HK1071570A1 - Pyrazolopyrimidines as cyclin dependent kinase inhibitors - Google Patents

Pyrazolopyrimidines as cyclin dependent kinase inhibitors

Info

Publication number
HK1071570A1
HK1071570A1 HK05104671A HK05104671A HK1071570A1 HK 1071570 A1 HK1071570 A1 HK 1071570A1 HK 05104671 A HK05104671 A HK 05104671A HK 05104671 A HK05104671 A HK 05104671A HK 1071570 A1 HK1071570 A1 HK 1071570A1
Authority
HK
Hong Kong
Prior art keywords
pyrazolopyrimidines
kinase inhibitors
dependent kinase
cyclin dependent
cyclin
Prior art date
Application number
HK05104671A
Other languages
English (en)
Inventor
Timothy J Guzi
Kamil Paruch
Ronald J Doll
Michael P Dwyer
Lawrence W Dillard
Vinh D Tran
Zhen Min He
Ray Anthony James
Park Haengsoon
Viyyoor Moopil Girijavallabhan
Original Assignee
Schering Corp
Pharmacopeia Drug Discovery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Pharmacopeia Drug Discovery filed Critical Schering Corp
Publication of HK1071570A1 publication Critical patent/HK1071570A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
HK05104671A 2002-09-04 2005-06-02 Pyrazolopyrimidines as cyclin dependent kinase inhibitors HK1071570A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40803002P 2002-09-04 2002-09-04
PCT/US2003/027405 WO2004022559A1 (en) 2002-09-04 2003-09-03 Pyrazolopyrimidines as cyclin dependent kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1071570A1 true HK1071570A1 (en) 2005-07-22

Family

ID=31978549

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05104671A HK1071570A1 (en) 2002-09-04 2005-06-02 Pyrazolopyrimidines as cyclin dependent kinase inhibitors

Country Status (18)

Country Link
US (2) US7078525B2 (xx)
EP (1) EP1534709B1 (xx)
JP (2) JP2006501260A (xx)
KR (1) KR20050058507A (xx)
CN (1) CN1310918C (xx)
AR (1) AR041134A1 (xx)
AT (1) ATE364608T1 (xx)
CA (1) CA2497444C (xx)
DE (1) DE60314427T2 (xx)
ES (1) ES2285164T3 (xx)
HK (1) HK1071570A1 (xx)
MX (1) MXPA05002573A (xx)
MY (1) MY139336A (xx)
NZ (1) NZ539162A (xx)
PE (1) PE20041076A1 (xx)
TW (1) TW200413377A (xx)
WO (1) WO2004022559A1 (xx)
ZA (1) ZA200501851B (xx)

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Also Published As

Publication number Publication date
CN1738821A (zh) 2006-02-22
DE60314427T2 (de) 2008-06-12
CN1310918C (zh) 2007-04-18
KR20050058507A (ko) 2005-06-16
AU2003268357A1 (en) 2004-03-29
WO2004022559A1 (en) 2004-03-18
EP1534709B1 (en) 2007-06-13
AR041134A1 (es) 2005-05-04
EP1534709A1 (en) 2005-06-01
DE60314427D1 (de) 2007-07-26
CA2497444A1 (en) 2004-03-18
US7470695B2 (en) 2008-12-30
ATE364608T1 (de) 2007-07-15
MY139336A (en) 2009-09-30
US7078525B2 (en) 2006-07-18
NZ539162A (en) 2006-07-28
ZA200501851B (en) 2005-09-08
TW200413377A (en) 2004-08-01
US20060235025A1 (en) 2006-10-19
JP2006501260A (ja) 2006-01-12
JP2010132704A (ja) 2010-06-17
PE20041076A1 (es) 2005-01-22
ES2285164T3 (es) 2007-11-16
CA2497444C (en) 2010-11-30
US20040102451A1 (en) 2004-05-27
MXPA05002573A (es) 2005-09-08

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Legal Events

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CORR Corrigendum

Free format text: CORRECTED DATA OF SECTION 20 TO JOURNAL OF 20050722: [54] PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS

PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110903