HK1027812A1 - (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents - Google Patents

(4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents

Info

Publication number
HK1027812A1
HK1027812A1 HK00107146A HK00107146A HK1027812A1 HK 1027812 A1 HK1027812 A1 HK 1027812A1 HK 00107146 A HK00107146 A HK 00107146A HK 00107146 A HK00107146 A HK 00107146A HK 1027812 A1 HK1027812 A1 HK 1027812A1
Authority
HK
Hong Kong
Prior art keywords
piperidinyl
derivatives useful
antipsychotic agents
benzopyran derivatives
benzopyran
Prior art date
Application number
HK00107146A
Other languages
English (en)
Inventor
Joseph T Strupczewski
Kenneth J Bordeau
Shelley L Pavlek
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of HK1027812A1 publication Critical patent/HK1027812A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK00107146A 1997-02-07 2000-11-09 (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents HK1027812A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79710797A 1997-02-07 1997-02-07
PCT/US1998/000979 WO1998034933A1 (en) 1997-02-07 1998-01-20 (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents

Publications (1)

Publication Number Publication Date
HK1027812A1 true HK1027812A1 (en) 2001-01-23

Family

ID=25169927

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00107146A HK1027812A1 (en) 1997-02-07 2000-11-09 (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents

Country Status (22)

Country Link
EP (1) EP1015446B1 (xx)
JP (1) JP4177461B2 (xx)
KR (1) KR100509878B1 (xx)
CN (1) CN1092653C (xx)
AR (1) AR011614A1 (xx)
AT (1) ATE236150T1 (xx)
AU (1) AU725301B2 (xx)
BR (1) BRPI9807312B8 (xx)
CA (1) CA2281702C (xx)
CY (1) CY2324B1 (xx)
DE (1) DE69812980T2 (xx)
DK (1) DK1015446T3 (xx)
ES (1) ES2194303T3 (xx)
HK (1) HK1027812A1 (xx)
HU (1) HUP0001308A3 (xx)
IL (1) IL131243A (xx)
NO (1) NO318936B1 (xx)
NZ (1) NZ336719A (xx)
PT (1) PT1015446E (xx)
TW (1) TW518333B (xx)
WO (1) WO1998034933A1 (xx)
ZA (1) ZA98831B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2342083T3 (es) * 2004-04-29 2010-07-01 Aventis Pharmaceuticals Inc. 3-piperidinilisocroman-5-oles como agonistas de dopamina.
EP1748767B1 (en) 2004-05-28 2011-12-28 Unigen, Inc. 1-(3-methyl-2,4-dimethoxyphenyl)-3-(2',4'-dihydroxyphenyl)-propane as a potent tyrosinase inhibitor
CN101778844B (zh) 2007-07-26 2013-01-02 弗·哈夫曼-拉罗切有限公司 5-ht2a和d3受体的双重调节剂
BRPI0916188A2 (pt) 2008-07-21 2017-08-29 Unigen Inc Série de composto para clareamento da pele (iluminação)
US8877778B2 (en) 2010-12-15 2014-11-04 Hoffmann-La Roche Inc. Benzofurane compounds
CN102079720B (zh) * 2011-01-20 2013-02-06 蚌埠丰原医药科技发展有限公司 一种制备1-苄基-4-哌啶甲醛的方法
KR101976642B1 (ko) 2011-03-24 2019-05-09 유니젠, 인크. 디아릴프로판의 제조를 위한 화합물 및 방법
US8921397B2 (en) 2011-05-04 2014-12-30 Hoffmann-La Roche Inc. Benzofurane-piperidine compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
US4963568A (en) * 1989-05-31 1990-10-16 Abbott Laboratories Dopamine agonists

Also Published As

Publication number Publication date
BR9807312B1 (pt) 2013-10-29
NO993812L (no) 1999-10-05
CA2281702C (en) 2006-04-11
CY2324B1 (en) 2003-11-14
AU725301B2 (en) 2000-10-12
AR011614A1 (es) 2000-08-30
DE69812980T2 (de) 2003-11-13
PT1015446E (pt) 2003-08-29
EP1015446A1 (en) 2000-07-05
EP1015446B1 (en) 2003-04-02
KR20000070862A (ko) 2000-11-25
ES2194303T3 (es) 2003-11-16
BRPI9807312B8 (pt) 2016-09-13
HUP0001308A2 (hu) 2001-06-28
HUP0001308A3 (en) 2001-07-30
TW518333B (en) 2003-01-21
IL131243A0 (en) 2001-01-28
WO1998034933A1 (en) 1998-08-13
IL131243A (en) 2004-02-19
KR100509878B1 (ko) 2005-08-25
NZ336719A (en) 2000-10-27
JP2001512436A (ja) 2001-08-21
CN1092653C (zh) 2002-10-16
BR9807312A (pt) 2000-05-02
ZA98831B (en) 1998-08-07
NO318936B1 (no) 2005-05-30
ATE236150T1 (de) 2003-04-15
CA2281702A1 (en) 1998-08-13
NO993812D0 (no) 1999-08-06
AU5923798A (en) 1998-08-26
JP4177461B2 (ja) 2008-11-05
DE69812980D1 (de) 2003-05-08
DK1015446T3 (da) 2003-07-14
CN1246859A (zh) 2000-03-08

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080120