FR2406999A1 - Stabilisant pour polysaccharides de meningocoques - Google Patents
Stabilisant pour polysaccharides de meningocoquesInfo
- Publication number
- FR2406999A1 FR2406999A1 FR7830616A FR7830616A FR2406999A1 FR 2406999 A1 FR2406999 A1 FR 2406999A1 FR 7830616 A FR7830616 A FR 7830616A FR 7830616 A FR7830616 A FR 7830616A FR 2406999 A1 FR2406999 A1 FR 2406999A1
- Authority
- FR
- France
- Prior art keywords
- stabilizer
- meningococcal polysaccharides
- lactose
- addition
- meningococcal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Abstract
POUR AMELIORER LA STABILITE DE POLYSACCHARIDES DE MENINGOCOQUES EN SOLUTION AQUEUSE, L'ADDITION CONNUE DE LACTOSE EST REMPLACEE TOTALEMENT OU PARTIELLEMENT PAR L'ADDITION D'UN AUTRE COMPOSE FORMATEUR D'HYDRATE QUI PEUT ETRE DESHYDRATE DE MANIERE REVERSIBLE DANS LES CONDITIONS DE LYOPHYLISATION. ON PEUT ENSUITE SECHER LE MELANGE ETOU LE CONFECTIONNER EN UN VACCIN. LE COMPOSE EST, PAR EXEMPLE, LE SACCHAROSE, LE RAFFINOSE, LE GLUCOSE, LE TREHALOSE, UN GLYCEROPHOSPHATE OU UN GLUTAMINATE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772748132 DE2748132A1 (de) | 1977-10-27 | 1977-10-27 | Stabilisator fuer polysaccharid |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2406999A1 true FR2406999A1 (fr) | 1979-05-25 |
FR2406999B1 FR2406999B1 (fr) | 1982-11-12 |
Family
ID=6022367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7830616A Granted FR2406999A1 (fr) | 1977-10-27 | 1978-10-27 | Stabilisant pour polysaccharides de meningocoques |
Country Status (11)
Country | Link |
---|---|
US (1) | US4206200A (fr) |
JP (1) | JPS5470422A (fr) |
BE (1) | BE871612A (fr) |
CA (1) | CA1113861A (fr) |
DE (1) | DE2748132A1 (fr) |
DK (1) | DK158006C (fr) |
ES (1) | ES474412A1 (fr) |
FI (1) | FI61807B (fr) |
FR (1) | FR2406999A1 (fr) |
GB (1) | GB2009198B (fr) |
SE (1) | SE447700B (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0072513A2 (fr) * | 1981-08-14 | 1983-02-23 | Smithkline Biologicals S.A. | Procédé de préparation de polysaccharides bactériens capsulaires antigéniques purifiés, produits obtenus et leur utilisation |
WO1987000196A1 (fr) * | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection des proteines et similaires |
GB2187191A (en) * | 1984-01-30 | 1987-09-03 | Quadrant Bioresources Ltd | Protection of proteins and the like |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4451446A (en) * | 1982-03-04 | 1984-05-29 | Smithkline-Rit | Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them |
US4931385A (en) * | 1985-06-24 | 1990-06-05 | Hygeia Sciences, Incorporated | Enzyme immunoassays and immunologic reagents |
US4868108A (en) * | 1985-12-12 | 1989-09-19 | Hygeia Sciences, Incorporated | Multiple-antibody detection of antigen |
US4678812A (en) * | 1986-05-30 | 1987-07-07 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
US4762857A (en) * | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
US5102788A (en) * | 1988-11-21 | 1992-04-07 | Hygeia Sciences, Inc. | Immunoassay including lyophilized reactant mixture |
JPH03208485A (ja) * | 1990-01-11 | 1991-09-11 | Matsushita Electric Ind Co Ltd | 文字放送受信装置 |
US5200399A (en) * | 1990-09-14 | 1993-04-06 | Boyce Thompson Institute For Plant Research, Inc. | Method of protecting biological materials from destructive reactions in the dry state |
US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
US6509006B1 (en) | 1992-07-08 | 2003-01-21 | Inhale Therapeutic Systems, Inc. | Devices compositions and methods for the pulmonary delivery of aerosolized medicaments |
US7448375B2 (en) * | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
ES2218543T3 (es) * | 1994-03-07 | 2004-11-16 | Nektar Therapeutics | Procedimiento y preparacion para la administracion de insulina por via pulmonar. |
DE69530196T2 (de) | 1994-06-02 | 2003-11-20 | Elan Drug Delivery Ltd | Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen |
GB9508691D0 (en) | 1995-04-28 | 1995-06-14 | Pafra Ltd | Stable compositions |
US5876992A (en) | 1996-07-03 | 1999-03-02 | Molecular Biology Resources, Inc. | Method and formulation for stabilization of enzymes |
US6306404B1 (en) | 1998-07-14 | 2001-10-23 | American Cyanamid Company | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
FR2791895B1 (fr) * | 1999-03-23 | 2001-06-15 | Pasteur Merieux Serums Vacc | Utilisation de trehalose pour stabiliser un vaccin liquide |
US6635261B2 (en) | 1999-07-13 | 2003-10-21 | Wyeth Holdings Corporation | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
CA2464308A1 (fr) | 2001-10-22 | 2003-05-01 | Dompe S.P.A. | Traitement de fluides supercritiques : preparation de microparticules de proteines et leur stabilisation |
EP1490409B1 (fr) * | 2002-03-26 | 2008-12-31 | Novartis Vaccines and Diagnostics S.r.l. | Saccharides modifies presentant une stabilite amelioree dans l'eau |
US20030124139A1 (en) * | 2002-11-20 | 2003-07-03 | Irina Esikova | Compositions and methods for stabilizing biological molecules upon lyophilization |
GT200600112A (es) | 2005-03-14 | 2006-11-29 | Composiciiones de tigeciclina y metodos de preparacion | |
CA2611960C (fr) * | 2005-06-27 | 2015-05-05 | Glaxosmithkline Biologicals S.A. | Compositions immunogeniques comprenant des conjugues de saccharides capsulaires n.meningitidis |
GB0612854D0 (en) * | 2006-06-28 | 2006-08-09 | Novartis Ag | Saccharide analysis |
CN102803483B (zh) | 2009-06-12 | 2014-04-30 | 精密公司 | 用于微流体装置中taq 聚合酶的干燥储存的可再水合基质 |
WO2010144683A2 (fr) | 2009-06-12 | 2010-12-16 | Micronics, Inc. | Compositions et procédés pour le stockage à l'état déshydraté de réactifs sur puce dans des dispositifs microfluidiques |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB995362A (en) * | 1962-05-11 | 1965-06-16 | Smith Kline French Lab | Improvements in or relating to freeze-drying biological material |
FR1588829A (fr) * | 1967-06-22 | 1970-03-16 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2908614A (en) * | 1954-08-10 | 1959-10-13 | Glaxo Lab Ltd | Use of dextran in freeze-drying process |
US3135663A (en) * | 1960-06-28 | 1964-06-02 | Glaxo Group Ltd | Vaccines |
DE1183629B (de) * | 1962-12-21 | 1964-12-17 | Behringwerke Ag | Verfahren zur Stabilisierung biologisch aktiven Materials |
US3567585A (en) * | 1963-07-12 | 1971-03-02 | Ciba Geigy Corp | Process for obtaining bcg-cultures |
US3532790A (en) * | 1968-02-23 | 1970-10-06 | Canadian Patents Dev | Somatic antigen vaccines from lysed inactivated bacteria and process for producing them |
FR7461M (fr) * | 1968-06-19 | 1970-01-05 | ||
GB1218277A (en) * | 1968-08-20 | 1971-01-06 | Miles Lab | Dry water-dispersible aluminium hydroxide gels |
US3577527A (en) * | 1969-01-27 | 1971-05-04 | Us Navy | Neisseria meningitidis antigen |
US3599150A (en) * | 1969-08-01 | 1971-08-10 | Miles Lab | Stabilized aluminum hydroxide suspensions |
US3636192A (en) * | 1970-01-13 | 1972-01-18 | Us Army | Meningococcal polysaccharide vaccines |
US3859434A (en) * | 1973-01-08 | 1975-01-07 | Canadian Patents Dev | Meningococcal antigens |
-
1977
- 1977-10-27 DE DE19772748132 patent/DE2748132A1/de active Granted
-
1978
- 1978-10-21 ES ES474412A patent/ES474412A1/es not_active Expired
- 1978-10-25 SE SE7811083A patent/SE447700B/sv not_active IP Right Cessation
- 1978-10-25 US US05/954,461 patent/US4206200A/en not_active Expired - Lifetime
- 1978-10-25 FI FI783250A patent/FI61807B/fi not_active Application Discontinuation
- 1978-10-26 DK DK477278A patent/DK158006C/da not_active IP Right Cessation
- 1978-10-26 CA CA314,311A patent/CA1113861A/fr not_active Expired
- 1978-10-27 BE BE191411A patent/BE871612A/fr not_active IP Right Cessation
- 1978-10-27 FR FR7830616A patent/FR2406999A1/fr active Granted
- 1978-10-27 JP JP13173878A patent/JPS5470422A/ja active Granted
- 1978-10-27 GB GB7842190A patent/GB2009198B/en not_active Expired
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB995362A (en) * | 1962-05-11 | 1965-06-16 | Smith Kline French Lab | Improvements in or relating to freeze-drying biological material |
FR1588829A (fr) * | 1967-06-22 | 1970-03-16 |
Non-Patent Citations (1)
Title |
---|
CA1977 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0072513A2 (fr) * | 1981-08-14 | 1983-02-23 | Smithkline Biologicals S.A. | Procédé de préparation de polysaccharides bactériens capsulaires antigéniques purifiés, produits obtenus et leur utilisation |
EP0072513A3 (en) * | 1981-08-14 | 1986-02-19 | Smith Kline - Rit Societe Anonyme Dite: | Process for the preparation of purified bacterial capsular antigenic polysaccharides, the obtained products and their use |
GB2187191A (en) * | 1984-01-30 | 1987-09-03 | Quadrant Bioresources Ltd | Protection of proteins and the like |
GB2187191B (en) * | 1984-01-30 | 1989-11-01 | Quadrant Bioresources Ltd | Protection of proteins and the like |
WO1987000196A1 (fr) * | 1985-07-09 | 1987-01-15 | Quadrant Bioresources Limited | Protection des proteines et similaires |
Also Published As
Publication number | Publication date |
---|---|
DE2748132C2 (fr) | 1989-04-06 |
GB2009198A (en) | 1979-06-13 |
DK158006B (da) | 1990-03-12 |
FI61807B (fi) | 1982-06-30 |
GB2009198B (en) | 1982-10-27 |
SE447700B (sv) | 1986-12-08 |
FR2406999B1 (fr) | 1982-11-12 |
US4206200A (en) | 1980-06-03 |
SE7811083L (sv) | 1979-04-28 |
JPS5470422A (en) | 1979-06-06 |
JPS6310686B2 (fr) | 1988-03-08 |
DK477278A (da) | 1979-04-28 |
DK158006C (da) | 1990-08-06 |
CA1113861A (fr) | 1981-12-08 |
ES474412A1 (es) | 1979-04-16 |
BE871612A (fr) | 1979-04-27 |
DE2748132A1 (de) | 1979-05-03 |
FI783250A (fi) | 1979-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property |