PT1015446E - Derivados de (4-piperidinil)-1h-2-benzopirano uteis como agentes antipsicoticos - Google Patents

Derivados de (4-piperidinil)-1h-2-benzopirano uteis como agentes antipsicoticos

Info

Publication number
PT1015446E
PT1015446E PT98902628T PT98902628T PT1015446E PT 1015446 E PT1015446 E PT 1015446E PT 98902628 T PT98902628 T PT 98902628T PT 98902628 T PT98902628 T PT 98902628T PT 1015446 E PT1015446 E PT 1015446E
Authority
PT
Portugal
Prior art keywords
psychostic
benzopyranean
piperidinyl
derivatives
agents
Prior art date
Application number
PT98902628T
Other languages
English (en)
Inventor
Shelley L Pavlek
Joseph T Strupczewski
Kenneth J Bordeau
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of PT1015446E publication Critical patent/PT1015446E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PT98902628T 1997-02-07 1998-01-20 Derivados de (4-piperidinil)-1h-2-benzopirano uteis como agentes antipsicoticos PT1015446E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79710797A 1997-02-07 1997-02-07

Publications (1)

Publication Number Publication Date
PT1015446E true PT1015446E (pt) 2003-08-29

Family

ID=25169927

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98902628T PT1015446E (pt) 1997-02-07 1998-01-20 Derivados de (4-piperidinil)-1h-2-benzopirano uteis como agentes antipsicoticos

Country Status (22)

Country Link
EP (1) EP1015446B1 (pt)
JP (1) JP4177461B2 (pt)
KR (1) KR100509878B1 (pt)
CN (1) CN1092653C (pt)
AR (1) AR011614A1 (pt)
AT (1) ATE236150T1 (pt)
AU (1) AU725301B2 (pt)
BR (1) BRPI9807312B8 (pt)
CA (1) CA2281702C (pt)
CY (1) CY2324B1 (pt)
DE (1) DE69812980T2 (pt)
DK (1) DK1015446T3 (pt)
ES (1) ES2194303T3 (pt)
HK (1) HK1027812A1 (pt)
HU (1) HUP0001308A3 (pt)
IL (1) IL131243A (pt)
NO (1) NO318936B1 (pt)
NZ (1) NZ336719A (pt)
PT (1) PT1015446E (pt)
TW (1) TW518333B (pt)
WO (1) WO1998034933A1 (pt)
ZA (1) ZA98831B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005111025A1 (en) * 2004-04-29 2005-11-24 Aventis Pharmaceuticals Inc. 3-piperidinylisochroman-5-ols as dopamine agonists
JP5128277B2 (ja) 2004-05-28 2013-01-23 ユニジェン・インコーポレーテッド 二核酵素の強力な阻害剤としてのジアリールアルカン類
JP5502733B2 (ja) 2007-07-26 2014-05-28 エフ.ホフマン−ラ ロシュ アーゲー 5−ht2a及びd3受容体の二重のモジュレーター
KR101849695B1 (ko) 2008-07-21 2018-04-17 유니젠, 인크. 일련의 피부-화이트닝(라이트닝) 화합물
US8877778B2 (en) 2010-12-15 2014-11-04 Hoffmann-La Roche Inc. Benzofurane compounds
CN102079720B (zh) * 2011-01-20 2013-02-06 蚌埠丰原医药科技发展有限公司 一种制备1-苄基-4-哌啶甲醛的方法
CA2830993C (en) 2011-03-24 2019-07-02 Unigen, Inc. Compounds and methods for preparation of diarylpropanes
US8921397B2 (en) 2011-05-04 2014-12-30 Hoffmann-La Roche Inc. Benzofurane-piperidine compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
US4963568A (en) * 1989-05-31 1990-10-16 Abbott Laboratories Dopamine agonists

Also Published As

Publication number Publication date
CN1092653C (zh) 2002-10-16
ZA98831B (en) 1998-08-07
DE69812980T2 (de) 2003-11-13
BR9807312A (pt) 2000-05-02
DK1015446T3 (da) 2003-07-14
AU725301B2 (en) 2000-10-12
CN1246859A (zh) 2000-03-08
WO1998034933A1 (en) 1998-08-13
DE69812980D1 (de) 2003-05-08
HK1027812A1 (en) 2001-01-23
EP1015446B1 (en) 2003-04-02
IL131243A0 (en) 2001-01-28
IL131243A (en) 2004-02-19
KR100509878B1 (ko) 2005-08-25
TW518333B (en) 2003-01-21
KR20000070862A (ko) 2000-11-25
JP2001512436A (ja) 2001-08-21
CA2281702C (en) 2006-04-11
HUP0001308A3 (en) 2001-07-30
EP1015446A1 (en) 2000-07-05
NO318936B1 (no) 2005-05-30
AR011614A1 (es) 2000-08-30
CA2281702A1 (en) 1998-08-13
AU5923798A (en) 1998-08-26
HUP0001308A2 (hu) 2001-06-28
ES2194303T3 (es) 2003-11-16
NZ336719A (en) 2000-10-27
NO993812D0 (no) 1999-08-06
CY2324B1 (en) 2003-11-14
JP4177461B2 (ja) 2008-11-05
BRPI9807312B8 (pt) 2016-09-13
ATE236150T1 (de) 2003-04-15
BR9807312B1 (pt) 2013-10-29
NO993812L (no) 1999-10-05

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