FR2558836B1 - Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique - Google Patents

Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique

Info

Publication number
FR2558836B1
FR2558836B1 FR8500991A FR8500991A FR2558836B1 FR 2558836 B1 FR2558836 B1 FR 2558836B1 FR 8500991 A FR8500991 A FR 8500991A FR 8500991 A FR8500991 A FR 8500991A FR 2558836 B1 FR2558836 B1 FR 2558836B1
Authority
FR
France
Prior art keywords
oxabicyloheptane
oxaprostaglandin
analogs
substituted
therapeutic action
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8500991A
Other languages
English (en)
Other versions
FR2558836A1 (fr
Inventor
Steven E Hall
Martin F Haslanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2558836A1 publication Critical patent/FR2558836A1/fr
Application granted granted Critical
Publication of FR2558836B1 publication Critical patent/FR2558836B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR8500991A 1984-01-26 1985-01-24 Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique Expired FR2558836B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/574,000 US4526900A (en) 1984-01-26 1984-01-26 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease

Publications (2)

Publication Number Publication Date
FR2558836A1 FR2558836A1 (fr) 1985-08-02
FR2558836B1 true FR2558836B1 (fr) 1986-12-19

Family

ID=24294275

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8500991A Expired FR2558836B1 (fr) 1984-01-26 1985-01-24 Analogues d'oxaprostaglandines a substituant 7-oxabicyloheptane, a action therapeutique

Country Status (7)

Country Link
US (1) US4526900A (fr)
JP (1) JPS60178874A (fr)
CA (1) CA1257285A (fr)
DE (1) DE3502512A1 (fr)
FR (1) FR2558836B1 (fr)
GB (1) GB2153352B (fr)
IT (1) IT1208493B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines
JPH01145594A (ja) * 1987-12-01 1989-06-07 Nippon Denso Co Ltd 対人追従装置
EP2147679B1 (fr) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions pour le transport de barrière hématoencéphalique
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008036682A2 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
WO1980001381A1 (fr) * 1979-01-05 1980-07-10 R Jones Bicyclo (2,2,1) heptanes et hep-2-enes substitues
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins
US4416896A (en) * 1982-05-17 1983-11-22 E. R. Squibb & Sons, Inc. 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease
CA1256887A (fr) * 1983-03-14 1989-07-04 Steven E. Hall 7-oxabicycloheptanes substitues analogues de prostaglandines

Also Published As

Publication number Publication date
IT8519224A0 (it) 1985-01-25
IT1208493B (it) 1989-07-10
GB2153352B (en) 1987-10-07
GB8501266D0 (en) 1985-02-20
GB2153352A (en) 1985-08-21
FR2558836A1 (fr) 1985-08-02
CA1257285A (fr) 1989-07-11
JPS60178874A (ja) 1985-09-12
DE3502512A1 (de) 1985-08-01
US4526900A (en) 1985-07-02

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Legal Events

Date Code Title Description
ST Notification of lapse