FR2385388A1 - - Google Patents

Info

Publication number
FR2385388A1
FR2385388A1 FR7809666A FR7809666A FR2385388A1 FR 2385388 A1 FR2385388 A1 FR 2385388A1 FR 7809666 A FR7809666 A FR 7809666A FR 7809666 A FR7809666 A FR 7809666A FR 2385388 A1 FR2385388 A1 FR 2385388A1
Authority
FR
France
Prior art keywords
substance
capsules
micro
fragile
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7809666A
Other languages
French (fr)
Other versions
FR2385388B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of FR2385388A1 publication Critical patent/FR2385388A1/fr
Application granted granted Critical
Publication of FR2385388B1 publication Critical patent/FR2385388B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Abstract

L'invention a pour objet un comprimé ou autre article solide mis en forme, obtenu par compression, caractérisé en ce qu'il comprend une substance sous forme de microgélules ou une substance fragile par elle-même ou recouverte d'un revêtement fragile, et plus de 2 % poids/poids par rapport aux microgélules ou à la substance fragile d'une substance cireuse hydrosoluble naturelle ou synthétique ayant un point de fusion d'au moins 30 degrés C.The subject of the invention is a tablet or other shaped solid article, obtained by compression, characterized in that it comprises a substance in the form of micro-capsules or a substance which is fragile by itself or covered with a fragile coating, and more than 2% w / w based on the micro-capsules or the brittle substance of a natural or synthetic water-soluble waxy substance having a melting point of at least 30 degrees C.

FR7809666A 1977-04-01 1978-03-31 Expired FR2385388B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB13855/77A GB1598458A (en) 1977-04-01 1977-04-01 Tableting of microcapsules

Publications (2)

Publication Number Publication Date
FR2385388A1 true FR2385388A1 (en) 1978-10-27
FR2385388B1 FR2385388B1 (en) 1980-07-25

Family

ID=10030606

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7809666A Expired FR2385388B1 (en) 1977-04-01 1978-03-31

Country Status (12)

Country Link
JP (1) JPS53142520A (en)
AU (1) AU523028B2 (en)
BE (1) BE865633A (en)
CA (1) CA1110972A (en)
CH (1) CH640727A5 (en)
DE (1) DE2813146A1 (en)
DK (1) DK143078A (en)
FR (1) FR2385388B1 (en)
GB (1) GB1598458A (en)
IT (1) IT1095559B (en)
NL (1) NL7803496A (en)
SE (1) SE7803661L (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0196002A2 (en) * 1985-03-25 1986-10-01 Abbott Laboratories Tablet composition for drug combinations
EP0196546A2 (en) * 1985-03-25 1986-10-08 Abbott Laboratories Pharmaceutical tableting method
EP0355247A2 (en) * 1988-08-22 1990-02-28 Ss Pharmaceutical Co., Ltd. Compressed-molded preparations
FR2838647A1 (en) * 2002-04-23 2003-10-24 Ethypharm Sa Prolonged-release coated particles, for compression to tablets with unchanged release kinetics, comprising core of active agent and binder, cellulosic polymer film coating and outer thermoplastic protective film

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5873359A (en) * 1981-10-27 1983-05-02 旭化成株式会社 Production of pharmaceutical tablet
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
US4863741A (en) * 1985-03-25 1989-09-05 Abbott Laboratories Tablet composition for drug combinations
DE3532692A1 (en) * 1985-09-13 1987-03-19 Boehringer Mannheim Gmbh METHOD FOR PRODUCING TABLETS FROM PELLETS
EP0265457A4 (en) * 1986-04-10 1989-07-26 Daratech Pty Ltd Vaccine and implant.
US5811128A (en) * 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5009897A (en) * 1988-06-24 1991-04-23 Abbott Laboratories Pharmaceutical granules and tablets made therefrom
ES2052245T3 (en) * 1988-12-28 1994-07-01 Taisho Pharmaceutical Co Ltd VOLTAGE DISPERSION PROCEDURE DURING A TABLET FORMATION OPERATION.
DE3933000A1 (en) * 1989-10-03 1991-04-11 Int Pharma Agentur Erosion-controlled active agent release system
EP0418596A3 (en) * 1989-09-21 1991-10-23 American Cyanamid Company Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
US5436011A (en) * 1993-04-16 1995-07-25 Bristol-Myers Squibb Company Solid pharmaceutical dosage form and a method for reducing abrasion
US5631024A (en) * 1995-05-22 1997-05-20 Enviroquest, Ltd. Medicaments for beneficial insects and method
GB9921933D0 (en) 1999-09-17 1999-11-17 Univ Gent Solid shaped articles comprising biologically active substances and a method for their production
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
EP1302304B1 (en) * 2000-06-20 2011-12-14 Sanwa Kagaku Kenkyusho Co., Ltd. Method of producing a nucleated molded article
KR100496749B1 (en) * 2000-07-05 2005-06-22 아사히 가세이 가부시키가이샤 Cellulose powder
CN102871979B (en) * 2000-09-01 2014-10-22 帕尔马亚有限公司 Slow release pharmaceutical preparation and method of administering same
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
FR2837100B1 (en) * 2002-03-18 2004-07-23 Flamel Tech Sa MODIFIED RELEASE MICROCAPSULE-BASED TABLETS
US20060263429A1 (en) 2005-05-20 2006-11-23 Hengsheng Feng Compressible mixture, compressed pharmaceutical compositions, and method of preparation thereof
SA07280459B1 (en) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. Tamper Resistant Oral Pharmaceutical Dosage Forms Comprising an Opioid Analgesic
UA110091C2 (en) * 2009-01-22 2015-11-25 CHRONOTHERAPY PHARMACEUTICAL COMPOSITION
JP6392355B2 (en) * 2013-09-13 2018-09-19 アール．ピー．シェーラー テクノロジーズ、エルエルシー Pellet-containing tablets
CN112490052A (en) 2020-11-19 2021-03-12 深圳市致尚科技股份有限公司 Multi-directional input device

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB908282A (en) * 1958-02-18 1962-10-17 Wellcome Found Coated pharmaceutical granules and tablets thereof
AU5865665A (en) * 1965-05-11 1966-11-17 Compositions for anorectic use
BE724945A (en) * 1967-12-06 1969-06-05
US3557279A (en) * 1969-06-12 1971-01-19 Merck & Co Inc Microencapsulation form of an anti-inflammatory drug
DE1617657A1 (en) * 1966-11-23 1971-09-02 Merck & Co Inc Depot tablet
DE1792365A1 (en) * 1964-05-20 1972-03-09 Bristol Myers Co Antibiotic agent and process for its manufacture
FR2106566A1 (en) * 1970-09-16 1972-05-05 Merck & Co Inc Tabletting active materials - by compressing encapsulated particles

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB908282A (en) * 1958-02-18 1962-10-17 Wellcome Found Coated pharmaceutical granules and tablets thereof
DE1792365A1 (en) * 1964-05-20 1972-03-09 Bristol Myers Co Antibiotic agent and process for its manufacture
AU5865665A (en) * 1965-05-11 1966-11-17 Compositions for anorectic use
DE1617657A1 (en) * 1966-11-23 1971-09-02 Merck & Co Inc Depot tablet
BE724945A (en) * 1967-12-06 1969-06-05
US3557279A (en) * 1969-06-12 1971-01-19 Merck & Co Inc Microencapsulation form of an anti-inflammatory drug
FR2106566A1 (en) * 1970-09-16 1972-05-05 Merck & Co Inc Tabletting active materials - by compressing encapsulated particles

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0196002A2 (en) * 1985-03-25 1986-10-01 Abbott Laboratories Tablet composition for drug combinations
EP0196546A2 (en) * 1985-03-25 1986-10-08 Abbott Laboratories Pharmaceutical tableting method
EP0196546A3 (en) * 1985-03-25 1987-10-07 Abbott Laboratories Pharmaceutical tableting method
EP0196002B1 (en) * 1985-03-25 1991-07-03 Abbott Laboratories Tablet composition for drug combinations
EP0355247A2 (en) * 1988-08-22 1990-02-28 Ss Pharmaceutical Co., Ltd. Compressed-molded preparations
EP0355247A3 (en) * 1988-08-22 1990-12-12 Ss Pharmaceutical Co., Ltd. Compressed-molded preparations
US5186943A (en) * 1988-08-22 1993-02-16 Ss Pharmaceutical Co., Ltd. Compressed-molded preparations
US5275825A (en) * 1988-08-22 1994-01-04 Ss Pharmaceutical Co., Ltd. Compressed-molded preparations
FR2838647A1 (en) * 2002-04-23 2003-10-24 Ethypharm Sa Prolonged-release coated particles, for compression to tablets with unchanged release kinetics, comprising core of active agent and binder, cellulosic polymer film coating and outer thermoplastic protective film
WO2003090724A1 (en) * 2002-04-23 2003-11-06 Ethypharm Coated particles with prolonged release and tablets containing same

Also Published As

Publication number Publication date
FR2385388B1 (en) 1980-07-25
AU523028B2 (en) 1982-07-08
GB1598458A (en) 1981-09-23
DK143078A (en) 1978-10-02
DE2813146A1 (en) 1978-10-19
IT1095559B (en) 1985-08-10
AU3465178A (en) 1979-10-04
CA1110972A (en) 1981-10-20
CH640727A5 (en) 1984-01-31
JPS53142520A (en) 1978-12-12
IT7821797A0 (en) 1978-03-30
BE865633A (en) 1978-10-03
SE7803661L (en) 1978-10-02
NL7803496A (en) 1978-10-03

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Legal Events

Date Code Title Description
ST Notification of lapse