DE69715228T2 - Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel - Google Patents

Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel

Info

Publication number
DE69715228T2
DE69715228T2 DE69715228T DE69715228T DE69715228T2 DE 69715228 T2 DE69715228 T2 DE 69715228T2 DE 69715228 T DE69715228 T DE 69715228T DE 69715228 T DE69715228 T DE 69715228T DE 69715228 T2 DE69715228 T2 DE 69715228T2
Authority
DE
Germany
Prior art keywords
xanthan gum
carboanhydrase
product containing
medicinal product
eye medicinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69715228T
Other languages
English (en)
Other versions
DE69715228D1 (de
Inventor
Gilles Chastaing
Bernard Plazonnet
Annouk Rozier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Original Assignee
Laboratories Merck Sharp and Dohme Chibret SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Merck Sharp and Dohme Chibret SAS filed Critical Laboratories Merck Sharp and Dohme Chibret SAS
Application granted granted Critical
Publication of DE69715228D1 publication Critical patent/DE69715228D1/de
Publication of DE69715228T2 publication Critical patent/DE69715228T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
DE69715228T 1996-10-17 1997-10-09 Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel Expired - Fee Related DE69715228T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9612658A FR2754712B1 (fr) 1996-10-17 1996-10-17 Compositions ophtalmiques
PCT/EP1997/005678 WO1998017249A1 (en) 1996-10-17 1997-10-09 Ophthalmic compositions containing a carbonic anhydrase inhibitor and xanthan gum

Publications (2)

Publication Number Publication Date
DE69715228D1 DE69715228D1 (de) 2002-10-10
DE69715228T2 true DE69715228T2 (de) 2003-06-05

Family

ID=9496748

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69715228T Expired - Fee Related DE69715228T2 (de) 1996-10-17 1997-10-09 Einen carboanhydrase-hemmer und xanthangummi enthaltendes augenarzneimittel

Country Status (13)

Country Link
US (1) US6264935B1 (de)
EP (1) EP0932389B1 (de)
JP (1) JP2001508035A (de)
AT (1) ATE223200T1 (de)
AU (1) AU715223B2 (de)
CA (1) CA2269552A1 (de)
DE (1) DE69715228T2 (de)
ES (1) ES2183148T3 (de)
FR (1) FR2754712B1 (de)
HR (1) HRP970552A2 (de)
PE (1) PE106998A1 (de)
WO (1) WO1998017249A1 (de)
ZA (1) ZA979219B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
CN1384745A (zh) 1999-11-01 2002-12-11 爱尔康公司 含有一种氟喹诺酮抗生素和黄原酸胶的药物组合物
EP1305033B1 (de) 2000-07-28 2004-10-20 Alcon, Inc Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi
US20040067992A1 (en) * 2001-08-10 2004-04-08 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia
EP2295062B1 (de) * 2002-08-30 2012-08-29 Nycomed GmbH Verwendung der Kombination von Ciclesonid und Antihistaminika zur Behandlung von allergischer Rhinitis
DE60323138D1 (de) * 2002-12-12 2008-10-02 Nycomed Gmbh Kombinationsarzneimittel aus r,r-formoterol und ciclesonide
ES2452691T5 (es) * 2003-09-16 2022-09-14 Covis Pharma Gmbh Uso de ciclesonida para el tratamiento de enfermedades respiratorias
JP2007533706A (ja) * 2004-04-20 2007-11-22 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 喫煙患者における呼吸器疾患の治療のためのシクレソニドの使用
EP1797888A4 (de) 2004-09-28 2009-12-16 Senju Pharma Co Ophthalmische zusammensetzung mit xanthangummi und aminosäure
US7998942B2 (en) * 2005-07-11 2011-08-16 Senju Pharamaceutical Co., Ltd. Eye drop preparation comprising xanthan gum and terpenoid
KR20080081175A (ko) * 2005-12-19 2008-09-08 코멘티스, 인코포레이티드 안구 투여를 위한 국소 메카밀라민 제형 및 그것의 사용
WO2007108541A1 (ja) 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
MX2009001037A (es) 2006-07-31 2009-05-15 Senju Pharma Co Preparacion liquida acuosa que contiene compuesto de amida.
WO2010004594A1 (en) * 2008-07-08 2010-01-14 S.I.F.I. Societa' Industria Farmaceutica Italiana S.P.A. Ophthalmic compositions for treating pathologies of the posterior segment of the eye
EP3068395A4 (de) * 2013-11-15 2017-07-12 Teva Pharmaceutical Industries Ltd. Behandlung von glaukom mit laquinimod
WO2016063184A1 (en) * 2014-10-20 2016-04-28 Sentiss Pharma Private Limited Ophthalmic solution
IT202000002296A1 (it) * 2020-02-06 2021-08-06 Sifi Spa Formulazioni topiche oftalmiche a base di xantano con ridotta posologia

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US5157044A (en) 1983-02-04 1992-10-20 University Of Iowa Research Foundation Analogs of carbonic anhydrase inhibitors and their use as topical IOP inhibitors
US4863922A (en) 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4876271A (en) 1988-12-20 1989-10-24 Merck & Co., Inc. Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors
US4929549A (en) 1989-02-08 1990-05-29 Merck & Co., Inc. 5-carbamoylthieno[2,3-b]thiophene-2-sulfon-amides as topically active carbonic anhydrase inhibitors
US5120757A (en) 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
FR2657018A1 (fr) 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
US5055480A (en) 1990-03-19 1991-10-08 Research Corporation Technologies, Inc. Topically active ocular gem-diacylthiadiazole sulfonamide carbonic anhydrase inhibitors
US5242937A (en) 1990-03-19 1993-09-07 Research Corporation Technologies, Inc. Topically active ocular thiadiazole sulfonamide carbonic anhydrase inhibitors
US5059613A (en) 1990-03-19 1991-10-22 Research Corporation Technologies, Inc. Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors
IE911192A1 (en) 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
CA2040460C (en) 1990-05-01 1997-06-10 Tacey X. Viegas Drug delivery with thermoreversible gels
US5091409A (en) 1990-05-17 1992-02-25 Merck & Co., Inc. 4-alkylamino-6-(C3-5 -hydrocarbyl)thieno[2,3-B]thiopyran-2-sulfonamide-7,7-dioxides
US5093332A (en) 1990-10-01 1992-03-03 Merck & Co., Inc. Substituted thieno(2,3-b)(1,4)thiazine-6-sulfonamides as antiglaucoma agents
ATE141502T1 (de) 1991-01-15 1996-09-15 Alcon Lab Inc Verwendung von karrageenan in topischen ophthalmologischen zusammensetzungen
CA2064160C (en) * 1991-03-27 1998-08-11 Paul J. T. Missel Use of combinations of gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
CA2141879A1 (en) 1992-09-17 1994-03-31 Thomas Robert Dean Topical carbonic anhydrase inhibitor composition
SE9301877D0 (sv) * 1993-06-02 1993-06-02 Kabi Pharmacia Ab In situ gel for therapeutic use
JP2002521333A (ja) * 1998-07-21 2002-07-16 メルク エンド カムパニー インコーポレーテッド 高眼圧治療用眼薬組成物

Also Published As

Publication number Publication date
FR2754712B1 (fr) 1999-09-03
ES2183148T3 (es) 2003-03-16
AU715223B2 (en) 2000-01-20
EP0932389A1 (de) 1999-08-04
HRP970552A2 (en) 1998-08-31
EP0932389B1 (de) 2002-09-04
WO1998017249A1 (en) 1998-04-30
JP2001508035A (ja) 2001-06-19
AU4867397A (en) 1998-05-15
CA2269552A1 (en) 1998-04-30
US6264935B1 (en) 2001-07-24
DE69715228D1 (de) 2002-10-10
ATE223200T1 (de) 2002-09-15
ZA979219B (en) 1998-07-17
PE106998A1 (es) 1999-01-23
FR2754712A1 (fr) 1998-04-24

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee