HK1061661A1 - Use of flumazenil in developing a drug for the treatment of alcohol dependence - Google Patents

Use of flumazenil in developing a drug for the treatment of alcohol dependence

Info

Publication number
HK1061661A1
HK1061661A1 HK04104732A HK04104732A HK1061661A1 HK 1061661 A1 HK1061661 A1 HK 1061661A1 HK 04104732 A HK04104732 A HK 04104732A HK 04104732 A HK04104732 A HK 04104732A HK 1061661 A1 HK1061661 A1 HK 1061661A1
Authority
HK
Hong Kong
Prior art keywords
flumazenil
developing
drug
alcohol dependence
treatment
Prior art date
Application number
HK04104732A
Other languages
English (en)
Inventor
Juan Jose Legarda Ibanez
Original Assignee
Hythiam Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hythiam Inc filed Critical Hythiam Inc
Publication of HK1061661A1 publication Critical patent/HK1061661A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Addiction (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
HK04104732A 2001-01-17 2004-07-02 Use of flumazenil in developing a drug for the treatment of alcohol dependence HK1061661A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200100106 2001-01-17
PCT/ES2002/000008 WO2002056964A1 (es) 2001-01-17 2002-01-10 Empleo de flumazenilo en la elaboración de una medicación para el tratamiento de la dependencia de alcohol

Publications (1)

Publication Number Publication Date
HK1061661A1 true HK1061661A1 (en) 2004-09-30

Family

ID=8496426

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04104732A HK1061661A1 (en) 2001-01-17 2004-07-02 Use of flumazenil in developing a drug for the treatment of alcohol dependence

Country Status (23)

Country Link
US (2) US7348321B2 (pt)
EP (1) EP1374952B1 (pt)
JP (2) JP2004519461A (pt)
KR (1) KR100712570B1 (pt)
CN (1) CN1486205A (pt)
AT (1) ATE338575T1 (pt)
AU (1) AU2002226427B2 (pt)
BR (1) BR0206549A (pt)
CA (1) CA2433833C (pt)
CR (1) CR7049A (pt)
CY (1) CY1107500T1 (pt)
DE (1) DE60214527T2 (pt)
DK (1) DK1374952T3 (pt)
ES (1) ES2269661T3 (pt)
HK (1) HK1061661A1 (pt)
IL (1) IL156798A0 (pt)
MX (1) MXPA03006411A (pt)
NZ (2) NZ527583A (pt)
PT (1) PT1374952E (pt)
RU (1) RU2300378C2 (pt)
UA (1) UA78199C2 (pt)
WO (1) WO2002056964A1 (pt)
ZA (1) ZA200305922B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192271A1 (en) 2003-07-15 2005-09-01 Hythiam, Inc. Use of selective chloride channel modulators to treat alcohol and/or stimulant substance abuse
US20060172998A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
US20060172996A1 (en) * 2005-02-03 2006-08-03 Halikas James A Method of preventing relapse in the abstinent substance dependent individual
EP1868593A2 (en) * 2005-04-07 2007-12-26 Hythiam, Inc. Improved methods of and compositions for the prevention of anxiety, substance abuse, and dependence
US20060263304A1 (en) * 2005-05-23 2006-11-23 Halikas James A Method of controlling alcohol intake and reversing alcohol effects
SG183696A1 (en) * 2007-08-06 2012-09-27 Biotie Therapies Inc Medicaments comprising nepicastat for use in treating dependence on a substance
EP2186517A4 (en) * 2007-08-08 2010-08-18 Ibanez Juan Jose Legarda USE AND METHODS OF USING A SEROTONIN3 (5-HT3) RECEPTOR ANTAGONIST AND CHLORIDE CHANNEL MODULATOR FOR THE TREATMENT OF DRUG OR DRUG ADDICTION OR DEPENDENCE OR CENTER NERVOUS DISORDERS
AU2010215075B2 (en) * 2009-02-20 2015-08-20 Palmaya Pty Ltd Pharmaceutical preparation and delivery system
US8930050B2 (en) * 2009-04-29 2015-01-06 Marine Canada Acquisition Inc. Method and system for increasing or decreasing engine throttle in a marine vessel
US20100280684A1 (en) * 2009-04-29 2010-11-04 Pierre Garon Synchronization of shift and throttle controls in a marine vessel
US8347859B2 (en) * 2009-04-29 2013-01-08 Marine Canada Acquisition Inc. Automatic throttle calibration in a marine vessel
US8387589B2 (en) * 2009-04-29 2013-03-05 Marine Canada Acqusition Inc. Position sensor for an output shaft used in a shift and throttle system
US8406944B2 (en) * 2010-02-10 2013-03-26 Pierre Garon Control system and method for starting and stopping marine engines
US8845490B2 (en) 2010-02-10 2014-09-30 Marine Canada Acquisition Inc. Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
US8182396B2 (en) * 2010-02-10 2012-05-22 Marine Canada Acquisition In.c Method and system for delaying shift and throttle commands based on engine speed in a marine vessel
AU2012221704B2 (en) 2011-02-23 2013-12-05 Coeruleus Ltd. Flumazenil complexes, compositions comprising same and uses thereof
RU2468799C1 (ru) * 2011-08-03 2012-12-10 Общество с ограниченной ответственностью "Урал Крафт" Способ купирования алкогольного абстинентного синдрома посредством блокады бензодиазепиновых рецепторов

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519017A (en) * 1990-03-29 1996-05-21 Lts Lohmann Therapie-Systeme Gmbh + Co. Kg Pharmaceutic formulation for the treatment of alcoholism
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
GB9420010D0 (en) 1994-10-01 1994-11-16 Marck Sharp & Dohme Limited Nucleic acids
US20030176456A1 (en) * 2001-12-21 2003-09-18 June Harry L. Methods for reducing alcohol cravings in chronic alcoholics
US6740677B2 (en) 2002-08-19 2004-05-25 Hong Xue Methods of treating benzodiazepine site (BZD-S) associated syndromes using 2′ hydroxyflavonoids

Also Published As

Publication number Publication date
NZ539400A (en) 2006-04-28
DE60214527D1 (de) 2006-10-19
RU2300378C2 (ru) 2007-06-10
AU2002226427B2 (en) 2006-11-16
PT1374952E (pt) 2006-12-29
NZ527583A (en) 2006-03-31
MXPA03006411A (es) 2004-12-02
CR7049A (es) 2008-02-20
BR0206549A (pt) 2004-02-25
IL156798A0 (en) 2004-02-08
ATE338575T1 (de) 2006-09-15
KR100712570B1 (ko) 2007-05-02
DK1374952T3 (da) 2007-01-02
CY1107500T1 (el) 2013-03-13
EP1374952A1 (en) 2004-01-02
US20040092509A1 (en) 2004-05-13
ES2269661T3 (es) 2007-04-01
JP2004519461A (ja) 2004-07-02
EP1374952B1 (en) 2006-09-06
ZA200305922B (en) 2004-08-02
JP2008201796A (ja) 2008-09-04
CN1486205A (zh) 2004-03-31
KR20040020046A (ko) 2004-03-06
UA78199C2 (en) 2007-03-15
RU2003125274A (ru) 2005-01-20
US20080132492A1 (en) 2008-06-05
DE60214527T2 (de) 2007-04-05
US7348321B2 (en) 2008-03-25
CA2433833A1 (en) 2002-07-25
CA2433833C (en) 2009-06-02
WO2002056964A1 (es) 2002-07-25

Similar Documents

Publication Publication Date Title
CY1107500T1 (el) Η χρηση του φλουμαζενιλ στην αναπτυξη ενος φαρμακου για τη θepαπευτικη αντιμετωπιση της εξαρτησης απο το αλκοολ
NO20101190L (no) Anvendelse av buprenorfin i fremstillingen av et medikament
ZA200405657B (en) Formulation & dosage form for the controlled delivery of therapeutic agents.
BR0206160A (pt) Uso de anticorpos anti-tnf como medicamentos no tratamento de distúrbios sépticos de pacientes anêmicos
DK0713701T3 (da) 2-Brommelatonin til behandling af søvnforstyrrelser
IL195723A (en) Use of p53 inhibitors for the preparation of medicament
CY1106845T1 (el) Χρηση της φλουμαζενιλης για την παρασκευη ενος φαρμακου για την αγωγη της εξαρτησεως απο την κοκαϊνη
EE05404B1 (et) Kinuklidiini derivaat, selle saamine ja kasutamine ravimi valmistamiseks, mis on ette n„htud respiratoorsete, kuseelundite v?i mao-soolte haiguste ravimiseks, ning seda sisaldav ravimkompositsioon
DE60126923D1 (de) Therapeutische zusammensetzungen bestehend aus antihypotensiva und antiangiogenika
BR0015974A (pt) Uso de levetiracetam, composição farmacêutica, uso de uma composição farmacêutica e métodos para tratar um paciente admintstrado com uma quantidade de pelo menos um composto e uma doença e para potenciar seletivamente o efeito terapêutico de um composto
PT913156E (pt) Utilizacao de proteina c activada para tratar estados hipercoagulaveis associados com sepsia
EE200200107A (et) Kiire algtoimega selektiivse serotoniini tagasihaaramise inhibiitori kasutamine ravimi valmistamiseks, mis on ette nähtud seksuaalse funktsioonihäireravimiseks
NO20042208L (no) Vaginalt administrerte anti-dysrytmiske midler for behandling av bekkensmerter
HK1068606A1 (en) Novel aminobenzoephenones
DK0501705T3 (da) Anvendelse af tomoxetin til behandling af sygdomme i de nedre urinveje
YU42298A (sh) Upotreba olanzapina za pripremanje leka korisnog kod akutnog bola
EE200100689A (et) IL6RIL6 kimääri kasutamine ravimi valmistamiseks,mis on ette nähtud neuroloogiliste haiguste ravimiseks, ning farmatseutiline kompositsioon
SE9902597D0 (sv) New use
WO2001060278A3 (en) Oral therapeutic delivery appliance
BR0211323A (pt) Combinação de ingredientes ativos, uso de uma combinação de ingredientes ativos e método de terapia farmacológica de dependência de nicotina
ATE337790T1 (de) Verwendung von cortisol-sequestriermitteln zur behandlung von hypercortisolaemie-verwandten erkrankungen
DK0872239T3 (da) Anvendelse af olanzapin til fremstilling af et lægemiddel til behandling af cerebral fokal iskæmi
SE9803623D0 (sv) New therapeutic application
PT872238E (pt) Utilizacao de olanzapina para o fabrico de um medicamento para neuroproteccao
UA36361A (uk) Спосіб лікування захворювань щитовидної залози

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130110