US7279561B1
(en)
*
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
ES2176245T3
(es)
|
1993-04-23 |
2002-12-01 |
Wyeth Corp |
Anticuerpos de ramapicinas de ciclo abierto.
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
BE1009856A5
(fr)
|
1995-07-14 |
1997-10-07 |
Sandoz Sa |
Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
|
GB9606452D0
(en)
*
|
1996-03-27 |
1996-06-05 |
Sandoz Ltd |
Organic compounds
|
WO1998002441A2
(en)
*
|
1996-07-12 |
1998-01-22 |
Ariad Pharmaceuticals, Inc. |
Non immunosuppressive antifungal rapalogs
|
US20050031611A1
(en)
*
|
1998-05-08 |
2005-02-10 |
Beth Israel Deaconess Medical Center |
Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis
|
GB9826882D0
(en)
*
|
1998-12-07 |
1999-01-27 |
Novartis Ag |
Organic compounds
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
EP1158985B1
(en)
|
1999-01-13 |
2011-12-28 |
Bayer HealthCare LLC |
OMEGA-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS
|
US6955661B1
(en)
*
|
1999-01-25 |
2005-10-18 |
Atrium Medical Corporation |
Expandable fluoropolymer device for delivery of therapeutic agents and method of making
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
EP1212331B1
(en)
|
1999-08-24 |
2004-04-21 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
US6790228B2
(en)
|
1999-12-23 |
2004-09-14 |
Advanced Cardiovascular Systems, Inc. |
Coating for implantable devices and a method of forming the same
|
US20070032853A1
(en)
|
2002-03-27 |
2007-02-08 |
Hossainy Syed F |
40-O-(2-hydroxy)ethyl-rapamycin coated stent
|
US7807211B2
(en)
|
1999-09-03 |
2010-10-05 |
Advanced Cardiovascular Systems, Inc. |
Thermal treatment of an implantable medical device
|
US6277983B1
(en)
|
2000-09-27 |
2001-08-21 |
American Home Products Corporation |
Regioselective synthesis of rapamycin derivatives
|
US6670355B2
(en)
*
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
US6399626B1
(en)
*
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
US20040018228A1
(en)
*
|
2000-11-06 |
2004-01-29 |
Afmedica, Inc. |
Compositions and methods for reducing scar tissue formation
|
US20040241211A9
(en)
*
|
2000-11-06 |
2004-12-02 |
Fischell Robert E. |
Devices and methods for reducing scar tissue formation
|
US6534693B2
(en)
|
2000-11-06 |
2003-03-18 |
Afmedica, Inc. |
Surgically implanted devices having reduced scar tissue formation
|
NZ526708A
(en)
|
2000-11-28 |
2005-07-29 |
Wyeth Corp |
Expression analysis of FKBP nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
AU2016206379B2
(en)
*
|
2001-02-19 |
2017-09-14 |
Novartis Ag |
Cancer Treatment
|
EP1363627A2
(en)
*
|
2001-02-19 |
2003-11-26 |
Novartis AG |
Treatment of solid tumours with rapamycin derivatives
|
AU2005201004A1
(en)
*
|
2001-02-19 |
2005-03-24 |
Novartis Ag |
Cancer treatment
|
AU2011226835C1
(en)
*
|
2001-02-19 |
2018-01-04 |
Novartis Ag |
Cancer treatment
|
WO2002096420A2
(en)
*
|
2001-05-29 |
2002-12-05 |
Guilford Pharmaceuticals Inc. |
Method for treating nerve injury caused by surgery
|
DE60129133T2
(de)
*
|
2001-08-13 |
2008-03-06 |
Fondazione Salvatore Maugeri - Clinica del Lavoro e della Riabilitazione |
Verwendung von Clarithromycin zur Herstellung eines Medikaments für die Behandlung von Arthrosis deformans
|
US20030054042A1
(en)
*
|
2001-09-14 |
2003-03-20 |
Elaine Liversidge |
Stabilization of chemical compounds using nanoparticulate formulations
|
PL216224B1
(pl)
*
|
2002-02-01 |
2014-03-31 |
Ariad Pharmaceuticals |
Pochodne rapamycyny zawierające fosfor, kompozycja je zawierająca oraz ich zastosowanie
|
JP4636486B2
(ja)
|
2002-02-11 |
2011-02-23 |
バイエル、ファーマシューテイカルズ、コーポレイション |
脈管形成阻害活性を有するアリール尿素
|
EP1340498A1
(en)
*
|
2002-03-01 |
2003-09-03 |
Schering Aktiengesellschaft |
Use of epothilones in the treatment of brain diseases associated with proliferative processes
|
DK1505959T3
(da)
|
2002-05-16 |
2009-02-23 |
Novartis Ag |
Anvendelse af EDG-receptorbindingsmidler ved cancer
|
JP4265888B2
(ja)
*
|
2002-06-12 |
2009-05-20 |
株式会社リコー |
画像形成装置
|
EP1655372A3
(en)
|
2002-07-16 |
2008-01-16 |
Biotica Technology Limited |
Production of polyketides and other natural products
|
US20060046979A1
(en)
|
2002-09-24 |
2006-03-02 |
Foster Carolyn A |
Organic compounds
|
AU2003293529A1
(en)
|
2002-12-16 |
2004-07-29 |
Nitromed, Inc. |
Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use
|
EP1594459B1
(en)
|
2002-12-30 |
2010-02-17 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
US20070155771A1
(en)
*
|
2003-04-11 |
2007-07-05 |
David Rubinsztein |
Methods and means for treating protein conformational disorders
|
US7160867B2
(en)
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
DK1636585T3
(da)
|
2003-05-20 |
2008-05-26 |
Bayer Pharmaceuticals Corp |
Diarylurinstoffer med kinasehæmmende aktivitet
|
JP4041774B2
(ja)
*
|
2003-06-05 |
2008-01-30 |
住友金属工業株式会社 |
β型チタン合金材の製造方法
|
JP4351474B2
(ja)
*
|
2003-06-05 |
2009-10-28 |
住友金属工業株式会社 |
ゴルフクラブヘッドフェース用板材の製造方法およびゴルフクラブヘッド
|
US20050118344A1
(en)
|
2003-12-01 |
2005-06-02 |
Pacetti Stephen D. |
Temperature controlled crimping
|
US8021331B2
(en)
*
|
2003-09-15 |
2011-09-20 |
Atrium Medical Corporation |
Method of coating a folded medical device
|
US7659244B2
(en)
|
2003-11-03 |
2010-02-09 |
Quest Pharmatech, Inc. |
Rapamycin peptides conjugates: synthesis and uses thereof
|
US7220755B2
(en)
*
|
2003-11-12 |
2007-05-22 |
Biosensors International Group, Ltd. |
42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
|
GB0327840D0
(en)
*
|
2003-12-01 |
2003-12-31 |
Novartis Ag |
Organic compounds
|
US20110104186A1
(en)
|
2004-06-24 |
2011-05-05 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
GB0417852D0
(en)
|
2004-08-11 |
2004-09-15 |
Biotica Tech Ltd |
Production of polyketides and other natural products
|
WO2006037080A2
(en)
|
2004-09-28 |
2006-04-06 |
Atrium Medical Corporation |
Uv cured gel and method of making
|
US9012506B2
(en)
|
2004-09-28 |
2015-04-21 |
Atrium Medical Corporation |
Cross-linked fatty acid-based biomaterials
|
US9000040B2
(en)
|
2004-09-28 |
2015-04-07 |
Atrium Medical Corporation |
Cross-linked fatty acid-based biomaterials
|
US8021849B2
(en)
*
|
2004-11-05 |
2011-09-20 |
Siemens Healthcare Diagnostics Inc. |
Methods and kits for the determination of sirolimus in a sample
|
WO2006053754A1
(en)
*
|
2004-11-19 |
2006-05-26 |
Novartis Ag |
COMBINATIONS OF ANTI-ATHEROSCLEROTIC PEPTIDES AND AN mTOR INHIBITING AGENT AND THEIR METHODS OF USE
|
GB0504544D0
(en)
|
2005-03-04 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
KR20070116868A
(ko)
|
2005-03-11 |
2007-12-11 |
바이오티카 테크놀로지 리미티드 |
39데스메톡시라파마이신 및 그 유사체의 의학적 용도
|
GB0504994D0
(en)
|
2005-03-11 |
2005-04-20 |
Biotica Tech Ltd |
Novel compounds
|
US7189582B2
(en)
*
|
2005-04-27 |
2007-03-13 |
Dade Behring Inc. |
Compositions and methods for detection of sirolimus
|
BRPI0611021A2
(pt)
*
|
2005-05-31 |
2010-08-10 |
Novartis Ag |
combinação de inibidores de hmg-coa redutase e inibidores de mtor
|
US20090062909A1
(en)
|
2005-07-15 |
2009-03-05 |
Micell Technologies, Inc. |
Stent with polymer coating containing amorphous rapamycin
|
ES2691646T3
(es)
|
2005-07-15 |
2018-11-28 |
Micell Technologies, Inc. |
Revestimientos poliméricos que contienen polvo de fármaco de morfología controlada
|
RU2443418C2
(ru)
|
2005-07-20 |
2012-02-27 |
Новартис Аг |
КОМБИНАЦИЯ ПИРИМИДИЛАМИНОБЕНЗАМИДА И ИНГИБИТОРА КИНАЗ mTOR
|
WO2007014278A2
(en)
|
2005-07-25 |
2007-02-01 |
Trubion Pharmaceuticals, Inc. |
B-cell reduction using cd37-specific and cd20-specific binding molecules
|
AU2006284922B2
(en)
|
2005-08-30 |
2012-01-19 |
University Of Miami |
Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins
|
US9278161B2
(en)
|
2005-09-28 |
2016-03-08 |
Atrium Medical Corporation |
Tissue-separating fatty acid adhesion barrier
|
US9427423B2
(en)
|
2009-03-10 |
2016-08-30 |
Atrium Medical Corporation |
Fatty-acid based particles
|
US20070134739A1
(en)
*
|
2005-12-12 |
2007-06-14 |
Gyros Patent Ab |
Microfluidic assays and microfluidic devices
|
GB0601406D0
(en)
*
|
2006-01-24 |
2006-03-08 |
Novartis Ag |
Organic Compounds
|
RU2473343C2
(ru)
*
|
2006-02-02 |
2013-01-27 |
Новартис Аг |
Лечение туберозного склероза
|
ES2540059T3
(es)
|
2006-04-26 |
2015-07-08 |
Micell Technologies, Inc. |
Recubrimientos que contienen múltiples fármacos
|
EP2056821A2
(en)
*
|
2006-08-22 |
2009-05-13 |
Novartis AG |
Rapamycin and its derivatives for the treatment of liver-associated fibrosing disorders
|
US8088789B2
(en)
|
2006-09-13 |
2012-01-03 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
US10695327B2
(en)
|
2006-09-13 |
2020-06-30 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
CN104906087A
(zh)
|
2006-09-13 |
2015-09-16 |
万能医药公司 |
大环内酯化合物及它们的使用方法
|
EP2090580B1
(en)
*
|
2006-11-27 |
2014-06-04 |
Terumo Kabushiki Kaisha |
Process for producing o-alkylated rapamycin derivative, and o-alkylated rapamycin derivative
|
US11426494B2
(en)
|
2007-01-08 |
2022-08-30 |
MT Acquisition Holdings LLC |
Stents having biodegradable layers
|
JP5603598B2
(ja)
|
2007-01-08 |
2014-10-08 |
ミセル テクノロジーズ、インコーポレイテッド |
生物分解層を有するステント
|
US7938286B2
(en)
*
|
2007-02-13 |
2011-05-10 |
Gateway Plastics, Inc. |
Container system
|
WO2009089549A1
(en)
|
2008-01-11 |
2009-07-16 |
Massachusetts Eye & Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
US20100048913A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
US20090253733A1
(en)
*
|
2008-04-02 |
2009-10-08 |
Biointeractions, Ltd. |
Rapamycin carbonate esters
|
CN102099377A
(zh)
|
2008-04-11 |
2011-06-15 |
新兴产品开发西雅图有限公司 |
Cd37免疫治疗剂及其与双功能化学治疗剂的联合
|
CA2721832C
(en)
|
2008-04-17 |
2018-08-07 |
Micell Technologies, Inc. |
Stents having bioabsorbable layers
|
EP3545953A1
(en)
|
2008-06-20 |
2019-10-02 |
Novartis AG |
Paediatric compositions for treating1 multiple sclerosis
|
US9510856B2
(en)
|
2008-07-17 |
2016-12-06 |
Micell Technologies, Inc. |
Drug delivery medical device
|
AU2009270849B2
(en)
|
2008-07-17 |
2013-11-21 |
Micell Technologies, Inc. |
Drug delivery medical device
|
US20100086579A1
(en)
*
|
2008-10-03 |
2010-04-08 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
DK2365802T3
(da)
|
2008-11-11 |
2017-11-13 |
Univ Texas |
Mikrokapsler af rapamycin og anvendelse til behandling af cancer
|
DE102008060549A1
(de)
|
2008-12-04 |
2010-06-10 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
|
EP3023433A1
(en)
|
2009-02-05 |
2016-05-25 |
Tokai Pharmaceuticals, Inc. |
Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
|
CA2757276C
(en)
|
2009-04-01 |
2017-06-06 |
Micell Technologies, Inc. |
Coated stents
|
WO2010121187A2
(en)
|
2009-04-17 |
2010-10-21 |
Micell Techologies, Inc. |
Stents having controlled elution
|
ES2586837T3
(es)
|
2009-08-03 |
2016-10-19 |
University Of Miami |
Método para la expansión in vivo de linfocitos T reguladores
|
US20110038910A1
(en)
|
2009-08-11 |
2011-02-17 |
Atrium Medical Corporation |
Anti-infective antimicrobial-containing biomaterials
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
US20170079962A1
(en)
|
2009-11-11 |
2017-03-23 |
Rapamycin Holdings, Llc |
Oral Rapamycin Preparation and Use for Stomatitus
|
US11369498B2
(en)
|
2010-02-02 |
2022-06-28 |
MT Acquisition Holdings LLC |
Stent and stent delivery system with improved deliverability
|
ES2689177T3
(es)
|
2010-04-13 |
2018-11-08 |
Novartis Ag |
Combinación que comprende un inhibidor de cinasa 4 dependiente de ciclina o cinasa dependiente de ciclina (CDK4/6) y un inhibidor de mTOR para tratar cáncer
|
NZ602807A
(en)
|
2010-04-16 |
2014-02-28 |
Novartis Ag |
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one and an mtor inhibitor
|
EP2560576B1
(en)
|
2010-04-22 |
2018-07-18 |
Micell Technologies, Inc. |
Stents and other devices having extracellular matrix coating
|
EP2563391B1
(en)
|
2010-04-27 |
2020-08-26 |
Roche Glycart AG |
Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor
|
US20130172853A1
(en)
|
2010-07-16 |
2013-07-04 |
Micell Technologies, Inc. |
Drug delivery medical device
|
EP2593141B1
(en)
|
2010-07-16 |
2018-07-04 |
Atrium Medical Corporation |
Composition and methods for altering the rate of hydrolysis of cured oil-based materials
|
EP2675451B9
(en)
|
2011-02-18 |
2017-07-26 |
Novartis Pharma AG |
mTOR/JAK INHIBITOR COMBINATION THERAPY
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
PE20140601A1
(es)
|
2011-04-25 |
2014-05-24 |
Novartis Ag |
COMBINACION DE UN INHIBIDOR DE CINASA DE FOSFATIDIL-INOSITOL-3 (PI3K) Y UN INHIBIDOR DE mTOR
|
CA2841360A1
(en)
|
2011-07-15 |
2013-01-24 |
Micell Technologies, Inc. |
Drug delivery medical device
|
US10188772B2
(en)
|
2011-10-18 |
2019-01-29 |
Micell Technologies, Inc. |
Drug delivery medical device
|
EP2589383A1
(en)
|
2011-11-06 |
2013-05-08 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
FKBP subtype-specific rapamycin analogue for use in treatment of diseases
|
EP2780017A1
(en)
|
2011-11-15 |
2014-09-24 |
Novartis AG |
Combination of a phosphoinositide 3-kinase inhibitor and a modulator of the janus kinase 2-signal transducer and activator of transcription 5 pathway
|
GB201122305D0
(en)
|
2011-12-23 |
2012-02-01 |
Biotica Tech Ltd |
Novel compound
|
US9867880B2
(en)
|
2012-06-13 |
2018-01-16 |
Atrium Medical Corporation |
Cured oil-hydrogel biomaterial compositions for controlled drug delivery
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
WO2014006115A1
(en)
|
2012-07-06 |
2014-01-09 |
Novartis Ag |
Combination of a phosphoinositide 3-kinase inhibitor and an inhibitor of the il-8/cxcr interaction
|
WO2014059295A1
(en)
|
2012-10-12 |
2014-04-17 |
The Board Of Regents Of The University Of Texas System |
Use of mtor inhibitors to treat vascular cognitive impairment
|
EP2919759A4
(en)
|
2012-11-14 |
2016-07-20 |
Ohio State Innovation Foundation |
MATERIALS AND METHODS FOR THE TREATMENT OF GLIOBLASTOMES
|
CA2897826C
(en)
|
2013-01-09 |
2022-09-27 |
Taylor H. Schreiber |
Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein
|
JP6330024B2
(ja)
|
2013-03-12 |
2018-05-23 |
マイセル・テクノロジーズ,インコーポレイテッド |
生体吸収性バイオメディカルインプラント
|
EP2968281B1
(en)
|
2013-03-13 |
2020-08-05 |
The Board of Regents of The University of Texas System |
Mtor inhibitors for prevention of intestinal polyp growth
|
KR20150127720A
(ko)
|
2013-03-14 |
2015-11-17 |
유니버시티 오브 매릴랜드, 발티모어 |
안드로겐 수용체 하향 조절제 및 그의 용도
|
WO2014182635A1
(en)
|
2013-05-08 |
2014-11-13 |
Baldwin Megan E |
Biomarkers for age-related macular degeneration (amd)
|
WO2014186532A1
(en)
|
2013-05-15 |
2014-11-20 |
Micell Technologies, Inc. |
Bioabsorbable biomedical implants
|
US9593356B2
(en)
|
2013-06-11 |
2017-03-14 |
Takara Bio Usa, Inc. |
Protein enriched microvesicles and methods of making and using the same
|
WO2014203185A1
(en)
*
|
2013-06-20 |
2014-12-24 |
Novartis Ag |
Alkylation with an alkyl fluoroalkyl sulfonate
|
BR112016002970A2
(pt)
|
2013-08-12 |
2017-09-12 |
Tokai Pharmaceuticals Inc |
biomarcadores para o tratamento de distúrbios neoplásicos que usa terapias direcionadas ao androgênio
|
US9580758B2
(en)
|
2013-11-12 |
2017-02-28 |
Luc Montagnier |
System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
|
WO2015073644A1
(en)
|
2013-11-13 |
2015-05-21 |
Novartis Ag |
Mtor inhibitors for enhancing the immune response
|
CA2931684C
(en)
|
2013-12-19 |
2024-02-20 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
US10287354B2
(en)
|
2013-12-20 |
2019-05-14 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
CN103739616B
(zh)
*
|
2013-12-27 |
2015-12-30 |
福建省微生物研究所 |
含噻唑基雷帕霉素类衍生物及其应用
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|
CA2933908C
(en)
|
2013-12-31 |
2024-01-30 |
Rapamycin Holdings, Llc |
Oral rapamycin nanoparticle preparations and use
|
WO2015121795A1
(en)
|
2014-02-11 |
2015-08-20 |
Novartis Ag |
Pharmaceutical combinations comprising a pi3k inhibitor for the treatment of cancer
|
WO2015142661A1
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Regulatable chimeric antigen receptor
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
CA2943609A1
(en)
|
2014-03-27 |
2015-10-01 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
KR102487608B1
(ko)
|
2014-04-07 |
2023-01-12 |
노파르티스 아게 |
항-cd19 키메라 항원 수용체를 사용한 암의 치료
|
WO2015171723A1
(en)
|
2014-05-06 |
2015-11-12 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to glp1 agonist therapy
|
CN106659758A
(zh)
|
2014-06-02 |
2017-05-10 |
儿童医疗中心有限公司 |
用于免疫调节的组合物和方法
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
CN112481283A
(zh)
|
2014-07-21 |
2021-03-12 |
诺华股份有限公司 |
使用cd33嵌合抗原受体治疗癌症
|
ES2781175T3
(es)
|
2014-07-31 |
2020-08-31 |
Novartis Ag |
Subconjunto optimizado de células T que contienen un receptor de antígeno quimérico
|
US10851149B2
(en)
|
2014-08-14 |
2020-12-01 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using GFR α-4 chimeric antigen receptor
|
JP7084138B2
(ja)
|
2014-08-19 |
2022-06-14 |
ノバルティス アーゲー |
癌処置に使用するための抗cd123キメラ抗原受容体(car)
|
WO2016040806A1
(en)
|
2014-09-11 |
2016-03-17 |
The Regents Of The University Of California |
mTORC1 INHIBITORS
|
CN114621969A
(zh)
|
2014-09-17 |
2022-06-14 |
诺华股份有限公司 |
用于过继免疫疗法的具有嵌合受体的靶向细胞毒性细胞
|
AU2015330898B2
(en)
|
2014-10-08 |
2022-03-10 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
WO2016066608A1
(en)
|
2014-10-28 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treatment of pulmonary cell senescence and peripheral aging
|
ES2876974T3
(es)
|
2015-04-07 |
2021-11-15 |
Novartis Ag |
Combinación de terapia con receptor de antígeno quimérico y derivados de amino pirimidina
|
EP4234685A3
(en)
|
2015-04-17 |
2023-09-06 |
Novartis AG |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
JP6857141B2
(ja)
|
2015-05-20 |
2021-04-14 |
ノバルティス アーゲー |
エベロリムスとダクトリシブとの薬学的組合せ
|
AU2016352806A1
(en)
|
2015-11-11 |
2018-05-10 |
Novartis Ag |
Uses of myostatin antagonists, combinations containing them and uses thereof
|
EP4014967A1
(en)
|
2016-04-29 |
2022-06-22 |
Icahn School of Medicine at Mount Sinai |
Targeting the innate immunesystem to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis
|
CA3031542A1
(en)
|
2016-07-20 |
2018-01-25 |
University Of Utah Research Foundation |
Cd229 car t cells and methods of use thereof
|
AR110676A1
(es)
|
2016-10-07 |
2019-04-24 |
Novartis Ag |
Tratamiento del cáncer utilizando receptores de antígenos quiméricos
|
CN110114070A
(zh)
|
2016-11-23 |
2019-08-09 |
诺华公司 |
使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法
|
EP3548894B1
(en)
|
2016-12-02 |
2021-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for diagnosing renal cell carcinoma
|
HUE056777T2
(hu)
|
2016-12-22 |
2022-03-28 |
Amgen Inc |
Benzizotiazol-, izotiazolo[3,4-b]piridin-, kinazolin-, ftálazin-, pirido[2,3-d]piridazin- és pirido[2,3-d]pirimidin-származékok mint KRAS G12C inhibitorok tüdõ-, hasnyálmirigy- vagy vastagbélrák kezelésére
|
CN110603038A
(zh)
|
2017-02-10 |
2019-12-20 |
塔姆山治疗公司 |
雷帕霉素类似物
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
WO2018213352A1
(en)
|
2017-05-15 |
2018-11-22 |
C.R. Bard, Inc. |
Medical device with drug-eluting coating and intermediate layer
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
UY37870A
(es)
|
2017-09-08 |
2019-03-29 |
Amgen Inc |
Inhibidores de kras g12c y métodos para utilizarlos campo de la invención
|
AR112834A1
(es)
|
2017-09-26 |
2019-12-18 |
Novartis Ag |
Derivados de rapamicina
|
US10596165B2
(en)
|
2018-02-12 |
2020-03-24 |
resTORbio, Inc. |
Combination therapies
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
CA3098692A1
(en)
|
2018-05-01 |
2019-11-07 |
Revolution Medicines, Inc. |
C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors
|
AU2019262979B2
(en)
|
2018-05-01 |
2023-07-06 |
Revolution Medicines, Inc. |
C26-linked rapamycin analogs as mTOR inhibitors
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
MA52501A
(fr)
|
2018-05-04 |
2021-03-10 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
JP7361722B2
(ja)
|
2018-05-04 |
2023-10-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤及び同一物の使用方法
|
EP3790886A1
(en)
|
2018-05-10 |
2021-03-17 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
WO2019232419A1
(en)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
MX2020012204A
(es)
|
2018-06-11 |
2021-03-31 |
Amgen Inc |
Inhibidores de kras g12c para tratar el cáncer.
|
MA51848A
(fr)
|
2018-06-12 |
2021-04-21 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
US10980784B2
(en)
|
2018-06-15 |
2021-04-20 |
Navitor Pharmaceuticals, Inc. |
Rapamycin analogs and uses thereof
|
WO2020101675A1
(en)
|
2018-11-14 |
2020-05-22 |
Lutonix, Inc. |
Medical device with drug-eluting coating on modified device surface
|
JP2020090482A
(ja)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
WO2020106640A1
(en)
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
EP3898616A1
(en)
|
2018-12-20 |
2021-10-27 |
Amgen Inc. |
Heteroaryl amides useful as kif18a inhibitors
|
CA3123044A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Heteroaryl amides useful as kif18a inhibitors
|
MA54543A
(fr)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
Inhibiteurs de kif18a
|
CA3123042A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
MX2021010319A
(es)
|
2019-03-01 |
2021-12-10 |
Revolution Medicines Inc |
Compuestos biciclicos de heteroarilo y usos de estos.
|
CA3130083A1
(en)
|
2019-03-01 |
2020-09-10 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
CN113939324A
(zh)
|
2019-04-08 |
2022-01-14 |
巴德外周血管股份有限公司 |
在经改性装置表面上具有药物洗脱涂层的医疗装置
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
CA3140392A1
(en)
|
2019-05-21 |
2020-11-26 |
Amgen Inc. |
Solid state forms
|
TW202114681A
(zh)
|
2019-07-02 |
2021-04-16 |
美商eFFECTOR醫療公司 |
轉譯抑制劑及其用途
|
WO2021026100A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Pyridine derivatives as kif18a inhibitors
|
WO2021026099A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
JP2022542967A
(ja)
|
2019-08-02 |
2022-10-07 |
アムジエン・インコーポレーテツド |
Kif18a阻害剤
|
CN114269731A
(zh)
|
2019-08-02 |
2022-04-01 |
美国安进公司 |
Kif18a抑制剂
|
WO2021055728A1
(en)
|
2019-09-18 |
2021-03-25 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
MX2022004656A
(es)
|
2019-10-24 |
2022-05-25 |
Amgen Inc |
Derivados de piridopirimidina utiles como inhibidores de kras g12c y kras g12d en el tratamiento del cancer.
|
EP4051678A1
(en)
|
2019-10-28 |
2022-09-07 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
US20230023023A1
(en)
|
2019-10-31 |
2023-01-26 |
Taiho Pharmaceutical Co., Ltd. |
4-aminobut-2-enamide derivatives and salts thereof
|
WO2021091967A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
AU2020379734A1
(en)
|
2019-11-04 |
2022-05-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
KR20220109407A
(ko)
|
2019-11-04 |
2022-08-04 |
레볼루션 메디슨즈, 인크. |
Ras 억제제
|
JP2023500328A
(ja)
|
2019-11-08 |
2023-01-05 |
レボリューション メディシンズ インコーポレイテッド |
二環式ヘテロアリール化合物及びその使用
|
CA3161156A1
(en)
|
2019-11-14 |
2021-05-20 |
Amgen Inc. |
Improved synthesis of kras g12c inhibitor compound
|
BR112022009390A2
(pt)
|
2019-11-14 |
2022-08-09 |
Amgen Inc |
Síntese melhorada de composto inibidor de kras g12c
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ras阻害剤及びその使用
|
WO2021106231A1
(en)
|
2019-11-29 |
2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
A compound having inhibitory activity against kras g12d mutation
|
MX2022006807A
(es)
|
2019-12-05 |
2022-09-12 |
Anakuria Therapeutics Inc |
Análogos de rapamicina y usos de estos.
|
TW202140011A
(zh)
|
2020-01-07 |
2021-11-01 |
美商銳新醫藥公司 |
Shp2抑制劑給藥和治療癌症的方法
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
WO2021215544A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
US20230255972A1
(en)
|
2020-07-15 |
2023-08-17 |
Taiho Pharmaceutical Co., Ltd. |
Pyrimidine compound-containing combination to be used in tumor treatment
|
IL301062A
(en)
|
2020-09-03 |
2023-05-01 |
Revolution Medicines Inc |
Use of SOS1 inhibitors to treat malignancies with SHP2 mutations
|
US11690915B2
(en)
|
2020-09-15 |
2023-07-04 |
Revolution Medicines, Inc. |
Ras inhibitors
|
CN117396472A
(zh)
|
2020-12-22 |
2024-01-12 |
上海齐鲁锐格医药研发有限公司 |
Sos1抑制剂及其用途
|
US11859021B2
(en)
|
2021-03-19 |
2024-01-02 |
Icahn School Of Medicine At Mount Sinai |
Compounds for regulating trained immunity, and their methods of use
|
JP2024517847A
(ja)
|
2021-05-05 |
2024-04-23 |
レボリューション メディシンズ インコーポレイテッド |
Ras阻害剤
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
CN117500811A
(zh)
|
2021-05-05 |
2024-02-02 |
锐新医药公司 |
共价ras抑制剂及其用途
|
EP4347041A1
(en)
|
2021-05-28 |
2024-04-10 |
Taiho Pharmaceutical Co., Ltd. |
Small molecule inhibitors of kras mutated proteins
|
CA3223081A1
(en)
|
2021-07-15 |
2023-01-19 |
Samir Mitragotri |
Compositions and methods relating to cells with adhered particles
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
WO2023114954A1
(en)
|
2021-12-17 |
2023-06-22 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|