GB836325A - New camphidine derivatives and processes for their preparation - Google Patents

New camphidine derivatives and processes for their preparation

Info

Publication number
GB836325A
GB836325A GB17885/58A GB1788558A GB836325A GB 836325 A GB836325 A GB 836325A GB 17885/58 A GB17885/58 A GB 17885/58A GB 1788558 A GB1788558 A GB 1788558A GB 836325 A GB836325 A GB 836325A
Authority
GB
United Kingdom
Prior art keywords
alkyl
preparation
chlorocamphoric
dialkylamino
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB17885/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia AS
Original Assignee
Pharmacia AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AS filed Critical Pharmacia AS
Publication of GB836325A publication Critical patent/GB836325A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/24—Camphidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:0836325/IV (b)/1> in which R represents an alkyl or dialkylamino-alkyl group where each alkyl group preferably has 1-4 carbon atoms; and acid addition salts and mono- and bis-quaternary ammonium salts thereof; and the preparation thereof by reducing corresponding N-substituted 5-chlorocamphoric acid imides, e.g. with a hydride, particularly lithium aluminium hydride; and, if desired, treating the products with alkylating agents of the general formula Alk-X, in which Alk represents one or two alkyl groups each preferably having not more than 4 carbon atoms and X represents an anion. N - substituted 5 - chloro - camphoric acid imides are prepared by treating 5-chlorocamphoric acid imide with an alkyl halide or a dialkylamino-alkyl halide hydrohalide in alcoholic alkali metal p hydroxide solution.
GB17885/58A 1957-06-05 1958-06-04 New camphidine derivatives and processes for their preparation Expired GB836325A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE836325X 1957-06-05

Publications (1)

Publication Number Publication Date
GB836325A true GB836325A (en) 1960-06-01

Family

ID=6761139

Family Applications (1)

Application Number Title Priority Date Filing Date
GB17885/58A Expired GB836325A (en) 1957-06-05 1958-06-04 New camphidine derivatives and processes for their preparation

Country Status (1)

Country Link
GB (1) GB836325A (en)

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