GB1294159A - Derivatives of 1-amino-3-phenoxy-propan-2-ol, and processes for preparing them - Google Patents
Derivatives of 1-amino-3-phenoxy-propan-2-ol, and processes for preparing themInfo
- Publication number
- GB1294159A GB1294159A GB51695/70A GB5169570A GB1294159A GB 1294159 A GB1294159 A GB 1294159A GB 51695/70 A GB51695/70 A GB 51695/70A GB 5169570 A GB5169570 A GB 5169570A GB 1294159 A GB1294159 A GB 1294159A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- prepared
- propan
- phenoxy
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1294159 Propanolamine derivatives ROUSSEL UCLAF 30 Oct 1970 [3 Nov 1969] 51695/70 Heading C2C Compounds of the general formula (Ar=o- or p-cyclopropylphenyl, R<SP>1,2</SP>=H, alkyl containing up to 5 carbon atoms or C 3-7 cycloalkyl, at least one of R<SP>1,2</SP> not being H) and their acid addition and quaternary ammonium salts are prepared by reacting 1-(o- or p-cyclopropylphenoxy) - 2,3 - epoxypropane with R<SP>1</SP>R<SP>2</SP>NH, optionally followed by salt formation. The starting materials are prepared by reacting ArOH with epichlorohydrin in the presence of a base. The above compounds are #-adrenergic blocking agents, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR6937692A FR2068422A1 (en) | 1969-11-03 | 1969-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1294159A true GB1294159A (en) | 1972-10-25 |
Family
ID=9042491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB51695/70A Expired GB1294159A (en) | 1969-11-03 | 1970-10-30 | Derivatives of 1-amino-3-phenoxy-propan-2-ol, and processes for preparing them |
Country Status (11)
| Country | Link |
|---|---|
| BE (1) | BE758303A (en) |
| CA (1) | CA943139A (en) |
| CH (1) | CH533594A (en) |
| DE (1) | DE2053192C3 (en) |
| DK (1) | DK127878B (en) |
| ES (1) | ES385062A1 (en) |
| FR (1) | FR2068422A1 (en) |
| GB (1) | GB1294159A (en) |
| IL (1) | IL35378A (en) |
| NL (1) | NL7015922A (en) |
| SE (1) | SE370392B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2361106A2 (en) * | 1976-08-10 | 1978-03-10 | Mar Pha Etu Et Expl De Marques | NEW TERPENO-PHENOXY-ALKYLAMINES |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1668055B2 (en) * | 1967-03-10 | 1973-09-06 | Farbwerke Hoechst AG, vormals Mei ster Lucius & Bruning, 6000 Frankfurt | BASIC SUBSTITUTED CYCLOPENTYLPHENOLETHERS, THEIR SALT WITH PHYSIOLOGICALLY COMPATIBLE ACIDS AND PROCESS FOR THEIR PRODUCTION |
-
0
- BE BE758303D patent/BE758303A/en unknown
-
1969
- 1969-11-03 FR FR6937692A patent/FR2068422A1/fr not_active Withdrawn
-
1970
- 1970-09-30 IL IL35378A patent/IL35378A/en unknown
- 1970-10-29 DE DE2053192A patent/DE2053192C3/en not_active Expired
- 1970-10-30 GB GB51695/70A patent/GB1294159A/en not_active Expired
- 1970-10-30 NL NL7015922A patent/NL7015922A/xx not_active Application Discontinuation
- 1970-10-30 ES ES385062A patent/ES385062A1/en not_active Expired
- 1970-11-02 CH CH1621970A patent/CH533594A/en not_active IP Right Cessation
- 1970-11-02 CA CA097,196*7A patent/CA943139A/en not_active Expired
- 1970-11-02 DK DK555070AA patent/DK127878B/en unknown
- 1970-11-03 SE SE7014860A patent/SE370392B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA943139A (en) | 1974-03-05 |
| IL35378A (en) | 1973-11-28 |
| NL7015922A (en) | 1971-05-05 |
| DE2053192B2 (en) | 1973-07-12 |
| DK127878B (en) | 1974-01-28 |
| FR2068422A1 (en) | 1971-08-27 |
| IL35378A0 (en) | 1970-11-30 |
| DE2053192A1 (en) | 1971-07-01 |
| BE758303A (en) | 1971-04-30 |
| SE370392B (en) | 1974-10-14 |
| DE2053192C3 (en) | 1974-02-28 |
| ES385062A1 (en) | 1973-03-16 |
| CH533594A (en) | 1973-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |