HK1040926B - 回腸膽汁酸輸送抑制物與纖維酸衍生物的組合作心血管病指徵 - Google Patents
回腸膽汁酸輸送抑制物與纖維酸衍生物的組合作心血管病指徵Info
- Publication number
- HK1040926B HK1040926B HK02102722.9A HK02102722A HK1040926B HK 1040926 B HK1040926 B HK 1040926B HK 02102722 A HK02102722 A HK 02102722A HK 1040926 B HK1040926 B HK 1040926B
- Authority
- HK
- Hong Kong
- Prior art keywords
- combinations
- transport inhibitors
- ileal bile
- cardiovascular indications
- acid derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11395598P | 1998-12-23 | 1998-12-23 | |
| US14260399P | 1999-07-07 | 1999-07-07 | |
| PCT/US1999/027948 WO2000038727A1 (en) | 1998-12-23 | 1999-12-17 | Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1040926A1 HK1040926A1 (en) | 2002-06-28 |
| HK1040926B true HK1040926B (zh) | 2003-10-17 |
Family
ID=26811676
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02102722.9A HK1040926B (zh) | 1998-12-23 | 2002-04-10 | 回腸膽汁酸輸送抑制物與纖維酸衍生物的組合作心血管病指徵 |
| HK02106673.9A HK1045114A1 (zh) | 1998-12-23 | 2002-09-11 | 適用於心血管疾病的回腸胆汁酸轉運抑制劑和貝酸衍生物的組合 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02106673.9A HK1045114A1 (zh) | 1998-12-23 | 2002-09-11 | 適用於心血管疾病的回腸胆汁酸轉運抑制劑和貝酸衍生物的組合 |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US6638969B1 (zh) |
| EP (2) | EP1140189B1 (zh) |
| JP (1) | JP2002533413A (zh) |
| KR (1) | KR20010102964A (zh) |
| CN (1) | CN1342090A (zh) |
| AR (1) | AR022023A1 (zh) |
| AT (1) | ATE240120T1 (zh) |
| AU (1) | AU776658B2 (zh) |
| BR (1) | BR9916565A (zh) |
| CA (1) | CA2356607A1 (zh) |
| CZ (1) | CZ20012342A3 (zh) |
| DE (1) | DE69907960T2 (zh) |
| DK (1) | DK1140189T3 (zh) |
| EA (1) | EA200100707A1 (zh) |
| ES (1) | ES2200588T3 (zh) |
| HK (2) | HK1040926B (zh) |
| HU (1) | HUP0104793A2 (zh) |
| IL (1) | IL143947A0 (zh) |
| MX (1) | MXPA01006472A (zh) |
| NO (1) | NO20013162L (zh) |
| NZ (1) | NZ512537A (zh) |
| PL (1) | PL348580A1 (zh) |
| PT (1) | PT1140189E (zh) |
| WO (1) | WO2000038727A1 (zh) |
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| SE0000772D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
| EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
| EP1911462A3 (en) | 2001-01-26 | 2011-11-30 | Schering Corporation | Compositions comprising a sterol absorption inhibitor |
| GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
| GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
| MY131995A (en) | 2001-09-08 | 2007-09-28 | Astrazeneca Ab | Benzothiazepine and benzothiadiazepine derivatives with illeal bile acid transport (ibat) inhibitory activity for the treatment hyperlipidaemia |
| GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
| GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
| GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| EP1918000A2 (en) | 2003-11-05 | 2008-05-07 | Schering Corporation | Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions |
| JP4711953B2 (ja) * | 2004-02-27 | 2011-06-29 | 旭化成ファーマ株式会社 | 新規なベンゾチアゼピン及びベンゾチエピン化合物 |
| ES2435790T3 (es) | 2004-12-03 | 2013-12-23 | Intervet International B.V. | Piperazinas sustituidas como antagonistas de CB1 |
| AR059021A1 (es) | 2006-01-18 | 2008-03-05 | Schering Corp | Moduladores de receptores cannabinoides |
| BRPI0621942A2 (pt) | 2006-08-04 | 2011-10-18 | Aska Pharm Co Ltd | preparação que reduz uma concentração de um ácido graxo livre e/ou fibrinogênio no sangue, agente para redução da quantidade de um ácido graxo livre no sangue, agente para redução da quantidade de fibrinogênio no sangue, método de prevenção ou tratamento de hiper-acidemia de ácido graxo livre, sìndrome metabólica, diabetes tipo ii, complicações causadas por diabetes tipo ii, lipotoxicidade, metabolismo anormal de lipìdeos, intoleráncia à glicose, secreção prejudicada de insulina, gordura hepática, lipoproteinemia de hipo-alta densidade, ou trombose, e uso de uma preparação |
| CA2703203C (en) | 2007-10-22 | 2015-12-15 | Schering Corporation | Bicyclic heterocycle derivatives and methods of use thereof |
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| JP7391048B2 (ja) | 2018-06-05 | 2023-12-04 | アルビレオ・アクチボラグ | ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
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-
1999
- 1999-12-17 PT PT99965903T patent/PT1140189E/pt unknown
- 1999-12-17 ES ES99965903T patent/ES2200588T3/es not_active Expired - Lifetime
- 1999-12-17 US US09/465,642 patent/US6638969B1/en not_active Expired - Fee Related
- 1999-12-17 EP EP99965903A patent/EP1140189B1/en not_active Revoked
- 1999-12-17 IL IL14394799A patent/IL143947A0/xx unknown
- 1999-12-17 AT AT99965903T patent/ATE240120T1/de not_active IP Right Cessation
- 1999-12-17 EA EA200100707A patent/EA200100707A1/ru unknown
- 1999-12-17 KR KR1020017008084A patent/KR20010102964A/ko not_active Application Discontinuation
- 1999-12-17 CA CA002356607A patent/CA2356607A1/en not_active Abandoned
- 1999-12-17 JP JP2000590678A patent/JP2002533413A/ja active Pending
- 1999-12-17 BR BR9916565-1A patent/BR9916565A/pt not_active IP Right Cessation
- 1999-12-17 MX MXPA01006472A patent/MXPA01006472A/es unknown
- 1999-12-17 DK DK99965903T patent/DK1140189T3/da active
- 1999-12-17 EP EP03009706A patent/EP1336413A1/en not_active Withdrawn
- 1999-12-17 DE DE69907960T patent/DE69907960T2/de not_active Expired - Fee Related
- 1999-12-17 HU HU0104793A patent/HUP0104793A2/hu unknown
- 1999-12-17 AU AU21579/00A patent/AU776658B2/en not_active Ceased
- 1999-12-17 WO PCT/US1999/027948 patent/WO2000038727A1/en not_active Application Discontinuation
- 1999-12-17 PL PL99348580A patent/PL348580A1/xx not_active Application Discontinuation
- 1999-12-17 NZ NZ512537A patent/NZ512537A/en unknown
- 1999-12-17 CN CN99816270A patent/CN1342090A/zh active Pending
- 1999-12-17 CZ CZ20012342A patent/CZ20012342A3/cs unknown
- 1999-12-23 AR ARP990106754A patent/AR022023A1/es not_active Application Discontinuation
-
2001
- 2001-06-22 NO NO20013162A patent/NO20013162L/no not_active Application Discontinuation
-
2002
- 2002-04-10 HK HK02102722.9A patent/HK1040926B/zh not_active IP Right Cessation
- 2002-09-11 HK HK02106673.9A patent/HK1045114A1/zh unknown
-
2003
- 2003-09-02 US US10/652,306 patent/US20040048846A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU776658B2 (en) | 2004-09-16 |
| JP2002533413A (ja) | 2002-10-08 |
| EP1336413A1 (en) | 2003-08-20 |
| ES2200588T3 (es) | 2004-03-01 |
| NO20013162D0 (no) | 2001-06-22 |
| HUP0104793A2 (en) | 2002-06-29 |
| ATE240120T1 (de) | 2003-05-15 |
| AR022023A1 (es) | 2002-09-04 |
| HK1045114A1 (zh) | 2002-11-15 |
| AU2157900A (en) | 2000-07-31 |
| KR20010102964A (ko) | 2001-11-17 |
| DE69907960T2 (de) | 2004-02-26 |
| WO2000038727A1 (en) | 2000-07-06 |
| PT1140189E (pt) | 2003-09-30 |
| EP1140189B1 (en) | 2003-05-14 |
| CZ20012342A3 (cs) | 2001-12-12 |
| US20040048846A1 (en) | 2004-03-11 |
| MXPA01006472A (es) | 2004-03-10 |
| NO20013162L (no) | 2001-08-21 |
| CA2356607A1 (en) | 2000-07-06 |
| DK1140189T3 (da) | 2003-09-15 |
| NZ512537A (en) | 2003-11-28 |
| DE69907960D1 (de) | 2003-06-18 |
| CN1342090A (zh) | 2002-03-27 |
| EP1140189A1 (en) | 2001-10-10 |
| US6638969B1 (en) | 2003-10-28 |
| IL143947A0 (en) | 2002-04-21 |
| BR9916565A (pt) | 2002-01-29 |
| PL348580A1 (en) | 2002-06-03 |
| HK1040926A1 (en) | 2002-06-28 |
| EA200100707A1 (ru) | 2001-12-24 |
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| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20061217 |