HK1096956A1 - Cysteine protease inhibitors - Google Patents

Cysteine protease inhibitors

Info

Publication number
HK1096956A1
HK1096956A1 HK07101596.9A HK07101596A HK1096956A1 HK 1096956 A1 HK1096956 A1 HK 1096956A1 HK 07101596 A HK07101596 A HK 07101596A HK 1096956 A1 HK1096956 A1 HK 1096956A1
Authority
HK
Hong Kong
Prior art keywords
protease inhibitors
cysteine protease
cysteine
inhibitors
protease
Prior art date
Application number
HK07101596.9A
Other languages
English (en)
Inventor
M Nilsson
X Zhou
L Oden
B Classon
R Noren
U Grabowska
P Jackson
P Fallon
A Carr
M Liley
M Tozer
T Johnson
V Diaz
L Crespo
J Kangasmetsa
T Bonnaud
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0400022A external-priority patent/SE0400022D0/xx
Priority claimed from SE0401332A external-priority patent/SE0401332D0/xx
Application filed by Medivir Ab filed Critical Medivir Ab
Publication of HK1096956A1 publication Critical patent/HK1096956A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK07101596.9A 2004-01-08 2007-02-09 Cysteine protease inhibitors HK1096956A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0400022A SE0400022D0 (sv) 2004-01-08 2004-01-08 New compounds
SE0401332A SE0401332D0 (sv) 2004-05-26 2004-05-26 New compounds
PCT/GB2005/050003 WO2005066180A1 (en) 2004-01-08 2005-01-06 Cysteine protease inhibitors

Publications (1)

Publication Number Publication Date
HK1096956A1 true HK1096956A1 (en) 2007-06-15

Family

ID=34752290

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07101596.9A HK1096956A1 (en) 2004-01-08 2007-02-09 Cysteine protease inhibitors

Country Status (13)

Country Link
US (2) US7915300B2 (ja)
EP (1) EP1701960B1 (ja)
JP (1) JP4787765B2 (ja)
AR (1) AR047373A1 (ja)
AT (1) ATE461200T1 (ja)
AU (1) AU2005203972B2 (ja)
BR (1) BRPI0506719A (ja)
CA (1) CA2552739A1 (ja)
DE (1) DE602005019971D1 (ja)
ES (1) ES2341869T3 (ja)
HK (1) HK1096956A1 (ja)
TW (1) TWI343384B (ja)
WO (1) WO2005066180A1 (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2341869T3 (es) 2004-01-08 2010-06-29 Medivir Aktiebolag Inhibidores de cisteina proteasa.
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
BRPI0511834A (pt) 2004-07-14 2008-01-08 Ptc Therapeutics Inc métodos por tratar hepatite c
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
WO2006019832A1 (en) 2004-07-22 2006-02-23 Ptc Therapeutics, Inc. Thienopyridines for treating hepatitis c
GB0513840D0 (en) * 2005-07-07 2005-08-10 Medivir Ab Cysteine protease inhibitors
GB0517279D0 (en) * 2005-08-23 2005-10-05 Amura Therapeutics Ltd Biologically active compounds
CN101282936B (zh) * 2005-10-07 2012-05-16 橘生药品工业株式会社 氮化杂环化合物及包含其的药物组合物
GB0611654D0 (en) * 2006-06-13 2006-07-19 Medivir Ab Compounds
GB0614053D0 (en) * 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614073D0 (en) * 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614042D0 (en) 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614037D0 (en) 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614052D0 (en) 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614046D0 (en) * 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0614044D0 (en) * 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds
GB0618263D0 (en) * 2006-09-18 2006-10-25 Medivir Ab Compound
WO2008114054A1 (en) * 2007-03-19 2008-09-25 Medivir Ab Protease inhibitors
KR20100023948A (ko) 2007-06-08 2010-03-04 닛뽕 케미파 가부시키가이샤 뇌동맥류의 치료 또는 예방약
US7893067B2 (en) 2007-06-27 2011-02-22 Medivir Ab Cysteine protease inhibitors
ES2656100T3 (es) 2007-08-13 2018-02-23 Monsanto Technology Llc Composiciones y procedimientos de control de nemátodos
WO2009054454A1 (ja) 2007-10-24 2009-04-30 National University Corporation Tokyo Medical And Dental University カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
EP2240491B1 (en) 2008-01-09 2015-07-15 Amura Therapeutics Limited TETRAHYDROFURO(2,3-b)PYRROL-3-ONE DERIVATIVES AS INHIBITORS OF CYSTEINE PROTEINASES
GB0804701D0 (en) 2008-03-13 2008-04-16 Amura Therapeutics Ltd Compounds
GB0817424D0 (en) 2008-09-24 2008-10-29 Medivir Ab Protease inhibitors
GB0916608D0 (en) 2009-09-22 2009-11-04 Angeletti P Ist Richerche Bio Therapeutic compounds
US10087190B1 (en) * 2017-04-24 2018-10-02 Purdue Research Foundation Lactones
US10995803B2 (en) 2018-12-04 2021-05-04 Means Industries, Inc. Electromagnetic system for controlling the operating mode of a non friction coupling assembly and coupling and magnetic control assembly having same
WO2022147694A1 (en) * 2021-01-06 2022-07-14 Beijing Erai Therapeutics Co., Ltd. Aminoheteroaryl compounds and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR013079A1 (es) * 1997-05-06 2000-12-13 Smithkline Beecham Corp Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios
GB0003111D0 (en) 2000-02-10 2000-03-29 Novartis Ag Organic compounds
DE60118793T2 (de) * 2000-11-17 2007-04-26 Medivir Ab Cystein protease inhibitoren
DK1362052T3 (da) 2001-01-17 2007-07-09 Amura Therapeutics Ltd Inhibitorer af cruzipain og andre cysteinproteaser
JP2003183161A (ja) * 2001-12-21 2003-07-03 Kitasato Inst:The 骨粗鬆症の予防治療剤
CN100548986C (zh) 2003-12-12 2009-10-14 默克弗罗斯特加拿大有限公司 组织蛋白酶半胱氨酸蛋白酶抑制剂
US20080200975A1 (en) 2004-01-06 2008-08-21 Nicast Ltd. Vascular Prosthesis with Anastomotic Member
CN1910175A (zh) 2004-01-08 2007-02-07 默克弗罗斯特加拿大有限公司 组织蛋白酶半胱氨酸蛋白酶抑制剂
ES2341869T3 (es) 2004-01-08 2010-06-29 Medivir Aktiebolag Inhibidores de cisteina proteasa.
GB0513839D0 (en) 2005-07-07 2005-08-10 Medivir Ab Cysteine protease inhibitors
GB0614052D0 (en) 2006-07-14 2006-08-23 Amura Therapeutics Ltd Compounds

Also Published As

Publication number Publication date
JP2007517852A (ja) 2007-07-05
US20080234260A1 (en) 2008-09-25
ES2341869T3 (es) 2010-06-29
EP1701960A1 (en) 2006-09-20
TWI343384B (en) 2011-06-11
CA2552739A1 (en) 2005-07-21
BRPI0506719A (pt) 2007-05-02
TW200536847A (en) 2005-11-16
EP1701960B1 (en) 2010-03-17
DE602005019971D1 (de) 2010-04-29
ATE461200T1 (de) 2010-04-15
WO2005066180A9 (en) 2008-09-25
AU2005203972B2 (en) 2010-11-18
AR047373A1 (es) 2006-01-18
JP4787765B2 (ja) 2011-10-05
AU2005203972A1 (en) 2005-07-21
WO2005066180A1 (en) 2005-07-21
US7915300B2 (en) 2011-03-29
US20110112089A1 (en) 2011-05-12

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140106