GB1331568A - Process for obtaining a differential white blood cell count - Google Patents
Process for obtaining a differential white blood cell countInfo
- Publication number
- GB1331568A GB1331568A GB4971771A GB4971771A GB1331568A GB 1331568 A GB1331568 A GB 1331568A GB 4971771 A GB4971771 A GB 4971771A GB 4971771 A GB4971771 A GB 4971771A GB 1331568 A GB1331568 A GB 1331568A
- Authority
- GB
- United Kingdom
- Prior art keywords
- white blood
- cell
- cells
- detecting
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000265 leukocyte Anatomy 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 238000004820 blood count Methods 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 5
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 230000003197 catalytic effect Effects 0.000 abstract 2
- LVSPDZAGCBEQAV-UHFFFAOYSA-N 4-chloronaphthalen-1-ol Chemical compound C1=CC=C2C(O)=CC=C(Cl)C2=C1 LVSPDZAGCBEQAV-UHFFFAOYSA-N 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000093 cytochemical effect Effects 0.000 abstract 1
- 230000002380 cytological effect Effects 0.000 abstract 1
- 210000003979 eosinophil Anatomy 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 210000001616 monocyte Anatomy 0.000 abstract 1
- -1 naphthyl ester Chemical class 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N2001/305—Fixative compositions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Ecology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8533370A | 1970-10-30 | 1970-10-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1331568A true GB1331568A (en) | 1973-09-26 |
Family
ID=22190904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4971771A Expired GB1331568A (en) | 1970-10-30 | 1971-10-26 | Process for obtaining a differential white blood cell count |
Country Status (12)
Country | Link |
---|---|
US (1) | US3741875A (ru) |
JP (2) | JPS576932B1 (ru) |
AU (1) | AU460469B2 (ru) |
BE (1) | BE774311A (ru) |
CA (1) | CA960947A (ru) |
DE (1) | DE2153479B2 (ru) |
FR (1) | FR2113336A5 (ru) |
GB (1) | GB1331568A (ru) |
IT (1) | IT961518B (ru) |
NL (1) | NL172463C (ru) |
SE (1) | SE372417B (ru) |
SU (1) | SU611598A3 (ru) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4581223A (en) * | 1980-03-12 | 1986-04-08 | Lawrence Kass | Individual leukocyte determination by means of differential metachromatic dye sorption |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2125699B2 (de) * | 1971-05-25 | 1973-05-17 | Phywe AG, 3400 Gottingen | Praeparation von zellen zur messung von dns |
US4049381A (en) * | 1976-03-23 | 1977-09-20 | Technicon Instruments Corporation | Apparatus and method of fluid sample analysis |
US4099917A (en) * | 1977-07-21 | 1978-07-11 | Technicon Instruments Corporation | Process for preparing a cell suspension from blood for discrimination of white blood cells and platelets from other blood particles |
DE2826965A1 (de) * | 1978-06-20 | 1980-01-17 | Boehringer Mannheim Gmbh | Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten und dafuer geeignete chromogene |
US4492752A (en) * | 1982-09-03 | 1985-01-08 | Ortho Diagnostics Systems Inc. | Method for discriminating between unstained and absorbing dye stained cells |
CA1254134A (en) * | 1984-03-28 | 1989-05-16 | Mount Sinai School Of Medicine Of The City University Of New York | Specific binding flow cytometry method |
US4654312A (en) * | 1984-05-14 | 1987-03-31 | Becton, Dickinson And Company | Lysing agent for analysis of peripheral blood cells |
US4751179A (en) * | 1984-05-31 | 1988-06-14 | Coulter Electronics, Inc. | Method and reagents for differential determination of four populations of leukocytes in blood |
US4978624A (en) * | 1985-09-06 | 1990-12-18 | Technicon Instruments Corporation | Reagent for the determination of a differential white blood cell count |
AU602129B2 (en) * | 1985-09-06 | 1990-10-04 | Technicon Instruments Corportion | Method for the determination of a differential white blood cell count |
US4801549A (en) * | 1985-09-06 | 1989-01-31 | Technicon Instruments Corporation | Method for the determination of a differential white blood cell count |
US5389549A (en) * | 1987-05-29 | 1995-02-14 | Toa Medical Electronics Co., Ltd. | Method for classifying leukocytes and a reagent used therefor |
WO1989007880A2 (en) * | 1988-02-10 | 1989-09-08 | Nygene Corporation | Process for producing biochemicals |
US5316725A (en) * | 1991-06-07 | 1994-05-31 | Edward Lawrence Carver, Jr. | Reagent system for the improved determination of white blood cell subpopulations |
US5262329A (en) * | 1991-06-13 | 1993-11-16 | Carver Jr Edward L | Method for improved multiple species blood analysis |
US6046019A (en) * | 1991-07-09 | 2000-04-04 | Goumeniouk; Alexander P. | Diagnostic kits and methods for making granulocyte cell counts |
CA2129834A1 (en) * | 1992-02-24 | 1993-08-25 | Michael N. Elliott | Suspension media for hematological composition and method for its use |
US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
US6362003B1 (en) | 1992-02-24 | 2002-03-26 | Coulter Corporation | Hematological reference control composition containing leukocyte analogs, methods of making, and uses thereof |
EP0628167B1 (en) * | 1992-02-24 | 2000-08-23 | Coulter Corporation | Hematology control composition for leukocyte analogs; and methods for their preparation and use |
US6812032B1 (en) * | 1993-01-21 | 2004-11-02 | Cdc Technologies, Inc. | Apparatus and method for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
US5599501A (en) * | 1994-11-10 | 1997-02-04 | Ciba Corning Diagnostics Corp. | Incubation chamber |
WO1996034283A1 (en) * | 1995-04-27 | 1996-10-31 | Hematronix, Inc. | Lytic system utilizing propionic acid for leukocytes differentiation |
US5639630A (en) * | 1995-05-16 | 1997-06-17 | Bayer Corporation | Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes |
US5843608A (en) * | 1995-06-08 | 1998-12-01 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
US5686308A (en) * | 1995-06-08 | 1997-11-11 | Coulter Corporation | Reagent and method for differential determination of leukocytes in blood |
US6146901A (en) * | 1997-06-16 | 2000-11-14 | Hematronix, Inc. | Composition for manipulating optical and electrical properties of particles to achieve target values for such properties and methods for using the composition |
US6759246B1 (en) | 2001-11-30 | 2004-07-06 | Research & Diagnostic Systems, Inc. | Hematology control composition including lymphocyte analogs and method for preparation and use |
CA2428740A1 (en) * | 2002-05-20 | 2003-11-20 | Bayer Corporation | Automated method and reagent therefor for assaying body fluid samples such as cerebrospinal fluid (csf) |
EP2525222A1 (en) | 2011-05-17 | 2012-11-21 | Markus M. Heiss | Initial relative lymphocyte count as predictive biomarker |
EP3519597B1 (en) | 2016-09-27 | 2021-01-27 | Novelis, Inc. | Magnetic levitation heating of metal with controlled surface quality |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2807416A (en) * | 1953-07-13 | 1957-09-24 | Ohio Commw Eng Co | Device for automatically counting blood cells |
DE1200577B (de) * | 1962-05-29 | 1965-09-09 | Habil Hans Meyer Doering Dr Me | Anordnung zum Zaehlen der in einem stroemungs-faehigen und lichtdurchlaessigen Medium mitgefuehrten, die Helligkeit eines auf sie gerichteten Lichtstrahles beeinflussenden Teilchen |
US3413464A (en) * | 1965-04-29 | 1968-11-26 | Ibm | Method for measuring the nucleic acid in biological cells after enhancement in an acidic solution |
US3523733A (en) * | 1966-01-05 | 1970-08-11 | Technicon Corp | Method and apparatus for particle counting |
US3427135A (en) * | 1966-07-11 | 1969-02-11 | Technicon Instr | Hematology apparatus |
-
1970
- 1970-10-30 US US00085333A patent/US3741875A/en not_active Expired - Lifetime
-
1971
- 1971-10-21 AU AU34847/71A patent/AU460469B2/en not_active Expired
- 1971-10-21 CA CA125,753A patent/CA960947A/en not_active Expired
- 1971-10-22 BE BE774311A patent/BE774311A/xx not_active IP Right Cessation
- 1971-10-26 GB GB4971771A patent/GB1331568A/en not_active Expired
- 1971-10-27 DE DE2153479A patent/DE2153479B2/de active Granted
- 1971-10-27 SE SE7113658A patent/SE372417B/xx unknown
- 1971-10-28 FR FR7138709A patent/FR2113336A5/fr not_active Expired
- 1971-10-28 IT IT30496/71A patent/IT961518B/it active
- 1971-10-29 SU SU711711809A patent/SU611598A3/ru active
- 1971-10-29 JP JP8567171A patent/JPS576932B1/ja active Pending
- 1971-11-01 NL NLAANVRAGE7114995,A patent/NL172463C/xx not_active IP Right Cessation
-
1980
- 1980-07-03 JP JP9002780A patent/JPS56163455A/ja active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4581223A (en) * | 1980-03-12 | 1986-04-08 | Lawrence Kass | Individual leukocyte determination by means of differential metachromatic dye sorption |
Also Published As
Publication number | Publication date |
---|---|
JPS576932B1 (ru) | 1982-02-08 |
AU3484771A (en) | 1973-05-03 |
IT961518B (it) | 1973-12-10 |
SE372417B (ru) | 1974-12-23 |
NL172463C (nl) | 1983-09-01 |
JPS56163455A (en) | 1981-12-16 |
DE2153479A1 (de) | 1972-05-04 |
DE2153479B2 (de) | 1975-06-05 |
US3741875A (en) | 1973-06-26 |
SU611598A3 (ru) | 1978-06-15 |
BE774311A (fr) | 1972-04-24 |
CA960947A (en) | 1975-01-14 |
AU460469B2 (en) | 1975-04-24 |
FR2113336A5 (ru) | 1972-06-23 |
NL7114995A (ru) | 1972-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PE20 | Patent expired after termination of 20 years |