PT73440B - Process for preparing 9-amino-1-hydroxyoctahydrobenzo<c> quinolines and derivatives thereof - Google Patents

Process for preparing 9-amino-1-hydroxyoctahydrobenzo<c> quinolines and derivatives thereof

Info

Publication number
PT73440B
PT73440B PT73440A PT7344081A PT73440B PT 73440 B PT73440 B PT 73440B PT 73440 A PT73440 A PT 73440A PT 7344081 A PT7344081 A PT 7344081A PT 73440 B PT73440 B PT 73440B
Authority
PT
Portugal
Prior art keywords
hydroxyoctahydrobenzo
quinolines
derivatives
amino
preparing
Prior art date
Application number
PT73440A
Other languages
English (en)
Other versions
PT73440A (en
Inventor
Michael Ross Johnson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT73440A publication Critical patent/PT73440A/pt
Publication of PT73440B publication Critical patent/PT73440B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/10Aza-phenanthrenes
    • C07D221/12Phenanthridines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT73440A 1980-07-28 1981-07-28 Process for preparing 9-amino-1-hydroxyoctahydrobenzo<c> quinolines and derivatives thereof PT73440B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof

Publications (2)

Publication Number Publication Date
PT73440A PT73440A (en) 1981-08-01
PT73440B true PT73440B (en) 1983-06-20

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
PT73440A PT73440B (en) 1980-07-28 1981-07-28 Process for preparing 9-amino-1-hydroxyoctahydrobenzo<c> quinolines and derivatives thereof

Country Status (29)

Country Link
US (1) US4309545A (pt)
EP (1) EP0045171B1 (pt)
JP (1) JPS57112372A (pt)
KR (1) KR850000273B1 (pt)
AR (1) AR230988A1 (pt)
AT (1) ATE11775T1 (pt)
AU (1) AU525944B2 (pt)
CA (1) CA1178274A (pt)
CS (1) CS228515B2 (pt)
DD (1) DD202012A5 (pt)
DE (1) DE3168891D1 (pt)
DK (1) DK334581A (pt)
EG (1) EG15535A (pt)
ES (1) ES8301926A1 (pt)
FI (1) FI812338L (pt)
GR (1) GR75283B (pt)
GT (1) GT198170557A (pt)
HU (1) HU185133B (pt)
IE (1) IE51426B1 (pt)
IL (1) IL63423A0 (pt)
IN (1) IN158867B (pt)
NO (2) NO812557L (pt)
NZ (1) NZ197856A (pt)
PH (1) PH17281A (pt)
PL (1) PL133928B1 (pt)
PT (1) PT73440B (pt)
SU (1) SU1217254A3 (pt)
YU (1) YU185181A (pt)
ZA (1) ZA815128B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
EP0882021B1 (de) * 1996-01-31 2003-03-05 ALTANA Pharma AG Neue phenanthridine
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
EP0889886B1 (de) * 1996-03-26 2002-09-18 ALTANA Pharma AG Neue in 6-position substituierte phenanthridine
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
HUP0003311A3 (en) * 1997-07-25 2002-10-28 Altana Pharma Ag Substituted 6-phenylphenanthridine derivatives, pocess for producing them and pharmaceutical compositions containing them
EP1000034B1 (en) * 1997-07-25 2002-09-18 ALTANA Pharma AG Substituted 6-alkylphenanthridines
IL145470A0 (en) 1999-03-22 2002-06-30 Immugen Pharmaceuticals Inc Compositions for the treatment of immune diseases
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
US6541510B2 (en) * 2000-09-28 2003-04-01 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US20030232101A1 (en) * 2002-03-18 2003-12-18 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
EA012668B1 (ru) * 2004-05-25 2009-12-30 Отера Холдинг, Инк. Окулоселективные лекарственные средства и пролекарства

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
PH17281A (en) 1984-07-06
DE3168891D1 (en) 1985-03-28
IL63423A0 (en) 1981-10-30
PL232331A1 (en) 1983-09-26
PT73440A (en) 1981-08-01
AU525944B2 (en) 1982-12-09
NZ197856A (en) 1984-10-19
YU185181A (en) 1983-12-31
JPS57112372A (en) 1982-07-13
PL133928B1 (en) 1985-07-31
SU1217254A3 (ru) 1986-03-07
AR230988A1 (es) 1984-08-31
GT198170557A (es) 1983-01-12
GR75283B (pt) 1984-07-13
IE51426B1 (en) 1986-12-24
ES504323A0 (es) 1982-12-16
AU7343481A (en) 1982-05-06
IE811686L (en) 1982-01-28
HU185133B (en) 1984-12-28
EG15535A (en) 1986-09-30
KR830006217A (ko) 1983-09-20
IN158867B (pt) 1987-02-07
EP0045171A2 (en) 1982-02-03
NO854454L (no) 1985-01-29
ES8301926A1 (es) 1982-12-16
US4309545A (en) 1982-01-05
CA1178274A (en) 1984-11-20
ZA815128B (en) 1982-07-28
FI812338L (fi) 1982-01-29
EP0045171A3 (en) 1982-04-28
KR850000273B1 (ko) 1985-03-15
EP0045171B1 (en) 1985-02-13
ATE11775T1 (de) 1985-02-15
NO812557L (no) 1982-01-29
DD202012A5 (de) 1983-08-24
CS228515B2 (en) 1984-05-14
DK334581A (da) 1982-01-29

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Legal Events

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19941231