HK1078864A1 - Process for preparing optically pure active compounds - Google Patents

Process for preparing optically pure active compounds

Info

Publication number
HK1078864A1
HK1078864A1 HK05110824.6A HK05110824A HK1078864A1 HK 1078864 A1 HK1078864 A1 HK 1078864A1 HK 05110824 A HK05110824 A HK 05110824A HK 1078864 A1 HK1078864 A1 HK 1078864A1
Authority
HK
Hong Kong
Prior art keywords
active compounds
optically pure
pure active
preparing optically
preparing
Prior art date
Application number
HK05110824.6A
Other languages
English (en)
Inventor
Bernhard Kohl
Bernd Mueller
Ralf Steffen Weingart
Original Assignee
Takeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Gmbh filed Critical Takeda Gmbh
Publication of HK1078864A1 publication Critical patent/HK1078864A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Catalysts (AREA)
HK05110824.6A 2002-12-06 2005-11-28 Process for preparing optically pure active compounds HK1078864A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02027273 2002-12-06
DE10340255 2003-08-29
PCT/EP2003/013605 WO2004052882A1 (fr) 2002-12-06 2003-12-03 Procede de preparation de composes actifs optiquement pures

Publications (1)

Publication Number Publication Date
HK1078864A1 true HK1078864A1 (en) 2006-03-24

Family

ID=32509784

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05110824.6A HK1078864A1 (en) 2002-12-06 2005-11-28 Process for preparing optically pure active compounds

Country Status (28)

Country Link
US (1) US7452998B2 (fr)
EP (1) EP1578742B1 (fr)
JP (1) JP4612542B2 (fr)
KR (1) KR101062806B1 (fr)
CN (1) CN100482658C (fr)
AR (1) AR042277A1 (fr)
AU (1) AU2003289948B2 (fr)
BR (2) BRPI0310118B1 (fr)
CA (1) CA2507807C (fr)
CY (1) CY1114058T1 (fr)
DK (1) DK1578742T3 (fr)
EA (1) EA011771B1 (fr)
ES (1) ES2397380T3 (fr)
HK (1) HK1078864A1 (fr)
HR (1) HRP20050604B1 (fr)
IL (1) IL168456A (fr)
IS (1) IS2885B (fr)
ME (1) ME00563A (fr)
MX (1) MXPA05005762A (fr)
NO (1) NO330978B1 (fr)
NZ (1) NZ540815A (fr)
PL (1) PL375818A1 (fr)
PT (1) PT1578742E (fr)
RS (1) RS52667B (fr)
SI (1) SI1578742T1 (fr)
TW (1) TWI313268B (fr)
WO (1) WO2004052882A1 (fr)
ZA (1) ZA200503543B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1158985B1 (fr) 1999-01-13 2011-12-28 Bayer HealthCare LLC DIPHENYLE UREES A SUBSTITUTION OMEGA-CARBOXY ARYLE EN TANT QU'INHIBITEURS DE LA KINASE p38
AU2003293749B2 (en) * 2002-12-06 2009-12-24 Takeda Gmbh Process for preparing (S)-pantoprazole
FR2848555B1 (fr) * 2002-12-16 2006-07-28 Negma Gild Enantiomere(-)du tenatoprazole et son application en therapeutique
EP1572680A2 (fr) * 2002-12-19 2005-09-14 Eva Pharmaceutical Industries Ltd. États solides de sodium de pantoprazole et leurs procédés de préparation hydrates de sodium de pantoprazole connus
EP1615913A2 (fr) * 2003-06-10 2006-01-18 Teva Pharmaceutical Industries Limited Procede de preparation de benzimidazoles 2- (pyridinyl)methyl]sulfinyle substitues et nouveau derives chlorures de pantoprazole
US20070225500A1 (en) * 2004-06-02 2007-09-27 Altana Pharma Ag Process for the Preparation of Pyridin-2-Ylmethylsulphinyl-1H-Benzimidazol Compounds
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
KR20130038949A (ko) * 2004-06-24 2013-04-18 아스트라제네카 아베 에소메프라졸 나트륨염의 제조에서 사용하기 위한 결정 변형의 제조를 위한 신규한 방법
EP1801110A1 (fr) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Sel d'arginine d'ésoméprazole
US7579476B2 (en) * 2006-02-24 2009-08-25 Praktikatalyst Pharma, Llc Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals
EP2054403A1 (fr) * 2006-08-08 2009-05-06 Jubilant Organosys Limited Procédé de production de composés de sulfoxyde
JP5492417B2 (ja) 2006-10-13 2014-05-14 エーザイ・アール・アンド・ディー・マネジメント株式会社 胃酸分泌抑制作用を有するベンズイミダゾール化合物
EP2486910A3 (fr) 2006-10-27 2012-08-22 The Curators Of The University Of Missouri Appareil comprenant plusieurs chambres et une tête de distribution
US20110028518A1 (en) * 2008-03-18 2011-02-03 Dr. Reddy's Laboratories Ltd. Dexlansoprazole process and polymorphs
EP2143722A1 (fr) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Procédé de préparation de sodium ésoméprazole de haute pureté chimique et nouvelles formes de sodium ésoméprazole
EP2264024A1 (fr) 2008-10-14 2010-12-22 LEK Pharmaceuticals d.d. Procédé de préparation d'inhibiteurs de la pompe à protons énantiomériquement enrichis
US8071781B2 (en) 2008-11-11 2011-12-06 Syn-Tech Chem. & Pharm. Co., Ltd. Process for preparing rabeprazole sodium
KR20120114356A (ko) 2010-02-12 2012-10-16 에스티브 퀴미카 에스.에이. 에스오메프라졸 나트륨염의 제조공정
CN103113351B (zh) * 2013-03-08 2015-01-21 苏州特瑞药业有限公司 一种光学纯手性亚砜类化合物的制备方法
CN103936714A (zh) * 2014-04-15 2014-07-23 北京华禧联合科技发展有限公司 一种埃索美拉唑镁的制备方法
US10307748B2 (en) 2014-12-26 2019-06-04 The University Of Tokyo Method for producing proton pump inhibitor compound having optical activity
CN105440018A (zh) * 2015-11-27 2016-03-30 福州闽海药业有限公司 一种锆催化的右旋兰索拉唑的不对称氧化合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
SE465514B (sv) 1990-02-19 1991-09-23 Curt Pettersson Foerfarande och anvaendning av ett separationsmedium vid separation av enantiomerer
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
JPH08509736A (ja) 1993-04-27 1996-10-15 セプラコー，インコーポレイテッド 光学的に純粋な（−）パントプラゾールを用いる胃の疾患治療の方法と組成
CA2161130A1 (fr) 1993-04-27 1994-11-10 Nancy M. Gray Methodes et compositions pour le traitement de troubles gastriques grace a du (+) pantoprazole optiquement pur
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423970D0 (en) 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) 1994-11-28 1995-01-11 Astra Ab Resolution
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
AU2003293749B2 (en) * 2002-12-06 2009-12-24 Takeda Gmbh Process for preparing (S)-pantoprazole

Also Published As

Publication number Publication date
RS52667B (en) 2013-06-28
EP1578742A1 (fr) 2005-09-28
US7452998B2 (en) 2008-11-18
CN1717403A (zh) 2006-01-04
ES2397380T3 (es) 2013-03-06
KR101062806B1 (ko) 2011-09-07
AR042277A1 (es) 2005-06-15
TW200508219A (en) 2005-03-01
PT1578742E (pt) 2013-01-24
IS2885B (is) 2014-07-15
AU2003289948A1 (en) 2004-06-30
NO20053099L (no) 2005-06-24
CN100482658C (zh) 2009-04-29
EA200500898A1 (ru) 2005-12-29
JP4612542B2 (ja) 2011-01-12
NO20053099D0 (no) 2005-06-24
HRP20050604B1 (hr) 2013-09-30
CA2507807A1 (fr) 2004-06-24
CY1114058T1 (el) 2016-07-27
NZ540815A (en) 2008-03-28
DK1578742T3 (da) 2013-01-21
CA2507807C (fr) 2013-10-22
MXPA05005762A (es) 2005-08-16
US20050288334A1 (en) 2005-12-29
JP2006516261A (ja) 2006-06-29
ZA200503543B (en) 2006-08-30
WO2004052882A1 (fr) 2004-06-24
EA011771B1 (ru) 2009-06-30
SI1578742T1 (sl) 2013-02-28
NO330978B1 (no) 2011-08-29
BRPI0310118B1 (pt) 2015-10-20
RS20050423A (en) 2007-04-10
IS7909A (is) 2005-06-23
BR0317005A (pt) 2005-10-25
PL375818A1 (en) 2005-12-12
AU2003289948B2 (en) 2009-12-24
KR20050085224A (ko) 2005-08-29
HRP20050604A2 (en) 2006-09-30
IL168456A (en) 2012-02-29
EP1578742B1 (fr) 2012-10-17
ME00563A (en) 2011-12-20
TWI313268B (en) 2009-08-11

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20161203