FR2563522B1 - Analogues de 7 oxabicycloheptane prostaglandines, a action anti-inflammatoire, analgesique et cardiovasculaire - Google Patents

Analogues de 7 oxabicycloheptane prostaglandines, a action anti-inflammatoire, analgesique et cardiovasculaire

Info

Publication number
FR2563522B1
FR2563522B1 FR8506325A FR8506325A FR2563522B1 FR 2563522 B1 FR2563522 B1 FR 2563522B1 FR 8506325 A FR8506325 A FR 8506325A FR 8506325 A FR8506325 A FR 8506325A FR 2563522 B1 FR2563522 B1 FR 2563522B1
Authority
FR
France
Prior art keywords
oxabicycloheptane
prostaglandins
analgesic
analogs
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8506325A
Other languages
English (en)
Other versions
FR2563522A1 (fr
Inventor
Steven E Hall
Martin F Haslanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2563522A1 publication Critical patent/FR2563522A1/fr
Application granted granted Critical
Publication of FR2563522B1 publication Critical patent/FR2563522B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR8506325A 1984-04-27 1985-04-25 Analogues de 7 oxabicycloheptane prostaglandines, a action anti-inflammatoire, analgesique et cardiovasculaire Expired FR2563522B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/604,717 US4542157A (en) 1984-04-27 1984-04-27 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Publications (2)

Publication Number Publication Date
FR2563522A1 FR2563522A1 (fr) 1985-10-31
FR2563522B1 true FR2563522B1 (fr) 1986-12-19

Family

ID=24420735

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8506325A Expired FR2563522B1 (fr) 1984-04-27 1985-04-25 Analogues de 7 oxabicycloheptane prostaglandines, a action anti-inflammatoire, analgesique et cardiovasculaire

Country Status (7)

Country Link
US (1) US4542157A (fr)
JP (1) JPS60233086A (fr)
CA (1) CA1256888A (fr)
DE (1) DE3515208A1 (fr)
FR (1) FR2563522B1 (fr)
GB (1) GB2158064B (fr)
IT (1) IT1217295B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines
US4749715A (en) * 1987-03-02 1988-06-07 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted amino prostaglandin analogs
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
EP2063905B1 (fr) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0013607B1 (fr) * 1979-01-05 1983-03-23 National Research Development Corporation Bicyclo (2,2,1)heptanes et bicyclo (2,2,1) hept-2-ènes substitués et leurs compositions pharmaceutiques
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines

Also Published As

Publication number Publication date
IT8520453A0 (it) 1985-04-23
JPS60233086A (ja) 1985-11-19
IT1217295B (it) 1990-03-22
DE3515208A1 (de) 1985-10-31
GB2158064A (en) 1985-11-06
GB8509009D0 (en) 1985-05-15
US4542157A (en) 1985-09-17
GB2158064B (en) 1987-10-07
CA1256888A (fr) 1989-07-04
FR2563522A1 (fr) 1985-10-31

Similar Documents

Publication Publication Date Title
IT1178140B (it) Procedimento per produrre un catetere con punta morbida deformabile e prodotto ottenuto
MX164103B (es) Mejoras a dentifrico anhidro
FR2574135B1 (fr) Cheville a expansion par cone
DK72885A (da) Pleuromutilinderivater
FR2574794B1 (fr) Analogues de prostaglandines tetrahydrothienyl-substitues a action cardiovasculaire
FR2585703B1 (fr) 7-oxabicycloheptane amides-thioamides, analogues de prostaglandines, a action cardio-vasculaire
FR2563522B1 (fr) Analogues de 7 oxabicycloheptane prostaglandines, a action anti-inflammatoire, analgesique et cardiovasculaire
IT8419267A0 (it) Carbammati sostituiti con 7-ossabicicloeptano analoghi delle prostaglandine.
FR2611718B1 (fr) Analogues d'amino prostaglandines 7-oxabicycloheptane substitues, a action therapeutique
IT8567722A0 (it) Analoghi della mitomicina 6 sostituiti
NZ211676A (en) 7-oxabicycloheptane substituted prostaglandin analogues
ES547776A0 (es) Una composicion de toluenodiamina
IT1164189B (it) Analoghi della vasologhi della vasopressina
FR2558836B1 (fr) Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique
FR2568213B1 (fr) Ensemble pedale-chaussure du type comportant un cale-pedale
FR2598419B1 (fr) Analogues d'amido-carbamoyl prostaglandines 7-oxabicycloheptane substitues, a action therapeutique
FR2580651B1 (fr) Analogues de thio-prostaglandines 7-oxabicycloheptane-substitues, a action therapeutique
FR2577927B1 (fr) Analogues de prostaglandines a substituant 7-oxabicycloheptane, a proprietes therapeutiques
IT8619456A0 (it) Analoghi di prostaglandine sostituiti con tiabicicloeptano avenyi attivita' cardiovascolare.
FR2577928B1 (fr) Analogues d'amino-prostaglandines a substituant thiabicycloheptane
FR2587343B1 (fr) Analogues de 7-oxabicycloheptane oxa prostaglandines a action therapeutique
MX161396A (es) Mejoras a cigarrillos con boquilla
IT1198157B (it) Procedimento per riprendere la filatura di un filo
IT8620163A0 (it) Analoghi di prostaglandine 7-ossabicicloeptano sostituiti.
MX163219B (es) Mejoras a dentifrico

Legal Events

Date Code Title Description
ST Notification of lapse