GB2218087B - 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides - Google Patents

4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides

Info

Publication number
GB2218087B
GB2218087B GB8809615A GB8809615A GB2218087B GB 2218087 B GB2218087 B GB 2218087B GB 8809615 A GB8809615 A GB 8809615A GB 8809615 A GB8809615 A GB 8809615A GB 2218087 B GB2218087 B GB 2218087B
Authority
GB
United Kingdom
Prior art keywords
demethoxy
deoxy
iodo
anthracycline glycosides
anthracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8809615A
Other versions
GB2218087A (en
GB8809615D0 (en
Inventor
Antonino Suarato
Michele Caruso
Sergio Penco
Fernando Giuliani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Priority to GB8809615A priority Critical patent/GB2218087B/en
Publication of GB8809615D0 publication Critical patent/GB8809615D0/en
Priority to DE3912867A priority patent/DE3912867A1/en
Priority to IT8920197A priority patent/IT1230065B/en
Priority to JP1101521A priority patent/JPH01311095A/en
Publication of GB2218087A publication Critical patent/GB2218087A/en
Application granted granted Critical
Publication of GB2218087B publication Critical patent/GB2218087B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
GB8809615A 1988-04-22 1988-04-22 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides Expired - Fee Related GB2218087B (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB8809615A GB2218087B (en) 1988-04-22 1988-04-22 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides
DE3912867A DE3912867A1 (en) 1988-04-22 1989-04-19 4-DESMETHOXY-4'-DESOXY-4'-JODOANTHRACYCLINGLYCOSIDE AND METHOD FOR THE PRODUCTION THEREOF
IT8920197A IT1230065B (en) 1988-04-22 1989-04-19 4-DEMETOSSI-4'-DESOSSI-4'-IODO GLYCOSIDES OF ANTHRACYCLINE
JP1101521A JPH01311095A (en) 1988-04-22 1989-04-20 4-demethoxy-4'-deoxy-4'-iodoanthracycline glycoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8809615A GB2218087B (en) 1988-04-22 1988-04-22 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides

Publications (3)

Publication Number Publication Date
GB8809615D0 GB8809615D0 (en) 1988-05-25
GB2218087A GB2218087A (en) 1989-11-08
GB2218087B true GB2218087B (en) 1991-01-30

Family

ID=10635701

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8809615A Expired - Fee Related GB2218087B (en) 1988-04-22 1988-04-22 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides

Country Status (4)

Country Link
JP (1) JPH01311095A (en)
DE (1) DE3912867A1 (en)
GB (1) GB2218087B (en)
IT (1) IT1230065B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2118540A (en) * 1982-04-19 1983-11-02 Erba Farmitalia Anthracycline glycosides
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
GB8321676D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia 4'-haloanthrocycline glycosides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2118540A (en) * 1982-04-19 1983-11-02 Erba Farmitalia Anthracycline glycosides
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dictionary of Antibiotics and Related Substances, ed B W Bycroft (Chapman & Hall, 1988) pp16 and 402 *

Also Published As

Publication number Publication date
DE3912867A1 (en) 1989-11-02
JPH01311095A (en) 1989-12-15
GB2218087A (en) 1989-11-08
IT8920197A0 (en) 1989-04-19
GB8809615D0 (en) 1988-05-25
IT1230065B (en) 1991-09-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19970422