HRP20161684T1 - Pripravci koji sadrže lipazu, proteazu i amilazu, namijenjeni liječenju insuficijencije gušterače - Google Patents
Pripravci koji sadrže lipazu, proteazu i amilazu, namijenjeni liječenju insuficijencije gušterače Download PDFInfo
- Publication number
- HRP20161684T1 HRP20161684T1 HRP20161684TT HRP20161684T HRP20161684T1 HR P20161684 T1 HRP20161684 T1 HR P20161684T1 HR P20161684T T HRP20161684T T HR P20161684TT HR P20161684 T HRP20161684 T HR P20161684T HR P20161684 T1 HRP20161684 T1 HR P20161684T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation according
- amylase
- protease
- lipase
- mammal
- Prior art date
Links
- 102000004882 Lipase Human genes 0.000 title claims 6
- 239000004367 Lipase Substances 0.000 title claims 6
- 108090001060 Lipase Proteins 0.000 title claims 6
- 235000019421 lipase Nutrition 0.000 title claims 6
- 239000004382 Amylase Substances 0.000 title claims 5
- 102000013142 Amylases Human genes 0.000 title claims 5
- 108010065511 Amylases Proteins 0.000 title claims 5
- 108091005804 Peptidases Proteins 0.000 title claims 5
- 239000004365 Protease Substances 0.000 title claims 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title claims 5
- 235000019418 amylase Nutrition 0.000 title claims 5
- 235000019419 proteases Nutrition 0.000 title claims 5
- 239000000203 mixture Substances 0.000 title claims 3
- 208000035467 Pancreatic insufficiency Diseases 0.000 title claims 2
- 241000124008 Mammalia Species 0.000 claims 3
- 239000004971 Cross linker Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 241000981399 Aspergillus melleus Species 0.000 claims 1
- 240000006439 Aspergillus oryzae Species 0.000 claims 1
- 241000589513 Burkholderia cepacia Species 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 206010025476 Malabsorption Diseases 0.000 claims 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 claims 1
- VYLDEYYOISNGST-UHFFFAOYSA-N bissulfosuccinimidyl suberate Chemical group O=C1C(S(=O)(=O)O)CC(=O)N1OC(=O)CCCCCCC(=O)ON1C(=O)C(S(O)(=O)=O)CC1=O VYLDEYYOISNGST-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- -1 sachets Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Claims (8)
1. Pripravak, naznačen time što sadrži lipazu, proteazu i amilazu, gdje je omjer između lipaze, proteaze i amilaze u navedenom pripravku otprilike 1:1:0,15 USP jedinica, gdje je lipaza umrežena kristalizirana lipaza iz bakterije Burkholderia cepacia, proteaza je kristalizirana proteaza iz gljivice Aspergillus melleus, a amilaza je amorfna amilaza iz gljivice Aspergillus oryzae.
2. Pripravak u skladu s patentnim zahtjevom 1, naznačen time što kristali lipaze su umreženi multifunkcionalnim umreživačem.
3. Pripravak u skladu s patentnim zahtjevom 2, naznačen time što je multifunkcionalni umreživač bis(sulfosukcinimidil)-suberat.
4. Pripravak u skladu s bilo kojim od patentnih zahtjeva 1 do 3, naznačen time što dodatno sadrži farmaceutski prihvatljivu pomoćnu tvar.
5. Pripravak u skladu s bilo kojim od patentnih zahtjeva 1 do 4, naznačen time što se pripravak u oralnom doziranju bira iz skupine koju čine tablete, kapsule, guste suspenzije, vrećice, suspenzije i dražeje.
6. Pripravak u skladu s bilo kojim od patentnih zahtjeva 1 do 5, naznačen time što je namijenjen upotrebi u liječenju malapsorpcije kod sisavca.
7. Pripravak u skladu s bilo kojim od patentnih zahtjeva 1 do 5, naznačen time što je namijenjen upotrebi u liječenju insuficijencije gušterače kod sisavca.
8. Pripravak u skladu s patentnim zahtjevom 6 ili 7, naznačen time što sisavac boluje od cistične fibroze.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61876404P | 2004-10-14 | 2004-10-14 | |
EP10158639.4A EP2198880B1 (en) | 2004-10-14 | 2005-10-14 | Compositions containing lipase, protease and amylase for treating pancreatic insufficiency |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20161684T1 true HRP20161684T1 (hr) | 2017-02-24 |
Family
ID=35840531
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20161684TT HRP20161684T1 (hr) | 2004-10-14 | 2016-12-08 | Pripravci koji sadrže lipazu, proteazu i amilazu, namijenjeni liječenju insuficijencije gušterače |
Country Status (24)
Country | Link |
---|---|
US (1) | US7718169B2 (hr) |
EP (2) | EP2198880B1 (hr) |
JP (1) | JP4908420B2 (hr) |
KR (1) | KR101333664B1 (hr) |
CN (1) | CN101068565B (hr) |
AT (1) | ATE474592T1 (hr) |
AU (1) | AU2005295754B2 (hr) |
BR (1) | BRPI0516515B1 (hr) |
CA (1) | CA2584069C (hr) |
CY (2) | CY1110838T1 (hr) |
DE (1) | DE602005022471D1 (hr) |
DK (2) | DK2198880T3 (hr) |
ES (2) | ES2352086T3 (hr) |
HK (1) | HK1109068A1 (hr) |
HR (1) | HRP20161684T1 (hr) |
HU (1) | HUE031245T2 (hr) |
LT (1) | LT2198880T (hr) |
MX (1) | MX2007004534A (hr) |
PL (2) | PL1809320T3 (hr) |
PT (2) | PT1809320E (hr) |
RU (1) | RU2385736C2 (hr) |
SI (2) | SI1809320T1 (hr) |
UA (1) | UA91521C2 (hr) |
WO (1) | WO2006044529A1 (hr) |
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IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
PT1729797E (pt) | 2004-03-22 | 2008-12-17 | Solvay Pharm Gmbh | Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos |
WO2006002453A2 (en) * | 2004-07-07 | 2006-01-12 | Biodevelops Pharma Entwicklung Gmbh | Use of a deubiquitinating compound for enhancing the expression of membrane proteins on the cell surface |
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AU2006274835B2 (en) | 2005-07-29 | 2012-05-24 | Abbott Laboratories Gmbh | Processes for the manufacture of sterilized pancreatin powder |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
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2005
- 2005-10-14 CN CN2005800410804A patent/CN101068565B/zh not_active Expired - Fee Related
- 2005-10-14 PT PT05814918T patent/PT1809320E/pt unknown
- 2005-10-14 EP EP10158639.4A patent/EP2198880B1/en active Active
- 2005-10-14 DE DE602005022471T patent/DE602005022471D1/de active Active
- 2005-10-14 MX MX2007004534A patent/MX2007004534A/es active IP Right Grant
- 2005-10-14 LT LTEP10158639.4T patent/LT2198880T/lt unknown
- 2005-10-14 KR KR1020077010937A patent/KR101333664B1/ko not_active IP Right Cessation
- 2005-10-14 PT PT101586394T patent/PT2198880T/pt unknown
- 2005-10-14 AU AU2005295754A patent/AU2005295754B2/en not_active Ceased
- 2005-10-14 BR BRPI0516515-6A patent/BRPI0516515B1/pt not_active IP Right Cessation
- 2005-10-14 UA UAA200705128A patent/UA91521C2/ru unknown
- 2005-10-14 SI SI200531137T patent/SI1809320T1/sl unknown
- 2005-10-14 US US11/251,278 patent/US7718169B2/en not_active Expired - Fee Related
- 2005-10-14 DK DK10158639.4T patent/DK2198880T3/en active
- 2005-10-14 ES ES05814918T patent/ES2352086T3/es active Active
- 2005-10-14 AT AT05814918T patent/ATE474592T1/de active
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- 2005-10-14 WO PCT/US2005/036802 patent/WO2006044529A1/en active Application Filing
- 2005-10-14 JP JP2007536877A patent/JP4908420B2/ja not_active Expired - Fee Related
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- 2005-10-14 HU HUE10158639A patent/HUE031245T2/en unknown
- 2005-10-14 DK DK05814918.8T patent/DK1809320T3/da active
- 2005-10-14 EP EP05814918A patent/EP1809320B1/en active Active
- 2005-10-14 ES ES10158639.4T patent/ES2614157T3/es active Active
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2007
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2010
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