FR2419288A1 - Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments - Google Patents

Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments

Info

Publication number
FR2419288A1
FR2419288A1 FR7905872A FR7905872A FR2419288A1 FR 2419288 A1 FR2419288 A1 FR 2419288A1 FR 7905872 A FR7905872 A FR 7905872A FR 7905872 A FR7905872 A FR 7905872A FR 2419288 A1 FR2419288 A1 FR 2419288A1
Authority
FR
France
Prior art keywords
fluoruracil
obtaining
application
new derivatives
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7905872A
Other languages
English (en)
Other versions
FR2419288B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elkawi AG
Original Assignee
Elkawi AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elkawi AG filed Critical Elkawi AG
Publication of FR2419288A1 publication Critical patent/FR2419288A1/fr
Application granted granted Critical
Publication of FR2419288B1 publication Critical patent/FR2419288B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Nouveaux dérivés du 5-fluoruracile, leur procédé d'obtention et leur application en tant que médicaments. Les composés de l'invention répondent à la formule générale :
FR7905872A 1978-03-09 1979-03-07 Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments Granted FR2419288A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH254978A CH633280A5 (de) 1978-03-09 1978-03-09 5-fluoruracil-derivate und diese verbindungen enthaltende arzneimittel.

Publications (2)

Publication Number Publication Date
FR2419288A1 true FR2419288A1 (fr) 1979-10-05
FR2419288B1 FR2419288B1 (fr) 1982-11-05

Family

ID=4236289

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7905872A Granted FR2419288A1 (fr) 1978-03-09 1979-03-07 Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments

Country Status (5)

Country Link
JP (1) JPS54130586A (fr)
CH (1) CH633280A5 (fr)
DE (1) DE2854008A1 (fr)
FR (1) FR2419288A1 (fr)
GB (1) GB2017082B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5668674A (en) * 1979-11-08 1981-06-09 Shionogi & Co Ltd 5-fluorouracil derivative
JPS5738774A (en) * 1980-08-19 1982-03-03 Chugai Pharmaceut Co Ltd Uracil derivative and its preparation
JPS57179188A (en) * 1981-04-28 1982-11-04 Shionogi & Co Ltd 5-fluorouracil derivative
DE60229779D1 (de) * 2001-12-31 2008-12-18 Hans Rudolf Pfaendler Langkettige fettalkoholsubstituenten in mitteln gegen krebs
EP1939186A1 (fr) * 2006-12-22 2008-07-02 Sulfidris S.r.l. Derives de 5-Fluorouracil come agent anticancéreux
JP2011231015A (ja) * 2008-08-29 2011-11-17 Taiho Yakuhin Kogyo Kk 含窒素複素環を有する新規ウラシル化合物又はその塩

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5037787A (fr) * 1973-08-11 1975-04-08
JPS5119778A (en) * 1974-08-09 1976-02-17 Mitsui Seiyaku Kogyo Kk 11 chikan 55 furuororashiruruino seizoho

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5037787A (fr) * 1973-08-11 1975-04-08
JPS5119778A (en) * 1974-08-09 1976-02-17 Mitsui Seiyaku Kogyo Kk 11 chikan 55 furuororashiruruino seizoho

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1976 *

Also Published As

Publication number Publication date
GB2017082B (en) 1982-07-21
GB2017082A (en) 1979-10-03
JPS54130586A (en) 1979-10-09
CH633280A5 (de) 1982-11-30
FR2419288B1 (fr) 1982-11-05
DE2854008A1 (de) 1979-09-13

Similar Documents

Publication Publication Date Title
FR2390428A1 (fr) Nouveaux composes polyeniques, leur preparation et leur application en tant que medicaments
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
FR2398748A1 (fr) Nouveaux derives d'imidazoquinazoline, leur preparation et leur application en tant que medicaments
FR2422634A1 (fr) Isosteres de type 9-desoxy-9a-methylene de pgi2, utiles comme medicaments, et leur procede de preparation
FR2400512A1 (fr) Nouveaux nitro-imidazoles, leur preparation et leur application en tant que medicaments
FR2422643A1 (fr) Nouveaux derives d'imidazolidine, leur preparation et leur application comme medicaments
FR2360601A1 (fr) Nouveaux derives d'acides phosphoneux, leur preparation et leur application en tant que medicaments
FR2374307A1 (fr) Derives de la 1,4-dihydropyridine, leur procede d'obtention et composition pharmaceutique les contenant
FR2403330A1 (fr) Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments
FR2370744A1 (fr) Nouveaux derives d'aminopropanol, procede pour leur preparation et medicaments contenant ces composes
FR2377419A1 (fr) Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament
FR2415103A1 (fr) Acides et derives d'acides 4-pyridone-3-carboxyliques, leur preparation et leur application en tant que medicaments
FR2419288A1 (fr) Nouveaux derives du 5-fluoruracile, leur procede d'obtention et leur application en tant que medicaments
FR2384775A1 (fr) Derives de la morphine, leur procede de preparation et leur application comme medicament
FR2370745A1 (fr) Nouveaux derives de la morphanthridine, leur preparation et leur application comme medicaments
FR2379538A1 (fr) Nouveaux derives d'oxadiazolopyrimidine, leur preparation et leur application en tant que medicaments
FR2388799A1 (fr) Derives de pyridazinone, leur procede de preparation et leur application comme medicaments
FR2355012A1 (fr) Nouveaux derives de dihydro- et tetrahydro-iminothiazine, et leur application en tant que medicaments
FR2401160A1 (fr) Nouveaux derives d'esters de vincaminol, leur preparation et leur application en tant que medicaments
FR2401139A2 (fr) Nouveaux derives d5 de prostaglandines, leur procede de preparation et medicaments les contenant
FR2421181A1 (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
FR2375211A1 (fr) Nouveaux acides sulfamoylbenzoiques, leur preparation et leur application en tant que medicaments
FR2367065A1 (fr) Nouveaux composes du type 1-amino-2-hydroxy-3-heterocyclyloxy-propane utiles en tant que medicaments et leur procede de preparation
FR2432506A1 (fr) Nouveaux derives de 6-methoxy-2-acetylnaphtalene oxime, leur preparation et leur application en tant que medicaments
FR2396748A1 (fr) Nouveaux derives de prostaglandine, leur preparation et leur application en tant que medicaments

Legal Events

Date Code Title Description
ST Notification of lapse