GR871576B - Antitumor anthracycline glycosides their preparation intermediates thereof and compositions and use thereof - Google Patents

Antitumor anthracycline glycosides their preparation intermediates thereof and compositions and use thereof

Info

Publication number: GR871576B
Authority: GR; Greece
Prior art keywords: compositions; anthracycline glycosides; preparation intermediates; antitumor anthracycline; antitumor
Prior art date: 1986-10-15

Application number

GR871576A

Other languages

English (en)

Inventor

Bargiotti Alberto

Bordoni Teresa

Zini Pierangelo

Penco Sergio

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-10-15

Filing date

1987-10-13

Publication date

1988-02-17

1987-10-13 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1988-02-17 Publication of GR871576B publication Critical patent/GR871576B/el

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Crystallography & Structural Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

GR871576A 1986-10-15 1987-10-13 Antitumor anthracycline glycosides their preparation intermediates thereof and compositions and use thereof GR871576B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8624687A GB2196626B (en)	1986-10-15	1986-10-15	Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor

Publications (1)

Publication Number	Publication Date
GR871576B true GR871576B (en)	1988-02-17

Family

ID=10605771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR871576A GR871576B (en)	1986-10-15	1987-10-13	Antitumor anthracycline glycosides their preparation intermediates thereof and compositions and use thereof

Country Status (21)

Country	Link
US (1)	US4839346A (el)
JP (1)	JPS63258485A (el)
AU (1)	AU7955087A (el)
BE (1)	BE1000407A4 (el)
CA (1)	CA1289950C (el)
DE (1)	DE3734476A1 (el)
DK (1)	DK533087A (el)
ES (1)	ES2007419A6 (el)
FI (1)	FI874470A (el)
FR (1)	FR2605321B1 (el)
GB (1)	GB2196626B (el)
GR (1)	GR871576B (el)
HU (1)	HU198505B (el)
IL (1)	IL84146A0 (el)
IT (1)	IT1226375B (el)
MY (1)	MY102186A (el)
NL (1)	NL8702436A (el)
NZ (1)	NZ222113A (el)
PT (1)	PT85916A (el)
SE (1)	SE8703999L (el)
ZA (1)	ZA877681B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8708927D0 (en) *	1987-04-14	1987-05-20	Erba Farmitalia	Chiral synthesis of anthracyclines
FR2636949A1 (fr) *	1988-09-28	1990-03-30	Hoechst Sa Laboratoires	Nouveaux analogues de la desoxy-4 daunosamine, procede de preparation, anthracyclines obtenues a l'aide de ces analogues et utilisation desdites anthracyclines en tant que medicaments
GB9019934D0 (en) *	1990-09-12	1990-10-24	Erba Carlo Spa	2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9028105D0 (en) *	1990-12-27	1991-02-13	Erba Carlo Spa	Process for the preparation of substituted benzofuran derivatives
GB9216962D0 (en) *	1992-08-11	1992-09-23	Erba Carlo Spa	Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
US5948896A (en) *	1997-08-13	1999-09-07	Gem Pharmaceuticals	Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) *	1998-03-03	1999-08-24	Gem Pharmaceuticals, Inc.	5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
US6235782B1 (en)	1998-11-12	2001-05-22	Rifat Pamukcu	Method for treating a patient with neoplasia by treatment with a platinum coordination complex
US6235776B1 (en)	1998-11-12	2001-05-22	Cell Pathways, Inc.	Method for treating a patient with neoplasia by treatment with a paclitaxel derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates
GB1506200A (en) *	1975-04-30	1978-04-05	Farmaceutici Italia	Glycosides
US4254110A (en) *	1979-02-02	1981-03-03	Farmitalia Carlo Erba S.P.A.	Pentofuranosyl anthracyclines, intermediates in and method for their preparation and compositions and use thereof
US4275192A (en) *	1979-05-03	1981-06-23	G. D. Searle & Co.	Bis(4-demethoxydaunorubicin)dihydrazone derivatives and pharmacologically acceptable salts thereof
US4345068A (en) *	1979-11-22	1982-08-17	Farmitalia Carlo Erba S.P.A.	Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process
US4563444A (en) *	1982-05-26	1986-01-07	Farmitalia Carlo Erba S.P.A.	Anthracycline glycosides, use and compositions containing same
US4562177A (en) *	1982-08-17	1985-12-31	The Ohio State University Research Foundation	3'-Amino-2' halo-anthracycline antibiotics

1986
- 1986-10-15 GB GB8624687A patent/GB2196626B/en not_active Expired - Fee Related
1987
- 1987-09-28 US US07/101,382 patent/US4839346A/en not_active Expired - Fee Related
- 1987-10-01 MY MYPI87002762A patent/MY102186A/en unknown
- 1987-10-09 NZ NZ222113A patent/NZ222113A/xx unknown
- 1987-10-09 IT IT8722202A patent/IT1226375B/it active
- 1987-10-12 FI FI874470A patent/FI874470A/fi not_active Application Discontinuation
- 1987-10-12 DK DK533087A patent/DK533087A/da not_active Application Discontinuation
- 1987-10-12 AU AU79550/87A patent/AU7955087A/en not_active Abandoned
- 1987-10-12 DE DE19873734476 patent/DE3734476A1/de not_active Ceased
- 1987-10-12 IL IL84146A patent/IL84146A0/xx unknown
- 1987-10-12 FR FR878714058A patent/FR2605321B1/fr not_active Expired
- 1987-10-13 CA CA000549085A patent/CA1289950C/en not_active Expired - Fee Related
- 1987-10-13 ES ES8702918A patent/ES2007419A6/es not_active Expired
- 1987-10-13 PT PT85916A patent/PT85916A/pt not_active Application Discontinuation
- 1987-10-13 NL NL8702436A patent/NL8702436A/nl not_active Application Discontinuation
- 1987-10-13 GR GR871576A patent/GR871576B/el unknown
- 1987-10-13 ZA ZA877681A patent/ZA877681B/xx unknown
- 1987-10-13 BE BE8701170A patent/BE1000407A4/fr not_active IP Right Cessation
- 1987-10-14 HU HU874643A patent/HU198505B/hu not_active IP Right Cessation
- 1987-10-14 JP JP62259441A patent/JPS63258485A/ja active Pending
- 1987-10-14 SE SE8703999A patent/SE8703999L/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK533087D0 (da)	1987-10-12
AU7955087A (en)	1988-04-21
DK533087A (da)	1988-04-16
PT85916A (pt)	1988-11-30
HUT46030A (en)	1988-09-28
NL8702436A (nl)	1988-05-02
IL84146A0 (en)	1988-03-31
US4839346A (en)	1989-06-13
FR2605321A1 (fr)	1988-04-22
FI874470A0 (fi)	1987-10-12
SE8703999L (sv)	1988-04-16
MY102186A (en)	1992-04-30
GB2196626B (en)	1990-09-19
ES2007419A6 (es)	1989-06-16
BE1000407A4 (fr)	1988-11-22
SE8703999D0 (sv)	1987-10-14
HU198505B (en)	1989-10-30
IT1226375B (it)	1991-01-11
CA1289950C (en)	1991-10-01
GB2196626A (en)	1988-05-05
FR2605321B1 (fr)	1989-07-07
NZ222113A (en)	1989-11-28
ZA877681B (en)	1988-06-29
DE3734476A1 (de)	1988-04-21
IT8722202A0 (it)	1987-10-09
GB8624687D0 (en)	1986-11-19
JPS63258485A (ja)	1988-10-25
FI874470A (fi)	1988-04-16

Publication	Publication Date	Title
IL76732A0 (en)	1986-02-28	Pharmaceutical compositions containing anthracycline glycosides and their preparation
DE3268367D1 (en)	1986-02-20	Anthracycline glycoside compositions, their use and preparation
IL86412A0 (en)	1988-11-15	Doxorubicin/liposome compositions and their preparation
IL79129A (en)	1992-03-29	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside and their preparation
NZ192758A (en)	1982-03-09	Anthracycline glycosides and pharmaceutical compositions
GR871576B (en)	1988-02-17	Antitumor anthracycline glycosides their preparation intermediates thereof and compositions and use thereof
IL82820A0 (en)	1987-12-20	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
IL72168A0 (en)	1984-10-31	Preparation of 6-deoxy-anthracyclines,anthracycline glycosides prepared therefrom and their preparation
NZ218256A (en)	1988-11-29	Anthracycline glycosides and pharmaceutical compositions
IL68720A0 (en)	1983-09-30	Anthracycline glycosides and their preparation
IL63287A (en)	1984-10-31	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
GB2191479B (en)	1989-12-28	New antitumor anthracycline glycosides
JPS6485991A (en)	1989-03-30	Novel sulfono analogue and sulfoxo analogue of daunomycin and adriamycin
IE872719L (en)	1988-04-15	Anthracycline glycosides and related intermediates
IE862977L (en)	1987-05-19	Anthracycline glycosides
GB2218087B (en)	1991-01-30	4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides
IL104975A0 (en)	1993-07-08	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
IL104974A0 (en)	1993-07-08	Anthracycline glycosides,their preparation and pharmaceutical compositions containing them
IE851662L (en)	1986-01-03	Anthracycline glycosides
GB8520835D0 (en)	1985-09-25	Anthracycline glycosides
MY8400399A (en)	1984-12-31	Anthracycline glycosides
GB8928654D0 (en)	1990-02-21	Preparation of 2-methoxy-4-morpholinyl anthracyclines
IL100329A (en)	1992-11-15	4-demethoxy-4-amino daunorubicin and its preparation
IE883354L (en)	1989-05-10	Anthracycline glycosides
IL85796A0 (en)	1988-09-30	Novel anthracycline glycosides,process for their preparation and cytostatic compositions containing same