DE60229779D1 - Langkettige fettalkoholsubstituenten in mitteln gegen krebs - Google Patents
Langkettige fettalkoholsubstituenten in mitteln gegen krebsInfo
- Publication number
- DE60229779D1 DE60229779D1 DE60229779T DE60229779T DE60229779D1 DE 60229779 D1 DE60229779 D1 DE 60229779D1 DE 60229779 T DE60229779 T DE 60229779T DE 60229779 T DE60229779 T DE 60229779T DE 60229779 D1 DE60229779 D1 DE 60229779D1
- Authority
- DE
- Germany
- Prior art keywords
- omega
- subsidies
- long
- against cancer
- agents against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005837 1,2-cyclopentylene group Chemical group [H]C1([H])C([H])([H])C([H])([*:1])C([H])([*:2])C1([H])[H] 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000651 prodrug Chemical class 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01131049 | 2001-12-31 | ||
PCT/EP2002/014809 WO2003055864A1 (en) | 2001-12-31 | 2002-12-30 | Long chain fatty alcohol substituents in antineoplastic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60229779D1 true DE60229779D1 (de) | 2008-12-18 |
Family
ID=8179720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60229779T Expired - Lifetime DE60229779D1 (de) | 2001-12-31 | 2002-12-30 | Langkettige fettalkoholsubstituenten in mitteln gegen krebs |
Country Status (9)
Country | Link |
---|---|
US (1) | US20040266747A1 (de) |
EP (1) | EP1465876B1 (de) |
JP (1) | JP2005513156A (de) |
AT (1) | ATE413390T1 (de) |
AU (1) | AU2002367194B2 (de) |
CA (1) | CA2464937A1 (de) |
DE (1) | DE60229779D1 (de) |
ES (1) | ES2316651T3 (de) |
WO (1) | WO2003055864A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005105153A1 (en) * | 2004-04-30 | 2005-11-10 | Kopran Research Laboratories Limited | Hydroxyalkyl derivatives of biologically active compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH633280A5 (de) * | 1978-03-09 | 1982-11-30 | Elkawi Ag | 5-fluoruracil-derivate und diese verbindungen enthaltende arzneimittel. |
JPS5668674A (en) * | 1979-11-08 | 1981-06-09 | Shionogi & Co Ltd | 5-fluorouracil derivative |
EP0167310B1 (de) * | 1984-06-27 | 1991-05-29 | Johnson Matthey Public Limited Company | Platinkoordinationsverbindungen |
DE3432320A1 (de) * | 1984-09-03 | 1986-03-13 | Behringwerke Ag, 3550 Marburg | Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel |
GB9322795D0 (en) * | 1993-11-05 | 1993-12-22 | Wellcome Found | Novel compounds |
AU1608801A (en) * | 1999-11-15 | 2001-05-30 | Parker Hughes Institute | Diamino platinum (ii) antitumor complexes |
-
2002
- 2002-12-30 WO PCT/EP2002/014809 patent/WO2003055864A1/en active Application Filing
- 2002-12-30 AU AU2002367194A patent/AU2002367194B2/en not_active Ceased
- 2002-12-30 EP EP02805778A patent/EP1465876B1/de not_active Expired - Lifetime
- 2002-12-30 AT AT02805778T patent/ATE413390T1/de not_active IP Right Cessation
- 2002-12-30 US US10/494,441 patent/US20040266747A1/en not_active Abandoned
- 2002-12-30 ES ES02805778T patent/ES2316651T3/es not_active Expired - Lifetime
- 2002-12-30 JP JP2003556395A patent/JP2005513156A/ja active Pending
- 2002-12-30 DE DE60229779T patent/DE60229779D1/de not_active Expired - Lifetime
- 2002-12-30 CA CA002464937A patent/CA2464937A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2002367194B2 (en) | 2008-10-30 |
WO2003055864A1 (en) | 2003-07-10 |
EP1465876A1 (de) | 2004-10-13 |
ATE413390T1 (de) | 2008-11-15 |
CA2464937A1 (en) | 2003-07-10 |
AU2002367194A1 (en) | 2003-07-15 |
ES2316651T3 (es) | 2009-04-16 |
EP1465876B1 (de) | 2008-11-05 |
JP2005513156A (ja) | 2005-05-12 |
US20040266747A1 (en) | 2004-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |