HK1247954A1 - 由人類多能幹細胞產生間充質幹細胞的方法以及通過所述方法產生的間充質幹細胞 - Google Patents

由人類多能幹細胞產生間充質幹細胞的方法以及通過所述方法產生的間充質幹細胞

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Publication number
HK1247954A1
HK1247954A1 HK18106166.5A HK18106166A HK1247954A1 HK 1247954 A1 HK1247954 A1 HK 1247954A1 HK 18106166 A HK18106166 A HK 18106166A HK 1247954 A1 HK1247954 A1 HK 1247954A1
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Hong Kong
Prior art keywords
stem cells
mesenchymal stem
same
human pluripotent
producing
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HK18106166.5A
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English (en)
Inventor
金孝洙
姜炫在
李銀珠
朴永培
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株式会社大熊制药
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Application filed by 株式会社大熊制药 filed Critical 株式会社大熊制药
Publication of HK1247954A1 publication Critical patent/HK1247954A1/zh

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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
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    • C12N2501/39—Steroid hormones
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
HK18106166.5A 2009-10-27 2018-05-11 由人類多能幹細胞產生間充質幹細胞的方法以及通過所述方法產生的間充質幹細胞 HK1247954A1 (zh)

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KR1020090102458A KR101135636B1 (ko) 2009-10-27 2009-10-27 인간 만능줄기세포로부터 중배엽 줄기세포를 생산하는 방법 및 이에 의해 생성된 중배엽 줄기세포

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HK1247954A1 true HK1247954A1 (zh) 2018-10-05

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US (1) US9388384B2 (zh)
EP (1) EP2495311B1 (zh)
JP (2) JP5757434B2 (zh)
KR (1) KR101135636B1 (zh)
CN (2) CN102686724A (zh)
ES (1) ES2729860T3 (zh)
HK (1) HK1247954A1 (zh)
MY (1) MY151979A (zh)
RU (1) RU2528250C2 (zh)
WO (1) WO2011052818A1 (zh)

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KR101669124B1 (ko) * 2013-07-11 2016-10-25 서울대학교병원 인간 배아줄기세포에서 유래된 중간엽 줄기세포를 유효성분으로 함유하는 간섬유화 또는 간경화 예방 및 치료용 조성물
KR101542850B1 (ko) * 2013-11-01 2015-08-10 주식회사 비비에이치씨 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 지방세포로 분화시키는 방법
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RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
WO2016180991A1 (es) * 2015-05-08 2016-11-17 Indiba, S.A. Procedimiento in vitro de proliferacion de celulas madre y uso de un dispositivo para incrementar la proliferacion de celulas madre in vitro
ES2828604T3 (es) 2015-06-26 2021-05-27 Donaldson Co Inc Medios compuestos para corrientes de combustible
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
KR101798217B1 (ko) * 2016-10-21 2017-11-15 차의과학대학교 산학협력단 만능줄기세포로부터 유래된 중간엽줄기세포를 선별하는 방법
KR101896803B1 (ko) * 2016-12-12 2018-09-07 서울대학교병원 인간 만능줄기세포로부터 중간엽 줄기세포로의 분화 유도 생산율을 증가시키는 방법 및 이에 의해 생성된 중간엽 줄기세포
CN106591228B (zh) * 2016-12-21 2019-06-18 中国科学院生物物理研究所 一种同时抵抗细胞衰老及恶性转化的人多能干细胞的制备方法
KR20180112547A (ko) * 2017-04-04 2018-10-12 경북대학교 산학협력단 역분화 줄기세포의 지속적인 계대배양을 통한 중간엽 줄기세포로의 분화방법
CN107375329A (zh) * 2017-06-12 2017-11-24 佛山科学技术学院 一种治疗犬关节炎的干细胞制剂及其制备方法
US11135250B2 (en) * 2017-10-25 2021-10-05 Cellatoz Therapeutics, Inc. Musculoskeletal stem cell
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CN108570448B (zh) * 2018-01-26 2019-04-02 皓昇莱生物制药有限公司 一种高效的hPSCs向MSCs分化的方法
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Publication number Publication date
CN102686724A (zh) 2012-09-19
EP2495311A4 (en) 2014-03-19
MY151979A (en) 2014-07-31
KR20110045760A (ko) 2011-05-04
JP2015107124A (ja) 2015-06-11
RU2528250C2 (ru) 2014-09-10
EP2495311A1 (en) 2012-09-05
WO2011052818A1 (ko) 2011-05-05
US20120276625A1 (en) 2012-11-01
KR101135636B1 (ko) 2012-04-17
JP5757434B2 (ja) 2015-07-29
ES2729860T3 (es) 2019-11-06
JP5947921B2 (ja) 2016-07-06
US9388384B2 (en) 2016-07-12
JP2013507981A (ja) 2013-03-07
RU2012121842A (ru) 2013-12-10
CN107574146A (zh) 2018-01-12
EP2495311B1 (en) 2019-03-13

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