HUE041471T2 - Rezolvinok: Biotemplátok terápiás beavatkozásokhoz - Google Patents

Rezolvinok: Biotemplátok terápiás beavatkozásokhoz

Info

Publication number
HUE041471T2
HUE041471T2 HUE09009237A HUE09009237A HUE041471T2 HU E041471 T2 HUE041471 T2 HU E041471T2 HU E09009237 A HUE09009237 A HU E09009237A HU E09009237 A HUE09009237 A HU E09009237A HU E041471 T2 HUE041471 T2 HU E041471T2
Authority
HU
Hungary
Prior art keywords
dha
epa
resolvins
present
compounds
Prior art date
Application number
HUE09009237A
Other languages
English (en)
Inventor
Charles Serhan
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Publication of HUE041471T2 publication Critical patent/HUE041471T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
HUE09009237A 2002-08-12 2003-08-12 Rezolvinok: Biotemplátok terápiás beavatkozásokhoz HUE041471T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40279802P 2002-08-12 2002-08-12
US10/639,714 US7585856B2 (en) 2002-08-12 2003-08-12 Resolvins: Biotemplates for novel therapeutic interventions

Publications (1)

Publication Number Publication Date
HUE041471T2 true HUE041471T2 (hu) 2019-05-28

Family

ID=31720623

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE09009237A HUE041471T2 (hu) 2002-08-12 2003-08-12 Rezolvinok: Biotemplátok terápiás beavatkozásokhoz

Country Status (12)

Country Link
US (3) US7585856B2 (hu)
EP (3) EP1537067B1 (hu)
JP (7) JP4845378B2 (hu)
AT (1) ATE449057T1 (hu)
AU (2) AU2003258194B2 (hu)
CA (1) CA2495260C (hu)
DE (1) DE60330154D1 (hu)
DK (1) DK2216318T3 (hu)
ES (1) ES2700133T3 (hu)
HU (1) HUE041471T2 (hu)
SI (1) SI2216318T1 (hu)
WO (1) WO2004014835A2 (hu)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3846801A (en) 2000-02-16 2001-08-27 Brigham & Womens Hospital Aspirin-triggered lipid mediators
EP1268393A2 (en) 2000-03-20 2003-01-02 Trustees Of Boston University Lipoxin analogs and methods for the treatment of periodontal disease
US7582785B2 (en) * 2002-04-01 2009-09-01 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
US7902257B2 (en) 2002-04-01 2011-03-08 University Of Southern California Trihydroxy polyunsaturated eicosanoid
US8481772B2 (en) 2002-04-01 2013-07-09 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
US7759395B2 (en) * 2002-08-12 2010-07-20 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
ES2700133T3 (es) * 2002-08-12 2019-02-14 Brigham & Womens Hospital Resolvinas: modelos biológicos para intervenciones terapéuticas
WO2004078143A2 (en) * 2003-03-05 2004-09-16 The Brigham And Women's Hospital Inc. Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs
WO2005105025A1 (en) * 2004-04-14 2005-11-10 Boston University Methods and compositions for preventing or treating periodontal diseases
US7884131B2 (en) * 2004-11-19 2011-02-08 Martek Biosciences, Corporation Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same
US7893106B2 (en) * 2004-11-19 2011-02-22 Martek Biosciences, Corporation Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same
US20090318394A1 (en) * 2004-11-19 2009-12-24 Julie Nauroth Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same
US20060293288A1 (en) * 2005-01-07 2006-12-28 Serhan Charles N Use of resolvins to treat gastrointestinal diseases
WO2007041440A2 (en) * 2005-10-03 2007-04-12 The Brigham And Women's Hospital, Inc. Anti-inflammatory actions of neuroprotectin d1/protectin d1 and its natural stereoisomers
US8636986B2 (en) * 2005-11-18 2014-01-28 The Forsyth Institute Treatment and prevention of bone loss using resolvins
EP1983977A4 (en) * 2006-01-31 2011-11-30 Martek Biosciences Corp OXYLIPINES FROM STEARIDONIC ACID AND GAMMA-LINOLIC ACID AND METHOD FOR THE PRODUCTION AND USE THEREOF
US20070254897A1 (en) * 2006-04-28 2007-11-01 Resolvyx Pharmaceuticals, Inc. Compositions and methods for the treatment of cardiovascular disease
RU2009101324A (ru) * 2006-07-19 2010-07-27 Ризолвикс Фармасьютикалз, Инк. (Us) Композиции и способы лечения воспаления слизистой оболочки
WO2008063772A2 (en) * 2006-10-13 2008-05-29 The Brigham And Women's Hospital Inc. Resolvin d series and protectin d1 mitigate acute kidney injury
WO2008058274A2 (en) * 2006-11-09 2008-05-15 Children's Medical Center Corporation Use of resolvins and docosatrienes and analogues thereof for the treatment of angiogenesis and ocular neovascularization
US20100048705A1 (en) * 2006-11-09 2010-02-25 Children's Medical Center Corporation Methods of treating and preventing neovascularization with omega-3 polyunsaturated fatty acids
EP2120920A4 (en) * 2007-02-20 2011-06-15 Martek Biosciences Corp OXYLIPINES OF LONG-CHAIN MULTIPLE-UNSATURATED FATTY ACIDS AND METHOD FOR THEIR PREPARATION AND USE
US20110027841A1 (en) * 2007-12-21 2011-02-03 Martek Biosciences Corporation Method for preparation of oxylipins
US20110237495A1 (en) * 2008-05-21 2011-09-29 The Brigham And Women's Hospital, Inc. Corporate Sponsored Research And Licensing Functional metabolomics coupled microfluidic chemotaxis device and identification of novel cell mediators
ES2569371T3 (es) 2008-09-16 2016-05-10 The Brigham And Women's Hospital Inc. Compuestos del ácido 7,14-dihidroxidocosahexaenoico
EP2415748A4 (en) 2009-02-20 2013-08-07 Univ Tokyo NEW INFLAMMATORY COMPOUNDS
WO2012170791A2 (en) * 2011-06-10 2012-12-13 The Brigham And Women's Hospital, Inc. Docosahexaenoyl ethanolamides
EP2887923B1 (en) 2012-08-24 2023-04-05 Sun Pharmaceutical Industries Limited Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions
US9463177B2 (en) 2012-09-10 2016-10-11 The Regents Of The University Of California Compounds and methods for modulating vascular injury
CN103588670A (zh) * 2013-10-28 2014-02-19 史克勇 一种癌痛药物
CN103601649A (zh) * 2013-10-28 2014-02-26 史克勇 新型化合物
CN103588671A (zh) * 2013-10-28 2014-02-19 史克勇 癌性疼痛治疗药物
CN103588673A (zh) * 2013-10-29 2014-02-19 史克勇 癌痛药物
FR3029836B1 (fr) * 2014-12-11 2016-12-23 Saint Gobain Feuillete d'une feuille de materiau polymere epais et d'une feuille de verre mince
WO2016149582A1 (en) 2015-03-18 2016-09-22 The Forsyth Institute Methods for stabilizing atherosclerotic plaques using lipoxins, resolvins, and analogs thereof
ES2607715B1 (es) * 2015-10-01 2018-01-17 Solutex Na, Lcc Proceso para la preparación y estabilización de emulsiones con omega-3 mediante redes cristalinas isométricas de derivados de celulosa
DK3373976T3 (da) 2015-11-10 2024-04-02 Sun Pharmaceutical Ind Ltd Topiske formuleringer og anvendelser deraf
US11903998B2 (en) 2016-05-27 2024-02-20 Forsyth Dental Infirmary For Children Compositions and methods of treating cancer using lipid agonists and receptors thereof
JP2022504834A (ja) 2018-10-09 2022-01-13 ユニバーシティ オブ ロチェスター 外陰膣障害の治療
JP7220940B2 (ja) * 2020-02-18 2023-02-13 国立大学法人北海道大学 レゾルビンe2の安定等価体
WO2023137554A1 (en) * 2022-01-20 2023-07-27 Benderdour Mohamed Resolvin analogs compounds, methods and uses thereof
WO2023168245A2 (en) 2022-03-03 2023-09-07 Thetis Pharmaceuticals Llc Cyclodextrin complexes of specialized proresolving mediators

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201211A (en) * 1977-07-12 1980-05-06 Alza Corporation Therapeutic system for administering clonidine transdermally
GB2033745B (en) 1978-05-26 1983-08-17 Wellcome Found Fatty acid and derivatives thereof for use in treatment or prophylaxis of thromboembolic conditions
US4442099A (en) * 1981-11-27 1984-04-10 Research Corporation Leukotriene analogues
US4567290A (en) * 1981-11-27 1986-01-28 Research Corporation Leukotriene analogues
US4576758A (en) * 1984-06-01 1986-03-18 The Upjohn Company Anti-inflammatory lipoxin B analogs
US4759880A (en) * 1984-09-27 1988-07-26 Research Corporation Alkanoarachidonic acids
GB8507058D0 (en) * 1985-03-19 1985-04-24 Efamol Ltd Pharmaceutical & dietary compositions
US4710521A (en) * 1986-07-25 1987-12-01 The Celotex Corporation Catalyst mixtures for polyisocyanurate foam
US4810424A (en) 1987-10-09 1989-03-07 The State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Method for the recovery of 12-(S)-hydroxyeicosapentaenoic acid from the red alga murrayella periclados
US5136501A (en) * 1989-05-26 1992-08-04 Reuters Limited Anonymous matching system
JPH06505959A (ja) * 1990-05-07 1994-07-07 ボッコー バリー アイ 安定な脱臭油及びその医薬組成物の方法及び製剤
US5650435A (en) * 1991-04-01 1997-07-22 Madara; James L. Modulation of inflammation related to columnar epithelia
US5087790A (en) * 1991-06-12 1992-02-11 University Of Southern California Method for olefination of carbonyl compounds using titanocene derivatives
EP0591303B1 (en) * 1991-06-24 2000-12-06 Women's And Children's Hospital Methods and compositions for treating malaria and other diseases
US5177046A (en) * 1991-09-20 1993-01-05 Air Products And Chemicals, Inc. Amine-boron adducts as reduced odor catalyst compositions for the production of polyurethanes
JPH05186342A (ja) 1992-01-10 1993-07-27 Fujirebio Inc 免疫調節作用を併せもつ抗炎症剤
US5409955A (en) 1993-05-13 1995-04-25 Bockow; Barry I. Compositions and methods for inhibiting uterine contractility
US6048897A (en) * 1993-06-15 2000-04-11 Brigham And Women's Hospital Lipoxin compounds and their use in treating cell proliferative disorders
US5441951A (en) * 1994-06-15 1995-08-15 Brigham & Women's Hospital Lipoxin compounds
US6887901B1 (en) * 1993-06-15 2005-05-03 Brigham & Women's Hospital, Inc. Lipoxin compounds and their use in treating cell proliferative disorders
US5411988A (en) * 1993-10-27 1995-05-02 Bockow; Barry I. Compositions and methods for inhibiting inflammation and adhesion formation
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
US6030917A (en) * 1996-07-23 2000-02-29 Symyx Technologies, Inc. Combinatorial synthesis and analysis of organometallic compounds and catalysts
US5752238A (en) * 1994-11-03 1998-05-12 Intel Corporation Consumer-driven electronic information pricing mechanism
US5594732A (en) * 1995-03-03 1997-01-14 Intecom, Incorporated Bridging and signalling subsystems and methods for private and hybrid communications systems including multimedia systems
US5845265A (en) * 1995-04-26 1998-12-01 Mercexchange, L.L.C. Consignment nodes
US5756789A (en) * 1995-06-08 1998-05-26 Texaco, Inc. Synthesis of metal--containing aluminophosphates with layered structure
CA2182851A1 (en) 1995-08-15 1997-02-16 August Masaru Watanabe Method for treating substance abuse withdrawal
US5709855A (en) 1995-09-22 1998-01-20 Bockow; Barry I. Compositions of spirulina algae and omega fatty acids for treatment of inflammation and pain
US5870717A (en) * 1995-11-13 1999-02-09 International Business Machines Corporation System for ordering items over computer network using an electronic catalog
TR199802049T2 (xx) * 1996-04-12 1999-01-18 G.D.Searle & Co. COX-2 Inhibit�rlerinin �nilac� olarak s�bstit�e edilmi� benzens�lfonamid t�revleri.
US5878400A (en) * 1996-06-17 1999-03-02 Trilogy Development Group, Inc. Method and apparatus for pricing products in multi-level product and organizational groups
US5842040A (en) * 1996-06-18 1998-11-24 Storage Technology Corporation Policy caching method and apparatus for use in a communication device based on contents of one data unit in a subset of related data units
DE69739048D1 (de) * 1996-06-28 2008-11-27 Univ Southern California Verfahren zur synthese von aminen und aminosäuren mit organoborverbindungen
US5890138A (en) * 1996-08-26 1999-03-30 Bid.Com International Inc. Computer auction system
US5861399A (en) 1996-07-17 1999-01-19 Heart Care Partners Methods and compositions for the rapid and enduring relief of inadequate myocardial function
US5896379A (en) * 1996-08-26 1999-04-20 Motorola, Inc. Network node for packet switching with selective data processing and method therefor
US5912006A (en) 1996-08-28 1999-06-15 Eboc, Inc. Compositions and methods for alleviating discomforting menstrual pain
US5946467A (en) * 1996-09-20 1999-08-31 Novell, Inc. Application-level, persistent packeting apparatus and method
US20020055539A1 (en) 1996-10-02 2002-05-09 Bockow Barry I. Compositions and methods for treating cardiovascular conditions
US6201022B1 (en) 1997-03-27 2001-03-13 Myorx, Inc. Methods for treating neurotransmitter-mediated pain syndromes by topically administering an omega fatty acid
US6008205A (en) * 1997-04-04 1999-12-28 The Brigham & Women's Hospital, Inc. Polyisoprenyl phosphate stable analogs for regulation of neutrophil responses
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US6428990B1 (en) 1997-04-11 2002-08-06 Abbott Laboratories Human desaturase gene and uses thereof
US5878423A (en) * 1997-04-21 1999-03-02 Bellsouth Corporation Dynamically processing an index to create an ordered set of questions
US6030715A (en) * 1997-10-09 2000-02-29 The University Of Southern California Azlactone-related dopants in the emissive layer of an OLED
US6259699B1 (en) * 1997-12-30 2001-07-10 Nexabit Networks, Llc System architecture for and method of processing packets and/or cells in a common switch
JP3196714B2 (ja) * 1998-03-05 2001-08-06 日本電気株式会社 トリプルウェル構造の半導体集積回路の製造方法
JP2002513750A (ja) 1998-05-07 2002-05-14 エラン コーポレーシヨン ピーエルシー 溶媒/助溶剤を含まないマイクロエマルジョン及びエマルジョンプレ濃縮物のドラッグデリバリーシステム
US6377937B1 (en) * 1998-05-28 2002-04-23 Paskowitz Associates Method and system for more effective communication of characteristics data for products and services
US6069109A (en) * 1998-07-01 2000-05-30 Union Carbide Chemicals & Plastics Technology Corporation Process for the production of half-sandwich transition metal based catalyst precursors
US6336138B1 (en) * 1998-08-25 2002-01-01 Hewlett-Packard Company Template-driven approach for generating models on network services
AU1321700A (en) * 1998-10-23 2000-05-15 University Of Southern California Combinatorial approach to chiral reagents or catalysts having amine or amino alcohol ligands
US6336105B1 (en) * 1998-11-16 2002-01-01 Trade Access Inc. System and method for representing data and providing electronic non-repudiation in a negotiations system
DE19855426A1 (de) 1998-12-02 2000-06-08 Wolfgang Langhoff Mittel zur Therapie und Prophylaxe von rheumatisch-arthritischen Erkrankungen und zur Prophylaxe von cardiovaskulären Erkrankungen
US6272474B1 (en) * 1999-02-08 2001-08-07 Crisostomo B. Garcia Method for monitoring and trading stocks via the internet displaying bid/ask trade bars
US6397212B1 (en) * 1999-03-04 2002-05-28 Peter Biffar Self-learning and self-personalizing knowledge search engine that delivers holistic results
CA2645558C (en) * 1999-03-18 2012-05-15 Brigham And Women's Hospital Regulation of phospholipase d activity
DK1163204T3 (da) * 1999-03-18 2005-12-19 Brigham & Womens Hospital Lipoxinforbindelser og deres anvendelse
CA2367160A1 (en) * 1999-03-18 2000-09-21 Charles N. Serhan Leukotriene b4 receptor transgenic mammals
AU775140B2 (en) * 1999-03-18 2004-07-22 Brigham And Women's Hospital Use of lipoxin compounds for inhibiting of TNF-(alfa) initiated neutrophil response
US6427132B1 (en) * 1999-08-31 2002-07-30 Accenture Llp System, method and article of manufacture for demonstrating E-commerce capabilities via a simulation on a network
US6415270B1 (en) * 1999-09-03 2002-07-02 Omnihub, Inc. Multiple auction coordination method and system
AU3846801A (en) 2000-02-16 2001-08-27 Brigham & Womens Hospital Aspirin-triggered lipid mediators
EP1268393A2 (en) * 2000-03-20 2003-01-02 Trustees Of Boston University Lipoxin analogs and methods for the treatment of periodontal disease
ATE412448T1 (de) * 2001-03-02 2008-11-15 Brigham & Womens Hospital Lipoxin analoge als neue inhibitoren der angiogenese
US20040044028A1 (en) * 2001-03-30 2004-03-04 Obukowicz Mark G. Combinations of omega-3 fatty acids and cyclooxygenase-2 inhibitors for treatment or prevention of cardiovascular disease and treatment or prevention of cancer
WO2003039533A1 (en) * 2001-11-06 2003-05-15 The Brigham And Women's Hospital, Inc. Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases
EP1458373A1 (en) * 2001-12-18 2004-09-22 The Brigham and Women's Hospital Use of lipoxin analogs to promote cell defense against gram-negative infections
WO2003053423A2 (en) 2001-12-18 2003-07-03 The Brigham And Women's Hospital Inhibition or prevention of infection by bacteria with epa, dha or analogs
US7582785B2 (en) 2002-04-01 2009-09-01 University Of Southern California Trihydroxy polyunsaturated eicosanoid derivatives
ES2527753T3 (es) * 2002-04-01 2015-01-29 University Of Southern California Eicosanoides trihidroxi poliinsaturados
AU2003238240A1 (en) 2002-06-17 2003-12-31 Resolvyx Pharmaceuticals ANALOGUES OF LIPID MEDIATORS DERIVED FROM OMEGA-3 PUFAs AND METHODS OF USE
US7759395B2 (en) 2002-08-12 2010-07-20 The Brigham And Women's Hospital, Inc. Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
ES2700133T3 (es) * 2002-08-12 2019-02-14 Brigham & Womens Hospital Resolvinas: modelos biológicos para intervenciones terapéuticas
WO2004078143A2 (en) 2003-03-05 2004-09-16 The Brigham And Women's Hospital Inc. Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs
US20050075398A1 (en) * 2003-08-05 2005-04-07 Bazan Nicolas G. Neuroprotectin D1 protects against cellular apoptosis, stroke damage, alzheimer's disease and retinal diseases
WO2005105025A1 (en) * 2004-04-14 2005-11-10 Boston University Methods and compositions for preventing or treating periodontal diseases
US20060293288A1 (en) 2005-01-07 2006-12-28 Serhan Charles N Use of resolvins to treat gastrointestinal diseases

Also Published As

Publication number Publication date
US20100016432A1 (en) 2010-01-21
JP2005535712A (ja) 2005-11-24
JP2016166234A (ja) 2016-09-15
JP6559092B2 (ja) 2019-08-14
US20130217771A1 (en) 2013-08-22
JP2015025010A (ja) 2015-02-05
WO2004014835A9 (en) 2004-07-08
DK2216318T3 (en) 2018-12-10
EP2216318A3 (en) 2010-11-24
EP2216318A2 (en) 2010-08-11
SI2216318T1 (sl) 2019-01-31
JP2019112465A (ja) 2019-07-11
US7585856B2 (en) 2009-09-08
AU2003258194B2 (en) 2009-11-12
JP6097536B2 (ja) 2017-03-15
JP2010132675A (ja) 2010-06-17
JP4845378B2 (ja) 2011-12-28
CA2495260C (en) 2012-05-29
JP5410314B2 (ja) 2014-02-05
ES2700133T3 (es) 2019-02-14
AU2010200473A1 (en) 2010-02-25
CA2495260A1 (en) 2004-02-19
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WO2004014835A2 (en) 2004-02-19
WO2004014835A3 (en) 2004-04-15
EP3584235A2 (en) 2019-12-25
EP3584235A3 (en) 2020-04-22
ATE449057T1 (de) 2009-12-15
AU2003258194A1 (en) 2004-02-25
JP2019112464A (ja) 2019-07-11
EP1537067A2 (en) 2005-06-08
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US20040116408A1 (en) 2004-06-17
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