HK1225303A1 - 使用貝那利珠單抗改善哮喘症狀的方法 - Google Patents

使用貝那利珠單抗改善哮喘症狀的方法

Info

Publication number
HK1225303A1
HK1225303A1 HK16113685A HK16113685A HK1225303A1 HK 1225303 A1 HK1225303 A1 HK 1225303A1 HK 16113685 A HK16113685 A HK 16113685A HK 16113685 A HK16113685 A HK 16113685A HK 1225303 A1 HK1225303 A1 HK 1225303A1
Authority
HK
Hong Kong
Prior art keywords
benralizumab
methods
asthma symptoms
improving asthma
improving
Prior art date
Application number
HK16113685A
Other languages
English (en)
Inventor
Christine Ward
Lorin Roskos
Bing Wang
Donald Raible
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of HK1225303A1 publication Critical patent/HK1225303A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK16113685A 2013-08-12 2016-12-01 使用貝那利珠單抗改善哮喘症狀的方法 HK1225303A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361864950P 2013-08-12 2013-08-12

Publications (1)

Publication Number Publication Date
HK1225303A1 true HK1225303A1 (zh) 2017-09-08

Family

ID=52448839

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16109789.8A HK1221647A1 (zh) 2013-08-12 2016-08-16 使用貝那利珠單抗改善哮喘症狀的方法
HK16113685A HK1225303A1 (zh) 2013-08-12 2016-12-01 使用貝那利珠單抗改善哮喘症狀的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16109789.8A HK1221647A1 (zh) 2013-08-12 2016-08-16 使用貝那利珠單抗改善哮喘症狀的方法

Country Status (18)

Country Link
US (1) US9441047B2 (zh)
EP (3) EP3536339B1 (zh)
JP (2) JP6803229B2 (zh)
KR (1) KR102337601B1 (zh)
CN (2) CN111617244A (zh)
AU (3) AU2014306960B2 (zh)
BR (1) BR112016002462A8 (zh)
CA (1) CA2918050C (zh)
DK (2) DK3536339T3 (zh)
ES (2) ES2740355T3 (zh)
HK (2) HK1221647A1 (zh)
HU (2) HUE057065T2 (zh)
MX (1) MX368474B (zh)
PL (2) PL3033103T3 (zh)
RU (2) RU2728578C2 (zh)
SG (1) SG11201600484TA (zh)
TR (1) TR201910413T4 (zh)
WO (1) WO2015023508A2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3033104T3 (pl) * 2013-08-12 2019-09-30 Astrazeneca Ab Sposoby zwiększania natężonej objętości wydechowej u astmatyków za pomocą benralizumabu
SG11201600481UA (en) 2013-08-12 2016-02-26 Medimmune Llc Methods for reducing exacerbation rates of asthma using benralizumab
RU2706729C2 (ru) * 2013-10-15 2019-11-20 Астразенека Аб Способы лечения хронической обструктивной болезни легких с использованием бенрализумаба
JP2018538249A (ja) 2015-11-04 2018-12-27 アストラゼネカ アクチボラグ 好酸球性疾患における好酸球標的化治療薬に対する臨床応答の予測変数としてのジペプチジルペプチダーゼ−4およびペリオスチン
US20180056018A1 (en) * 2016-08-31 2018-03-01 Cephalon, Inc. Inhalation Systems, Devices and Methods
TW202214692A (zh) * 2020-06-05 2022-04-16 瑞典商阿斯特捷利康公司 治療患有鼻瘜肉的患者的重度氣喘之方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6018032A (en) 1995-09-11 2000-01-25 Kyowa Hakko Kogyo Co., Ltd. Antibody against human interleukin-5-receptor α chain
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
ES2568898T3 (es) 1999-04-09 2016-05-05 Kyowa Hakko Kirin Co., Ltd. Procedimiento para controlar la actividad de una molécula inmunofuncional
AU2001232304A1 (en) 2000-02-15 2001-08-27 Kyowa Hakko Kogyo Co. Ltd. Eosinophil-specific apoptosis inducer
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
US7662925B2 (en) 2002-03-01 2010-02-16 Xencor, Inc. Optimized Fc variants and methods for their generation
WO2005035583A1 (ja) 2003-10-08 2005-04-21 Kyowa Hakko Kogyo Co., Ltd. Il-5受容体に特異的に結合する抗体組成物
US20060014680A1 (en) 2004-07-13 2006-01-19 Caiding Xu Peptides and compounds that bind to the IL-5 receptor
EP1931709B1 (en) 2005-10-03 2016-12-07 Xencor, Inc. Fc variants with optimized fc receptor binding properties
HUE036885T2 (hu) * 2007-05-14 2018-08-28 Astrazeneca Ab Eljárás a bazofil-szint csökkentésére
KR101615420B1 (ko) * 2010-12-16 2016-04-26 제넨테크, 인크. Th2 억제에 관한 진단 및 치료
US8961965B2 (en) * 2011-05-18 2015-02-24 Medimmune, Llc Methods of diagnosing and treating pulmonary diseases or disorders
CA2853858A1 (en) 2011-11-01 2013-05-10 Medimmune, Llc Methods for reducing the frequency and severity of acute exacerbations of asthma
PL3033104T3 (pl) * 2013-08-12 2019-09-30 Astrazeneca Ab Sposoby zwiększania natężonej objętości wydechowej u astmatyków za pomocą benralizumabu
SG11201600481UA (en) 2013-08-12 2016-02-26 Medimmune Llc Methods for reducing exacerbation rates of asthma using benralizumab

Also Published As

Publication number Publication date
WO2015023508A2 (en) 2015-02-19
CN105451761A (zh) 2016-03-30
US9441047B2 (en) 2016-09-13
PL3033103T3 (pl) 2019-10-31
PL3536339T3 (pl) 2022-02-21
HUE045402T2 (hu) 2019-12-30
CA2918050C (en) 2023-10-03
MX368474B (es) 2019-10-04
WO2015023508A8 (en) 2015-10-15
EP3536339B1 (en) 2021-10-06
RU2016108734A3 (zh) 2018-06-18
EP3536339A1 (en) 2019-09-11
HK1221647A1 (zh) 2017-06-09
RU2016108734A (ru) 2017-09-19
ES2901634T3 (es) 2022-03-23
TR201910413T4 (tr) 2019-08-21
RU2728578C2 (ru) 2020-07-30
AU2020202564A1 (en) 2020-05-07
BR112016002462A8 (pt) 2018-06-12
HUE057065T2 (hu) 2022-04-28
US20150044204A1 (en) 2015-02-12
EP3033103B1 (en) 2019-06-05
KR20160042123A (ko) 2016-04-18
MX2016001195A (es) 2016-07-21
KR102337601B1 (ko) 2021-12-10
JP2020100653A (ja) 2020-07-02
WO2015023508A3 (en) 2015-04-16
SG11201600484TA (en) 2016-02-26
EP3033103A4 (en) 2017-03-22
EP3988114A1 (en) 2022-04-27
DK3033103T3 (da) 2019-08-05
JP6803229B2 (ja) 2020-12-23
ES2740355T3 (es) 2020-02-05
EP3033103A2 (en) 2016-06-22
AU2014306960B2 (en) 2020-01-16
AU2023214323A1 (en) 2023-10-19
CN111617244A (zh) 2020-09-04
JP2016527326A (ja) 2016-09-08
CA2918050A1 (en) 2015-02-19
AU2014306960A1 (en) 2016-02-04
RU2020123894A (ru) 2020-09-18
DK3536339T3 (da) 2021-12-20
BR112016002462A2 (pt) 2017-09-12

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