023-06-27 | Taiho Pharmaceutical Co., Ltd. | Pharmaceutical composition including sodium alkyl sulfate |
| WO2020096050A1 (ja) | 2018-11-09 | 2020-05-14 | 大鵬薬品工業株式会社 | ジメトキシベンゼン化合物の類縁物質、該化合物の分析方法及び標準品 |
| AU2018448845B2 (en) | 2018-11-09 | 2022-03-24 | Taiho Pharmaceutical Co., Ltd. | Method for producing dimethoxybenzene compound |
| TWI791928B (zh) * | 2018-11-26 | 2023-02-11 | 日商大鵬藥品工業股份有限公司 | 透過併用纖維母細胞生長因子受體抑制劑與內分泌療法來治療及預防可適用內分泌療法之腫瘤的方法 |
| WO2020170355A1 (ja) * | 2019-02-20 | 2020-08-27 | 大鵬薬品工業株式会社 | Ｆｇｆｒ１変異腫瘍の治療方法 |
| CN114127051A (zh) * | 2019-05-17 | 2022-03-01 | 金耐特生物制药公司 | 成纤维细胞生长因子受体激酶的抑制剂 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE533770T1 (de) | 2005-10-06 | 2011-12-15 | Schering Corp | Pyrazolopyrimidine als proteinkinaseinhibitoren |
| CA2755268C (en) | 2005-11-15 | 2013-12-31 | Array Biopharma, Inc. | Erbb inhibitors |
| US7659274B2 (en) | 2006-01-25 | 2010-02-09 | Osi Pharmaceuticals, Inc. | Unsaturated mTOR inhibitors |
| EP1939197A1 (en) | 2006-12-22 | 2008-07-02 | Schwarz Pharma Ag | 8-ethinylxanthine derivatives as selective A2A receptor antagonists |
| EP2560007A1 (en) | 2007-03-28 | 2013-02-20 | Pharmacyclics, Inc. | Identification of bruton's tyrosine kinase inhibitors |
| KR20110020904A (ko) | 2008-06-19 | 2011-03-03 | 아스트라제네카 아베 | 피라졸 화합물 436 |
| GB0819105D0 (en) | 2008-10-17 | 2008-11-26 | Chroma Therapeutics Ltd | Pyrrolo-pyrimidine compounds |
| AU2010243353B2 (en) | 2009-04-30 | 2014-09-11 | Astex Therapeutics Limited | Imidazole derivatives and their use as modulators of Cyclin dependent Kinases |
| KR101483215B1 (ko) | 2010-01-29 | 2015-01-16 | 한미약품 주식회사 | 단백질 키나아제 저해활성을 갖는 비시클릭 헤테로아릴 유도체 |
| EP2547698B1 (en) | 2010-03-14 | 2015-07-29 | The Translational Genomics Research Institute | Methods of determining susceptibility of tumors to tyrosine kinase inhibitors |
| DE102011015188A1 (de) | 2010-03-29 | 2011-09-29 | Herbert Kannegiesser Gmbh | Verfahren zur Nassbehandlung, insbesondere zum Reinigen, von Gegenständen |
| WO2011153514A2 (en) | 2010-06-03 | 2011-12-08 | Pharmacyclics, Inc. | The use of inhibitors of bruton's tyrosine kinase (btk) |
| EP2698372B1 (en) | 2011-04-06 | 2016-02-03 | Taiho Pharmaceutical Co., Ltd. | Novel imidazo-oxazine compound or salt thereof |
| SG2014009286A (en) | 2012-01-19 | 2014-04-28 | Taiho Pharmaceutical Co Ltd | 3,5-disubstituted alkynylbenzene compound and salt thereof |
| WO2013125709A1 (ja) * | 2012-02-23 | 2013-08-29 | 大鵬薬品工業株式会社 | キノリルピロロピリミジル縮合環化合物又はその塩 |
| CN103570725B (zh) | 2012-08-01 | 2017-03-22 | 中国科学院上海药物研究所 | 哌嗪并***类化合物及其制备方法和用途 |
| US9925240B2 (en) | 2013-03-06 | 2018-03-27 | Genentech, Inc. | Methods of treating and preventing cancer drug resistance |
| PE20152033A1 (es) | 2013-04-19 | 2016-01-21 | Incyte Holdings Corp | Heterociclos bicicliclos como inhibidores de fgfr |
| US10124003B2 (en) | 2013-07-18 | 2018-11-13 | Taiho Pharmaceutical Co., Ltd. | Therapeutic agent for FGFR inhibitor-resistant cancer |
| PL3023100T3 (pl) * | 2013-07-18 | 2019-07-31 | Taiho Pharmaceutical Co., Ltd. | Lek przeciwnowotworowy do okresowego podawania inhibitora FGFR |
| AU2015250574B2 (en) | 2014-04-25 | 2020-07-16 | Chugai Seiyaku Kabushiki Kaisha | Preparation containing tetracyclic compound at high dose |
| CN111393446B (zh) | 2015-03-31 | 2022-12-20 | 大鹏药品工业株式会社 | 3,5-二取代的苯炔基化合物晶体 |
| KR20240014585A (ko) | 2016-03-04 | 2024-02-01 | 다이호야쿠힌고교 가부시키가이샤 | 악성 종양 치료용 제제 및 조성물 |
-
2016
- 2016-03-31 CN CN202010284155.8A patent/CN111393446B/zh active Active
- 2016-03-31 WO PCT/JP2016/060844 patent/WO2016159327A1/ja active Application Filing
- 2016-03-31 BR BR112017019809-6A patent/BR112017019809A2/pt active IP Right Grant
- 2016-03-31 ES ES16773207T patent/ES2812785T3/es active Active
- 2016-03-31 EP EP16773207.2A patent/EP3279202B1/en active Active
- 2016-03-31 HU HUE16773207A patent/HUE051074T2/hu unknown
- 2016-03-31 MX MX2017012568A patent/MX2017012568A/es active IP Right Grant
- 2016-03-31 US US15/562,455 patent/US10434103B2/en active Active
- 2016-03-31 SG SG11201707384YA patent/SG11201707384YA/en unknown
- 2016-03-31 AU AU2016240841A patent/AU2016240841C1/en active Active
- 2016-03-31 CA CA2980888A patent/CA2980888C/en active Active
- 2016-03-31 RU RU2017134584A patent/RU2672563C1/ru active
- 2016-03-31 PT PT167732072T patent/PT3279202T/pt unknown
- 2016-03-31 CN CN201680019829.3A patent/CN107406455B/zh active Active
- 2016-03-31 PL PL16773207T patent/PL3279202T3/pl unknown
- 2016-03-31 KR KR1020177030951A patent/KR101917557B1/ko active IP Right Grant
- 2016-03-31 JP JP2016566309A patent/JP6190079B2/ja active Active
- 2016-03-31 DK DK16773207.2T patent/DK3279202T3/da active
- 2016-03-31 MY MYPI2017703525A patent/MY196077A/en unknown
-
2017
- 2017-08-02 JP JP2017149671A patent/JP2017193581A/ja active Pending
- 2017-09-15 PH PH12017501690A patent/PH12017501690A1/en unknown
-
2018
- 2018-05-08 HK HK18105931.1A patent/HK1246297A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12017501690A1 (en) | 2018-03-19 |
| CN111393446B (zh) | 2022-12-20 |
| EP3279202A1 (en) | 2018-02-07 |
| CN111393446A (zh) | 2020-07-10 |
| EP3279202A4 (en) | 2018-08-22 |
| EP3279202B1 (en) | 2020-06-24 |
| WO2016159327A1 (ja) | 2016-10-06 |
| KR101917557B1 (ko) | 2018-11-09 |
| AU2016240841C1 (en) | 2018-05-17 |
| CN107406455B (zh) | 2020-05-12 |
| JP6190079B2 (ja) | 2017-08-30 |
| RU2672563C1 (ru) | 2018-11-16 |
| CA2980888A1 (en) | 2016-10-06 |
| US10434103B2 (en) | 2019-10-08 |
| MX2017012568A (es) | 2018-01-25 |
| MY196077A (en) | 2023-03-13 |
| BR112017019809A2 (pt) | 2018-05-29 |
| SG11201707384YA (en) | 2017-10-30 |
| ES2812785T3 (es) | 2021-03-18 |
| JPWO2016159327A1 (ja) | 2017-04-27 |
| KR20170132251A (ko) | 2017-12-01 |
| AU2016240841B2 (en) | 2018-02-01 |
| HK1246297A1 (zh) | 2018-09-07 |
| PL3279202T3 (pl) | 2020-12-28 |
| CN107406455A (zh) | 2017-11-28 |
| JP2017193581A (ja) | 2017-10-26 |
| CA2980888C (en) | 2018-03-06 |
| AU2016240841A1 (en) | 2017-10-05 |
| DK3279202T3 (da) | 2020-08-17 |
| PT3279202T (pt) | 2020-08-31 |
| US20180110782A1 (en) | 2018-04-26 |
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