FR2463771B1 - - Google Patents
Info
- Publication number
- FR2463771B1 FR2463771B1 FR8018279A FR8018279A FR2463771B1 FR 2463771 B1 FR2463771 B1 FR 2463771B1 FR 8018279 A FR8018279 A FR 8018279A FR 8018279 A FR8018279 A FR 8018279A FR 2463771 B1 FR2463771 B1 FR 2463771B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10677679A JPS5630964A (en) | 1979-08-22 | 1979-08-22 | Novel substituted quinolinecarboxylic acid and its preparation |
| BE2/58706A BE884824A (en) | 1979-08-22 | 1980-08-19 | QUINOLEINE-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION |
| BE2059018 | 1981-02-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2463771A1 FR2463771A1 (en) | 1981-02-27 |
| FR2463771B1 true FR2463771B1 (en) | 1983-04-22 |
Family
ID=27159608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8018279A Granted FR2463771A1 (en) | 1979-08-22 | 1980-08-21 | PROCESS FOR THE PREPARATION OF QUINOLINECARBOXYLIC ACID DERIVATIVES AND NOVEL PRODUCTS OBTAINED WITH ANTIBACTERIAL ACTIVITY |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5630964A (en) |
| AU (1) | AU533141B2 (en) |
| BE (2) | BE884824A (en) |
| CA (1) | CA1159454A (en) |
| CH (1) | CH645641A5 (en) |
| DE (1) | DE3031767C3 (en) |
| ES (1) | ES494352A0 (en) |
| FR (1) | FR2463771A1 (en) |
| GB (1) | GB2057440B (en) |
| HK (1) | HK98486A (en) |
| HU (1) | HU184817B (en) |
| IT (1) | IT1132392B (en) |
| MY (1) | MY8700155A (en) |
| SE (1) | SE440353B (en) |
| SG (1) | SG71386G (en) |
| SU (2) | SU978727A3 (en) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4416884A (en) * | 1978-04-12 | 1983-11-22 | Otsuka Pharmaceutical Co., Ltd. | Piperazinylbenzoheterocyclic compounds |
| NO156828C (en) * | 1980-11-10 | 1987-12-02 | Otsuka Pharma Co Ltd | ANALOGY PROCEDURE FOR THE PREPARATION OF ANTIBACTERYLY EFFECTIVE BENZOHETEROCYCLIC COMPOUNDS. |
| JPS57176987A (en) * | 1981-04-24 | 1982-10-30 | Otsuka Pharmaceut Co Ltd | Pyrrolo(3,2,1-ij)quinoline-5-carboxylic acid derivative |
| SE440354B (en) * | 1981-02-19 | 1985-07-29 | Kyorin Seiyaku Kk | quinolinecarboxylic |
| JPS58105965A (en) * | 1981-12-15 | 1983-06-24 | Nippon Shinyaku Co Ltd | Substituted quinolinecarboxylic acid derivative |
| US4472406A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives |
| US4472405A (en) * | 1982-11-12 | 1984-09-18 | Riker Laboratories, Inc. | Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives |
| JPS59128383A (en) * | 1982-12-29 | 1984-07-24 | Kanebo Ltd | Novel quinolinecarboxylic acid derivative and antibacterial agent containing said compound as active component |
| JPS59155381A (en) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | Benzoquinolizinecarboxylic acid derivative and its preparation |
| DE3308908A1 (en) * | 1983-03-12 | 1984-09-13 | Bayer Ag, 5090 Leverkusen | BACTERICIDAL AGENTS |
| DE3318145A1 (en) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-AMINO-1-CYCLOPROPYL-6,8-DIFLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS |
| JPS59195842U (en) * | 1983-06-13 | 1984-12-26 | クラリオン株式会社 | radio receiver |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| GB8412094D0 (en) * | 1984-05-11 | 1984-06-20 | Scras | Quinoline derivatives |
| DE3420743A1 (en) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-AMINO-1-CYCLOPROPYL-6,8-DIHALOGEN-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS |
| US5468861A (en) * | 1984-06-04 | 1995-11-21 | Bayer Aktiengesellschaft | 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and alkyl esters thereof |
| US4550104A (en) * | 1984-07-20 | 1985-10-29 | Warner-Lambert Company | Antibacterial thiazolo-quinolines and thiazolo-naphthyridines |
| US4550103A (en) * | 1984-07-20 | 1985-10-29 | Warner-Lambert Company | Antibacterial 1-oxo-benzoquinolizine-2-carboxylic acids |
| JPS61118370A (en) * | 1985-10-30 | 1986-06-05 | Kyorin Pharmaceut Co Ltd | Quinolonecarboxylic acid and its preparation |
| ZA859283B (en) * | 1984-12-06 | 1987-07-29 | Pfizer | Substituted dihydroquinolone carboxylic acids and anti-bacterial compositions containing them |
| JPS61143363A (en) * | 1984-12-17 | 1986-07-01 | Kyorin Pharmaceut Co Ltd | Production of quinolonecarboxylic acid derivative |
| JPS61143364A (en) * | 1984-12-17 | 1986-07-01 | Kyorin Pharmaceut Co Ltd | Production of quinolonecarboxylic acid derivative |
| JPS61205258A (en) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceut Co Ltd | Quinolonecarboxylic acid derivative and production thereof |
| AU5427286A (en) * | 1985-03-08 | 1986-09-11 | Kyorin Pharmaceutical Co. Ltd. | 7-(1-pyrrolidinyl)-3-quinolinecarboxylic acid derivatives |
| ATE77373T1 (en) * | 1985-03-21 | 1992-07-15 | Kyorin Seiyaku Kk | PROCESS FOR THE PREPARATION OF QUINOLINE ACID DERIVATIVES. |
| GB8512143D0 (en) * | 1985-05-14 | 1985-06-19 | Beecham Group Plc | Method of treatment |
| US4686221A (en) * | 1985-10-01 | 1987-08-11 | Kanebo, Ltd. | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same |
| JPS62228063A (en) * | 1985-12-27 | 1987-10-06 | Sankyo Co Ltd | Quinolinecarboxylic acid derivative |
| DE3705621C2 (en) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclic substituted quinolonecarboxylic acid derivatives |
| JPH0753715B2 (en) * | 1986-02-25 | 1995-06-07 | 大塚製薬株式会社 | Benzoheterocyclic compound |
| JPS62205060A (en) * | 1986-03-04 | 1987-09-09 | Kyorin Pharmaceut Co Ltd | 8-substituted quinolonecarboxylic acid derivative |
| JPS62215572A (en) * | 1986-03-17 | 1987-09-22 | Kyorin Pharmaceut Co Ltd | Quinolone carboxylic acid derivative |
| ZA874696B (en) * | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
| US5591744A (en) * | 1987-04-16 | 1997-01-07 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
| JPS6483068A (en) * | 1987-09-25 | 1989-03-28 | Otsuka Pharma Co Ltd | Production of benzo-heterocyclic compound |
| JPH01175936A (en) * | 1987-12-28 | 1989-07-12 | Kyorin Pharmaceut Co Ltd | Tablet containing 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-4-methyl-1-pi-perazinyl)-4-oxo-3-quinolinecarboxylic acid as active component |
| JP2526128B2 (en) * | 1988-08-08 | 1996-08-21 | エスエス製薬株式会社 | Quinolonecarboxylic acid derivative |
| WO1991001308A1 (en) * | 1989-07-21 | 1991-02-07 | Ss Pharmaceutical Co., Ltd. | Quinolonecarboxylic acid derivatives |
| US5185337A (en) * | 1989-03-29 | 1993-02-09 | Otsuka Pharmaceutical Co., Ltd. | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use |
| FR2655545B1 (en) * | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | NEW THERAPEUTIC APPLICATION OF FLUOROQUINOLONE DERIVATIVES. |
| FR2656611B1 (en) * | 1990-01-04 | 1992-05-07 | Hoechst France | NEW QUINOLONES, THEIR SALTS, USEFUL AS ANTIMICROBIAL AGENTS, PREPARATION METHOD AND THEIR APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM. |
| FR2673426B1 (en) * | 1991-03-01 | 1993-07-16 | Bouchara Sa | NEW QUINOLONES, THEIR PREPARATION PROCESS AND THE CLOSING COMPOSITIONS. |
| FR2675144B1 (en) * | 1991-04-10 | 1995-06-16 | Bouchara Sa | NEW DIFLUORINATED QUINOLONES - THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. |
| US5532239A (en) * | 1993-08-02 | 1996-07-02 | Assistance Publique - Hopitaux De Paris | Therapeutic application of fluoroquinolone derivatives |
| US5731440A (en) * | 1994-03-01 | 1998-03-24 | Ishihara Sangyo Kaisha Ltd. | Intermediates for producing 5,7-dichloro-4-hydroxyquinoline |
| SE9904108D0 (en) * | 1999-11-15 | 1999-11-15 | New Pharma Research Ab | New compounds |
| US7973022B2 (en) | 2006-02-17 | 2011-07-05 | Idexx Laboratories, Inc. | Fluoroquinolone carboxylic acid salt compositions |
| US20070197548A1 (en) | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA947301A (en) * | 1970-01-28 | 1974-05-14 | Sumitomo Chemical Company | Process for the preparation of compound having antibacterial action |
| BE793524A (en) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES |
| US4156726A (en) * | 1974-12-07 | 1979-05-29 | Fisons Limited | 4-Oxo-2-carboxyl quinoline derivatives used as antiallergic compounds |
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| JPS54112877A (en) | 1978-02-20 | 1979-09-04 | Sumitomo Chem Co Ltd | Preparation of 1-substituted-1,4-dihydro-4-oxo-3-pyridine carboxylic acid derivatives |
| DE2914258A1 (en) * | 1978-04-12 | 1979-10-25 | Otsuka Pharma Co Ltd | PIPERAZINYLBENZOHETEROCYCLIC COMPOUNDS, METHODS OF PREPARING THEREOF, AND AGENTS CONTAINING THEM |
| AU553415B2 (en) * | 1983-09-19 | 1986-07-17 | Abbott Japan Co., Ltd. | 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids |
-
1979
- 1979-08-22 JP JP10677679A patent/JPS5630964A/en active Pending
-
1980
- 1980-08-04 SE SE8005534A patent/SE440353B/en not_active IP Right Cessation
- 1980-08-06 AU AU61122/80A patent/AU533141B2/en not_active Expired
- 1980-08-11 IT IT24111/80A patent/IT1132392B/en active
- 1980-08-14 CH CH614680A patent/CH645641A5/en not_active IP Right Cessation
- 1980-08-19 ES ES494352A patent/ES494352A0/en active Granted
- 1980-08-19 BE BE2/58706A patent/BE884824A/en not_active IP Right Cessation
- 1980-08-21 FR FR8018279A patent/FR2463771A1/en active Granted
- 1980-08-21 CA CA000358778A patent/CA1159454A/en not_active Expired
- 1980-08-21 SU SU802968349A patent/SU978727A3/en active
- 1980-08-21 HU HU802072A patent/HU184817B/en unknown
- 1980-08-22 DE DE3031767A patent/DE3031767C3/en not_active Expired - Lifetime
- 1980-08-22 GB GB8027372A patent/GB2057440B/en not_active Expired
-
1981
- 1981-02-19 BE BE2/59018A patent/BE887574R/en not_active IP Right Cessation
- 1981-03-03 SU SU813254244A patent/SU1015827A3/en active
-
1986
- 1986-09-04 SG SG713/86A patent/SG71386G/en unknown
- 1986-12-18 HK HK984/86A patent/HK98486A/en not_active IP Right Cessation
-
1987
- 1987-12-30 MY MY155/87A patent/MY8700155A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG71386G (en) | 1987-03-27 |
| ES8104233A1 (en) | 1981-04-16 |
| SU1015827A3 (en) | 1983-04-30 |
| FR2463771A1 (en) | 1981-02-27 |
| BE884824A (en) | 1980-12-16 |
| SE8005534L (en) | 1981-02-23 |
| DE3031767A1 (en) | 1981-03-26 |
| SE440353B (en) | 1985-07-29 |
| ES494352A0 (en) | 1981-04-16 |
| GB2057440A (en) | 1981-04-01 |
| IT1132392B (en) | 1986-07-02 |
| GB2057440B (en) | 1983-10-12 |
| MY8700155A (en) | 1987-12-31 |
| DE3031767C2 (en) | 1994-04-14 |
| DE3031767C3 (en) | 1994-04-14 |
| HK98486A (en) | 1986-12-24 |
| CA1159454A (en) | 1983-12-27 |
| SU978727A3 (en) | 1982-11-30 |
| AU6112280A (en) | 1981-02-26 |
| HU184817B (en) | 1984-10-29 |
| CH645641A5 (en) | 1984-10-15 |
| AU533141B2 (en) | 1983-11-03 |
| BE887574R (en) | 1981-06-15 |
| IT8024111A0 (en) | 1980-08-11 |
| JPS5630964A (en) | 1981-03-28 |