HK1202802A1 - Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof - Google Patents
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereofInfo
- Publication number
- HK1202802A1 HK1202802A1 HK15103398.5A HK15103398A HK1202802A1 HK 1202802 A1 HK1202802 A1 HK 1202802A1 HK 15103398 A HK15103398 A HK 15103398A HK 1202802 A1 HK1202802 A1 HK 1202802A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- agent therapy
- companion diagnostic
- hyaluronan agent
- hyaluronan
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2474—Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
- G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161628187P | 2011-10-24 | 2011-10-24 | |
US201161559011P | 2011-11-11 | 2011-11-11 | |
US201161630765P | 2011-12-16 | 2011-12-16 | |
US201261714700P | 2012-10-16 | 2012-10-16 | |
PCT/US2012/061743 WO2013063155A2 (en) | 2011-10-24 | 2012-10-24 | Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1202802A1 true HK1202802A1 (en) | 2015-10-09 |
Family
ID=47116517
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK15103398.5A HK1202802A1 (en) | 2011-10-24 | 2015-04-07 | Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof |
HK16101363.9A HK1213206A1 (zh) | 2011-10-24 | 2016-02-04 | 用於抗透明質酸試劑療法的搭配診斷及其使用方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16101363.9A HK1213206A1 (zh) | 2011-10-24 | 2016-02-04 | 用於抗透明質酸試劑療法的搭配診斷及其使用方法 |
Country Status (14)
Country | Link |
---|---|
US (2) | US8846034B2 (pt) |
EP (2) | EP2915542A1 (pt) |
JP (1) | JP6162707B2 (pt) |
KR (1) | KR101828828B1 (pt) |
CN (1) | CN104093415B (pt) |
AU (1) | AU2012328880B2 (pt) |
BR (1) | BR112014009797A2 (pt) |
CA (1) | CA2853358A1 (pt) |
EA (1) | EA030440B1 (pt) |
HK (2) | HK1202802A1 (pt) |
IL (1) | IL232229B (pt) |
MX (1) | MX342735B (pt) |
SG (1) | SG11201401797TA (pt) |
WO (1) | WO2013063155A2 (pt) |
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CN103381267A (zh) | 2008-04-14 | 2013-11-06 | 哈洛齐梅公司 | 修饰的透明质酸酶及其在治疗透明质酸相关疾病和病症中的应用 |
TWI394580B (zh) | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
ES2724588T3 (es) | 2008-12-09 | 2019-09-12 | Halozyme Inc | Polipéptidos de PH20 soluble extendida y usos de los mismos |
CA2806058C (en) | 2010-07-20 | 2016-09-13 | Halozyme, Inc. | Adverse side-effects associated with administration of anti-hyaluronan agents and methods for ameliorating or preventing the side-effects |
US20130011378A1 (en) | 2011-06-17 | 2013-01-10 | Tzung-Horng Yang | Stable formulations of a hyaluronan-degrading enzyme |
CA2853358A1 (en) | 2011-10-24 | 2013-05-02 | Halozyme, Inc. | Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof |
DK2797622T3 (en) | 2011-12-30 | 2017-01-16 | Halozyme Inc | PH20 polypeptide variants, formulations and uses thereof |
RS57449B1 (sr) | 2012-04-04 | 2018-09-28 | Halozyme Inc | Kombinovana terapija sa hijaluronidazom i taksanom koji ciljno deluje na tumor |
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EP2935589A1 (en) * | 2012-12-18 | 2015-10-28 | Novartis AG | Compositions and methods that utilize a peptide tag that binds to hyaluronan |
WO2014111744A1 (en) | 2013-01-16 | 2014-07-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A soluble fibroblast growth factor receptor 3 (fgr3) polypeptide for use in the prevention or treatment of skeletal growth retardation disorders |
WO2015198243A2 (en) * | 2014-06-25 | 2015-12-30 | Novartis Ag | Compositions and methods for long acting proteins |
EP3160512B1 (en) * | 2014-06-25 | 2019-05-22 | Novartis AG | Compositions and methods for visualization of the vitreous |
EP3160991A2 (en) * | 2014-06-25 | 2017-05-03 | Novartis AG | Compositions and methods for long acting proteins |
EP3166623B1 (en) | 2014-07-10 | 2020-05-13 | Academia Sinica | Multi-drug delivery system and uses thereof |
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JP6959912B2 (ja) | 2015-09-23 | 2021-11-05 | ジェネンテック, インコーポレイテッド | 抗vegf抗体の最適化変異体 |
WO2017059269A1 (en) | 2015-10-02 | 2017-04-06 | Southern Research Institute | Imaging phantom and systems and methods of using same |
KR101698003B1 (ko) * | 2016-06-20 | 2017-01-19 | 여오영 | 퀴닌 염 현탁액을 포함하는 항암 치료를 위한 국소 투여용 주사제 조성물 |
MX2018016257A (es) | 2016-07-07 | 2019-11-21 | Therachon Sas | Polipéptidos del receptor 3 del factor de crecimiento de fibroblastos solubles (sfgfr3) y usos de los mismos. |
EP3516397A1 (en) * | 2016-09-23 | 2019-07-31 | Ventana Medical Systems, Inc. | Methods and systems for scoring extracellular matrix biomarkers in tumor samples |
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US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
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CN110004105B (zh) * | 2018-01-05 | 2023-09-29 | 上海普佑生物医药有限公司 | 一种蛋白在细胞培养中的应用 |
MX2021013349A (es) * | 2019-04-30 | 2022-02-03 | Haplnscience Inc | Composicion para la prevencion o el tratamiento de la caida del cabello que incluye hapln1. |
WO2020227364A1 (en) * | 2019-05-07 | 2020-11-12 | Genzyme Corporation | Methods for quantifying drug concentration in a prodrug composition |
JP2022553640A (ja) | 2019-10-10 | 2022-12-26 | コディアック サイエンシーズ インコーポレイテッド | 眼障害を処置する方法 |
KR102166453B1 (ko) * | 2020-02-03 | 2020-10-15 | 중앙대학교 산학협력단 | Hapln1을 포함하는 폐질환 예방 또는 치료용 조성물 |
CN111218452B (zh) * | 2020-02-25 | 2022-11-15 | 芜湖天明生物技术有限公司 | 一种重组人tsg-6基因、重组人tsg-6蛋白标准品及其制备方法和应用 |
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CN111449684B (zh) * | 2020-04-09 | 2023-05-05 | 济南康硕生物技术有限公司 | 心脏超声标准扫查切面快速获取方法及*** |
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-
2012
- 2012-10-24 CA CA2853358A patent/CA2853358A1/en not_active Abandoned
- 2012-10-24 MX MX2014004870A patent/MX342735B/es active IP Right Grant
- 2012-10-24 EP EP15163402.9A patent/EP2915542A1/en not_active Withdrawn
- 2012-10-24 EP EP12780623.0A patent/EP2771028A2/en not_active Withdrawn
- 2012-10-24 SG SG11201401797TA patent/SG11201401797TA/en unknown
- 2012-10-24 JP JP2014538961A patent/JP6162707B2/ja not_active Expired - Fee Related
- 2012-10-24 US US13/694,071 patent/US8846034B2/en not_active Expired - Fee Related
- 2012-10-24 CN CN201280064239.4A patent/CN104093415B/zh not_active Expired - Fee Related
- 2012-10-24 BR BR112014009797-6A patent/BR112014009797A2/pt not_active Application Discontinuation
- 2012-10-24 KR KR1020147013966A patent/KR101828828B1/ko active IP Right Grant
- 2012-10-24 WO PCT/US2012/061743 patent/WO2013063155A2/en active Application Filing
- 2012-10-24 AU AU2012328880A patent/AU2012328880B2/en not_active Ceased
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- 2014-08-14 US US14/459,876 patent/US9458442B2/en not_active Expired - Fee Related
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- 2015-04-07 HK HK15103398.5A patent/HK1202802A1/xx not_active IP Right Cessation
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MX2014004870A (es) | 2014-10-14 |
IL232229A0 (en) | 2014-06-30 |
WO2013063155A3 (en) | 2013-07-11 |
US8846034B2 (en) | 2014-09-30 |
US9458442B2 (en) | 2016-10-04 |
EP2771028A2 (en) | 2014-09-03 |
AU2012328880B2 (en) | 2017-02-23 |
EA201400491A1 (ru) | 2015-08-31 |
US20130202583A1 (en) | 2013-08-08 |
JP2014532865A (ja) | 2014-12-08 |
KR20140092851A (ko) | 2014-07-24 |
SG11201401797TA (en) | 2014-09-26 |
IL232229B (en) | 2019-05-30 |
EA030440B1 (ru) | 2018-08-31 |
WO2013063155A2 (en) | 2013-05-02 |
HK1213206A1 (zh) | 2016-06-30 |
EP2915542A1 (en) | 2015-09-09 |
KR101828828B1 (ko) | 2018-03-29 |
US20150218544A9 (en) | 2015-08-06 |
JP6162707B2 (ja) | 2017-07-12 |
MX342735B (es) | 2016-10-07 |
CA2853358A1 (en) | 2013-05-02 |
US20140348817A1 (en) | 2014-11-27 |
NZ624489A (en) | 2016-02-26 |
CN104093415A (zh) | 2014-10-08 |
BR112014009797A2 (pt) | 2020-10-27 |
CN104093415B (zh) | 2017-04-05 |
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