HU201955B - Process for producing new ribofuranuronic acid derivatives and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing new ribofuranuronic acid derivatives and pharmaceutical compositions comprising such compounds Download PDF

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Publication number
HU201955B
HU201955B HU881638A HU163888A HU201955B HU 201955 B HU201955 B HU 201955B HU 881638 A HU881638 A HU 881638A HU 163888 A HU163888 A HU 163888A HU 201955 B HU201955 B HU 201955B
Authority
HU
Hungary
Prior art keywords
alkyl
formula
compounds
deoxy
purinyl
Prior art date
Application number
HU881638A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT48902A (en
Inventor
Fulvio Gradient
Arnold Vogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HUT48902A publication Critical patent/HUT48902A/hu
Publication of HU201955B publication Critical patent/HU201955B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU881638A 1987-04-06 1988-04-05 Process for producing new ribofuranuronic acid derivatives and pharmaceutical compositions comprising such compounds HU201955B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3711561 1987-04-06
DE3711563 1987-04-06
DE3711564 1987-04-06
DE3711562 1987-04-06

Publications (2)

Publication Number Publication Date
HUT48902A HUT48902A (en) 1989-07-28
HU201955B true HU201955B (en) 1991-01-28

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
HU881638A HU201955B (en) 1987-04-06 1988-04-05 Process for producing new ribofuranuronic acid derivatives and pharmaceutical compositions comprising such compounds

Country Status (22)

Country Link
JP (1) JPS63258892A (fr)
KR (1) KR880012629A (fr)
AT (1) AT393507B (fr)
AU (1) AU609109B2 (fr)
BE (1) BE1002151A5 (fr)
CA (1) CA1326017C (fr)
CH (1) CH676121A5 (fr)
DK (1) DK183488A (fr)
ES (1) ES2007177A6 (fr)
FI (1) FI87463C (fr)
FR (1) FR2613367A1 (fr)
GB (1) GB2203149B (fr)
HU (1) HU201955B (fr)
IL (1) IL85969A (fr)
IT (1) IT1219892B (fr)
LU (1) LU87181A1 (fr)
MY (1) MY102323A (fr)
NL (1) NL8800862A (fr)
NZ (1) NZ224131A (fr)
PH (1) PH25424A (fr)
PT (1) PT87153B (fr)
SE (1) SE8801236A0 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
ID29609A (id) 1998-06-23 2001-09-06 Glaxo Group Ltd Turunan 2-(purin-9-il)-tetrahidrofuran-3,4-diol
WO2000063703A1 (fr) 1999-04-16 2000-10-26 Schering Corporation Utilisation de composes a base d'azetodinone
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
JP5011112B2 (ja) * 2004-09-20 2012-08-29 イノテック ファーマシューティカルズ コーポレイション プリン誘導体を含有する炎症性疾患の治療用医薬
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida

Also Published As

Publication number Publication date
PH25424A (fr) 1991-07-01
DK183488A (da) 1988-10-07
IT1219892B (it) 1990-05-24
SE8801236L (sv) 1988-10-17
GB8807750D0 (en) 1988-05-05
FI87463C (fi) 1993-01-11
FI881571A (fi) 1988-10-07
SE8801236D0 (sv) 1988-04-05
BE1002151A5 (fr) 1990-08-07
IT8847794A0 (it) 1988-03-30
ATA87388A (de) 1991-04-15
PT87153B (pt) 1992-07-31
IL85969A0 (en) 1988-09-30
PT87153A (pt) 1988-05-01
GB2203149B (en) 1991-02-13
FR2613367A1 (fr) 1988-10-07
AU609109B2 (en) 1991-04-26
CA1326017C (fr) 1994-01-11
AT393507B (de) 1991-11-11
CH676121A5 (fr) 1990-12-14
KR880012629A (ko) 1988-11-28
HUT48902A (en) 1989-07-28
IL85969A (en) 1992-03-29
SE8801236A0 (sv) 1988-10-17
DK183488D0 (da) 1988-04-05
FI881571A0 (fi) 1988-04-05
MY102323A (en) 1992-05-28
ES2007177A6 (es) 1989-06-01
LU87181A1 (fr) 1988-11-17
GB2203149A (en) 1988-10-12
FI87463B (fi) 1992-09-30
NZ224131A (en) 1991-12-23
AU1415188A (en) 1988-10-06
JPS63258892A (ja) 1988-10-26
NL8800862A (nl) 1988-11-01

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee