GT198170557A - 9-amino-1-hidroxioctahidrobenzo (c) quinolinas y sus deriva-dos. - Google Patents

9-amino-1-hidroxioctahidrobenzo (c) quinolinas y sus deriva-dos.

Info

Publication number
GT198170557A
GT198170557A GT198170557A GT198170557A GT198170557A GT 198170557 A GT198170557 A GT 198170557A GT 198170557 A GT198170557 A GT 198170557A GT 198170557 A GT198170557 A GT 198170557A GT 198170557 A GT198170557 A GT 198170557A
Authority
GT
Guatemala
Prior art keywords
derivatives
hydroxioctahidrobenzo
quinolines
amino
refers
Prior art date
Application number
GT198170557A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT198170557A publication Critical patent/GT198170557A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

SE REFIERE A DERIVADOS DE 9AMINO1HIDROXIOCTAHIDROBENZO [C] QUINOLINA QUE TIENEN LA ESTRUCTURA QUIMICA I, CONTENIDA EN LA FICHA TECNICA RESPECTIVA. ESTOS COMPUESTOS SON UTILES COMO AGENTES DE TRATAMIENTO DEL SISTEMA NERVIOSO CENTRAL, ESPECIALMENTE COMO AGENTES ANALGESICOS Y ANTIEMETICOS PARA USOEN LOS MAMIFEROS, INCLUIDO EL HOMBRE. ESTA INVENCION SE RE FIERE TAMBIEN A METODOS PARA SU UTILIZACION Y A COMPOSICIO NES FARMACEUTICAS QUE LOS CONTIENEN.
GT198170557A 1980-07-28 1981-07-21 9-amino-1-hidroxioctahidrobenzo (c) quinolinas y sus deriva-dos. GT198170557A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (1)

Publication Number Publication Date
GT198170557A true GT198170557A (es) 1983-01-12

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
GT198170557A GT198170557A (es) 1980-07-28 1981-07-21 9-amino-1-hidroxioctahidrobenzo (c) quinolinas y sus deriva-dos.

Country Status (29)

Country Link
US (1) US4309545A (es)
EP (1) EP0045171B1 (es)
JP (1) JPS57112372A (es)
KR (1) KR850000273B1 (es)
AR (1) AR230988A1 (es)
AT (1) ATE11775T1 (es)
AU (1) AU525944B2 (es)
CA (1) CA1178274A (es)
CS (1) CS228515B2 (es)
DD (1) DD202012A5 (es)
DE (1) DE3168891D1 (es)
DK (1) DK334581A (es)
EG (1) EG15535A (es)
ES (1) ES8301926A1 (es)
FI (1) FI812338L (es)
GR (1) GR75283B (es)
GT (1) GT198170557A (es)
HU (1) HU185133B (es)
IE (1) IE51426B1 (es)
IL (1) IL63423A0 (es)
IN (1) IN158867B (es)
NO (2) NO812557L (es)
NZ (1) NZ197856A (es)
PH (1) PH17281A (es)
PL (1) PL133928B1 (es)
PT (1) PT73440B (es)
SU (1) SU1217254A3 (es)
YU (1) YU185181A (es)
ZA (1) ZA815128B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
EP0882021B1 (de) * 1996-01-31 2003-03-05 ALTANA Pharma AG Neue phenanthridine
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
EP0889886B1 (de) * 1996-03-26 2002-09-18 ALTANA Pharma AG Neue in 6-position substituierte phenanthridine
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
HUP0003311A3 (en) * 1997-07-25 2002-10-28 Altana Pharma Ag Substituted 6-phenylphenanthridine derivatives, pocess for producing them and pharmaceutical compositions containing them
EP1000034B1 (en) * 1997-07-25 2002-09-18 ALTANA Pharma AG Substituted 6-alkylphenanthridines
IL145470A0 (en) 1999-03-22 2002-06-30 Immugen Pharmaceuticals Inc Compositions for the treatment of immune diseases
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
US6541510B2 (en) * 2000-09-28 2003-04-01 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US20030232101A1 (en) * 2002-03-18 2003-12-18 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
EA012668B1 (ru) * 2004-05-25 2009-12-30 Отера Холдинг, Инк. Окулоселективные лекарственные средства и пролекарства

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
PH17281A (en) 1984-07-06
DE3168891D1 (en) 1985-03-28
IL63423A0 (en) 1981-10-30
PL232331A1 (en) 1983-09-26
PT73440A (en) 1981-08-01
AU525944B2 (en) 1982-12-09
NZ197856A (en) 1984-10-19
YU185181A (en) 1983-12-31
JPS57112372A (en) 1982-07-13
PL133928B1 (en) 1985-07-31
SU1217254A3 (ru) 1986-03-07
AR230988A1 (es) 1984-08-31
GR75283B (es) 1984-07-13
IE51426B1 (en) 1986-12-24
ES504323A0 (es) 1982-12-16
AU7343481A (en) 1982-05-06
IE811686L (en) 1982-01-28
HU185133B (en) 1984-12-28
EG15535A (en) 1986-09-30
KR830006217A (ko) 1983-09-20
IN158867B (es) 1987-02-07
EP0045171A2 (en) 1982-02-03
PT73440B (en) 1983-06-20
NO854454L (no) 1985-01-29
ES8301926A1 (es) 1982-12-16
US4309545A (en) 1982-01-05
CA1178274A (en) 1984-11-20
ZA815128B (en) 1982-07-28
FI812338L (fi) 1982-01-29
EP0045171A3 (en) 1982-04-28
KR850000273B1 (ko) 1985-03-15
EP0045171B1 (en) 1985-02-13
ATE11775T1 (de) 1985-02-15
NO812557L (no) 1982-01-29
DD202012A5 (de) 1983-08-24
CS228515B2 (en) 1984-05-14
DK334581A (da) 1982-01-29

Similar Documents

Publication Publication Date Title
GT198170557A (es) 9-amino-1-hidroxioctahidrobenzo (c) quinolinas y sus deriva-dos.
GT199200028A (es) Derivados de quinuclidina
GT199700079A (es) Derivados triciclos sustituidos con fenilamino
GT199700033A (es) Derivados de 6-fenilpiridil-2-amina.
ES2093979T3 (es) Esteres nitricos de derivados del acido 2-(2,6-dihalofenilamino)fenilacetico y su procedimiento de preparacion.
MX9301348A (es) Nuevos compuestos que tienen actividad farmacologica, proceso para su preparacion y composicion farmaceutica que los comprende.
UY24799A1 (es) Derivados de 6-fenilpiridil-2-amina
GT199800032A (es) 2-amino-6-(4-fenoxi-2-sustituido)-piridinas sustituidas.
GT199800205A (es) Compuestos de indol 2,3-sustituidos como agentes anti-inflamatorios y analgesicos.
PA8457001A1 (es) Derivados del 2-(4-aril o heteroaril-piperazin-i-ilmetil)-1h-indol
DE3677868D1 (de) Verfahren zur fluoreszenzloeschung und neue kationische naphthalin-peri-dicarbonsaeureimid-derivate.
ES2076595T3 (es) Derivados de amidinofenilalanina, procedimiento para su preparacion, su empleo y agentes que los contienen.
ES2170798T3 (es) Benzopiranos y su uso como agentes terapeuticos.
GT197226400A (es) Procedimiento para la preparacion de nuevas benzodiazepinas.
ES2173435T3 (es) Derivados condensados de 2,3-benzodiazepinas y su utilizacion como agentes inhibidores de receptores de ampa.
GT197225694A (es) Agentes para el control de organismos patogenos de las plantas.
GT200100021A (es) Nuevos derivados de amidas heterociclicas.
ES2055440T3 (es) Derivados del acido quinurenico, su preparacion y composiciones farmaceuticas que los contienen.
ES2058269T3 (es) Di-t-butilfenil-alquil y -bencil-eteres.
FR2389624A1 (es)
ES2061531T3 (es) Derivados de azepinona y azocinona condensados, procedimientos para su preparacion, agentes que los contienen y su utilizacion, asi como productos intermedios en su preparacion.
GT197957904A (es) Nuevos derivados de 4-amino-2-piperidinoquinazolina.
ES2183843T3 (es) Compuestos triciclicos que tienen afinidad por el receptor 5-ht1a.
GT198170267A (es) N(1-alil-2-pirrolidinil-metil)-2-metoxi-4-amino-5-metilsulfamoil-benzamida, su procedimiento de preparacion y su aplicacion como medicamento.
ECSP972152A (es) Compuestos que tienen actividad farmacologica, procedimientos para su preparacion, composiciones que los contienen y su uso en el tratamiento del sistema nervioso central