FR2754712B1 - Compositions ophtalmiques - Google Patents

Compositions ophtalmiques

Info

Publication number
FR2754712B1
FR2754712B1 FR9612658A FR9612658A FR2754712B1 FR 2754712 B1 FR2754712 B1 FR 2754712B1 FR 9612658 A FR9612658 A FR 9612658A FR 9612658 A FR9612658 A FR 9612658A FR 2754712 B1 FR2754712 B1 FR 2754712B1
Authority
FR
France
Prior art keywords
ophthalmic compositions
glaucoma
treatment
acceptable salt
xanthan gum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9612658A
Other languages
English (en)
Other versions
FR2754712A1 (fr
Inventor
Gilles Chastaing
Bernard Plazonnet
Annouk Rozier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Original Assignee
Laboratories Merck Sharp and Dohme Chibret SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9612658A priority Critical patent/FR2754712B1/fr
Application filed by Laboratories Merck Sharp and Dohme Chibret SAS filed Critical Laboratories Merck Sharp and Dohme Chibret SAS
Priority to PCT/EP1997/005678 priority patent/WO1998017249A1/fr
Priority to JP51891698A priority patent/JP2001508035A/ja
Priority to AU48673/97A priority patent/AU715223B2/en
Priority to EP97911223A priority patent/EP0932389B1/fr
Priority to DE69715228T priority patent/DE69715228T2/de
Priority to CA002269552A priority patent/CA2269552A1/fr
Priority to AT97911223T priority patent/ATE223200T1/de
Priority to ES97911223T priority patent/ES2183148T3/es
Priority to US09/284,718 priority patent/US6264935B1/en
Priority to PE1997000898A priority patent/PE106998A1/es
Priority to ZA979219A priority patent/ZA979219B/xx
Priority to HR9612658A priority patent/HRP970552A2/hr
Publication of FR2754712A1 publication Critical patent/FR2754712A1/fr
Application granted granted Critical
Publication of FR2754712B1 publication Critical patent/FR2754712B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
FR9612658A 1996-10-17 1996-10-17 Compositions ophtalmiques Expired - Fee Related FR2754712B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR9612658A FR2754712B1 (fr) 1996-10-17 1996-10-17 Compositions ophtalmiques
AT97911223T ATE223200T1 (de) 1996-10-17 1997-10-09 Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel
AU48673/97A AU715223B2 (en) 1996-10-17 1997-10-09 Ophthalmic compositions containing a carbonic anhydrase inhibitor and xanthan gum
EP97911223A EP0932389B1 (fr) 1996-10-17 1997-10-09 Compositions ophtalmiques contenant un inhibiteur d'anhydrase carbonique et de la gomme de xanthane
DE69715228T DE69715228T2 (de) 1996-10-17 1997-10-09 Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel
CA002269552A CA2269552A1 (fr) 1996-10-17 1997-10-09 Compositions ophtalmiques contenant un inhibiteur d'anhydrase carbonique et de la gomme de xanthane
PCT/EP1997/005678 WO1998017249A1 (fr) 1996-10-17 1997-10-09 Compositions ophtalmiques contenant un inhibiteur d'anhydrase carbonique et de la gomme de xanthane
ES97911223T ES2183148T3 (es) 1996-10-17 1997-10-09 Composiciones oftalmicas que contienen un inhibidor de anhidrasa carbonica y de la goma de xantano.
US09/284,718 US6264935B1 (en) 1996-10-17 1997-10-09 Ophthalmic composition containing a carbonic anhydrase inhibitor and xanthan gum
JP51891698A JP2001508035A (ja) 1996-10-17 1997-10-09 炭酸脱水酵素阻害薬及びキサンタンガムを含有する眼科用組成物
PE1997000898A PE106998A1 (es) 1996-10-17 1997-10-10 Composiciones oftalmicas
ZA979219A ZA979219B (en) 1996-10-17 1997-10-15 Ophthalmic compositions containing a carbonic anhydrase inhibitor and xanthan gum
HR9612658A HRP970552A2 (en) 1996-10-17 1997-10-16 Ophthalmic compositions containing a carbonic anhydrase inhibitor and xanthan gum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9612658A FR2754712B1 (fr) 1996-10-17 1996-10-17 Compositions ophtalmiques

Publications (2)

Publication Number Publication Date
FR2754712A1 FR2754712A1 (fr) 1998-04-24
FR2754712B1 true FR2754712B1 (fr) 1999-09-03

Family

ID=9496748

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9612658A Expired - Fee Related FR2754712B1 (fr) 1996-10-17 1996-10-17 Compositions ophtalmiques

Country Status (13)

Country Link
US (1) US6264935B1 (fr)
EP (1) EP0932389B1 (fr)
JP (1) JP2001508035A (fr)
AT (1) ATE223200T1 (fr)
AU (1) AU715223B2 (fr)
CA (1) CA2269552A1 (fr)
DE (1) DE69715228T2 (fr)
ES (1) ES2183148T3 (fr)
FR (1) FR2754712B1 (fr)
HR (1) HRP970552A2 (fr)
PE (1) PE106998A1 (fr)
WO (1) WO1998017249A1 (fr)
ZA (1) ZA979219B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
MXPA02004349A (es) 1999-11-01 2003-09-22 Alcon Inc Composiciones farmaceuticas que contienen un farmaco antibiotico de fluoroquinolona y goma de xantano.
PT1305033E (pt) 2000-07-28 2005-01-31 Alcon Inc Composicoes farmaceuticas que contem tobramicina e goma de xantano
US20040067992A1 (en) * 2001-08-10 2004-04-08 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia
ES2393864T3 (es) * 2002-08-30 2012-12-28 Nycomed Gmbh El uso de la asociación de ciclesonida y antihistaminas para el tratamiento de rinitis alérgica
PT1572217E (pt) * 2002-12-12 2008-11-28 Nycomed Gmbh Medicamento combinado de r,r-formoterol e ciclesonida
PL1670482T5 (pl) * 2003-09-16 2022-10-03 Covis Pharma Gmbh Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego
EP1740188A1 (fr) * 2004-04-20 2007-01-10 Altana Pharma AG Utilisation de ciclesonide pour le traitement des maladies respiratoires chez des patients fumeurs
CN101031310B (zh) 2004-09-28 2010-10-27 千寿制药株式会社 含有黄原胶和氨基酸的眼科用组合物
ES2337501T3 (es) * 2005-07-11 2010-04-26 Senju Pharmaceutical Co., Ltd. Preparacion oftalmica que comprende goma de xantano y terpenoide.
EP1978926A2 (fr) * 2005-12-19 2008-10-15 Comentis, Inc. Preparations de mecamylamine topique pour administration oculaire et utilisations de celles-ci
KR101381035B1 (ko) * 2006-03-23 2014-04-04 센주 세이야꾸 가부시키가이샤 잔탄검 및 글루코스를 포함하는 안약 조성물
CA2659687A1 (fr) 2006-07-31 2008-02-07 Senju Pharmaceutical Co., Ltd. Preparation liquide aqueuse contenant un amide
US20110117189A1 (en) * 2008-07-08 2011-05-19 S.I.F.I. Societa' Industria Farmaceutica Italiana S.P.A. Ophthalmic compositions for treating pathologies of the posterior segment of the eye
JP2016537364A (ja) * 2013-11-15 2016-12-01 テバ ファーマシューティカル インダストリーズ リミティド ラキニモドを用いた緑内障の治療
EA034839B1 (ru) * 2014-10-20 2020-03-26 Сентисс Фарма Прайвет Лимитед Офтальмологический раствор
IT202000002296A1 (it) * 2020-02-06 2021-08-06 Sifi Spa Formulazioni topiche oftalmiche a base di xantano con ridotta posologia

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US5157044A (en) 1983-02-04 1992-10-20 University Of Iowa Research Foundation Analogs of carbonic anhydrase inhibitors and their use as topical IOP inhibitors
US4863922A (en) 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4876271A (en) 1988-12-20 1989-10-24 Merck & Co., Inc. Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors
US4929549A (en) 1989-02-08 1990-05-29 Merck & Co., Inc. 5-carbamoylthieno[2,3-b]thiophene-2-sulfon-amides as topically active carbonic anhydrase inhibitors
US5120757A (en) 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
FR2657018A1 (fr) 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
US5059613A (en) 1990-03-19 1991-10-22 Research Corporation Technologies, Inc. Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors
US5055480A (en) 1990-03-19 1991-10-08 Research Corporation Technologies, Inc. Topically active ocular gem-diacylthiadiazole sulfonamide carbonic anhydrase inhibitors
US5242937A (en) 1990-03-19 1993-09-07 Research Corporation Technologies, Inc. Topically active ocular thiadiazole sulfonamide carbonic anhydrase inhibitors
IE911192A1 (en) 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
CA2040460C (fr) 1990-05-01 1997-06-10 Tacey X. Viegas Distribution de medicaments au moyen de gels thermoreversibles
US5091409A (en) 1990-05-17 1992-02-25 Merck & Co., Inc. 4-alkylamino-6-(C3-5 -hydrocarbyl)thieno[2,3-B]thiopyran-2-sulfonamide-7,7-dioxides
US5093332A (en) 1990-10-01 1992-03-03 Merck & Co., Inc. Substituted thieno(2,3-b)(1,4)thiazine-6-sulfonamides as antiglaucoma agents
DE69212850T2 (de) 1991-01-15 1997-03-06 Alcon Lab Inc Verwendung von Karrageenan in topischen ophthalmologischen Zusammensetzungen
JP2536806B2 (ja) * 1991-03-27 1996-09-25 アルコン ラボラトリーズ インコーポレイテッド ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
JPH08501303A (ja) 1992-09-17 1996-02-13 アルコン ラボラトリーズ，インコーポレイテッド 局所用炭酸脱水酵素阻害剤組成物
SE9301877D0 (sv) * 1993-06-02 1993-06-02 Kabi Pharmacia Ab In situ gel for therapeutic use
JP2002521333A (ja) * 1998-07-21 2002-07-16 メルク エンド カムパニー インコーポレーテッド 高眼圧治療用眼薬組成物

Also Published As

Publication number Publication date
AU4867397A (en) 1998-05-15
HRP970552A2 (en) 1998-08-31
CA2269552A1 (fr) 1998-04-30
DE69715228T2 (de) 2003-06-05
EP0932389A1 (fr) 1999-08-04
ES2183148T3 (es) 2003-03-16
WO1998017249A1 (fr) 1998-04-30
ZA979219B (en) 1998-07-17
FR2754712A1 (fr) 1998-04-24
PE106998A1 (es) 1999-01-23
DE69715228D1 (de) 2002-10-10
US6264935B1 (en) 2001-07-24
AU715223B2 (en) 2000-01-20
JP2001508035A (ja) 2001-06-19
ATE223200T1 (de) 2002-09-15
EP0932389B1 (fr) 2002-09-04

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Legal Events

Date Code Title Description
ST Notification of lapse