GB2155478B - 1a-hydroxyvitamin d2 analogs and process for preparing same - Google Patents

1a-hydroxyvitamin d2 analogs and process for preparing same

Info

Publication number
GB2155478B
GB2155478B GB08505486A GB8505486A GB2155478B GB 2155478 B GB2155478 B GB 2155478B GB 08505486 A GB08505486 A GB 08505486A GB 8505486 A GB8505486 A GB 8505486A GB 2155478 B GB2155478 B GB 2155478B
Authority
GB
United Kingdom
Prior art keywords
hydroxyvitamin
analogs
preparing same
preparing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08505486A
Other versions
GB2155478A (en
GB8505486D0 (en
Inventor
Luca Hector F De
Heinrich K Schnoes
Rafal R Sicinski
Yoko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of GB8505486D0 publication Critical patent/GB8505486D0/en
Publication of GB2155478A publication Critical patent/GB2155478A/en
Application granted granted Critical
Publication of GB2155478B publication Critical patent/GB2155478B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB08505486A 1984-03-05 1985-03-04 1a-hydroxyvitamin d2 analogs and process for preparing same Expired GB2155478B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58616084A 1984-03-05 1984-03-05

Publications (3)

Publication Number Publication Date
GB8505486D0 GB8505486D0 (en) 1985-04-03
GB2155478A GB2155478A (en) 1985-09-25
GB2155478B true GB2155478B (en) 1987-12-16

Family

ID=24344548

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08505486A Expired GB2155478B (en) 1984-03-05 1985-03-04 1a-hydroxyvitamin d2 analogs and process for preparing same

Country Status (12)

Country Link
JP (1) JPH064536B2 (en)
AU (1) AU584071B2 (en)
BE (1) BE901879A (en)
CH (1) CH667658A5 (en)
DE (2) DE3590080C2 (en)
DK (1) DK153145C (en)
FR (1) FR2560597B1 (en)
GB (1) GB2155478B (en)
IE (1) IE57951B1 (en)
IL (1) IL74168A (en)
NL (1) NL8520021A (en)
WO (1) WO1985003939A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
IN171426B (en) * 1990-02-14 1992-10-10 Wisconsin Alumni Res Found

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US4195027A (en) * 1978-01-16 1980-03-25 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
US4206131A (en) * 1978-06-19 1980-06-03 The Upjohn Company Compounds and process
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
DE3590021C2 (en) * 1984-01-30 1992-09-10 Wisconsin Alumni Res Found Alpha-hydroxyvitamin D derivative and medicinal product containing the same

Also Published As

Publication number Publication date
IL74168A (en) 1988-11-15
CH667658A5 (en) 1988-10-31
FR2560597B1 (en) 1987-12-04
DK153145C (en) 1988-10-31
JPH064536B2 (en) 1994-01-19
DE3590080T (en) 1986-02-20
NL8520021A (en) 1986-02-03
AU3889585A (en) 1985-09-24
WO1985003939A1 (en) 1985-09-12
DK506985A (en) 1985-11-06
BE901879A (en) 1985-07-01
DK153145B (en) 1988-06-20
IE57951B1 (en) 1993-05-19
FR2560597A1 (en) 1985-09-06
IE850520L (en) 1985-09-05
JPS61501447A (en) 1986-07-17
AU584071B2 (en) 1989-05-18
GB2155478A (en) 1985-09-25
DE3590080C2 (en) 1992-08-06
IL74168A0 (en) 1985-04-30
GB8505486D0 (en) 1985-04-03
DK506985D0 (en) 1985-11-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19990304